Department of Biomedical Sciences

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  1. 2022
  2. Published

    Reconstructing the Origins of the Somatostatin and Allatostatin-C Signaling Systems Using the Accelerated Evolution of Biodiverse Cone Snail Toxins

    Koch, Thomas Lund, Ramiro, Iris Bea L. , Flórez Salcedo, P., Engholm, E., Jensen, Knud Jørgen, Chase, K., Olivera, B. M., Bjørn-Yoshimoto, Walden, Safavi-hemami, H. & True, J. (ed.), 2022, In: Molecular Biology and Evolution. 39, 4, 20 p., msac075.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Bacterial biofilms predominate in both acute and chronic human lung infections

    Kolpen, Mette, Kragh, K. N., Enciso, J. B., Faurholt-Jepsen, D., Lindegaard, Birgitte, Egelund, G. B., Jensen, A. V., Ravn, P., Mathiesen, I. H. M., Gheorghe, Alexandra Gabriella, Hertz, Frederik Boëtius, Qvist, T., Whiteley, M., Jensen, Peter Østrup & Bjarnsholt, Thomas, 2022, In: European Respiratory Journal. Supplement. 60, Suppl. 66, 4.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study

    Koopen, A., Witjes, J., Wortelboer, K., Majait, S., Prodan, A., Levin, E., Herrema, H., Winkelmeijer, M., Aalvink, S., Bergman, J. J. G. H. M., Havik, S., Hartmann, B., Levels, H., Bergh, P-O., van Son, J., Balvers, M., Bastos, D. M., Stroes, E., Groen, A. K., Henricsson, M. & 8 others, Kemper, E. M., Holst, Jens Juul, Strauch, C. M., Hazen, S. L., Backhed, F., De Vos, W. M., Nieuwdorp, M. & Rampanelli, E., 2022, In: Gut. 71, p. 1577-1587 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A randomized double-blind single center study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig cell insufficiency (Einstein-intervention)

    Kreiberg, M., Jørgensen, N., Juul, Anders, Lauritsen, J., Oturai, P., Helge, Jørn Wulff, Christensen, J. F., Aksglaede, L., Schauer, T., Wagner, T., Rosenvilde, J., Grunwald, E., Dehlendorff, C., Daugaard, G. & Bandak, M., 2022, In: Clinical Genitourinary Cancer. 20, 5, p. 404-414 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Necropsy Validation of a Novel Method for Left Ventricular Mass Quantification in Porcine Transthoracic and Transdiaphragmal Echocardiography

    Kristensen, C. B., Sattler, Stefan M, Lubberding, Anniek Frederike, Tfelt-Hansen, Jacob, Jespersen, Thomas, Hassager, Christian & Mogelvang, R., 2022, In: Frontiers in Cardiovascular Medicine. 9, 868603.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Validity and reliability of the Danish version of the pregnancy physical activity questionnaire to assess levels of physical activity during pregnancy

    Kroner, F. H., Knudsen, S. D. P., Roland, Caroline Borup, Alomairah, S. A. & Mølsted, Stig, 2022, In: Journal of Maternal - Fetal & Neonatal Medicine. 35, 23, p. 4566–4572 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Severity of congenital long QT syndrome disease manifestation and risk of depression, anxiety, and mortality: a nationwide study

    Krøll, J., Jensen, H. K., Jespersen, C., Kanters, Jørgen K., Hansen, M. S., Christiansen, M., Westergaard, L. M., Fosbøl, Emil Loldrup, Rørth, R., Torp-Pedersen, Christian, Køber, Lars Valeur, Bundgård, Henning, Tfelt-Hansen, Jacob & Weeke, P. E., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 4, p. 620–629

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The effect of 8 weeks of physical training on muscle performance and maximal fat oxidation rates in patients treated with simvastatin and coenzyme Q10 supplementation

    Kuhlman, A. B., Mikkelsen, L. B., Regnersgaard, S., Heinrichsen, S., Nielsen, F. H., Frandsen, J., Orlando, P., Silvestri, S., Larsen, Steen, Helge, Jørn Wulff & Dela, Flemming, 2022, In: Journal of Physiology. 600, 3, p. 569-581 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Deepaware: A hybrid deep learning and context-aware heuristics-based model for atrial fibrillation detection

    Kumar, D., Peimankar, A., Sharma, K., Dominguez, Helena, Puthusserypady, S. & Bardram, J. E., 2022, In: Computer Methods and Programs in Biomedicine. 221, 11 p., 106899.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Enterohepatic, gluco-metabolic, and gut microbial characterization of individuals with bile acid malabsorption

    Kårhus, M. L., Sonne, David Peick, Thomasen, M., Ellegaard, A., Holst, Jens Juul, Rehfeld, Jens Frederik, Chávez-Talavera, O., Tailleux, A., Staels, B., Nielsen, Dennis Sandris, Dragsted, Lars Ove, Vilsbøll, Tina, Brønden, A. & Knop, Filip Krag, 2022, In: Gastro Hep Advances. 1, 3, p. 299-312 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Reaching Frail Elderly Patients to Optimize Diagnosis and Management of Atrial Fibrillation (REAFEL): A Feasibility Study of a Cross-Sectoral Shared-Care Model

    Ladegaard, C. T., Bamberg, C., Aalling, M., Jensen, D. M., Kamstrup-Larsen, Nina Katrine, Madsen, C. V., Kamil, S., Gudbergsen, Henrik Rindel, Saxild, T., Schiotz, M. L., Grew, J., Castillo, L. S., Frolich, A. & Dominguez, Helena, 2022, In: International Journal of Environmental Research and Public Health. 19, 12, 10 p., 7383.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Associations Between Albuminuria, Estimated GFR and Cardiac Phenotype in a Cohort with Chronic Kidney Disease: The CPH-CKD ECHO Study

    Landler, N. E., Olsen, F. J., Christensen, J., Bro, S., Feldt-Rasmussen, Bo, Hansen, Ditte, Kamper, A., Christoffersen, Christina, Ballegaard, E. L. F., Sørensen, I. M. H., Bjergfelt, S. S., Seidelin, E., Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2022, In: Journal of Cardiac Failure. 28, 11, p. 1615-1627 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Fibroblast growth factor 21 is the main alcohol responsive peptide hormone in humans and individuals with alcohol use disorder exihibit increased plasma concentrations after alcohol intake

    Lanng, A., Gasbjerg, Lærke Smidt, Sucksdorff, A., Svenningsen, J., Trammell, Sam, Vilsbøll, Tina, Gillum, M. & Knop, Filip Krag, 2022, In: Journal of Hepatology. 77, S1, p. S121-S121 1 p., THU006.

    Research output: Contribution to journal › Conference abstract in journal › Research

  15. Published

    Atrial cardiomyopathy in patients with ischaemic stroke: a cross-sectional and prospective cohort study-the COAST study

    Larsen, B. S., Aplin, M., Høst, N., Dominguez, Helena, Christensen, Hanne Krarup, Christensen, Louisa Marguerite, Havsteen, I., Prescott, Eva, Jensen, G. B., Vejlstrup, N., Bertelsen, L. & Sajadieh, Ahmad, 2022, In: BMJ Open. 12, 5, e061018.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Left Atrial Volumes and Function, and Long-Term Incidence of Ischemic Stroke in the General Population

    Larsen, B. S., Olsen, F. J., Andersen, D. M., Madsen, C. V., Møgelvang, R., Jensen, G. B., Schnohr, P., Aplin, M., Høst, N. B., Christensen, Hanne Krarup, Sajadieh, Ahmad & Biering-Sørensen, Tor, 2022, In: Journal of the American Heart Association. 11, 18, 10 p., e027031.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Identification of a conserved chemokine receptor motif that enables ligand discrimination

    Larsen, Olav, van der Velden, W. J. C., Mavri, M., Schuermans, S., Rummel, P. C., Karlshøj, S., Gustavsson, Martin, Proost, P., Våbenø, J. & Rosenkilde, Mette, 2022, In: Science Signaling. 15, 724, eabg7042.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Anatomical validation of automatic respiratory motion correction for coronary 18F-sodium fluoride positron emission tomography by expert measurements from four-dimensional computed tomography

    Lassen, M. L., Tzolos, E., Pan, T., Kwiecinski, J., Cadet, S., Dey, D., Berman, D. & Slomka, P., 2022, In: Medical Physics. 49, 11, p. 7085-7094

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Aortic valve imaging using 18F-sodium fluoride: impact of triple motion correction

    Lassen, M. L., Tzolos, E., Massera, D., Cadet, S., Bing, R., Kwiecinski, J., Dey, D., Berman, D. S., Dweck, M. R., Newby, D. E. & Slomka, P. J., 2022, In: EJNMMI Physics. 9, 1, p. 1-15 4.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Image-derived and physiological markers to predict adequate adenosine-induced hyperemic response in Rubidium-82 myocardial perfusion imaging

    Lassen, M. L., Wissenberg, M., Byrne, C., Sheykhzade, Majid, Hurry, P. K., Schmedes, A. V., Kjær, Andreas & Hasbak, P., 2022, In: Journal of Nuclear Cardiology. 29, p. 3207–3217

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Optimization of the left ventricle ejection fraction estimate obtained during cardiac adenosine stress 82Rubidium-PET scanning: impact of different reconstruction protocols

    Lassen, M. L., Wissenberg, M., Byrne, C., Kjær, Andreas & Hasbak, P., 2022, In: Journal of Nuclear Cardiology. 29, p. 3369–3378

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Sex differences and caffeine impact in adenosine-induced hyperemia

    Lassen, M. L., Byrne, C., Sheykhzade, Majid, Wissenberg, M., Hurry, P. K., Schmedes, A. V., Kjær, Andreas & Hasbak, P., 2022, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 63, 3, p. 431-437 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Unconventional insulins from predators and pathogens

    Laugesen, Sophie Heiden, Chou, D. H. C. & Safavi, Helena, 2022, In: Nature Chemical Biology. 18, 7, p. 688-697

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Neonatal Anthropometrics and Obesity Treatment Response in Children and Adolescents

    Lausten-Thomsen, U., Lund, Morten Asp Vonsild, Stinson, Sara, Frithioff-Bøjsøe, C., Holm, L. A., Baker, J. L., Fonvig, Cilius Esmann, Christiansen, M., Ängquist, Lars, Hansen, Torben & Holm, Jens-Christian, 2022, In: Journal of Pediatrics. 242, p. 74-78.e2 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity

    Lee, B., Sosnovtseva, Olga, Sorensen, Charlotte Mehlin & Postnov, D. D., 2022, In: Biomedical Optics Express. 13, 4, p. 2312-2322 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The assessment of cortical hemodynamic responses induced by tubuloglomerular feedback using in vivo imaging

    Lee, B., Postnov, D. D., Sorensen, Charlotte Mehlin & Sosnovtseva, Olga, 2022, bioRxiv, 17 p.

    Research output: Working paper › Preprint › Research

  27. Published

    Atrial fibrillation during the blanking period post ablation correlates with long-term recurrence: myth vs reality

    Levine, Y. C., Ifedili, I. & Dr Linz, Dominik Karl, 2022, In: Journal of Interventional Cardiac Electrophysiology. 65, p. 351–352 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  28. Published

    The elephant in the inbox

    Lewis, Christopher T.A. , 2022, In: Science. 378, 6621, p. 719-719

    Research output: Contribution to journal › Letter › Research › peer-review

  29. Published

    Cysteine residues are responsible for the sulfurous off-flavor formed in heated whey protein solutions

    Li, C., Paulsen, P. A., Akıllıoğlu, G., Nielsen, S. B., Engholm-Keller, Kasper & Lund, Marianne N., 2022, In: Food Chemistry: Molecular Sciences. 5, 9 p., 100120.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Oxidation of Whey Proteins during Thermal Treatment Characterized by a Site-Specific LC–MS/MS-Based Proteomic Approach

    Li, C., Nielsen, S. B., Engholm-Keller, Kasper & Lund, Marianne N., 2022, In: Journal of Agricultural and Food Chemistry. 70, 14, p. 4391-4406

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Site-Specific Characterization of Heat-Induced Disulfide Rearrangement in Beta-Lactoglobulin by Liquid Chromatography–Mass Spectrometry

    Li, C., Engholm-Keller, Kasper & Lund, Marianne N., 2022, In: Journal of Agricultural and Food Chemistry. 70, 3, p. 847-856

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Sea Urchin Polyketide Synthase SpPks1 Produces the Naphthalene Precursor to Echinoderm Pigments

    Li, F., Lin, Z., Torres, Joshua, Hill, E. A., Li, D., Townsend, C. A. & Schmidt, E. W., 2022, In: Journal of the American Chemical Society. 144, p. 9363−9371

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    PcoB is a defense outer membrane protein that facilitates cellular uptake of copper

    Li, P., Nayeri, N., Górecki, K., Becares, E. R., Wang, Kaituo, Mahato, D. R., Andersson, M., Abeyrathna, S. S., Lindkvist-Petersson, K., Meloni, G., Missel, Julie Winkel & Gourdon, Pontus Emanuel, 2022, In: Protein Science. 31, 7, p. 1-16 e4364.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria

    Li, P., Hendricks, A. L., Wang, Y., Villones, R. L. E., Lindkvist-Petersson, K., Meloni, G., Cowan, J. A., Wang, Kaituo & Gourdon, Pontus Emanuel, 2022, In: Nature Communications. 13, 1, 12 p., 4339.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Formation of whey protein aggregates by partial hydrolysis and reduced thermal treatment

    Li, R., Lund, P., Nielsen, S. B. & Lund, Marianne N., 2022, In: Food Hydrocolloids. 124, 9 p., 107206.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    A guide to adhesion GPCR research

    Liebscher, I., Cevheroglu, O., Hsiao, C., Maia, A. F., Schihada, H., Scholz, N., Soave, M., Spiess, Katja, Trajkovic, K., Kosloff, M. & Proemel, S., 2022, In: FEBS Journal. 289, 24, p. 7610-7630

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Association of type 1 diabetes and educational achievement in 16-20-year-olds: A Danish nationwide register study

    Lindkvist, E. B., Thorsen, S. U., Paulsrud, C., Thingholm, P. R., Eriksen, T. L. M., Gaulke, A., Skipper, N. & Svensson, Jannet, 2022, In: Diabetic Medicine. 39, 2, 10 p., 14673.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The Location of Missense Variants in the Human GIP Gene Is Indicative for Natural Selection

    Lindquist, Peter, Gasbjerg, Lærke Smidt, Mokrosinski, J., Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, Mette, 2022, In: Frontiers in Endocrinology. 13, 14 p., 891586.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Mechanisms and Therapeutic Opportunities in Atrial Fibrillation in Relationship to Alcohol Use and Abuse

    Linz, Benedikt Maximilian, Hertel, Julie Norup, Jespersen, Thomas & Dr Linz, Dominik Karl, 2022, In: Canadian Journal of Cardiology. 38, 9, p. 1352-1363

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    Pharmacological inhibition of acetylcholine-regulated potassium current (IK,ACh) prevents atrial arrhythmogenic changes in a rat model of repetitive obstructive respiratory events

    Linz, Benedikt Maximilian, Thostrup, A. H., Saljic, Arnela, Rombouts, K., Hertel, Julie Norup, Hohl, M., Milnes, J., Tfelt-Hansen, Jacob, Dr Linz, Dominik Karl & Jespersen, Thomas, Feb 2022, In: Heart Rhythm O2. 3, 1, p. 97-104

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Sleep apnea and atrial fibrillation: challenges in clinical and translational research

    Linz, Benedikt Maximilian, Hertel, Julie Norup, Hendriks, J., Saljic, Arnela, Dobrev, D., Baumert, M., Jespersen, Thomas & Dr Linz, Dominik Karl, 2022, In: Expert Review of Cardiovascular Therapy. 20, 2, p. 101-109

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Longitudinal sleep apnea burden monitoring: Implications for future smart wearable- and implantable- devices

    Dr Linz, Dominik Karl, 2022, In: International Journal of Cardiology. 357, p. 46-47 2 p.

    Research output: Contribution to journal › Editorial › Research

  43. Published

    Sinus rhythm: the sine qua non for rhythm control?

    Dr Linz, Dominik Karl & McIntyre, W. F., 29 Aug 2022, In: European Heart Journal. 43, 40, p. 4145–4147 3 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  44. Published

    Multi-Omics Analysis Reveals Changes in the Intestinal Microbiome, Transcriptome, and Methylome in a Rat Model of Chronic Non-bacterial Prostatitis: Indications for the Existence of the Gut-Prostate Axis

    Liu, J., Wang, Y., Zhang, G., Liu, L. & Peng, X., 2022, In: Frontiers in Physiology. 12, 12 p., 753034.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Reduction of 64Cu-DOTATATE activity dose for somatostatin receptor PET imaging of patients with neuroendocrine neoplasms

    Loft, Mathias Hougaard, Carlsen, Esben Andreas, Johnbeck, C. B., Jensen, C. V., Andersen, Flemming Littrup, Langer, Seppo W., Otorai, P., Knigge, Ulrich & Kjær, Andreas, 2022, In: Journal of Neuroendocrinology. 34, S1, p. 151-151 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  46. Published

    Activity Dose Reduction in 64Cu-DOTATATE PET in Patients with Neuroendocrine Neoplasms: Impact on Image Quality and Lesion Detection Ability.

    Loft, M., Carlsen, Esben Andreas, Johnbeck, C. B., Jensen, C. V., Andersen, Flemming Littrup, Langer, Seppo W., Oturai, P., Knigge, Ulrich & Kjær, Andreas, 2022, In: Molecular Imaging and Biology. 24, p. 600–611

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    First-in-Human PET Imaging of Tissue Factor in Patients with Primary and Metastatic Cancers Using 18F-labeled Active-Site Inhibited Factor VII (18F-ASIS): Potential as Companion Diagnostic

    Loft, Mathias Hougaard, Christensen, C., Clausen, Malene Martini, Carlsen, Esben Andreas, Hansen, C. P., Kroman, Niels Thorndahl, Langer, Seppo W., Høgdall, Claus Kim, Madsen, J., Gillings, N., Nielsen, Carsten Haagen, Klausen, Thomas Levin, Holm, S., Loft, A., Berthelsen, A. K. & Kjær, Andreas, 2022, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 63, 12, p. 1871-1879

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Increased mitochondrial proton leak and glycolysis in peripheral blood mononuclear cells in type-1-diabetes

    Lopes de Melo, J. M., Laursen, J. C., Søndergaard-Heinrich, N., Bull Rasmussen, I. K., Hansen, C. S., Frimodt-Møller, M., Rossing, Peter & Størling, Joachim, 2022, In: Heliyon. 8, 12, 7 p., e12304.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Proteomic Characterization of Atherosclerotic Lesions in Situ Using Percutaneous Coronary Intervention Angioplasty Balloons-Brief Report

    Lorentzen, Lasse Gøbel, Hansen, G. M., Iversen, Kasper, Bundgård, Henning & Davies, Michael J., 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 7, p. 857-864

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Celebrities in the heart, strangers in the pancreatic beta cell: Voltage-gated potassium channels Kv7.1 and Kv11.1 bridge long QT syndrome with hyperinsulinaemia as well as type 2 diabetes

    Lubberding, Anniek Frederike, Juhl, C. R., Skovhøj, Emil Zeng, Kanters, Jørgen K., Mandrup-Poulsen, Thomas & Torekov, Signe Sørensen, 2022, In: Acta Physiologica. 234, 3, 18 p., 13781.

    Research output: Contribution to journal › Review › Research › peer-review

  51. Published

    Effect of Processing of Whey Protein Ingredient on Maillard Reactions and Protein Structural Changes in Powdered Infant Formula

    Lund, P., Bechshoft, M. R., Ray, C. A. & Lund, Marianne N., 2022, In: Journal of Agricultural and Food Chemistry. 70, 1, p. 319–332

    Research output: Contribution to journal › Journal article › Research › peer-review

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