Department of Biomedical Sciences

  1. 2022
  2. Published

    Effect of hydroxychloroquine on the cardiac ventricular repolarization: A randomized clinical trial

    Eveleens Maarse, B. C., Graff, C., Kanters, Jørgen K., van Esdonk, M. J., Kemme, M. J. B., in 't Veld, A. E., Jansen, M. A. A., Moerland, M. & Gal, P., Mar 2022, In: British Journal of Clinical Pharmacology. 88, 3, p. 1054-1062 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A distinct dexamethasone-dependent gene expression profile in the lungs of COVID-19 patients

    Fahnøe, Ulrik, Ronit, A., Berg, Ronan Martin Griffin, Jørgensen, S. E., Mogensen, T. H., Underwood, Alexander Paul James, Scheel, Troels Kasper Høyer, Bukh, Jens & Plovsing, R. R., 2022, In: The Journal of Infectious Diseases. 226, 12, p. 2137–2141

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Gastrointestinal Hormones and β-Cell Function After Gastric Bypass and Sleeve Gastrectomy: A Randomized Controlled Trial (Oseberg)

    Fatima, F., Hjelmesæth, J., Birkeland, K. I., Hanne, G. L., Hertel, J. K., Svanevik, M., Sandbu, R., Småstuen, M. C., Hartmann, Bolette, Holst, Jens Juul & Hofsø, D., 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 2, p. e756-e766 11 p., dgab643.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Nanomolar EP4 receptor potency and expression of eicosanoid-related enzymes in normal appearing colonic mucosa from patients with colorectal neoplasia

    Feddersen, U. R., Hendel, S. K., Berner-Hansen, M. A., Jepps, T. A. & Bindslev, Niels, 2022, In: BMC Gastroenterology. 22, 1, p. 1-11 234.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Role of amino acid oxidation and protein unfolding in peroxyl radical and peroxynitrite-induced inactivation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides

    Figueroa, J. D., Fuentes Lemus, Eduardo, Reyes, J. S., Loaiza, M., Aliaga, M. E., Fierro, A., Leinisch, F., Hägglund, Per Mårten, Davies, Michael J. & López-Alarcón, C., 2022, In: Free Radical Biology and Medicine. 190, p. 292-306

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Early clinical and pre-clinical therapy development in Nemaline myopathy

    Fisher, G., Mackels, L., Markati, T., Sarkozy, A., Ochala, Julien, Jungbluth, H., Ramdas, S. & Servais, L., 28 Dec 2022, In: Expert Opinion On Therapeutic Targets. 26, 10, p. 853–867

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Effects of Adaptive Servo-Ventilation on Nocturnal Ventricular Arrhythmia in Heart Failure Patients With Reduced Ejection Fraction and Central Sleep Apnea–An Analysis From the SERVE-HF Major Substudy

    Fisser, C., Gall, L., Bureck, J., Vaas, V., Priefert, J., Fredersdorf, S., Zeman, F., Dr Linz, Dominik Karl, Woehrle, H., Tamisier, R., Teschler, H., Cowie, M. R. & Arzt, M., 2022, In: Frontiers in Cardiovascular Medicine. 9, 10 p., 896917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Extreme duration exercise affects old and younger men differently

    Frandsen, J., Sahl, R. E., Rømer, T., Thunestvedt Hansen, M., Nielsen, A. B., Lie-Olesen, M. M., Rasmusen, H. K., Søgaard, D., Ingersen, A., Rosenkilde, M., Westerterp, K., Holst, J. J., Andersen, J. L., Markowski, A. R., Blachnio-Zabielska, A., Clemmensen, C., Sacchetti, M., Cataldo, A., Traina, M., Larsen, S. & 2 others, Dela, Flemming & Helge, Jørn Wulff, 2022, In: Acta Physiologica. 235, 3, e13816.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Denervation-induced muscle atrophy - saved by the lysosomes

    Frank, E., Jul 2022, In: The Journal of Physiology. 600, 14, p. 3217-3218 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  11. Published

    Regional longitudinal strain patterns according to left ventricular hypertrophy in the general population

    Frimodt-Moller, K. E., Olsen, F. J., Biering-Sorensen, S. R., Lassen, M. C. H., Mogelvang, R., Schnohr, P., Jensen, G., Gislason, Gunnar Hilmar, Marcus, G. M. & Biering-Sørensen, Tor, 2022, In: European Heart Journal Cardiovascular Imaging. 23, 11, p. 1436–1444

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Early detection of childhood overweight and related complications in a Danish population-based cohort aged 2–8 years

    Frithioff-Bøjsøe, C., Lund, Morten Asp Vonsild, Lausten-Thomsen, U., Fonvig, Cilius Esmann, Lankjær, I. O. J., Hansen, T., Hansen, Torben, Baker, J. L. & Holm, Jens-Christian, 2022, In: Obesity Research and Clinical Practice. 16, 3, p. 228-234 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Crowding modulates the glycation of plasma proteins: In vitro analysis of structural modifications to albumin and transferrin and identification of sites of modification

    Fuentes Lemus, Eduardo, Reyes, J. S., López-Alarcón, C. & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 193, p. 551-566 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Oxidative Crosslinking of Peptides and Proteins: Mechanisms of Formation, Detection, Characterization and Quantification

    Fuentes Lemus, Eduardo, Hägglund, Per Mårten, López-Alarcón, C. & Davies, Michael J., 1 Jan 2022, In: Molecules. 27, 1, p. 1-31 15.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment

    Gabe, M. B. N., Skov-Jeppesen, Kirsa, Gasbjerg, Lærke Smidt, Schiellerup, S. P., Martinussen, C., Gadgaard, S., Boer, G. A., Oeke, J., Pedersen, Lola Julie Torz, Veedfald, Simon, Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: Pharmacological Research. 176, 106058.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction

    Gabe, M. B. N., Gasbjerg, Lærke Smidt, Gadgaard, S., Lindquist, Peter, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4473-4485

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Novel agonist- and antagonist-based radioligands for the GLP-2 receptor - useful tools for studies of basic GLP-2R pharmacology

    Gadgaard, S., van der Velden, W. J. C., Schiellerup, S. P., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Boer, G. A., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: British Journal of Pharmacology. 179, 9, p. 1998-2015

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published
  19. Published

    Development of18F-Labeled Bispyridyl Tetrazines for In Vivo Pretargeted PET Imaging

    García-Vázquez, R., Jørgensen, Jesper Tranekjær, Bratteby, K. E., Shalgunov, Vladimir, Hvass, Lars, Herth, Matthias Manfred, Kjær, Andreas & Battisti, Umberto Maria, 2022, In: Pharmaceuticals. 15, 2, 28 p., 245.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications

    Gawalko, M., Agbaedeng, T. A., Saljic, Arnela, Mueller, D. N., Wilck, N., Schnabel, R., Penders, J., Rienstra, M., van Gelder, I., Jespersen, Thomas, Schotten, U., Crijns, H. J. G. M., Kalman, J. M., Sanders, P., Nattel, S., Dobrev, D. & Dr Linz, Dominik Karl, 2022, In: Cardiovascular Research. 118, 11, p. 2415–2427

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Gastric Aspiration Improves Postprandial Glucose Tolerance Without Causing a Compensatory Increase in Appetite and Food Intake

    Gether, I. M., Jensen, M. M., Nexøe-Larsen, C. C., Jorsal, T., Gasbjerg, Lærke Smidt, Naver, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Obesity Surgery. 32, p. 1385–1390

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Association of Common and Rare Genetic Variation in the 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Gene and Cataract Risk

    Ghouse, Jonas, Ahlberg, Gustav, Skov, A. G., Bundgård, Henning & Olesen, Morten Steen Salling, 2022, In: Journal of the American Heart Association. 11, 12, p. 1-39 e025361.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Effect of Loss-of-Function Genetic Variants in PCSK9 on Glycemic Traits, Neurocognitive Impairment, and Hepatobiliary Function

    Ghouse, Jonas, Ahlberg, G., Bundgård, Henning & Olesen, Morten Steen Salling, 2022, In: Diabetes Care. 45, 1, p. 251-254

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Polygenic risk score for ACE-inhibitor-associated cough based on the discovery of new genetic loci

    Ghouse, J., Tragante, V., Muhammad, A., Ahlberg, G., Skov, M. W., Roden, D. M., Jonsdottir, I., Andreasen, L., Lundegaard, P. R., Trudsø, L. C., Banasik, K., Brunak, S., Ostrowski, S. R., Torp-Pedersen, C., Pedersen, O. V., Sørensen, E., Køber, L., Iversen, K., Thorsteinsdottir, U., Thorgeirsson, G. & 8 others, Ullum, H., Gudbjartsson, D. F., Mosley, J. D., Holm, H., Stefansson, K., Bundgård, Henning, Olesen, Morten Steen Salling & eMERGE consortium, E. C., 2022, In: European Heart Journal. 43, 45, p. 4707–4718

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Effectiveness and safety of P2Y12inhibitors in patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention: a nationwide registry-based study

    Godtfredsen, S. J., Kragholm, K. H., Leutscher, P., Jorgensen, S. H., Christensen, M. K., Butt, J. H., Gislason, Gunnar Hilmar, Køber, Lars Valeur, Fosbøl, Emil Loldrup, Sessa, Maurizio, Bhatt, D. L., Torp-Pedersen, Christian & Pareek, M., 2022, In: European Heart Journal: Acute Cardiovascular Care. 11, 9, p. 697–705

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    En hyldest til nordisk lægevidenskabelig forskning

    Goetze, Jens P. & Benfield, Thomas, 2022, In: Ugeskrift for Læger. 184, V205135.

    Research output: Contribution to journalEditorialResearch

  27. Published

    Microfluidic-Derived Detection of Protein-Facilitated Copper Flux Across Lipid Membranes

    Gorecki, K., Hansen, J. S., Li, P., Nayeri, N., Lindkvist-Petersson, K. & Gourdon, Pontus Emanuel, 2022, In: Analytical Chemistry. 94, 34, p. 11831-11837

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Postprandial dysfunction in metabolic associated fatty liver disease (MAFLD)

    Grandt, J., Jensen, A. S., Werge, M., Rashu, E., Junker, A., Hobolth, L., Mortensen, C., Kristiansen, M., Vyberg, M., Serizawa, R., Møller, Søren, Gluud, Lise Lotte & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Journal of Hepatology. 77, p. S154-S154 1 p., THU068.

    Research output: Contribution to journalConference abstract in journalResearch

  29. Published

    BIOMARKERS OF INFLAMMATION AND JOINT TISSUE TURNOVER CAN HELP IMPROVING THE DIFFERENTIATION BETWEEN OSTEOARTHRITIS AND PSORIATIC ARTHRITIS PATIENTS

    Groen, S. S., Nielsen, S. H., Bay-Jensen, A. C., Rasti, M., Ganatra, D., Oikonomopoulou, K. & Chandran, V., 2022, In: Annals of the Rheumatic Diseases. 81, Suppl. 1, p. 876-876 1 p., POS1097.

    Research output: Contribution to journalConference abstract in journalResearch

  30. Published

    SEROLOGICAL COLLAGEN BIOMARKERS CAN DIFFERENTIATE PATIENTS WITH PSORIASIS FROM PSORIATIC ARTHRITIS

    Groen, S. S., Nielsen, S. H., Bay-Jensen, A. C., Rasti, M., Ganatra, D., Oikonomopoulou, K. & Chandran, V., 2022, In: Annals of the Rheumatic Diseases. 81, p. 23-23 1 p., OP0031.

    Research output: Contribution to journalConference abstract in journalResearch

  31. Published

    Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats

    Grunddal, Kaare Villum, Trammell, Sam, Bæch-Laursen, C., Andersen, Daniel Bjørklund, Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, Ivana, Tyrberg, B., Li, C., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2022, In: Diabetologia. 65, p. 1018–1031

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Expression Profile of the GLP-1 Receptor in the Gastrointestinal Tract and Pancreas in Adult Female Mice

    Grunddal, Kaare Villum, Jensen, E. P., Ørskov, Cathrine, Andersen, Daniel Bjørklund, Windeløv, Johanne Agerlin, Poulsen, Steen Seier, Rosenkilde, M. M., Knudsen, L. B., Pyke, C. & Holst, Jens Juul, 2022, In: Endocrinology. 163, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Glucagon Clearance is Preserved in Type 2 Diabetes

    Grøndahl, M. F. G., Lund, A., Bagger, J. I., Petersen, Tonny Studsgaard, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Diabetes. 71, 1, db210024.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    The use of social media for professional purposes by healthcare professionals: the #intEHRAct survey

    Guerra, F., Dr Linz, Dominik Karl, Garcia, R., Kommata, V., Kosiuk, J., Chun, J., Boveda, S. & Duncker, D., 2022, In: Europace. 24, 4, p. 691-696 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    LEAP2 reduces postprandial glucose excursions and ad libitum food intake in healthy men

    Hagemann, C. A., Jensen, M. S., Holm, Stephanie Kjærulff, Gasbjerg, Lærke Smidt, Byberg, Sarah, Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Birgitte & Knop, Filip Krag, 2022, In: Cell Reports Medicine. 3, 4, 100582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Mapping the modification of histones by the myeloperoxidase-derived oxidant hypochlorous acid (HOCl)

    Hallberg, L. A. E., Thorsen, N. W., Hartsema, E. A., Hägglund, Per Mårten & Hawkins, Clare Louise, 2022, In: Free Radical Biology and Medicine. 192, p. 152-164 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Studies in Rats of Combined Muscle and Liver Perfusion and of Muscle Extract Indicate That Contractions Release a Muscle Hormone Directly Enhancing Hepatic Glycogenolysis

    Han, X. X., Holst, Jens Juul & Galbo, Henrik, 2022, In: Journal of Personalized Medicine. 12, 5, 12 p., 837.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Differential Internalization of Thrombin-Derived Host Defense Peptides into Monocytes and Macrophages

    Hansen, F. C., Nadeem, A., Browning, K. L., Campana, M., Schmidtchen, A. & van der Plas, Mariena J.A., 2022, In: Journal of Innate Immunity. 14, 5, p. 418–432

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Optimizing an immunomodulatory potency assay for Mesenchymal Stromal Cell

    Hansen, S. B., Højgaard, L. D., Kastrup, J., Ekblond, A., Follin, Bjarke & Juhl, M., 2022, In: Frontiers in Immunology. 13, 1085312.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Effect of influenza vaccination in solid organ transplant recipients: A nationwide population-based cohort study

    Harboe, Zitta F B Barrella, Modin, D., Gustafsson, Finn, Perch, Michael, Gislason, Gunnar Hilmar, Sørensen, Søren Schwartz, Rasmussen, A., Biering-Sørensen, Tor & Nielsen, Susanne Dam, 2022, In: American Journal of Transplantation. 22, 10, p. 2409-2417 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Regulation of the microvasculature during small muscle mass exercise in chronic obstructive pulmonary disease vs. chronic heart failure

    Hartmann, J. P., Dahl, R. H., Nymand, Stine Buus, Munch, G. W., Ryrsø, C. K., Pedersen, Bente Klarlund, Thaning, P., Mortensen, S. P., Berg, Ronan Martin Griffin & Iepsen, Ulrik Winning, 2022, In: Frontiers in Physiology. 13, 11 p., 979359.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The impact of age on the 99th percentile of cardiac troponin

    Hasselbalch, R., Strandkjaer, N., Kristensen, J., Joergensen, N., Kock, T. O., Ostrowski, Sisse Rye, Pedersen, Ole Birger Vesterager, Torp-Pedersen, Christian, Bundgård, Henning, Bor, V., Afzal, Shoaib, Kamstrup, P., Dahl, Morten, Hilsted, Linda & Iversen, Kasper, 2022, In: European Heart Journal. 43, Supplement_2, 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  43. Published

    Review: The evolution of peptidergic signaling in Cnidaria and Placozoa, including a comparison with Bilateria

    Hauser, Frank, Koch, Thomas Lund & Grimmelikhuijzen, Cornelis (Cok), Sep 2022, In: Frontiers in Endocrinology. 13, 18 p., 973862.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Left atrial strain predicts incident atrial fibrillation in the general population: the Copenhagen City Heart Study

    Hauser, R., Nielsen, A. B., Skaarup, K. G., Lassen, M. C. H., Duus, L. S., Johansen, N. D., Sengeløv, M., Marott, J. L., Jensen, G., Schnohr, P., Søgaard, P., Møgelvang, R. & Biering-Sørensen, Tor, 2022, In: European Heart Journal Cardiovascular Imaging. 23, 1, p. 52-60 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Genetic variation of macronutrient tolerance in Drosophila melanogaster

    Havula, E., Ghazanfar, S., Lamichane, N., Francis, D., Hasygar, K., Liu, Y., Alton, L. A., Johnstone, J., Needham, E. J., Pulpitel, T., Clark, T., Niranjan, H. N., Shang, V., Tong, V., Jiwnani, N., Audia, G., Alves, A. N., Sylow, L., Mirth, C., Neely, G. G. & 4 others, Yang, J., Hietakangas, V., Simpson, S. J. & Senior, A. M., 2022, In: Nature Communications. 13, 16 p., 1637.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published
  47. Published

    Characterization, Stability, and Antibrowning Effects of Oxyresveratrol Cyclodextrin Complexes Combined Use of Hydroxypropyl Methylcellulose

    He, Jianfei, Chen, H., Chen, H., Wang, B., Guo, F. & Zheng, Z., Aug 2022, In: Foods. 11, 16, 17 p., 2471.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Tolerable Duration of Warm Ischaemia After Circulatory Death Is Safe For At Least One Hour in Porcine Lungs: Functional Assessment with Ex Vivo Lung Perfusion

    Hebsgaard, M. M. B., Kissow, Hannelouise, Lilleør, N. B., Lorenzen, U. S., Chemtob, R. A., Møller-Sørensen, H., Olsen, P. S. & Møller, Christian H., 2022, In: Heart Surgery Forum. 25, 1, p. E48-E52 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Effect of Meal Texture on Postprandial Glucose Excursions and Gut Hormones After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy

    Hedbäck, N., Hindsø, M., Bojsen-Møller, K. N., Linddal, A. K., Jørgensen, N. B., Dirksen, C., Møller, A., Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul, Svane, M. S. & Madsbad, Sten, 2022, In: Frontiers in Nutrition. 9, 889710.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Preterm birth rates among twins during the Danish COVID-19 lockdown and mitigation period

    Hedley, P. L., Bækvad-Hansen, M., Hedermann, G., Hjalgrim, Henrik, Hougaard, D. M., Melbye, M., Breindahl, M., Krebs, Lone, Hviid, Anders Peter, Lausten-Thomsen, U. & Christiansen, Michael, 2022, medRxiv, 9 p.

    Research output: Working paperPreprintResearch

  51. Published

    A Nationwide Observational Study of Chlamydia trachomatis Infections in Denmark during the COVID-19 Pandemic

    Hedley, P. L., Hoffmann, S., Lausten-Thomsen, U., Voldstedlund, M., Bjerre, K. D., Hviid, Anders Peter, Krebs, Lone, Jensen, J. S. & Christiansen, M., 2022, In: Acta Dermato-Venereologica. 102, 5 p., adv00704.

    Research output: Contribution to journalJournal articleResearchpeer-review