Department of Biomedical Sciences

  1. 1998
  2. Published

    Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

    Deacon, Carolyn F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O. & Holst, Jens Juul, 1998, In: Diabetologia. 41, p. 271-278

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Long-range correlations of serial FEV1 measurements in emphysematous patients and normal subjects.

    Dirksen, A., von Holstein-Rathlou, Niels-Henrik, Madsen, F., Skovgaard, L. T., Søchting, Ulrik, Heckscher, T. & Kok-Jensen, A., 1998, In: Journal of Applied Physiology. 85, 1, p. 259-65 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Evaluation of Lama5 as a candidate for the mouse ragged (Ra) mutation.

    Durkin, M. E., Albrechtsen, Reidar, Chambers, D. M., Abbott, C. M. & Wewer, Ulla M., 1998, In: Biochemical and Biophysical Research Communications. 250, 1, p. 125-30 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans

    Flint, A., Raben, Anne, Astrup, A. & Holst, Jens Juul, 1998, In: Journal of Clinical Investigation. 101, 3, p. 515-520 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque

    Fu, S., Davies, Michael J., Stocker, R. & Dean, R. T., 1 Aug 1998, In: Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes

    Fuhlendorff, J., Rorsman, P., Kofod, H., Brand, C. L., Rolin, B., MacKay, P., Shymko, R. & Carr, R. D., Mar 1998, In: Diabetes. 47, 3, p. 345-51 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    90K (MAC-2 BP) gene expression in breast cancer and evidence for the production of 90K by peripheral-blood mononuclear cells.

    Fusco, O., Querzoli, P., Nenci, I., Natoli, C., Brakebusch, Cord Herbert, Ullrich, A. & Iacobelli, S., 1998, In: International Journal of Cancer. 79, 1, p. 23-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo.

    Gilpin, B. J., Loechel, F., Mattei, M. G., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 1998, In: Journal of Biological Chemistry. 273, 1, p. 157-66 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The K+ channels of colonic crypts and their regulation

    Greger, R., Hamm, K., Warth, R., Nielsen, Morten Schak, Weyand, B., Ecke, D., Riedemann, N., Gerlach, U., Busch, A. E., Englert, H. C., Hropot, M., Lang, H. J. & Bleich, M., 1998, In: Korean Journal of Physiology and Pharmacology. 2, 4, p. 403-409 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling

    Gromada, J., Bokvist, K., Ding, W. G., Holst, Jens Juul, Nielsen, Jens Høiriis & Rorsman, P., 1998, In: Diabetes. 47, 1, p. 57-65 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Characterization of the inhibitory effect of growth hormone on primary preadipocyte differentiation

    Hansen, L. H., Madsen, B., Teisner, B., Nielsen, Jens Høiriis & Billestrup, Nils, Aug 1998, In: Molecular endocrinology (Baltimore, Md.). 12, 8, p. 1140-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Degradation of hyaluronic acid, poly- and monosaccharides, and model compounds by hypochlorite: evidence for radical intermediates and fragmentation

    Hawkins, C. L. & Davies, Michael J., Jun 1998, In: Free Radical Biology & Medicine. 24, 9, p. 1396-410 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation

    Hawkins, C. L. & Davies, Michael J., 15 Jun 1998, In: Biochemical Journal. 332 ( Pt 3), p. 617-25 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.

    Holst, Jens Juul, Gromada, K. & Rorsman, P., 1998, In: Pflugers Arch.. 435, p. 583-594

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Glucagon-like peptide-1 - a new hormone and a new drug

    Holst, Jens Juul, 1998, In: Ugeskrift for læger. 160, p. 2371-2377

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes

    Holst, Jens Juul & Deacon, Carolyn F., 1998, In: Diabetes. 47, p. 1663-1670

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Nutrients of animal origin and function of gut hormones

    Holst, Jens Juul, 1998, Food and Health: Role of Animal Products. Paris: Elsevier, p. 13-22

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  19. Published

    Obesity - did anything happen since leptin?

    Holst, Jens Juul, 1998, In: Ugeskrift for læger. 160, p. 1182-1184

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    On the treatment of diabetes mellitus with glucagon-like peptide-1.

    Holst, Jens Juul, Deacon, Carolyn F., Toft-Nielsen, M. & Bjerre-Knudsen, L., 1998, In: Annals of the New York Academy of Sciences. 865, p. 336-343

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Regulatory Peptides of the Gut

    Holst, Jens Juul, 1998, Small Bowel Disorders. Kluwer Academic Publishers

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  22. Published

    Treatment of type 2 diabetes with glucagonlike peptide 1

    Holst, Jens Juul, 1998, In: Current Opinion in Endocrin. and Diabetes. 5, p. 108-115

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Blood pressure variability and kidney function.

    von Holstein-Rathlou, Niels-Henrik, Karlsen, F. M. & Leyssac, P. P., 1998, In: Fundamental and Clinical Pharmacology. 12 Suppl 1, p. 29s-34s

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    High value of the radiobiological parameter Dq correlates to expression of the transforming growth factor beta type II receptor in a panel of small cell lung cancer cell lines

    Hougaard, S., Krarup, M., Nørgaard, Peder, Damstrup, L., Spang-Thomsen, M. & Poulsen, H. S., 1998, In: Lung Cancer. 20, 1, p. 65-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Dynamics of spectral components of heart rate variability during changes in autonomic balance.

    Højgaard, M. V., von Holstein-Rathlou, Niels-Henrik, Agner, E. & Kanters, Jørgen K., 1998, In: American Journal of Physiology (Consolidated). 275, 1 Pt 2, p. H213-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Receptor-like protein-tyrosine phosphatase alpha specifically inhibits insulin-increased prolactin gene expression.

    Jacob, K. K., Sap, J. & Stanley, F. M., 1998, In: Journal of Biological Chemistry. 273, 8, p. 4800-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus

    Jensen, P. B., Blume, N., Mikkelsen, J. D., Larsen, P. J., Jensen, H. I., Holst, Jens Juul & Madsen, O. D., 1998, In: J. Clin. Invest.. 101, p. 503-510

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Steroid metabolism in the hormone dependent MCF-7 human breast carcinoma cell line and its two hormone resistant subpopulations MCF-7/LCC1 and MCF-7/LCC2

    Jørgensen, L., Brünner, N., Spang-Thomsen, M., James, M. R., Clarke, R., Dombernowsky, P. & Svenstrup, B., 1998, In: Journal of Steroid Biochemistry and Molecular Biology. 63, 4-6, p. 275-81 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Pig epidermal growth factor precursor contains segments that are highly conserved among species

    Jørgensen, P. E., Jensen, L. G., Sørensen, B. S., Poulsen, Steen Seier & Nexø, E., Jul 1998, In: Scandinavian Journal of Clinical & Laboratory Investigation. 58, 4, p. 287-98 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Novel donor splice site mutation in the KVLQT1 gene is associated with long QT syndrome

    Kanters, Jørgen K., Larsen, Lars Allan, Orholm, M., Agner, E., Andersen, P. S., Vuust, J. & Christiansen, M., 1 Jan 1998, In: Journal of Cardiovascular Electrophysiology. 9, 6, p. 620-624 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Tubuloglomerular feedback in Dahl rats.

    Karlsen, F. M., Leyssac, P. P. & von Holstein-Rathlou, Niels-Henrik, 1998, In: American Journal of Physiology (Consolidated). 274, 6 Pt 2, p. R1561-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Interleukin-15 and its role in chronic inflammatory diseases

    Kirman, I., Vainer, B. & Nielsen, Ole Haagen, 28 Aug 1998, In: Inflammation Research. 47, 7, p. 285-289 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    Neuronal histamine and expression of corticotropin-releasing hormone, vasopressin and oxytocin in the hypothalamus: Relative importance of H1 and H2 receptors

    Kjær, Andreas, Larsen, P. J., Knigge, Ulrich, Jørgensen, H. & Warberg, J., 1998, In: European Journal of Endocrinology. 139, 2, p. 238-243

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Expression of cell cycle regulating factor mRNA in small cell lung cancer xenografts

    Krarup, M., Poulsen, H. S. & Spang-Thomsen, M., 1998, In: Folia Microbiologica. 43, 5, p. 501-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Hormone-sensitive lipase (HSL) expression and regulation in skeletal muscle

    Langfort, J., Ploug, Thorkil, Ihlemann, J., Enevoldsen, L. H., Stallknecht, Bente Merete, Saldo, M., Kjær, Michael, Holm, C. & Galbo, Henrik, 1998, In: Advances in Experimental Medicine and Biology. 441, p. 219-28 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Outcome of combination chemotherapy in extensive stage small-cell lung cancer: any treatment related progress?

    Lassen, Ulrik Niels, Hirsch, F. R., Osterlind, K., Bergman, B. & Dombernowsky, P., Jun 1998, In: Lung Cancer. 20, 3, p. 151-60 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Solution structure of a syndecan-4 cytoplasmic domain and its interaction with phosphatidylinositol 4,5-bisphosphate.

    Lee, D., Oh, E. S., Woods, A., Couchman, John Robert & Lee, W., 1998, In: Journal of Biological Chemistry. 273, 21, p. 13022-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells

    Litman, Thomas, Pedersen, S. F., Kramhøft, B., Skovsgaard, T. & Hoffmann, E. K., 1998, In: Cellular Physiology and Biochemistry. 8, 3, p. 138-50 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Human ADAM 12 (meltrin alpha) is an active metalloprotease.

    Loechel, F., Gilpin, B. J., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 1998, In: Journal of Biological Chemistry. 273, 27, p. 16993-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake

    Lund, E. L., Quistorff, B., Spang-Thomsen, M. & Kristjansen, P. E., 1998, In: Folia Microbiologica. 43, 5, p. 505-6 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Tumor angiogenesis--a new therapeutic target in gliomas

    Lund, E. L., Spang-Thomsen, M., Skovgaard-Poulsen, H. & Kristjansen, P. E., 1998, In: Acta Neurologica Scandinavica. 97, 1, p. 52-62 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Poliosenfølger og postpolio: en oversigt

    Lønnberg, F., 1998, In: Ugeskrift for læger. 26, p. 3904-3908

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Direct detection of radicals in intact soybean nodules: presence of nitric oxide-leghemoglobin complexes

    Mathieu, C., Moreau, S., Frendo, P., Puppo, A. & Davies, Michael J., 1998, In: Free Radical Biology & Medicine. 24, 7-8, p. 1242-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    HTLV-1 infection in a population-based cohort of older persons in Guinea-Bissau, West Africa: Risk factors and impact on survival

    Melbye, M., Poulsen, A., Gallo, D., Pedersen, J., Biggar, R., Larsen, Olav, Dias, F. & Aaby, P., 4 May 1998, In: International Journal of Cancer. 76, 3, p. 293-298

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    3-Hydroxylysine, a potential marker for studying radical-induced protein oxidation

    Morin, B., Bubb, W. A., Davies, Michael J., Dean, R. T. & Fu, S., Nov 1998, In: Chemical Research in Toxicology. 11, 11, p. 1265-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage

    Morin, B., Davies, Michael J. & Dean, R. T., 15 Mar 1998, In: Biochemical Journal. 330 ( Pt 3), p. 1059-67 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Piskesmæld/whiplash: undersøgelse/behandling og opfølgning

    Mortensen, J. & Lønnberg, F., 1998, In: Maanedsskrift for Praktisk Laegegerning. 76, p. 255-262

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Padders vand- og saltbalance

    Møbjerg, Nadja, Sørensen, J. B., Jensen, Lars Jørn, Jespersen, Å., Willumsen, N. & Larsen, Erik Hviid, 1998, In: Naturens Verden. 5, p. 173-187 15 p.

    Research output: Contribution to journalJournal articleCommunication

  49. Published

    DNA damage in isolated rat hepatocytes exposed to C.I. pigment orange 5 and C.I. pigment yellow 12 by the alkaline comet assay

    Møller, P., Wallin, H., Grunnet, N., Risom, L. & Knudsen, Lisbeth E., 1998, In: Birth Defects Research. 18, 1, p. 9-16 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Distal small bowel hormones: Correlation with fasting antroduodenal motility and gastric emptying

    Naslund, E., Gryback, P., Backman, L., Jacobsson, H., Holst, Jens Juul, Theodorsson, E. & Hellstrom, P. M., 1998, In: Dig. Dis. Sci.. 43, p. 945-952

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Importance of small bowel peptides for the improved glucose metabolism 20 years after jejunoileal bypass for obesity

    Naslund, E., Backman, L., Holst, Jens Juul, Theodorsson, E. & Hellstrom, P. M., 1998, In: Obes. Surg.. 8, p. 253-260

    Research output: Contribution to journalJournal articleResearchpeer-review