Department of Biomedical Sciences

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  1. Published

    ACE inhibition attenuates uremia-induced aortic valve thickening in a novel mouse model

    Simolin, M. A., Pedersen, T. X., Bro, S., Mäyränpää, M. I., Helske, S., Nielsen, L. B. & Kovanen, P. T., 2009, In: BMC Cardiovascular Disorders. 9, p. 10 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    ACTA, a fluorescent analogue of thapsigargin, is a potent inhibitor and a conformational probe of skeletal muscle Ca2+-ATPase

    Procida, Kristina, Caspersen, C., Kromann, H., Christensen, S. B. & Treiman, M., 1998, In: FEBS Letters. 439, 1-2, p. 127-32 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    ACTH secretion in rats induced by stimulation with serotonergic compounds

    Jørgensen, H., Knigge, Ulrich, Kjær, Andreas & Warberg, J., 1999, In: Journal of Neuroendocrinology. 11, p. 283-290

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    ACTIVATION OF TLR2 BY ADAMTS-5-MEDIATED DEGRADATION FRAGMENTS OF CARTILAGE EXPLANTS IS INHIBITED BY THE ANTI-ADAMTS-5 NANOBODY (R), M6495 [Meeting Absraxt]

    Sharma, N., Thudium, C., Karsdal, M., Bay-Jensen, A., Gantzel, T., Michaelis, M., Ladel, C., Werkmann, D. & Lindemann, S., 2019, In: Annals of the Rheumatic Diseases. 78, S2, p. 1489-1489 AB0047.

    Research output: Contribution to journal › Conference abstract in journal › Research

  5. Published

    ADAM 12 alleviates the skeletal muscle 0pathology in mdx dystrophic mice

    Kronqvist, P. E., Kawaguchi, N., Albrechtsen, Reidar, Xu, X., Schrøder, H. D., Moghadas Zadeh, S. B., Nielsen, F. C., Frohlich, L. C., Engvall, E. & Wewer, Ulla M., 2002, In: American Journal of Pathology. 161, p. 1535-1540

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    ADAM 12 as a first-trimester maternal serum marker in screening for Down syndrome

    Laigaard, J., Spencer, K., Christiansen, M., Cowans, N. J., Larsen, S. O., Pedersen, B. N. & Wewer, Ulla M., 2006, In: Prenatal Diagnosis. 26, 10, p. 973-979 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    ADAM 12 may be used to reduce the false positive rate of first trimester combined screening for Down syndrome

    Christiansen, M., Pihl, K., Hedley, P. L., Gjerris, A., Lind, P. Ø., Larsen, S. O., Krebs, Lone & Larsen, T., Feb 2010, In: Prenatal Diagnosis. 30, 2, p. 110-4 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    ADAM 12 protease induces adipogenesis in transgenic mice.

    Kawaguchi, N., Xu, X., Tajima, R., Kronqvist, P., Sundberg, C., Loechel, F., Albrechtsen, Reidar & Wewer, Ulla M., 2002, In: American Journal of Pathology. 160, 5, p. 1895-903 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3.

    Loechel, F., Fox, J. W., Murphy, G., Albrechtsen, Reidar & Wewer, Ulla M., 2000, In: Biochemical and Biophysical Research Communications. 278, 3, p. 511-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    ADAM 12-S in first trimester: fetal gender, smoking and maternal age influence the maternal serum concentration

    Laigaard, J., Larsen, S. O., Pedersen, N. G., Hedley, P. L., Gjerris, A. C., Wøjdemann, K. R., Shalmi, A., Sundberg, K., Tabor, Ann & Christiansen, M., 2009, In: Prenatal Diagnosis. 29, 5, p. 525-7 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    ADAM12

    Kveiborg, Marie, Fröhlich, C., Albrechtsen, Reidar & Wewer, Ulla M., 29 Aug 2013, Handbook of Proteolytic Enzymes. Elsevier, Vol. 1. p. 1114-1122 9 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  12. Published

    ADAM12 alleviates the skeletal muscle pathology in mdx dystrophic mice

    Kronqvist, P., Kawaguchi, N., Albrechtsen, Reidar, Xu, X., Schrøder, H. D., Moghadaszadeh, B., Nielsen, Finn Cilius, Frohlich, C., Engvall, E. & Wewer, Ulla M., 1 Nov 2002, In: American Journal of Pathology. 161, 5, p. 1535-40 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    ADAM12 in first trimester maternal serum from pregnancies conceived by assisted reproduction techniques (ART)

    Laigaard, J., Pedersen, N. G., Larsen, S. O., Hedley, P. L., Wøjdemann, K., Gjerris, A. C., Shalmi, A., Sundberg, K., Tabor, Ann & Christiansen, M., 2009, In: Prenatal Diagnosis. 29, 6, p. 628-9 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    ADAM12 induces actin cytoskeleton and extracellular matrix reorganization during early adipocyte differentiation by regulating beta1 integrin function.

    Kawaguchi, N., Sundberg, C., Kveiborg, Marie, Moghadaszadeh, B., Asmar, M., Dietrich, N., Thodeti, C. K., Nielsen, F. C., Möller, P., Mercurio, A. M., Albrechtsen, Reidar & Wewer, Ulla M., 2003, In: Journal of Cell Science. 116, Pt 19, p. 3893-904 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    ADAM12 is a four-leafed clover: the excised prodomain remains bound to the mature enzyme.

    Wewer, Ulla M., Mörgelin, M., Holck, P., Jacobsen, J., Lydolph, M. C., Johnsen, A. H., Kveiborg, Marie & Albrechtsen, Reidar, 2006, In: Journal of Biological Chemistry. 281, 14, p. 9418-22 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins

    Frohlich, C., Klitgaard, M., Noer, J. B., Kotzsch, A., Nehammer, C., Kronqvist, P., Berthelsen, J., Blobel, C., Kveiborg, Marie, Albrechtsen, Reidar & Wewer, Ulla M., 15 May 2013, In: Biochemical Journal. 452, 1, p. 97-109 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    ADAM12 localizes with c-Src to actin-rich structures at the cell periphery and regulates Src kinase activity

    Stautz, D., Sanjay, A., Hansen, M. T., Albrechtsen, Reidar, Wewer, Ulla M. & Kveiborg, Marie, 2010, In: Experimental Cell Research. 316, 1, p. 55-67

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression

    Frohlich, C., Nehammer, C., Albrechtsen, Reidar, Kronqvist, P., Kveiborg, Marie, Sehara-Fujisawa, A., Mercurio, A. M. & Wewer, Ulla M., 29 Aug 2011, In: Molecular Cancer Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis and increased tumor growth

    Albrechtsen, Reidar, Kveiborg, Marie, Hansen, D. S., Vikeså, J., Noer, Julie Boertmann, Kotzsh, A., Nielsen, Finn Cilius, Wewer, Ulla M. & Frohlich, C., 15 Oct 2013, In: Journal of Cell Science. 126, 20, p. 4707-20 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    ADAM12-S stimulates bone growth in transgenic mice by modulating chondrocyte proliferation and maturation.

    Kveiborg, Marie, Albrechtsen, Reidar, Rudkjaer, L., Wen, G., Damgaard-Pedersen, K. & Wewer, Ulla M., 2006, In: Journal of Bone and Mineral Research. 21, 8, p. 1288-96 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.

    Thodeti, C. K., Frohlich, C., Nielsen, C. K., Takada, Y., Fässler, R., Albrechtsen, Reidar & Wewer, Ulla M., 2005, In: FEBS Letters. 579, 25, p. 5589-95 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA.

    Thodeti, C. K., Albrechtsen, Reidar, Grauslund, M., Asmar, M., Larsson, C., Takada, Y., Mercurio, A. M., Couchman, John Robert & Wewer, Ulla M., 2002, In: Journal of Biological Chemistry. 278, 11, p. 9576-84 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    ADAM12: a novel first-trimester maternal serum marker for Down syndrome.

    Laigaard, J., Sørensen, T., Fröhlich, C., Pedersen, B. N., Christiansen, M., Schiøtt, K., Uldbjerg, N., Albrechtsen, Reidar, Clausen, H. V., Ottesen, B. & Wewer, Ulla M., 2003, In: Prenatal Diagnosis. 23, 13, p. 1086-91 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    ADAMTS13--aktör och markör vid trombotisk mikroangiopati.

    Goetze, Jens P. , Lindblom, A., Björk, P., Strandberg, K., Manea, M., Hillarp, A. & Nielsen, L. B., 2008, In: Lakartidningen. 105, 15, p. 1092-5 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinoma

    Porter, S., Span, P. N., Sweep, F. C. G. J., Tjan-Heijnen, V. C. G., Pennington, C. J., Pedersen, T. X., Johnsen, M., Lund, L. R., Rømer, J. & Edwards, D. R., 2006, In: International Journal of Cancer. 118, 5, p. 1241-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations

    Graae, A-S., Grarup, N., Ribel-Madsen, R., Lystbæk, S. H., Boesgaard, T., Staiger, H., Fritsche, A., Wellner, N., Sulek, K., Kjølby, M. F., Backe, M. B., Chubanava, S., Prats, C., Serup, A. K. L., Birk, J. B., Dubail, J., Gillberg, L., Vienberg, S. G., Nykjær, A., Kiens, B. & 10 others, Wojtaszewski, Jørgen F P, Larsen, Steen, Apte, S. S., Häring, H., Vaag, A., Zethelius, B., Pedersen, Oluf Borbye, Treebak, Jonas Thue, Hansen, Torben & Holst, Birgitte, 2019, In: Diabetes. 68, 3, p. 502-514

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    ADD1/SREBP1c activates the PGC1-alpha promoter in brown adipocytes

    Hao, Q., Hansen, Jacob B., Petersen, R. K., Hallenborg, P., Jørgensen, C., Cinti, S., Larsen, P. J., Steffensen, K. R., Wang, H., Collins, S., Wang, J., Gustafsson, J., Madsen, L. & Kristiansen, Karsten, 2010, In: BBA General Subjects. 1801, 4, p. 421-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects

    Andersen, G., Burgdorf, K. S., Sparsø, T., Borch-Johnsen, K., Jørgensen, T., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 5, p. 1427-32 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    AKAP 18 a and g have opposing effects on insulin release in INS 1E cells

    Nielsen, Jens Høiriis, Lee, Y. C. & Thams, P. G., 2010, In: FEBS Letter. 584, p. 81-85

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    AKAP 18 alpha and gamma have opposing effects on insulin release in INS-1E cells

    Josefsen, K., Lee, Y. C., Thams, P., Efendic, S. & Nielsen, J. H., Jan 2010, In: FEBS Letters. 584, 1, p. 81-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    AMACR is not applicable as a diagnostic tool in hepatocellular carcinoma

    Willemoe, G. L. & Vainer, B., 1 Feb 2010, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 118, 2, p. 85-90 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    AMP-activated protein kinase - A universal regulator of autophagy?

    Hoyer-Hansen, M. & Jaattela, Marja, 2007, In: Autophagy. 3, 4, p. 381-383 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    AMP-activated protein kinase downregulates Kv7.1 cell surface expression

    Andersen, M. N., Krzystanek, K., Jespersen, Thomas, Olesen, Søren-Peter & Rasmussen, Hanne Borger, 2012, In: Traffic. 13, 1, p. 143-56 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    AMPK alpha1 activation is required for stimulation of glucose uptake by twitch contraction, but not by H2O2, in mouse skeletal muscle

    Jensen, Thomas Elbenhardt, Schjerling, Peter, Viollet, B., Wojtaszewski, Jørgen F P & Richter, Erik A., 2008, In: PLoS ONE. 3, 5, 9 p., e2102.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice

    Raun, Steffen Henning, Ali, Mona Sadek, Han, X., Henriquez-Olguín, Carlos, Pham, Tang Cam Phung, Knudsen, Jonas Roland, Willemsen, A. C. H., Larsen, S., Jensen, Thomas Elbenhardt, Langen, R. & Sylow, Lykke, 7 Jun 2022, bioRxiv, 37 p.

    Research output: Working paper › Preprint › Research

  36. Published

    AMPK: A regulator of ion channels

    Andersen, M. N. & Rasmussen, Hanne Borger, 2012, In: Communicative & Integrative Biology. 5, p. 480-484

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    AMPKγ3 Controls Muscle Glucose Uptake in Recovery From Exercise to Recapture Energy Stores

    Kido, K., Eskesen, N. O., Henriksen, Nicolai Stevns, Onslev, Johan Dejgaard, Kristensen, Jonas Møller, Larsen, Magnus Romme, Hingst, J. R., Knudsen, Jonas Roland, Birk, Jesper Bratz, Andersen, Nicoline Resen, Jensen, Thomas Elbenhardt, Pehmoller, C., Wojtaszewski, Jørgen F P & Kjøbsted, Rasmus, 2023, In: Diabetes. 72, 10, p. 1397-1408 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    ANP and BNP in atrial fibrillation before and after cardioversion - and their relationship to cardiac volume and function

    Therkelsen, S. K., Groenning, B. A., Kjær, Andreas, Svendsen, J. H. & Jensen, G. B., 2008, In: International Journal of Cardiology. 127, 3, p. 396-399 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    ANP and BNP in atrial fibrillation before and after cardioversion--and their relationship to cardiac volume and function

    Therkelsen, S. K., Groenning, B. A., Kjær, Andreas, Svendsen, Jesper Hastrup & Boje Jensen, G., 2007, In: International Journal of Cardiology. 127, 3, p. 396-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    ASSOCIATION BETWEEN LEFT ATRIAL STRAIN AND SUBCLINICAL ATRIAL FIBRILLATION IN PATIENTS WITH CRYPTOGENIC STROKE: THE SURPRISE ECHO SUBSTUDY

    Olsen, F. J., Christensen, L. M., Krieger, D. W., Højberg, S., Høst, N. B., Karlsen, F. M., Gislason, Gunnar Hilmar, Svendsen, Jesper Hastrup, Christensen, Hanne Krarup & Biering-Sørensen, Tor, 1 Mar 2019, In: Journal of the American College of Cardiology. 73, 9 Supp. 1, p. 1621 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  41. Published

    AT(1) receptor Gαq protein-independent signalling transcriptionally activates only a few genes directly, but robustly potentiates gene regulation from the β2-adrenergic receptor

    Christensen, G. L., Knudsen, S., Schneider, M., Aplin, M., Gammeltoft, S., Sheikh, S. P. & Hansen, J. L., 1 Jan 2011, In: Molecular and Cellular Endocrinology. 331, 1, p. 49-56 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    ATP economy of force maintenance in human tibialis anterior muscle.

    Nakagawa, Y., Ratkevicius, A., Mizuno, M. & Quistorff, B., 2005, In: Medicine and Science in Sports and Exercise. 37, 6, p. 937-43 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    AUTOIMMUNITY AGAINST COLLAGEN IN RHEUMATOID ARTHRITIS (RA): SERUM LEVELS OF IgG AGAINST DENATURED TYPE II COLLAGEN SIGNIFICANTLY ELEVATED IN RA

    Drobinski, P., Aighobahi, E., Bay-Jensen, A. C. & Karsdal, M., 2021, In: Annals of the Rheumatic Diseases. 80, p. 468-468 POS0473.

    Research output: Contribution to journal › Conference abstract in journal › Research

  44. Published

    Aberrant accumulation of the diabetes autoantigen GAD65 in Golgi membranes in conditions of ER stress and autoimmunity

    Phelps, E. A., Cianciaruso, C., Michael, I. P., Pasquier, M., Kanaani, J., Nano, R., Lavallard, V., Billestrup, Nils, Hubbell, J. A. & Baekkeskov, S., Sep 2016, In: Diabetes. 65, 9, p. 2686-2699

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Aberrant expression of miR-218 and miR-204 in human mesial temporal lobe epilepsy and hippocampal sclerosis-Convergence on axonal guidance

    Kaalund, S. S., Venø, M. T., Bak, M., Møller, R. S., Laursen, H., Madsen, F., Broholm, H., Quistorff, B., Uldall, P., Tommerup, Niels, Kauppinen, S., Sabers, A., Fluiter, K., Møller, L. B., Nossent, Anne Yaël, Silahtaroglu, Asli, Kjems, J., Aronica, E. & Tümer, Asuman Zeynep, Dec 2014, In: Epilepsia. 55, 12, p. 2017-2027 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Aberrant myonuclear domains and impaired myofiber contractility despite marked hypertrophy in MYMK-related, Carey-Fineman-Ziter Syndrome

    Dugdale, H. F., Levy, Y., Jungbluth, H., Oldfors, A. & Ochala, Julien, 2024, In: Acta Neuropathologica Communications. 12, 1, 80.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Aberrant sinus node firing during beta-adrenergic stimulation leads to cardiac arrhythmias in diabetic mice

    Lubberding, Anniek Frederike, Pereira, L., Xue, J., Gottlieb, Lisa Amalie, Matchkov, V. V., Gomez, A. M. & Thomsen, Morten Bækgaard, 2020, In: Acta Physiologica. 229, 1, 12 p., e13444.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting- and ghrelin-mediated food intake

    de Guia, R. M., Hassing, Anna Skab, Ma, Tao, Plucinska, Kaja, Holst, Birgitte, Gerhart-Hines, Zach, Emanuelli, Brice & Treebak, Jonas Thue, 2021, In: F A S E B Journal. 35, 5, e21450.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Abnormal bone collagen morphology and decreased bone strength in growth hormone-deficient rats.

    Lange, M., Qvortrup, Klaus, Svendsen, Ole Lander, Flyvbjerg, A., Nowak, J., Petersen, M. M., Ølgaard, Klaus & Feldt-Rasmussen, Ulla, 2004, In: Bone. 35, 1, p. 178-85 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Abnormal electrograms during sinus rhythm for VT ablation: Beware of Fata Morganas

    Hermans, B. J. M. & Dr Linz, Dominik Karl, 2021, In: Journal of Cardiovascular Electrophysiology. 32, 2, p. 389-390

    Research output: Contribution to journal › Editorial › Research › peer-review

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