Department of Biomedical Sciences

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  1. Published

    The resolution revolution in cryoEM requires high-quality sample preparation: a rapid pipeline to a high-resolution map of yeast fatty acid synthase

    Joppe, M., D'Imprima, E., Salustros, N., Paithankar, K. S., Vonck, J., Grininger, M. & Kuehlbrandt, W., 2020, In: IUCrJ. 7, p. 220-227 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The response of mitochondrial respiration and quantity in skeletal muscle and adipose tissue to exercise in humans with prediabetes

    Szczerbinski, L., Taylor, M. A., Puchta, U., Konopka, P., Paszko, A., Citko, A., Szczerbinski, K., Goscik, J., Gorska, M., Larsen, Steen & Kretowski, A., 2021, In: Cells. 10, 11, 3013.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The retina: oxidative stress and diabetes

    van Reyk, D. M., Gillies, M. C. & Davies, Michael J., 2003, In: Redox Report (Online). 8, 4, p. 187-92 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The retinoblastoma-histone deacetylase 3 complex inhibits PPARgamma and adipocyte differentiation

    Fajas, L., Egler, V., Reiter, R., Hansen, Jacob B., Kristiansen, K., Debril, M., Miard, S. & Auwerx, J., 2002, In: Developmental Cell. 3, 6, p. 903-10 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain

    Leone, D. P., Srinivasan, K., Brakebusch, Cord Herbert & McConnell, S. K., 2010, In: Developmental Neurobiology. 70, 9, p. 659-78 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The right modality for the right pulmonary vein shape in ablation for atrial fibrillation

    Isaksen, Jonas L., Manninger, M. & Dr Linz, Dominik Karl, 2023, In: Journal of Interventional Cardiac Electrophysiology. 66, p. 827–828

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  7. Published

    The rise of statins in Denmark: Making the case for a localized approach to the routinization of pharmaceutical prevention of cardiovascular disease

    Lau, Sofie Rosenlund, Andersen, John Sahl, Dela, Flemming & Oxlund, Bjarke, 2019, In: BioSocieties. 14, 2, p. 228-250 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The risk of asthma is increased among women with polycystic ovary syndrome: a twin study

    Zierau, L., Meteran, H., Backer, Vibeke, Lindenberg, S., Skytthe, A. & Thomsen, Simon Francis, Sep 2019, In: ERJ Open Research. 5, 3, 7 p., 00018-2018.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The road to biologics in patients with hidradenitis suppurativa: a nationwide drug utilization study

    Ring, H. C., Yao, Y., Maul, J. T., Ingram, J. R., Frew, J. W., Thorsen, Jonathan Jan Ilve, Nielsen, M. L., Wu, J. J., Thyssen, Jacob Pontoppidan, Thomsen, Simon Francis & Egeberg, Alexander, 2022, In: British Journal of Dermatology. 187, 4, p. 523-530 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The role of CAV3 in long-QT syndrome: clinical and functional assessment of a caveolin-3/Kv11.1 double heterozygote versus caveolin-3 single heterozygote

    Hedley, P. L., Kanters, Jørgen K., Dembic, M., Jespersen, Thomas, Skibsbye, L., Aidt, F. H., Eschen, O., Graff, C., Behr, E. R., Schlamowitz, S., Corfield, V., McKenna, W. J. & Christiansen, M., Oct 2013, In: Circulation: Cardiovascular Genetics. 6, 5, p. 452-61 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The role of GH in adipose tissue: Lessons from adipose-specific GH receptor gene-disrupted mice

    List, E. O., Berryman, D. E., Funk, K., Gosney, E. S., Jara, A., Kelder, B., Wang, X., Kutz, L., Troike, K., Lozier, N., Mikula, V., Lubbers, E. R., Zhang, H., Vesel, C., Junnila, R. K., Frank, S. J., Masternak, M. M., Bartke, A. & Kopchick, J. J., 7 Mar 2013, In: Molecular Endocrinology. 27, 3, p. 524-535 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The role of GH receptor tyrosine phosphorylation in Stat5 activation

    Hansen, J. A., Hansen, Lars Hestbjerg, Wang, X., Kopchick, J. J., Gouilleux, F., Groner, B., Møldrup, A., Galsgaard, E. D., Nielsen, Jens Høiriis & Billestrup, Nils, Jun 1997, In: Journal of Molecular Endocrinology. 18, 3, p. 213-21 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The role of GLP-1 in postprandial glucose metabolism after bariatric surgery: a narrative review of human GLP-1 receptor antagonist studies

    Hindsø, M., Svane, M. S., Hedbäck, N., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2021, In: Surgery for Obesity and Related Diseases. 17, 7, p. 1383-1391

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    The role of GLP-1 in the postprandial effects of acarbose in type 2 diabetes

    Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Hansen, L. S., Hansen, N. L., Stensen, S., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: European Journal of Endocrinology. 184, 3, p. 387-398 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The role of NCAM signaling in the pancreatic beta-cell

    Grunnet, L. G., Storling, J., Heding, P., Li, S., Berezin, V., Saldeen, J., Billestrup, N., Bock, E. & Mandrup-Poulsen, Thomas, 2008, In: FEBS Journal. 275, Suppl. 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.

    Hansen, L. T., Lundin, C., Spang-Thomsen, M., Petersen, L. N. & Helleday, T., 2003, In: International Journal of Cancer. 105, 4, p. 472-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The role of RNA oxidation in islet dysfunction in Type 2 diabetes

    Sileikaite, I., Davies, Michael J., Mandrup-Poulsen, Thomas & Hawkins, Clare Louise, 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1 , p. S37-S38

    Research output: Contribution to journal › Conference abstract in journal › Research

  18. E-pub ahead of print

    The role of aetiology in cardiac manifestations of chronic kidney disease: the CPH-CKD ECHO study

    Christensen, J., Landler, N. E., Olsen, F. J., Sørensen, I. M. H., Bjergfelt, S. S., Ballegaard, E. L. F., Feldt-Rasmussen, Bo, Hansen, Ditte, Kamper, A. L., Christoffersen, Christina, Bro, S. & Biering-Sørensen, Tor, 2024, (E-pub ahead of print) In: International Journal of Cardiovascular Imaging.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The role of bone SPECT/CT in the evaluation of lumbar spinal fusion with metallic fixation devices

    Damgaard, Morten, Nimb, L. & Madsen, J. L., 2010, In: Clinical Nuclear Medicine. 35, 4, p. 234-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The role of cellular senescence in profibrillatory atrial remodelling associated with cardiac pathology

    Mehdizadeh, M., Naud, P., Abu-Taha, I. H., Hiram, R., Xiong, F., Xiao, J., Saljic, Arnela, Kamler, M., Vuong-Robillard, N., Thorin, E., Ferbeyre, G., Tardif, J. C., Sirois, M. G., Tanguay, J. F., Dobrev, D. & Nattel, S., 2024, In: Cardiovascular Research. 120, 5, p. 506-518 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The role of common genetic variants in atrial fibrillation

    Paludan-Müller, Christian, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2016, In: Journal of Electrocardiology. 49, 6, p. 864-870

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 309, 5, p. R544-51 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The role of empagliflozin-induced metabolic changes for cardiac function in patients with type 2 diabetes. A randomized cross-over magnetic resonance imaging study with insulin as comparator

    Thirumathyam, R., Richter, Erik A., van Hall, Gerrit, Holst, Jens Juul, Fenger, M., Goetze, Jens P. , Dixen, Ulrik, Vejlstrup, N., Madsbad, Sten, Madsen, Per & Jørgensen, N. B., 2024, In: Cardiovascular Diabetology. 23, 1, p. 1-13 13.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The role of endogenous GIP and GLP-1 in postprandial bone homeostasis

    Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Bergmann, N. C., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Bone. 140, 7 p., 115553.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The role of fibrosis in cardiomyopathies: An opportunity to develop novel biomarkers of disease activity

    Angeli, Elisavet, Jordan, M., Otto, M., Stojanović, S. D., Karsdal, M., Bauersachs, J., Thum, T., Fiedler, J. & Genovese, F., 2024, In: Matrix Biology. 128, p. 65-78

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    The role of full-length apoE in clearance of Gram-negative bacteria and their endotoxins

    Petruk, G., Elven, M., Hartman, E., Davoudi, M., Schmidtchen, A., Puthia, M. & Petrlova, J., 2021, In: Journal of Lipid Research. 62, 14 p., 100086.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The role of glucagon in the acute therapeutic effects of SGLT2 inhibition

    Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes. 69, 12, p. 2619-2629 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The role of growth hormone and prolactin in beta cell growth and regeneration

    Nielsen, Jens Høiriis, Møldrup, A., Billestrup, Nils, Petersen, E. D., Allevato, G. & Stahl, M., 1992, Pancreatic islet cell regeneration and growth. Vol. 321. p. 9-17; discussion 19-20 (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  29. Published

    The role of incretins on insulin function and glucose homeostasis

    Holst, Jens Juul, Gasbjerg, Lærke Smidt & Rosenkilde, Mette, 2021, In: Endocrinology. 162, 7, 10 p., bqab065.

    Research output: Contribution to journal › Review › Research › peer-review

  30. Published

    The role of leptin in fetal growth during pre-eclampsia

    de Knegt, V. E., Hedley, P. L., Kanters, Jørgen K., Thagaard, I. N., Krebs, Lone, Christiansen, M. & Lausten-Thomsen, U., 1 May 2021, In: International Journal of Molecular Sciences. 22, 9, 16 p., 4569.

    Research output: Contribution to journal › Review › Research › peer-review

  31. Published

    The role of leptin in human lipid and glucose metabolism: the effects of acute recombinant human leptin infusion in young healthy males

    Wolsk, E., Mygind, H., Grøndahl, T. S., Pedersen, Bente Klarlund & van Hall, Gerrit, 2011, In: American Journal of Clinical Nutrition. 94, 6, p. 1533-44 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The role of local voltage potentials in outflow tract ectopy

    Bloch Thomsen, P. E., Johannessen, A., Jons, C., Hansen, T. F., Kanters, Jørgen K., Haarbo, J., Hansen, J., Christiansen, L. K., Sogaard, P., Saermark, K. & Antzelevitch, C., 1 Jun 2010, In: Europace. 12, 6, p. 850-60 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The role of mismatch repair in small-cell lung cancer cells

    Hansen, L. T., Thykjaer, T., Ørntoft, T. F., Rasmussen, L. J., Keller, P., Spang-Thomsen, M., Edmonston, T. B., Schmutte, C., Fishel, R. & Petersen, L. N., 2003, In: European Journal of Cancer. 39, 10, p. 1456-67 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The role of motor protein dynein on Kv7 channel trafficking in vascular smooth muscle

    van der Horst, Jennifer, 2022, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen. 186 p.

    Research output: Book/Report › Ph.D. thesis

  35. Published

    The role of phosphorylation in calmodulin-mediated gating of human AQP0

    Kreida, S., Roche, J. V., Missel, Julie Winkel, Al-Jubair, T., Hagströmer, C. J., Wittenbecher, V., Linse, S., Gourdon, Pontus Emanuel & Törnroth-Horsefield, S., 2024, In: The Biochemical journal. 481, 1, p. 17-32 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The role of postprandial releases of insulin and incretin hormones in meal-induced satiety - effect of obesity and weight reduction

    Verdich, C., Toubro, S., Buemann, B. & Holst, Jens Juul, 2001, In: International Journal of Obesity. 25, p. 1206-1214

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The role of sarcomere gene mutations in patients with idiopathic dilated cardiomyopathy

    Møller, D. V., Andersen, P. S., Hedley, P., Ersbøll, M. K., Bundgård, Henning, Moolman-Smook, J., Christiansen, M. & Køber, Lars Valeur, 2009, In: European Journal of Human Genetics. 17, 10, p. 1241-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The role of subsite 2 of the Trichoderma reesei β-mannanase TrMan5A in hydrolysis and transglycosylation

    Rosengren, A., Hägglund, Per Mårten, Anderson, L., Pavon-Orozco, P., Peterson-Wulff, R., Nerinckx, W. & Stålbrand, H., 1 May 2012, In: Biocatalysis and Biotransformation. 30, 3, p. 338-352 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The role of the incretins in the postprandial bone remodelling

    Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S221-S221 449.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  40. Published

    The role of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) in the induction of mitochondrial dysfunction in macrophages

    Love, D. T., Guo, C., Nikelshparg, E. I., Brazhe, N. A., Sosnovtseva, Olga & Hawkins, Clare Louise, 2020, In: Redox Biology. 36, 12 p., 101602.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome

    Winkel, B. G., Yuan, L., Olesen, Morten Steen Salling, Sadjadieh, G., Wang, Y., Risgaard, B., Jabbari, R., Haunsø, Stig, Holst, A. G., Hollegaard, M. V., Tfelt-Hansen, J. & Jespersen, Thomas, Jun 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 6, p. 1241-1249 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The role of traditional cardiovascular risk factors among patients with rheumatoid arthritis

    Brady, S. R. E., de Courten, B., Reid, C. M., Cicuttini, F. M., de Courten, M. & Liew, D., 1 Jan 2009, In: Journal of Rheumatology. 36, 1, p. 34-40 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The role of vitamin C in epigenetic cancer therapy

    Mikkelsen, Stine Ulrik, Gillberg, Linn, Lykkesfeldt, Jens & Grønbæk, Kirsten, 2021, In: Free Radical Biology and Medicine. 170, p. 179-193 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The role of water coordination in the pH-dependent gating of hAQP10

    Truelsen, S. F., Missel, Julie Winkel, Gotfryd, K., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel, Lindorff-Larsen, Kresten & Hélix-Nielsen, C., 2022, In: B B A - Biomembranes. 1864, 1, 13 p., 183809.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The role og K+ and C1- channels in salivary secretion

    Stummann, T. C., Poulsen, J. H., Hay-Schmidt, Anders, Grunnet, Morten, Klærke, Dan Arne, Olesen, Søren-Peter & Jørgensen, N. K., 2003, In: Pflügers Archiv: European Journal of Physiology. 446, p. 78-87

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    The rs1800629 polymorphism in the TNF gene interacts with physical activity on the changes in C-reactive protein levels in the Finnish Diabetes Prevention Study

    Kilpeläinen, Tuomas O., Laaksonen, D. E., Lakka, T. A., Herder, C., Koenig, W., Lindström, J., Eriksson, J. G., Uusitupa, M., Kolb, H., Laakso, M., Tuomilehto, J. & Finnish Diabetes Prevention Study, F. D. P. S., Nov 2010, In: Experimental and Clinical Endocrinology and Diabetes. 118, 10, p. 757-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    The rs9939609 FTO gene in relation to all-cause mortality in a prospective cohort study of Danish men

    Zimmermann, E., Jess, T., Kring, S., Berentzen, T., Holst, C., Hansen, T., Pedersen, O., Astrup, A. & Sørensen, Thorkild I.A., 2008, In: International Journal of Obesity. 32, Suppl. 1, p. S187 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  48. Published

    The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

    Helgadottir, A., Thorleifsson, G., Magnusson, K. P., Grétarsdottir, S., Steinthorsdottir, V., Manolescu, A., Jones, G. T., Rinkel, G. J. E., Blankensteijn, J. D., Ronkainen, A., Jääskeläinen, J. E., Kyo, Y., Lenk, G. M., Sakalihasan, N., Kostulas, K., Gottsäter, A., Flex, A., Stefansson, H., Hansen, T., Andersen, G. & 48 others, Weinsheimer, S., Borch-Johnsen, K., Jørgensen, T., Shah, S. H., Quyyumi, A. A., Granger, C. B., Reilly, M. P., Austin, H., Levey, A. I., Vaccarino, V., Palsdottir, E., Walters, G. B., Jonsdottir, T., Snorradottir, S., Magnusdottir, D., Gudmundsson, G., Ferrell, R. E., Sveinbjornsdottir, S., Hernesniemi, J., Niemelä, M., Limet, R., Andersen, K., Sigurdsson, G., Benediktsson, R., Verhoeven, E. L. G., Teijink, J. A. W., Grobbee, D. E., Rader, D. J., Collier, D. A., Pedersen, Oluf Borbye, Pola, R., Hillert, J., Lindblad, B., Valdimarsson, E. M., Magnadottir, H. B., Wijmenga, C., Tromp, G., Baas, A. F., Ruigrok, Y. M., van Rij, A. M., Kuivaniemi, H., Powell, J. T., Matthiasson, S. E., Gulcher, J. R., Thorgeirsson, G., Kong, A., Thorsteinsdottir, U. & Stefansson, K., 2008, In: Nature Genetics. 40, 2, p. 217-24 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The serum metabolite response to diet intervention with probiotic acidified milk in irritable bowel syndrome patients is indistinguishable from that of non-probiotic acidified milk by 1H NMR-based metabonomic analysis

    Pedersen, S. M., Nielsen, N. C., Andersen, H. J., Olsson, J., Simrén, M., Ohman, L., Svensson, U., Malmendal, A. & Bertram, H. C. S., 2010, In: Nutrients. 2, 11, p. 1141-55 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    The significance of left ventricular ejection time in heart failure with reduced ejection fraction

    Alhakak, Alia Saed, Teerlink, J. R., Lindenfeld, J., Boehm, M., Rosano, G. M. C. & Biering-Sørensen, Tor, 2021, In: European Journal of Heart Failure. 23, 4, p. 541-551

    Research output: Contribution to journal › Review › Research › peer-review

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