Department of Biomedical Sciences

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  1. Published

    The long-acting GLP-1 derivative NN2211 ameliorates glycemia and increases beta-cell mass in diabetic mice.

    Rolin, B., Larsen, M. O., Gotfredsen, C. F., Deacon, Carolyn F., Carr, R. D., Wilken, M. & Knudsen, L. B., 2002, In: American Journal of Physiology: Endocrinology and Metabolism. 283, 4, p. E745-52

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The loss of Sirt1 in mouse pancreatic beta cells impairs insulin secretion by disrupting glucose sensing

    Luu, L., Dai, F. F., Prentice, K. J., Huang, X., Hardy, A. B., Hansen, J. B., Liu, Y., Joseph, J. W. & Wheeler, M. B., Sep 2013, In: Diabetologia. 56, 9, p. 2010-20 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The lysine deacetylase inhibitor givinostat inhibits ß-cell IL-1ß induced IL-1ß transcription and processing

    Dahllöf, M. S., Christensen, D. P., Lundh, M., Dinarello, C. A., Mascagni, P., Grunnet, L. G. & Mandrup-Poulsen, Thomas, 1 Nov 2012, In: Islets. 4, 6, p. 417-22 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The mRNA expression profile of metabolic genes relative to MHC isoform pattern in human skeletal muscles

    Plomgaard, Peter Stendahl, Penkowa, M., Leick, L., Pedersen, Bente Klarlund, Saltin, B. & Pilegaard, Henriette, 2006, In: Journal of Applied Physiology. 101, 3, p. 817-25 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The major glucagon-like peptide-1 metabolite, GLP-1-(9-36)-amide, does not affect glucose or insulin levels in mice.

    Rolin, B., Deacon, Carolyn F., Carr, R. D. & Ahrén, B., 2004, In: European Journal of Pharmacology. 494, 2-3, p. 283-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The mechanism of gastrin release in cysteamine-induced duodenal ulcer

    Poulsen, Steen Seier, Aug 1982, In: Scandinavian Journal of Gastroenterology. 17, 5, p. 609-12 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo

    Panaro, B. L., Tough, I. R., Engelstoft, M. S., Matthews, R. T., Digby, G. J., Møller, C. L., Svendsen, B., Gribble, F., Reimann, F., Holst, Jens Juul, Holst, Birgitte, Schwartz, Thue W., Cox, H. M. & Cone, R. D., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 1018-29 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The membrane fraction of homogenized rat kidney contains an enzyme that releases epidermal growth factor from the kidney membranes

    Nexø, E. & Poulsen, Steen Seier, 8 Jul 1991, In: BBA General Subjects. 1074, 2, p. 284-88 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits

    Voight, B. F., Kang, H. M., Ding, J., Palmer, C. D., Sidore, C., Chines, P. S., Burtt, N. P., Fuchsberger, C., Li, Y., Erdmann, J., Frayling, T. M., Heid, I. M., Jackson, A. U., Johnson, T., Oskari Kilpeläinen, T., Lindgren, C. M., Morris, A. P., Prokopenko, I., Randall, J. C., Saxena, R. & 29 others, Soranzo, N., Speliotes, E. K., Teslovich, T. M., Wheeler, E., Maguire, J., Parkin, M., Potter, S., Rayner, N. W., Robertson, N., Stirrups, K., Winckler, W., Sanna, S., Mulas, A., Nagaraja, R., Cucca, F., Barroso, I., Deloukas, P., Loos, R. J. F., Kathiresan, S., Munroe, P. B., Newton-Cheh, C., Pfeufer, A., Samani, N. J., Schunkert, H., Hirschhorn, J. N., Altshuler, D., McCarthy, M. I., Abecasis, G. R. & Boehnke, M., 2012, In: P L o S Genetics (Online). 8, 8, p. e1002793

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The metabolic profile of long-lived Drosophila melanogaster

    Sarup, P. M., Pedersen, S. M. M., Nielsen, N. C., Malmendal, A. & Loeschcke, V., 2012, In: P L o S One. 7, 10

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The metabolic signature of cardiovascular disease and arterial calcification in patients with chronic kidney disease

    Sørensen, I. M., Bisgaard, Line, Bjergfelt, S. S., Ballegaard, E. L., Biering-Sørensen, Tor, Landler, N. E., Pedersen, T. X., Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Bro, S. & Christoffersen, Christina, 2022, In: Atherosclerosis. 350, p. 109-118 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The metabolic syndrome is frequent in children and adolescents with type 1 diabetes compared to healthy controls

    Mork, F. B., Madsen, J. O. B., Pilgaard, Kasper Ascanius, Jensen, Andreas Kryger, Klakk, H., Tarp, J., Bugge, A., Heidemann, M., van Hall, Gerrit, Pociot, Flemming, Wedderkopp, N. & Johannesen, Jesper, 2022, In: Pediatric Diabetes. 23, 7, p. 1064-1072 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes

    Zander, M., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 369-74 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes

    Zander, M., Madsbad, S., Deacon, Carolyn F. & Holst, Jens Juul, 2006, In: Diabetologia. 49, 2, p. 369-374 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The microtubule network enables Src kinase interaction with the Na,K-ATPase to generate Ca2+ flashes in smooth muscle cells

    Rognant, Salomé, Kravtsova, V. V., Bouzinova, E. V., Melnikova, E. V., Krivoi, I. I., Pierre, S. V., Aalkjær, Christian, Jepps, Thomas Andrew Qvistgaard & Matchkov, V. V., 2022, In: Frontiers in Physiology. 13, 14 p., 1007340.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The microvascular volume of the achilles tendon is increased in patients with tendinopathy at rest and after a 1-hour treadmill run

    Pingel, Jessica, Harrison, Adrian Paul, Simonsen, L., Suetta, Charlotte, Bülow, J. & Langberg, Henning, 2013, In: American Journal of Sports Medicine. 41, 10, p. 2400-2408 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load

    Hornbak, M., Banasik, Karina, Justesen, Johanne Marie, Krarup, N. T., Sandholt, C. H., Andersson, Åsa, Sandbaek, A., Lauritzen, T., Pisinger, C., Witte, D. R., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 6 Jan 2011, In: BMC Medical Genetics. 12, 1, p. 4 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The minor binding pocket: a major player in 7TM receptor activation

    Rosenkilde, Mette, Benned-Jensen, T., Frimurer, T. M. & Schwartz, Thue W., 2010, In: Trends in Pharmacological Sciences. 31, 12, p. 567-574 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The minor collagens in articular cartilage

    Luo, Y., Sinkeviciute, D., He, Y., Karsdal, M., Henrotin, Y., Mobasheri, A., Onnerfjord, P. & Bay-Jensen, A., 2017, In: Protein & Cell (Online). 8, 8, p. 560-572 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    The mitogenic effect of Gas6 on pancreatic beta cells is mediated via the receptor tyrosine kinase Axl

    Haase, T. N., Gustafsson, A., Nalla, A., Ringholm, L., Damm, Peter, Mathiesen, Elisabeth, Dahlback, B., Billestrup, Nils & Nielsen, Jens Høiriis, Sep 2014, In: Diabetologia. 57, 1 Suppl, p. S173-S174 408.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  21. Published

    The morphological growth patterns of colorectal liver metastases are prognostic for overall survival

    Nielsen, K., Rolff, H. C., Eefsen, R. L. & Vainer, B., 23 May 2014, In: Modern Pathology. 27, p. 1641-1648 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The muscle-specific protein phosphatase PP1G/R(GL)(G(M))is essential for activation of glycogen synthase by exercise

    Aschenbach, W. G., Suzuki, Y., Breeden, K., Prats Gavalda, Clara, Hirshman, M. F., Dufresne, S. D., Sakamoto, Kei, Vilardo, P. G., Steele, M., Kim, J. H., Jing, S. L., Goodyear, L. J. & DePaoli-Roach, A. A., 2001, In: Journal of Biological Chemistry. 276, 43, p. 39959-67 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The muscles work but the brain gets tired

    Secher, N. H., Quistorff, B. & Dalsgaard, M. K., 2006, In: Ugeskrift for læger. 168, 46, p. 4503-

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The myeloperoxidase-derived oxidant hypothiocyanous acid inhibits protein tyrosine phosphatases via oxidation of key cysteine residues

    Cook, N. L., Moeke, C. H., Fantoni, L. I., Pattison, D. I. & Davies, Michael J., 1 Jan 2016, In: Free Radical Biology & Medicine. 90, p. 195-205 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The nanostructure of myoendothelial junctions contributes to signal rectification between endothelial and vascular smooth muscle cells

    Brasen, J. C., Jacobsen, Jens Christian Brings & von Holstein-Rathlou, Niels-Henrik, 2012, In: P L o S One. 7, 4, p. e33632

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The natural GIP receptor mutation E345Q displays enhanced signalling and internaliation mimicking GIP receptor desensitisation: [Meeting Abstract}

    Gabe, M. B. N., 2019, In: Diabetologia. 62, Supl. 1/SI, p. S231-S231 471.

    Research output: Contribution to journal › Conference abstract in journal › Research

  27. Published

    The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

    Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The need to freeze—Dehydration during specimen preparation for electron microscopy collapses the endothelial glycocalyx regardless of fixation method

    Hempel, C., Kapishnikov, S., Perez-Berna, A. J., Werner, S., Guttmann, P., Pereiro, E., Qvortrup, Klaus & Andresen, T. L., 2020, In: Microcirculation. 27, 7, e12643.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The nephron-arterial network and its interactions

    Marsh, D. J., Postnov, D. D., Sosnovtseva, Olga & von Holstein-Rathlou, Niels-Henrik, 2019, In: American Journal of Physiology: Renal Physiology. 316, 5, p. F769-F784

    Research output: Contribution to journal › Review › Research › peer-review

  30. Published

    The newcomer in the integrin family: Integrin α9 in biology and cancer.

    Høye, A. M., Couchman, John Robert, Wewer, Ulla M., Yoneda, A. & Fukami, K., May 2012, In: Advances in Biological Regulation. 52, 2, p. 326-339

    Research output: Contribution to journal › Review › Research › peer-review

  31. Published

    The nicotinic alpha7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice overexpressing human amyloid-beta1-42

    Soderman, A., Spang-Thomsen, M., Hansen, H., Nielsen, E. O., Jensen, M. S., West, M. J. & Mikkelsen, J. D., 2008, In: Brain Research. 1227, p. 240-247 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE(-/-) mice

    Kim, C. H. J., Mitchell, J. B., Bursill, C. A., Sowers, A. L., Thetford, A., Cook, J. A., van Reyk, D. M. & Davies, Michael J., May 2015, In: Atherosclerosis. 240, 1, p. 234-241 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-Terminal β-hairpin and induces neutrophil migration as a selective CXCR2 agonist

    Berg, Christian, Wedemeyer, M. J., Melynis, M., Schlimgen, R. R., Hansen, L. H., Vabenø, J., Peterson, F. C., Volkman, B. F., Rosenkilde, Mette & Lüttichau, H. R., 2022, In: PLOS Pathogens. 18, 3, e1010355.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The novel C-terminal KCNQ1 mutation M520R alters protein trafficking.

    Schmitt, Nicole, Callø, Kirstine, Nielsen, N. H., Buschmann, M., Speckmann, E., Schulze-Bahr, E. & Schwarz, M., 2007, In: Biochemical and Biophysical Research Communications. 358, 1, p. 304-10 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The novel β3-adrenoceptor agonist mirabegron reduces carbachol-induced contractile activity in detrusor tissue from patients with bladder outflow obstruction with or without detrusor overactivity

    Svalø, J., Nordling, J., Bouchelouche, K., Andersson, K., Korstanje, C., Bouchelouche, P. & Svalø, J., 15 Jan 2013, In: European Journal of Pharmacology. 699, 1-3, p. 101-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The nude mouse as an in vivo model for human breast cancer invasion and metastasis

    Brünner, N., Boysen, B., Rømer, J. & Spang-Thomsen, M., 1993, In: Breast Cancer Research and Treatment. 24, 3, p. 257-64 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet ß cells in vivo and in vitro

    Lewis, E. C., Blaabjerg, L., Størling, Joachim, Ronn, S. G., Mascagni, P., Dinarello, C. A. & Mandrup-Poulsen, Thomas, May 2011, In: Molecular Medicine. 17, 5-6, p. 369-377 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The organization of the Golgi complex and microtubules in skeletal muscle is fiber type-dependent

    Ralston, E., Lu, Z. & Ploug, Thorkil, 15 Dec 1999, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 19, 24, p. 10694-705 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The origin of extracellular DNA in bacterial biofilm infections in vivo

    Alhede, M., Alhede, M., Qvortrup, Klaus, Kragh, K. N., Jensen, Peter Østrup, Stewart, P. S. & Bjarnsholt, Thomas, 2020, In: Pathogens and Disease. ftaa018.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The outcome of bone mineral density measurements on patients referred from general practice

    Iqbal, S. I., Mørch, L. S., Rosenzweig, M. & Dela, Flemming, 2005, In: Journal of Clinical Densitometry. 8, 2, p. 178-82 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    The p53 target Wig-1 regulates p53 mRNA stability through an AU-rich element

    Vilborg, A., Glahder, J. H., Wilhelm, M. T., Bersani, C., Corcoran, M., Mahmoudi, S., Rosenstierne, M., Grandér, D., Farnebo, M., Norrild, B. & Wiman, K. G., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 37, p. 15756-61 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The paradox of systemic vasodilatation and sympathetic nervous stimulation in space

    Norsk, P. & Christensen, N. J., 2009, In: Respiratory Physiology & Neurobiology. 169 Suppl 1, p. S26-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The pathogenesis of diabetes involves a defective amplication of the late phase insulin response to glucose by GIP - regardless of aetiology and phenotype

    Vilsbøll, T., Knop, F., Krarup, T., Johansen, A., Madsbad, S., Larsen, S., Hansen, T., Pedersen, O. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 4897-4903

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The pathogenesis of non-insulin dependent diabetes mellitus involves a defective expression of the GIP receptor.

    Holst, Jens Juul, Gromada, J. L. & Nauck, M. A., 1997, In: Diabetologia. 40, p. 984-986

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The pathogenicity of genetic variants previously associated with left ventricular non-compaction

    Abbasi, Y., Jabbari, J., Jabbari, R., Yang, R., Risgaard, B., Køber, Lars Valeur, Haunsø, Stig & Tfelt-Hansen, Jacob, 2016, In: Molecular Genetics & Genomic Medicine. 4, 2, p. 135-142

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    The pattern of distribution of laminin in neurogenic tumors, granular cell tumors, and nevi of the oral mucosa.

    Reibel, J., Wewer, Ulla M. & Albrechtsen, Reidar, 1985, In: Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology. 93, 2, p. 41-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    The perinatal health challenges of emerging and re-emerging infectious diseases: A narrative review

    Malange, V. N. E., Hedermann, G., Lausten-Thomsen, U., Hoffmann, S., Voldstedlund, M., cnj340, cnj340, Eltvedt, A. K., Jensen, J. S., Breindahl, M., Krebs, Lone, Christiansen, Michael & Hedley, P. L., 2023, In: Frontiers in Public Health. 10, 12 p., 1039779.

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function

    Escobar-Álvarez, E., Leinisch, F., Araya, G., Monasterio, O., Lorentzen, Lasse Gøbel, Silva, E., Davies, Michael J. & López-Alarcón, C., Nov 2017, In: Free Radical Biology and Medicine. 112, p. 60-68 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The pharmacokinetics, distribution and degradation of human recombinant interleukin 1 beta in normal rats

    Wogensen, L. D., Welinder, B., Hejnaes, K. R., Poulsen, Steen Seier, Nilsson, P. & Nerup, J., Nov 1991, In: Scandinavian Journal of Immunology. 34, 5, p. 597-610 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    The phenotypic spectrum of prrt2-associated paroxysmal neurologic disorders in childhood

    Döring, J. H., Saffari, A., Bast, T., Brockmann, K., Ehrhardt, L., Fazeli, W., Janzarik, W. G., Kluger, G., Muhle, H., Møller, R. S., Platzer, K., Santos, J. L., Bache, I., Bertsche, A., Bonfert, M., Borggräfe, I., Broser, P. J., Datta, A. N., Hammer, T. B., Hartmann, H. & 20 others, Hasse-Wittmer, A., Henneke, M., Kühne, H., Lemke, J. R., Maier, O., Matzker, E., Merkenschlager, A., Opp, J., Patzer, S., Rostasy, K., Stark, B., Strzelczyk, A., von Stülpnagel, C., Weber, Y., Wolff, M., Zirn, B., Hoffmann, G. F., Kölker, S., Syrbe, S. & PRRT2-Study-Group, P., 2020, In: Biomedicines. 8, 11, p. 1-14 14 p., 456.

    Research output: Contribution to journal › Journal article › Research › peer-review

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