Department of Biomedical Sciences

  1. 1999
  2. Published

    Time until initiation of tumor growth is an effective measure of the anti-angiogenic effect of TNP-470 on human glioblastoma in nude mice

    Kragh, M., Spang-Thomsen, M. & Kristjansen, P. E., 1999, In: Oncology Reports. 6, 4, p. 759-62 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Treatment of Type 2 diabetes mellitus based on glucagon-like peptide-1

    Holst, Jens Juul, 1999, In: Exp. Opin. Invest. Drugs. 8, p. 1409-1415

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Ureteral growth in animal models with increased renal excretion of urine

    Thulesen, J., Poulsen, Steen Seier & Nexø, E., 1999, In: Urological Research. 27, 1, p. 41-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Beta cell proliferation and growth factors

    Nielsen, Jens Høiriis, Svensson, C., Møldrup, A., Galsgaard, E. D. & Billestrup, Nils, Jan 1999, In: Journal of Molecular Medicine. 77, 1, p. 62-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Autoantibodies to molecular targets in neutrophils in patients with ulcerative colitis

    Brimnes, J., Nielsen, Ole Haagen, Wiik, A. & Heegaard, N. H. H., 1 Jan 1999, In: Digestive Diseases and Sciences. 44, 2, p. 415-423 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Adrenergic blockade in diabetic and uninephrectomized rats: effects on renal size and on renal and urinary contents of epidermal growth factor

    Thulesen, J., Poulsen, Steen Seier, Jørgensen, P. E. & Nexø, E., Feb 1999, In: Nephron. 81, 2, p. 172-82 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Early death during chemotherapy in patients with small-cell lung cancer: derivation of a prognostic index for toxic death and progression

    Lassen, Ulrik Niels, Osterlind, K., Hirsch, F. R., Bergman, B., Dombernowsky, P. & Hansen, H. H., Feb 1999, In: B J C. 79, 3-4, p. 515-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Caveolin-3 is associated with the T-tubules of mature skeletal muscle fibers

    Ralston, E. & Ploug, Thorkil, 1 Feb 1999, In: Experimental Cell Research. 246, 2, p. 510-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Formation of long-lived radicals on proteins by radical transfer from heme enzymes--a common process?

    Ostdal, H., Andersen, H. J. & Davies, Michael J., 1 Feb 1999, In: Archives of Biochemistry and Biophysics. 362, 1, p. 105-12 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Myoglobin-induced oxidative damage: evidence for radical transfer from oxidized myoglobin to other proteins and antioxidants

    Irwin, J. A., Ostdal, H. & Davies, Michael J., 1 Feb 1999, In: Archives of Biochemistry and Biophysics. 362, 1, p. 94-104 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Glucagon-like peptide-1: a basis for new approaches to the management of diabetes

    Deacon, Carolyn F., Holst, Jens Juul & Carr, R. D., Mar 1999, In: Drugs of Today. 35, 3, p. 159-70 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Role of multistability in the transition to chaotic phase synchronization

    Postnov, D. E., Vadivasova, T. E., Sosnovtseva, Olga, Balanov, A. G., Anishchenko, V. S. & Mosekilde, E., 1 Mar 1999, In: Chaos (Woodbury, N.Y.). 9, 1, p. 227-232 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published

    Synchronization in driven chaotic systems: Diagnostics and bifurcations

    Vadivasova, T., Balanov, A., Sosnovtseva, Olga, Postnov, D. & Mosekilde, E., 15 Mar 1999, In: Physics Letters A. 253, 1-2, p. 66-74

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Experimental observation of coherence resonance in cascaded excitable systems

    Postnov, D. E., Han, S., Yim, T. & Sosnovtseva, Olga, Apr 1999, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). 59, 4, p. R3791-R3794

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Functional testing of a bicistronic retroviral vector for intracellular peptide production

    Duch, M. R., Tolstrup, A., Dalum, I., Jespersen, Thomas, Mouritsen, S. & Pedersen, F. S., 1 Jun 1999, In: BioTechniques. 26, 6, p. 1032-4, 1036

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation

    Hawkins, C. L. & Davies, Michael J., 1 Jun 1999, In: Biochemical Journal. 340 ( Pt 2), p. 539-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Regulation of prolactin receptor (PRLR) gene expression in insulin-producing cells. Prolactin and growth hormone activate one of the rat prlr gene promoters via STAT5a and STAT5b

    Galsgaard, E. D., Møldrup, A. & Nielsen, Jens Høiriis, 25 Jun 1999, In: The Journal of Biological Chemistry. 274, 26, p. 18686-92 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Preservation of veno-arteriolar reflex in the skin following 20 days of head down bed rest in humans

    Gabrielsen, A., Suzuki, Y. & Norsk, P., 1 Jul 1999, In: Journal of Gravitational Physiology. 6, 1, p. P103-4

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Resetting of the carotid arterial baroreflex during dynamic exercise in humans

    Norton, K. H., Boushel, R. C., Andersen, L. S., Saltin, B. & Raven, P. B., 1 Jul 1999, In: Journal of Applied Physiology. 87, 1, p. 332-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Excessive nodular hyperplasia of brunner glands associated with gastric hypersecretion and lipomatous atrophy of the pancreas

    Toøttrup, A., Rokkjær, M., Kruse, A., Poulsen, Steen Seier & Jacobsen, N. O., 13 Jul 1999, In: Scandinavian Journal of Gastroenterology. 34, 5, p. 541-544 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Plasma gelsolin is reduced in trauma patients

    Dahl, Benny, Schiødt, Frank Vinholt, Ott, P., Gvozdenovic, Robert, Yin, H. L. & Lee, W. M., 1 Aug 1999, In: Shock. 12, 2, p. 102-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Interacting coherence resonance oscillators

    Han, S., Yim, T., Postnov, D. & Sosnovtseva, Olga, 30 Aug 1999, In: Physical Review Letters. 83, 9, p. 1771-1774

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Treatment of Type 2 diabetes mellitus based on glucagon-like peptide-1

    Holst, Jens Juul, Sep 1999, In: Expert Opinion on Investigational Drugs. 8, 9, p. 1409-15 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Cerebral desaturation during exercise reversed by O2 supplementation

    Nielsen, H. B., Boushel, R. C., Madsen, P. & Secher, Niels H., 1 Sep 1999, In: American Journal of Physiology (Consolidated). 277, 3 Pt 2, p. H1045-52

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Developmental expression of proprotein convertase 1/3 in the rat

    Lee, Y. C., Damholt, A. B., Billestrup, Nils, Kisbye, T., Galante, P., Michelsen, B., Kofod, H. & Nielsen, Jens Høiriis, 10 Sep 1999, In: Molecular and Cellular Endocrinology. 155, 1-2, p. 27-35 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Proglucagon processing profile in canine L cells expressing endogenous prohormone convertase 1/3 and prohormone convertase 2

    Damholt, A. B., Buchan, A. M., Holst, Jens Juul & Kofod, H., Oct 1999, In: Endocrinology. 140, 10, p. 4800-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Metabolism of oral trefoil factor 2 (TFF2) and the effect of oral and parenteral TFF2 on gastric and duodenal ulcer healing in the rat

    Poulsen, Steen Seier, Thulesen, J., Christensen, L., Nexo, E. & Thim, L., 1 Oct 1999, In: Gut. 45, 4, p. 516-22 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Rectal dialysate and fecal concentrations of neutrophil gelatinase- associated lipocalin, interleukin-8, and tumor necrosis factor-α in ulcerative colitis

    Nielsen, Ole Haagen, Gionchetti, P., Ainsworth, M., Vainer, B., Campieri, M., Borregaard, N. & Kjeldsen, L., 1 Oct 1999, In: American Journal of Gastroenterology. 94, 10, p. 2923-2928 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Hydrolytic properties of a β-mannosidase purified from Aspergillus niger

    Ademark, P., Lundqvist, J., Hägglund, Per Mårten, Tenkanen, M., Torto, N., Tjerneld, F. & Stålbrand, H., 8 Oct 1999, In: Journal of Biotechnology. 75, 2-3, p. 281-289 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Diabetic intestinal growth adaptation and glucagon-like peptide 2 in the rat: effects of dietary fibre

    Thulesen, J., Hartmann, Bolette, Nielsen, C., Holst, Jens Juul & Poulsen, Steen Seier, Nov 1999, In: Gut. 45, 5, p. 672-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine

    Hansen, L., Deacon, Carolyn F., Ørskov, Cathrine & Holst, Jens Juul, Nov 1999, In: Molecular Endocrinology. 140, 11, p. 5356-63 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Immunocytochemical evidence for a paracrine interaction between GIP and GLP-1-producing cells in canine small intestine

    Damholt, A. B., Kofod, H. & Buchan, A. M., Nov 1999, In: Cell and Tissue Research. 298, 2, p. 287-93 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins

    Hansen, J. A., Lindberg, K., Hilton, D. J., Nielsen, Jens Høiriis & Billestrup, Nils, Nov 1999, In: Molecular endocrinology (Baltimore, Md.). 13, 11, p. 1832-43 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Methodological modifications using the microdialysis technique in the peritendinous tissue during exercise.

    Langberg, Henning, Skovgaard, D., Bulow, J. & Kjaer, M., Nov 1999, In: Proceedings of the Nutrition Society. 58, 4, p. 173A-173A

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Phase multistability in quasiperiodically driven systems

    Vadivasova, T., Sosnovtseva, Olga & Balanov, A., Nov 1999, In: Technical Physics Letters. 25, 11, p. 906-908

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The insulinotropic effect of endothelin-1 is mediated by glucagon release from the islet alpha cells

    Brock, B., Gregersen, S., Kristensen, K., Thomsen, J. L., Buschard, K., Kofod, H. & Hermansen, K., Nov 1999, In: Diabetologia. 42, 11, p. 1302-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Expression of heterologous genes from an IRES translational cassette in replication competent murine leukemia virus vectors

    Jespersen, Thomas, Duch, M. R., Carrasco, M. L., Warming, S. & Pedersen, F. S., 1 Nov 1999, In: Gene. 239, 2, p. 227-35 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Histone H1- and other protein- and amino acid-hydroperoxides can give rise to free radicals which oxidize DNA

    Luxford, C., Morin, B., Dean, R. T. & Davies, Michael J., 15 Nov 1999, In: Biochemical Journal. 344 Pt 1, p. 125-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Lipid oxidation in human low-density lipoprotein induced by metmyoglobin/H2O2: involvement of alpha-tocopheroxyl and phosphatidylcholine alkoxyl radicals

    Witting, P. K., Willhite, C. A., Davies, Michael J. & Stocker, R., Dec 1999, In: Chemical Research in Toxicology. 12, 12, p. 1173-81 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Stable markers of oxidant damage to proteins and their application in the study of human disease

    Davies, Michael J., Fu, S., Wang, H. & Dean, R. T., Dec 1999, In: Free Radical Biology & Medicine. 27, 11-12, p. 1151-63 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Loss of lag synchronization in coupled chaotic systems

    Sosnovtseva, Olga, Balanov, A. G., Vadivasova, T. E., Astakhov, V. V. & Mosekilde, E., 1 Dec 1999, In: Physical Review E. Statistical, Nonlinear, and Soft Matter Physics. 60, 6 Pt A, p. 6560-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Reproductive history and stage of breast cancer

    Wohlfahrt, J., Andersen, P., Mouridsen, H., Adami, H. & Melbye, M., 15 Dec 1999, In: American Journal of Epidemiology. 150, 12, p. 1325-1330

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    The organization of the Golgi complex and microtubules in skeletal muscle is fiber type-dependent

    Ralston, E., Lu, Z. & Ploug, Thorkil, 15 Dec 1999, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 19, 24, p. 10694-705 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2000
  47. Published

    1,5-Anhydro fructose increase glucose tolerance by increasing GLP-1 and insulin in mice

    Ahrén, B., Holst, Jens Juul, Marcussen, J. & Yu, S., 2000, In: Eur. J. Pharmacol.. 397, p. 219-225

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    A recessive C-terminal Jervell and Lange-Nielsen mutation of the KCNQ1 channel impairs subunit assembly.

    Schmitt, Nicole, Schwarz, M., Peretz, A., Abitbol, I., Attali, B. & Pongs, O., 2000, In: EMBO Journal. 19, 3, p. 332-40 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3.

    Loechel, F., Fox, J. W., Murphy, G., Albrechtsen, Reidar & Wewer, Ulla M., 2000, In: Biochemical and Biophysical Research Communications. 278, 3, p. 511-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Activity and immunohistochemical localization of porphobilinogen deaminase in rat tissues

    Jørgensen, P. E., Erlandsen, E. J., Poulsen, Steen Seier, Markussen, S. B., Koch, C. & Brock, A., 2000, In: Scandinavian Journal of Clinical & Laboratory Investigation. 60, 7, p. 635-41 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    An investigation into the genotoxic species generated during reduction of chromium(VI) by catechol(amine)s

    Pattison, D. I., Lay, P. A. & Davies, Michael J., 2000, In: Redox Report (Online). 5, 2-3, p. 130-2 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Antidiabetogenic action of cholecystokinin in type 2 diabetes

    Ahrén, B., Holst, Jens Juul & Efendic, S., 2000, In: J. Clin. Endocrinol. Metab.. 85, p. 1043-8

    Research output: Contribution to journalJournal articleResearchpeer-review