Department of Biomedical Sciences

  1. Published

    Rationale and design of the SafeHeart study: Development and testing of a mHealth tool for the prediction of arrhythmic events and implantable cardioverter-defibrillator therapy

    Frodi, D. M., Kolk, M. Z. H., Langford, J., Andersen, Tariq Osman, Knops, R. E., Tan, H. L., Svendsen, Jesper Hastrup, Tjong, F. V. Y. & Diederichsen, S. Z., 2021, In: Cardiovascular Digital Health Journal. 2, 6, p. S11-S20

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression

    Frohlich, C., Nehammer, C., Albrechtsen, Reidar, Kronqvist, P., Kveiborg, Marie, Sehara-Fujisawa, A., Mercurio, A. M. & Wewer, Ulla M., 29 Aug 2011, In: Molecular Cancer Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins

    Frohlich, C., Klitgaard, M., Noer, J. B., Kotzsch, A., Nehammer, C., Kronqvist, P., Berthelsen, J., Blobel, C., Kveiborg, Marie, Albrechtsen, Reidar & Wewer, Ulla M., 15 May 2013, In: Biochemical Journal. 452, 1, p. 97-109 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Effect of 5'-flanking sequence deletions on expression of the human insulin gene in transgenic mice

    Fromont-Racine, M., Bucchini, D., gjc556, gjc556, Desbois, P., Linde, S., Saulnier, C., Ripoche, M. A., Jami, J., Pictet, R. & Nielsen, Jens Høiriis, May 1990, In: Molecular endocrinology (Baltimore, Md.). 4, 5, p. 669-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Skeletal Muscle: A Brief Review of Structure and Function

    Frontera, W. R. & Ochala, Julien, 4 Mar 2015, In: Behavior Genetics. 45, 2, p. 183-195 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    CineECG analysis provides new insights into Familial ST-segment Depression Syndrome

    Frosted, R., Paludan-Müller, Christian, Vad, Oliver Tim Bundgaard, Olesen, Morten Steen Salling, Bundgård, Henning, van Dam, P. & Christensen, Alex Hørby, 2023, In: Europace. 25, 5, 11 p., euad116.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Biomarkers predictive of late cardiogenic shock development in patients with suspected ST-elevation myocardial infarction

    Frydland, M., Moller, J. E., Lindholm, M. G., Hansen, R., Wiberg, S., Helgestad, O. K. L., Thomsen, J. H., Goetze, Jens P. , Engstrøm, Thomas, Frikke-Schmidt, Ruth, Ravn, H. B., Holmvang, Lene, Jensen, L. O., Kjaergaard, J. & Hassager, Christian, 2020, In: European Heart Journal: Acute Cardiovascular Care. 9, 6, p. 557–566

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Disturbances of the sarcoplasmic reticulum and transverse tubular system in 24-h electrostimulated fast-twitch skeletal muscle

    Frías, J. A., Cadefau, J. A., Prats Gavalda, Clara, Morán, M., Megías, A. & Cussó, R., 2005, In: BBA General Subjects. 1668, 1, p. 64-74 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Eksperimentel nuklearmedicin

    Frøkier, J. & Kjær, Andreas, 2011, Klinisk Nuklearmedicin. Christensen, C. B., Loft, A. & Hesse, B. (eds.). 2 ed. Gad, p. 260-265 6 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  10. Published

    Single-copy insertion of transgenes in Caenorhabditis elegans.

    Frøkjær-Jensen, Christian, Davis, M. W., Hopkins, C. E., Newman, B. J., Thummel, J. M., Olesen, Søren-Peter, Grunnet, Morten & Jorgensen, E. M., 2008, In: Nature Genetics. 40, 11, p. 1375-83 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    An Abundant Class of Non-coding DNA Can Prevent Stochastic Gene Silencing in the C. elegans Germline

    Frøkjær-Jensen, Christian, Jain, N., Hansen, L., Davis, M. W., Li, Y., Zhao, D., Rebora, K., Millet, J. R. M., Liu, X., Kim, S. K., Dupuy, D., Jorgensen, E. M. & Fire, A. Z., 14 Jul 2016, In: Cell. 166, 2, p. 343-357 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Plasma Exosome-Enriched Extracellular Vesicles From Lactating Mothers With Type 1 Diabetes Contain Aberrant Levels of miRNAs During the Postpartum Period

    Frørup, C., Mirza, A. H., Yarani, R., Nielsen, L. B., Mathiesen, Elisabeth, Damm, Peter, Svare, J., Engelbrekt, C., Størling, Joachim, Johannesen, Jesper, Mortensen, H. B., Pociot, Flemming & Kaur, S., 2021, In: Frontiers in Immunology. 12, 744509.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Characterization of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC-βH5 beta cells

    Frørup, C., Gerwig, R., Svane, C. A. S., Mendes Lopes de Melo, J., Henriksen, K., Fløyel, T., Pociot, Flemming, Kaur, S. & Størling, Joachim, 2023, In: Frontiers in Endocrinology. 14, 15 p., 1128523.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Effect of liraglutide on ectopic fat in polycystic ovary syndrome: A randomized clinical trial

    Frøssing, S., Nylander, M., Chabanova, E., Frystyk, J., Holst, Jens Juul, Kistorp, Caroline Michaela Nervil, Skouby, Sven O. & Faber, Jens, Jan 2018, In: Diabetes, Obesity and Metabolism. 20, 1, p. 215-218

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque

    Fu, S., Davies, Michael J., Stocker, R. & Dean, R. T., 1 Aug 1998, In: Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Takotsubo cardiomyopathy is an acute cardiac syndrome induced by stress

    Fuchs, A. M., Bang, L. E., Holmvang, Lene, Hasbak, P., Kjær, Andreas & Christensen, T. E., 13 Jun 2016, In: Ugeskrift for Laeger. 178, 24

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1

    Fuchs, S., Herzog, D., Sumara, G., Büchmann-Møller, S., Civenni, G., Wu, X., Chrostek-Grashoff, A., Suter, U., Ricci, R., Relvas, J. B., Brakebusch, Cord Herbert & Sommer, L., 2009, In: Cell Stem Cell. 4, 3, p. 236-47 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Leptin receptor 170 kDa (OB-R170) protein expression is reduced in obese human skeletal muscle: a potential mechanism of leptin resistance

    Fuentes, T., Ara, I., Guadalupe-Grau, A., Larsen, S., Stallknecht, Bente Merete, Olmedillas, H., Santana, A., Helge, Jørn Wulff, Calbet, J. A. L. & Guerra, B., 2010, In: Experimental Physiology. 95, 1, p. 160-71 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    alpha- and beta-casein aggregation induced by riboflavin-sensitized photo-oxidation occurs via di-tyrosine cross-links and is oxygen concentration dependent

    Fuentes-Lemus, E., Silva, E., Leinisch, F., Dorta, E., Lorentzen, Lasse Gøbel, Davies, Michael J. & Lopez-Alarcon, C., 1 Aug 2018, In: Food Chemistry. 256, p. 119-128

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Oxidation of free, peptide and protein tryptophan residues mediated by AAPH-derived free radicals: role of alkoxyl and peroxyl radicals

    Fuentes-Lemus, E., Dorta, E., Escobar, E., Aspee, A., Pino, E., Abasq, M. L., Speisky, H., Silva, E., Lissi, E., Davies, Michael J. & Lopez-Alarcon, C., 2016, In: RSC Advances. 6, 63, p. 57948-57955 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Oxidative damage on proteins is enhanced in crowded environments

    Fuentes Lemus, Eduardo, Gamon, Luke Francis, Lopez-Alarcon, C. & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. S31-S32

    Research output: Contribution to journalConference abstract in journalResearch

  22. Published

    Oxidation of lysozyme induced by peroxyl radicals involves amino acid modifications, loss of activity, and formation of specific crosslinks

    Fuentes Lemus, Eduardo, Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Davies, Michael J. & Lopez-Alarcon, C., 2021, In: Free Radical Biology and Medicine. 167, p. 258-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Photo -oxidation of lysozyme triggered by riboflavin is O 2-dependent, occurs via mixed type 1 and type 2 pathways, and results in inactivation, site-specific damage and intra- and inter -molecular crosslinks

    Fuentes-Lemus, E., Mariotti, M., Reyes, J., Leinisch, F., Hägglund, Per Mårten, Silva, E., Davies, Michael J. & Lopez-Alarcon, C., 2020, In: Free Radical Biology and Medicine. 152, p. 61-73

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Effect of crowding, compartmentalization and nanodomains on protein modification and redox signaling – current state and future challenges

    Fuentes Lemus, Eduardo & Davies, Michael J., 2023, In: Free Radical Biology and Medicine. 196, p. 81-92

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Crowding modulates the glycation of plasma proteins: In vitro analysis of structural modifications to albumin and transferrin and identification of sites of modification

    Fuentes Lemus, Eduardo, Reyes, J. S., López-Alarcón, C. & Davies, Michael J., 2022, In: Free Radical Biology and Medicine. 193, p. 551-566 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Effect of macromolecular crowding on protein oxidation: Consequences on the rate, extent and oxidation pathways

    Fuentes Lemus, Eduardo, Reyes, J. S., Gamon, Luke Francis, López-Alarcón, C. & Davies, Michael J., 2021, In: Redox Biology. 48, 15 p., 102202.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Role of di-tyrosine and di-tryptophan in alpha- and beta-casein cross-linking triggered by riboflavin-induced photo oxidation and peroxyl radicals: [Meeting Abstract]

    Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S60-S60 P-50 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  28. Published

    Oxidative Crosslinking of Peptides and Proteins: Mechanisms of Formation, Detection, Characterization and Quantification

    Fuentes Lemus, Eduardo, Hägglund, Per Mårten, López-Alarcón, C. & Davies, Michael J., 1 Jan 2022, In: Molecules. 27, 1, p. 1-31 15.

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    The enzymes of the oxidative phase of the pentose phosphate pathway as targets of reactive species: consequences for NADPH production

    Fuentes Lemus, Eduardo, Reyes, J. S., Figueroa, J. D., Davies, Michael J. & López-Alarcón, C., 2023, In: Biochemical Society Transactions. 51, 6, p. 2173–2187

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published

    High concentrations of casein proteins exacerbate radical chain reactions and increase the extent of oxidative damage

    Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Food Hydrocolloids. 121, 16 p., 107060.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Tryptophan and Cysteine residues mediate chain reactions and propagation of oxidative damage in concentrated casein solutions

    Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 562 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  32. Published

    Binding of rose bengal to lysozyme modulates photooxidation and cross-linking reactions involving tyrosine and tryptophan

    Fuentes-Lemus, E., Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Lopez-Alarcon, C. & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 143, p. 375-386

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Aggregation of alpha- and beta- caseins induced by peroxyl radicals involves secondary reactions of carbonyl compounds as well as di-tyrosine and di-tryptophan formation

    Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Escobar, E., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 20 Aug 2018, In: Free Radical Biology and Medicine. 124, p. 176-188

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Ectopic expression of the erythrocyte band 3 anion exchange protein, using a new avian retrovirus vector.

    Fuerstenberg, S., Beug, H., Introna, M., Khazaie, K., Muñoz, A., Ness, S., Nordström, K., Sap, J., Stanley, I. & Zenke, M., 1990, In: Journal of Virology. 64, 12, p. 5891-902 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Effects of whey protein and dietary fiber intake on insulin sensitivity, body composition, energy expenditure, blood pressure, and appetite in subjects with abdominal obesity

    Fuglsang-Nielsen, R., Rakvaag, E., Langdahl, B., Knudsen, K. E. B., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K. & Gregersen, S., 2021, In: European Journal of Clinical Nutrition. 75, p. 611–619

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Consumption of nutrients and insulin resistance suppress markers of bone turnover in subjects with abdominal obesity

    Fuglsang-Nielsen, R., Rakvaag, E., Vestergaard, P., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K., Gregersen, S. & Starup-Linde, J., 2020, In: Bone. 133, 9 p., 115230.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes

    Fuhlendorff, J., Rorsman, P., Kofod, H., Brand, C. L., Rolin, B., MacKay, P., Shymko, R. & Carr, R. D., Mar 1998, In: Diabetes. 47, 3, p. 345-51 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    A human apoB100 transgenic mouse expresses human apoB100 in the RPE and develops features of early AMD

    Fujihara, M., Bartels, Emil Daniel, Nielsen, L. B. & Handa, J. T., 2009, In: Experimental Eye Research. 88, 6, p. 1115-23 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Quantitation of progressive muscle fatigue during dynamic leg exercise in humans

    Fulco, C. S., Lewis, S. F., Frykman, P., Boushel, R. C., Smith, S., Harman, E. A., Cymerman, A. & Pandolf, K. B., 1 Dec 1995, In: Journal of Applied Physiology. 79, 6, p. 2154-62 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Muscle fatigue and exhaustion during dynamic leg exercise in normoxia and hypobaric hypoxia

    Fulco, C. S., Lewis, S. F., Frykman, P., Boushel, R. C., Smith, S., Harman, E. A., Cymerman, A. & Pandolf, K. B., 1 Nov 1996, In: Journal of Applied Physiology. 81, 5, p. 1891-900 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. E-pub ahead of print

    TGF-β modulates cell fate in human ES cell-derived foregut endoderm by inhibiting Wnt and BMP signaling

    Funa, N. S., Mjoseng, Heidi K., Raineri, Silvia, Esen, Deniz, Egeskov-Madsen, A. L. R., Quaranta, Roberto, Jørgensen, Mette Christine, Hansen, M. S., van Cuyl Kuylenstierna, J., Jensen, Kim Bak, Miao, Y., Garcia, K. C., Seymour, Philip Allan & Serup, Palle, 16 Jun 2024, (E-pub ahead of print) In: Stem Cell Reports.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Prevention or early cure of type 1 diabetes by intranasal administration of gliadin in NOD mice

    Funda, D., Fundova, P., Hansen, Axel Kornerup & Buschard, K. S., 2014, In: PLOS ONE. 9, 4, 10 p., e94530.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    In-vivo blood velocity and velocity gradient profiles downstream of stented and stentless aortic heart valves

    Funder, J. A., Frost, M. W., Ringgaard, S., Klaaborg, K., Wierup, P., Hjortdal, Vibeke Elisabeth, Nygaard, H. & Hasenkam, J. M., May 2010, In: The Journal of Heart Valve Disease. 19, 3, p. 292-303 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Aortic root distensibility after subcoronary stentless valve implantation

    Funder, J. A., Frost, M. W., Klaaborg, K., Wierup, P., Hjortdal, Vibeke Elisabeth, Nygaard, H. & Hasenkam, J. M., Mar 2012, In: The Journal of Heart Valve Disease. 21, 2, p. 181-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Aortic root distensibility and cross-sectional areas in stented and subcoronary stentless bioprostheses in pigs

    Funder, J. A., Ringgaard, S., Frost, M. W., Wierup, P., Klaaborg, K., Hjortdal, Vibeke Elisabeth, Nygaard, H. & Hasenkam, J. M., Jun 2010, In: Interactive Cardiovascular and Thoracic Surgery. 10, 6, p. 976-80 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Turbulence downstream of subcoronary stentless and stented aortic valves

    Funder, J. A., Frost, M. W., Wierup, P., Klaaborg, K., Hjortdal, Vibeke Elisabeth, Nygaard, H. & Hasenkam, J. M., 11 Aug 2011, In: Journal of Biomechanics. 44, 12, p. 2273-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.

    Furuta, M., Yano, H., Zhou, A., Rouille, Y., Holst, Jens Juul, Carroll, R., Ravazzolla, M., Orci, L. & Steiner, D. F., 1997, In: Proc. Natl. Acad. Sci.. 94, p. 6646-6651

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    90K (MAC-2 BP) gene expression in breast cancer and evidence for the production of 90K by peripheral-blood mononuclear cells.

    Fusco, O., Querzoli, P., Nenci, I., Natoli, C., Brakebusch, Cord Herbert, Ullrich, A. & Iacobelli, S., 1998, In: International Journal of Cancer. 79, 1, p. 23-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Glucagon-Like Peptide-1 (GLP-1) Response to Oral Glucose is Reduced in Pre-diabetes, Screen-detected Type 2 Diabetes and Obesity, and Influenced by Sex: The ADDITION-PRO Study

    Færch, K., Torekov, Signe Sørensen, Vistisen, D., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Sandbæk, A., Holst, Jens Juul & Jørgensen, M. E., Jul 2015, In: Diabetes. 64, p. 2513-25 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Effects of angiotensin II receptor blockade on cerebral, cardiovascular, counter-regulatory, and symptomatic responses during hypoglycaemia in patients with type 1 diabetes

    Færch, L. H., Thorsteinsson, B., Tarnow, L., Holst, Jens Juul, Kjær, T. W., Kanters, Jørgen K., Larroude, C., Dela, Flemming & Pedersen-Bjergaard, Ulrik, Dec 2015, In: Journal of the Renin-Angiotensin-Aldosterone System. 16, 4, p. 1036-1045 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Blood lactate is an important energy source for the human brain

    van Hall, Gerrit, Stromstad, M., Rasmussen, P., Jans, O., Zaar, M., Gam, C. M. B., Quistorff, B., Secher, Niels H. & Nielsen, H. B., 2009, In: Journal of Cerebral Blood Flow and Metabolism. 29, 6, p. 1121-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Growth of the endocrine pancreas: Identification of candidate genes and regulatory networks involved in beta cell expansion in pregnancy and around birth

    Gaarn, L. W., 2009, Københavns Universitet, Sundhedsvidenskablige fakultet: Museum Tusculanum.

    Research output: Book/ReportPh.D. thesisResearch

  53. Published

    The natural GIP receptor mutation E345Q displays enhanced signalling and internaliation mimicking GIP receptor desensitisation: [Meeting Abstract}

    Gabe, M. B. N., 2019, In: Diabetologia. 62, Supl. 1/SI, p. S231-S231 471.

    Research output: Contribution to journalConference abstract in journalResearch

  54. Published

    GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment

    Gabe, M. B. N., Skov-Jeppesen, Kirsa, Gasbjerg, Lærke Smidt, Schiellerup, S. P., Martinussen, C., Gadgaard, S., Boer, G. A., Oeke, J., Pedersen, Lola Julie Torz, Veedfald, Simon, Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: Pharmacological Research. 176, 106058.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system

    Gabe, M. B. N., van der Velden, W. J. C., Gadgaard, S., Smit, F. X., Hartmann, Bolette, Bräuner, Hans & Rosenkilde, Mette, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, p. 122-132

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice

    Gabe, M. B. N., Christensen, Liv von Voss, Dal, Jenna Elizabeth Hunt, Gadgaard, S., Gasbjerg, Lærke Smidt, Holst, Jens Juul, Kissow, Hannelouise, Hartmann, Bolette & Rosenkilde, Mette, Jan 2023, In: British Journal of Pharmacology. 180, 13, p. 1674-1689

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Human GIP(3-30)NH inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors

    Gabe, M. B. N., Sparre-Ulrich, A. H., Pedersen, M. F., Gasbjerg, Lærke Smidt, Inoue, A., Bräuner, Hans, Hartmann, Bolette & Rosenkilde, M. M., 31 Jan 2018, In: Biochemical Pharmacology. 150, p. 97-107 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Molecular interactions of full-length and truncated GIP peptides with the GIP receptor - A comprehensive review

    Gabe, M. B. N., van der Velden, W. J. C., Smit, F. X., Gasbjerg, Lærke Smidt & Rosenkilde, Mette, 2020, In: Peptides. 125, 8 p., 170224.

    Research output: Contribution to journalReviewResearchpeer-review

  59. Published

    N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction

    Gabe, M. B. N., Gasbjerg, Lærke Smidt, Gadgaard, S., Lindquist, Peter, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4473-4485

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    A comparison of tools for copy-number variation detection in germline whole exome and whole genome sequencing data

    Gabrielaite, M., Torp, M. H., Rasmussen, Malthe Sebro, Andreu-Sánchez, S., Vieira, Filipe Garrett, Pedersen, C. B., Kinalis, S., Madsen, M. B., Kodama, M., Demircan, G. S., Simonyan, A., Yde, C. W., Olsen, L. R., Marvig, R. L., Østrup, O., Rossing, Caroline Maria, Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2021, In: Cancers. 13, 24, 6283.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Preservation of veno-arteriolar reflex in the skin following 20 days of head down bed rest in humans

    Gabrielsen, A., Suzuki, Y. & Norsk, P., 1 Jul 1999, In: Journal of Gravitational Physiology. 6, 1, p. P103-4

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Systemic vascular resistance during brief withdrawal of angiotensin converting enzyme inhibition in heart failure

    Gabrielsen, A., Bie, P., Christensen, N. J., Frandsen, E., Galatius, S., Pump, B., Sørensen, Vibeke Bønnelykke, Kastrup, J. & Norsk, P., 1 Jan 2002, In: Scandinavian Journal of Clinical & Laboratory Investigation. 62, 4, p. 245-54 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Neuroendocrine and renal effects of intravascular volume expansion in compensated heart failure.

    Gabrielsen, A., Bie, P., von Holstein-Rathlou, Niels-Henrik, Christensen, N. J., Warberg, J., Dige-Petersen, H., Frandsen, E., Galatius, S., Pump, B., Sørensen, V. B., Kastrup, J. & Norsk, P., 2001, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 281, 2, p. R459-67

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Atrial distension, haemodilution, and acute control of renin release during water immersion in humans

    Gabrielsen, A., Pump, B., Bie, P., Christensen, N. J., Warberg, J. & Norsk, P., 1 Feb 2002, In: Acta Physiologica Scandinavica. Supplementum. 174, 2, p. 91-99 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Effect of spaceflight on the subcutaneous venoarteriolar reflex in the human lower leg.

    Gabrielsen, A. & Norsk, P., 2007, In: Journal of Applied Physiology. 103, 3, p. 959-62 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Non-invasive measurement of cardiac output in heart failure patients using a new foreign gas rebreathing technique.

    Gabrielsen, A., Videbaek, R., Schou, M., Damgaard, M., Kastrup, J. & Norsk, P., 2002, In: Clinical Science. 102, 2, p. 247-52 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Asthma affects time to pregnancy and fertility: a register-based twin study

    Gade, E. J., Thomsen, Simon Francis, Lindenberg, S., Kyvik, K. O., Lieberoth, S. & Backer, Vibeke, Apr 2014, In: European Respiratory Journal. 43, 4, p. 1077-1085 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Fertility outcomes in asthma: a clinical study of 245 women with unexplained infertility

    Gade, E. J., Thomsen, Simon Francis, Lindenberg, S. & Backer, Vibeke, Apr 2016, In: The European Respiratory Journal. 47, 4, p. 1144-1151 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Novel agonist- and antagonist-based radioligands for the GLP-2 receptor - useful tools for studies of basic GLP-2R pharmacology

    Gadgaard, S., van der Velden, W. J. C., Schiellerup, S. P., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Boer, G. A., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: British Journal of Pharmacology. 179, 9, p. 1998-2015

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Long-acting agonists of human and rodent GLP-2 receptors for studies of the physiology and pharmacological potential of the GLP-2 system

    Gadgaard, S., Windeløv, Johanne Agerlin, Schiellerup, S. P., Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, Mette, 2023, In: Biomedicine and Pharmacotherapy. 160, 13 p., 114383.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Multifactorial intervention and mortallity in type 2 diabetes- Reply

    Gaede, P., Parving, H. & Pedersen, Oluf Borbye, 2008, In: New England Journal of Medicine. p. 358: 2292-2293

    Research output: Contribution to journalComment/debateResearch

  72. Published

    Cost-effectiveness of intensified versus conventional multifactorial intervention in type 2 diabetes: results and projections from the Steno-2 study

    Gaede, P., Valentine, W. J., Palmer, A. J., Tucker, D. M. D., Lammert, M., Parving, H. & Pedersen, Oluf Borbye, 2008, In: Diabetes Care. 31, 8, p. 1510-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Effect of a multifactorial intervention on mortality in type 2 diabetes

    Gaede, P., Lund-Andersen, H., Parving, H. & Pedersen, Oluf Borbye, 2008, In: New England Journal of Medicine. 358, 6, p. 580-91 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Christian Bohr - far til ligning, effekt og Niels

    Galbo, Henrik, 2007, In: Ugeskrift for læger. 169, 35, p. 2872

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Responses to acute exercise in type 2 diabetes, with an emphasis on metabolism and interaction with oral hypoglycemic agents and food intake

    Galbo, Henrik, Tobin, L. & Loon, L. J. C. V., 2007, In: Applied Physiology, Nutrition and Metabolism. 32, 3, p. 567-575 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Xanthine oxidase activity and free radical generation in patients with sepsis syndrome

    Galley, H. F., Davies, Michael J. & Webster, N. R., 1996, In: Critical Care Medicine. 24, 10, p. 1649-53 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Prdm5 suppresses Apc(Min)-driven intestinal adenomas and regulates monoacylglycerol lipase expression

    Galli, G. G., Multhaupt, H. A., Carrara, M., Honnens de Lichtenberg, K., Christensen, I. B. J., Linnemann, D., Santoni Rugiu, Eric, Calogero, R. A. & Lund, Anders H., 22 Jul 2013, In: Oncogene.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Prdm5 Regulates Collagen Gene Transcription by Association with RNA Polymerase II in Developing Bone

    Galli, G. G., Honnens de Lichtenberg, K., Carrara, M., Hans, W., Wuelling, M., Mentz, B., Multhaupt, H. A., Tonnesen, C. K. F., Jensen, K. T., Rappsilber, J., Vortkamp, A., Coulton, L., Fuchs, H., Gailus-Durner, V., Hrabe de Angelis, M., Calogero, R. A., Couchman, John Robert & Lund, Anders H., 2012, In: P L o S Genetics (Online). 8, 5, p. e1002711

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Regulation of prolactin receptor (PRLR) gene expression in insulin-producing cells. Prolactin and growth hormone activate one of the rat prlr gene promoters via STAT5a and STAT5b

    Galsgaard, E. D., Møldrup, A. & Nielsen, Jens Høiriis, 25 Jun 1999, In: The Journal of Biological Chemistry. 274, 26, p. 18686-92 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Expression of dominant-negative STAT5 inhibits growth hormone- and prolactin-induced proliferation of insulin-producing cells

    Galsgaard, E. D., Friedrichsen, B. N., Møldrup, A. & Nielsen, Jens Høiriis, 2001, In: Diabetes. 50 Suppl 1, Vol.50, Suppl.1, p. 40-41

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Identification of a growth hormone-responsive STAT5-binding element in the rat insulin 1 gene

    Galsgaard, E. D., Gouilleux, F., Groner, B., Serup, Palle, Billestrup, Nils & Nielsen, Jens Høiriis, Jun 1996, In: Molecular endocrinology (Baltimore, Md.). 10, 6, p. 652-60 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Glucagon promotes hepatic autophagy by AMPK-mediated mTORC1 inhibition

    Galsgaard, Katrine Douglas, Lee, J., Hubbard, B. T., Zhang, X. -., Cline, G. W., Nasiri, A. R., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Pertersen, K. F. & Shulman, G. I., 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S232

    Research output: Contribution to journalConference abstract in journalResearch

  83. Published

    Glucagon Receptor Signaling and Lipid Metabolism

    Galsgaard, Katrine Douglas, Pedersen, Jens, Knop, Filip Krag, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2019, In: Frontiers in Physiology. 10, 11 p., 413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Glucose and Amino Acid Metabolism in Mice Depend Mutually on Glucagon and Insulin Receptor Signaling

    Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Pedersen, Jens, Kjeldsen, Sasha Alexandra Sampson, Rosenkilde, Mette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 4, p. E660-E673

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published
  86. Published

    Alanine, arginine, cysteine, and proline, but not glutamine, are substrates for, and acute mediators of, the liver-α-cell axis in female mice

    Galsgaard, Katrine Douglas, Jepsen, Sara Lind, Kjeldsen, Sasha Alexandra Sampson, Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 6, p. E920-E929 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Glucagon receptor signaling is not required for N-carbamoyl glutamate- And L-citrulline-induced ureagenesis in mice

    Galsgaard, Katrine Douglas, Pedersen, Jens, Kjeldsen, Sasha Alexandra Sampson, Winther-Sørensen, Marie, Stojanovska, E., Vilstrup, H., Ørskov, Cathrine, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 5, p. G912-G927

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis

    Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørskov, Cathrine, Kissow, Hannelouise, Poulsen, Steen Seier, Vilstrup, H., Prehn, C., Adamski, J., Jepsen, Sara Lind, Hartmann, Bolette, Dal, Jenna Elizabeth Hunt, Charron, M. J., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 1, p. E93-E103

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    The Vicious Circle of Hepatic Glucagon Resistance in Non-Alcoholic Fatty Liver Disease

    Galsgaard, Katrine Douglas, 2020, In: Journal of Clinical Medicine. 9, 12, 11 p., 4049.

    Research output: Contribution to journalReviewResearchpeer-review

  90. Published

    Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness

    Galvan-Alvarez, V., Gallego-Selles, A., Martinez-Canton, M., García-Gonzalez, E., Gelabert-Rebato, M., Ponce-Gonzalez, J. G., Larsen, Steen, Morales-Alamo, D., Losa-Reyna, J., Perez-Suarez, I., Dorado, C., Perez-Valera, M., Holmberg, H. C., Boushel, R., de Pablos Velasco, P., Helge, Jørn Wulff, Martin-Rincon, M. & Calbet, J. A. L., 2023, In: Free Radical Biology and Medicine. 209, p. 282-291 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Maintained cerebral metabolic ratio during exercise in patients with beta-adrenergic blockade

    Gam, C. M. B., Rasmussen, P., Secher, N. H., Seifert, T., Larsen, F. S., Nielsen, H. B. & Gam, C. M. B., Nov 2009, In: Clinical Physiology and Functional Imaging. 29, 6, p. 420-426 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    A model for the distribution of daily number of births in obstetric clinics based on a descriptive retrospective study

    Gam, C. M. B., Tanniou, J., Keiding, N. & Løkkegaard, E. L., 2013, In: B M J Open. 3, 8, p. e002920 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    In cirrhotic patients reduced muscle strength is unrelated to muscle capacity for ATP turnover suggesting a central limitation

    Gam, C. M. B., Nielsen, H. B., Secher, Niels H., Larsen, F. S., Ott, P. & Quistorff, B., May 2011, In: Clinical Physiology and Functional Imaging. 31, 3, p. 169-74 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Unchanged mitochondrial phenotype, but accumulation of lipids in the myometrium in obese pregnant women

    Gam, C. M. B. F., Larsen, L. H., Mortensen, Ole Hartvig, pjx571, pjx571, Poulsen, Steen Seier, Qvortrup, Klaus, Mathiesen, Elisabeth, Damm, Peter & Quistorff, B., Dec 2017, In: Journal of Physiology. 595, 23, p. 7109-7122 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Diabetes, myometrium, and mitochondria in pregnant women at term

    Gam, C. M. B. F., Mortensen, Ole Hartvig, Larsen, L. H., Poulsen, Steen Seier, Qvortrup, Klaus, Mathiesen, Elisabeth, Damm, Peter & Quistorff, B., 2018, In: Acta Diabetologica. 55, 10, p. 999–1010

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Erratum to: Effect of high-fat diet on rat myometrium during pregnancy—isolated myometrial mitochondria are not affected (Pflugers Arch - Eur J Physiol, (2015), 467, (1539–1549), 10.1007/s00424-014-1599-7)

    Gam, C. M. B. F., Mortensen, Ole Hartvig, Qvortrup, Klaus, Damm, Peter & Quistorff, B., 1 Sep 2017, In: Pflugers Archiv European Journal of Physiology. 469, 9, p. 1229 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  97. Published

    Effect of high-fat diet on rat myometrium during pregnancy-isolated myometrial mitochondria are not affected

    Gam, C. M. B. F., Mortensen, Ole Hartvig, Qvortrup, Klaus, Damm, Peter & Quistorff, B., 21 Aug 2014, In: Pflügers Archiv - European Journal of Physiology. 467, 7, p. 1539-1549 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase

    Gamon, Luke Francis, Dieterich, S., Ignasiak, M. T., Schrameyer, V. & Davies, Michael J., 2020, In: Redox Biology. 28, 12 p., 101331.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Absolute quantitative analysis of intact and oxidised amino acids by LCMS without prior derivatization: [Meeting Abstract]

    Gamon, Luke Francis & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S25-S25 70.

    Research output: Contribution to journalConference abstract in journalResearch

  100. Published

    Iodide modulates myeloperoxidase-derived oxidative damage to extracellular matrix proteins: [Meeting Abstract]

    Gamon, Luke Francis, Ignasiak, M. T., Dieterich, S. D., Sauerland, Max Benjamin, Goll, S. T. & Davies, Michael J., 1 Aug 2019, In: Free Radical Biology and Medicine. 139, S1, p. S8-S8 2.

    Research output: Contribution to journalConference abstract in journalResearch