Skeletmuskulaturens metaboliske kapacitet og sundhed

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Skeletmuskulaturens metaboliske kapacitet og sundhed. / Saltin, B; Helge, Jørn Wulff.

In: Ugeskrift for Laeger, Vol. 162, No. 15, 10.04.2000, p. 2159-64.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Saltin, B & Helge, JW 2000, 'Skeletmuskulaturens metaboliske kapacitet og sundhed', Ugeskrift for Laeger, vol. 162, no. 15, pp. 2159-64.

APA

Saltin, B., & Helge, J. W. (2000). Skeletmuskulaturens metaboliske kapacitet og sundhed. Ugeskrift for Laeger, 162(15), 2159-64.

Vancouver

Saltin B, Helge JW. Skeletmuskulaturens metaboliske kapacitet og sundhed. Ugeskrift for Laeger. 2000 Apr 10;162(15):2159-64.

Author

Saltin, B ; Helge, Jørn Wulff. / Skeletmuskulaturens metaboliske kapacitet og sundhed. In: Ugeskrift for Laeger. 2000 ; Vol. 162, No. 15. pp. 2159-64.

Bibtex

@article{3ff67f943985426183e4857f492d6fe6,
title = "Skeletmuskulaturens metaboliske kapacitet og sundhed",
abstract = "The metabolic capacity of skeletal muscle plays a significant role for insulin sensitivity and the blood lipid profile. The metabolic capacity of the muscle is a function of the individual's physical activity level. This is also true for the content of type IIx muscle fibres, which is reduced and the number of capillaries, which is elevated with muscle usage. Several of these skeletal muscle features are risk factors for or linked with life style-induced diseases such as type II diabetes, hypertension, hyperlipidaemia and obesity. This central role of the skeletal muscle and its functional metabolic capacity for life style diseases highlights the importance of people maintaining daily physical activity. This article focuses on the link between the metabolic capacity of skeletal muscle and the metabolic syndrome and briefly discusses possible metabolic explanations for this relationship. An important aspect is that when skeletal muscle has a high capacity for lipid oxidation more saturated fatty acids are oxidized and more unsaturated fatty acids are built into the phospholipid fraction of the plasma membrane, giving it more fluidity and improved insulin sensitivity. Moreover, the article points at the role of these fatty acids in activating genes via the PPAR-receptor system essential for enzyme and transport proteins in the lipid metabolism.",
keywords = "Exercise, Health Status, Humans, Hypertension, Insulin Resistance, Lipid Metabolism, Muscle Contraction, Muscle Fibers, Skeletal, Muscle, Skeletal, Risk Factors",
author = "B Saltin and Helge, {J{\o}rn Wulff}",
year = "2000",
month = apr,
day = "10",
language = "Dansk",
volume = "162",
pages = "2159--64",
journal = "Ugeskrift for Laeger",
issn = "0041-5782",
publisher = "Almindelige Danske Laegeforening",
number = "15",

}

RIS

TY - JOUR

T1 - Skeletmuskulaturens metaboliske kapacitet og sundhed

AU - Saltin, B

AU - Helge, Jørn Wulff

PY - 2000/4/10

Y1 - 2000/4/10

N2 - The metabolic capacity of skeletal muscle plays a significant role for insulin sensitivity and the blood lipid profile. The metabolic capacity of the muscle is a function of the individual's physical activity level. This is also true for the content of type IIx muscle fibres, which is reduced and the number of capillaries, which is elevated with muscle usage. Several of these skeletal muscle features are risk factors for or linked with life style-induced diseases such as type II diabetes, hypertension, hyperlipidaemia and obesity. This central role of the skeletal muscle and its functional metabolic capacity for life style diseases highlights the importance of people maintaining daily physical activity. This article focuses on the link between the metabolic capacity of skeletal muscle and the metabolic syndrome and briefly discusses possible metabolic explanations for this relationship. An important aspect is that when skeletal muscle has a high capacity for lipid oxidation more saturated fatty acids are oxidized and more unsaturated fatty acids are built into the phospholipid fraction of the plasma membrane, giving it more fluidity and improved insulin sensitivity. Moreover, the article points at the role of these fatty acids in activating genes via the PPAR-receptor system essential for enzyme and transport proteins in the lipid metabolism.

AB - The metabolic capacity of skeletal muscle plays a significant role for insulin sensitivity and the blood lipid profile. The metabolic capacity of the muscle is a function of the individual's physical activity level. This is also true for the content of type IIx muscle fibres, which is reduced and the number of capillaries, which is elevated with muscle usage. Several of these skeletal muscle features are risk factors for or linked with life style-induced diseases such as type II diabetes, hypertension, hyperlipidaemia and obesity. This central role of the skeletal muscle and its functional metabolic capacity for life style diseases highlights the importance of people maintaining daily physical activity. This article focuses on the link between the metabolic capacity of skeletal muscle and the metabolic syndrome and briefly discusses possible metabolic explanations for this relationship. An important aspect is that when skeletal muscle has a high capacity for lipid oxidation more saturated fatty acids are oxidized and more unsaturated fatty acids are built into the phospholipid fraction of the plasma membrane, giving it more fluidity and improved insulin sensitivity. Moreover, the article points at the role of these fatty acids in activating genes via the PPAR-receptor system essential for enzyme and transport proteins in the lipid metabolism.

KW - Exercise

KW - Health Status

KW - Humans

KW - Hypertension

KW - Insulin Resistance

KW - Lipid Metabolism

KW - Muscle Contraction

KW - Muscle Fibers, Skeletal

KW - Muscle, Skeletal

KW - Risk Factors

M3 - Tidsskriftartikel

C2 - 10776058

VL - 162

SP - 2159

EP - 2164

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

IS - 15

ER -

ID: 33864855