Role of peripheral vascular resistance for the association between major depression and cardiovascular disease

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Role of peripheral vascular resistance for the association between major depression and cardiovascular disease. / Bouzinova, Elena V.; Wiborg, Ove; Aalkjaer, Christian; Matchkov, Vladimir V.

In: Journal of Cardiovascular Pharmacology, Vol. 65, No. 4, 04.2015, p. 299-307.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Bouzinova, EV, Wiborg, O, Aalkjaer, C & Matchkov, VV 2015, 'Role of peripheral vascular resistance for the association between major depression and cardiovascular disease', Journal of Cardiovascular Pharmacology, vol. 65, no. 4, pp. 299-307. https://doi.org/10.1097/FJC.0000000000000187

APA

Bouzinova, E. V., Wiborg, O., Aalkjaer, C., & Matchkov, V. V. (2015). Role of peripheral vascular resistance for the association between major depression and cardiovascular disease. Journal of Cardiovascular Pharmacology, 65(4), 299-307. https://doi.org/10.1097/FJC.0000000000000187

Vancouver

Bouzinova EV, Wiborg O, Aalkjaer C, Matchkov VV. Role of peripheral vascular resistance for the association between major depression and cardiovascular disease. Journal of Cardiovascular Pharmacology. 2015 Apr;65(4):299-307. https://doi.org/10.1097/FJC.0000000000000187

Author

Bouzinova, Elena V. ; Wiborg, Ove ; Aalkjaer, Christian ; Matchkov, Vladimir V. / Role of peripheral vascular resistance for the association between major depression and cardiovascular disease. In: Journal of Cardiovascular Pharmacology. 2015 ; Vol. 65, No. 4. pp. 299-307.

Bibtex

@article{3d3fb0848ba3441ba90b5f0d284e4d1e,
title = "Role of peripheral vascular resistance for the association between major depression and cardiovascular disease",
abstract = "Major depression and cardiovascular diseases are 2 of the most prevalent health problems in Western society, and an association between them is generally accepted. Although the specific mechanism behind this comorbidity remains to be elucidated, it is clear that it has a complex multifactorial character including a number of neuronal, humoral, immune, and circulatory pathways. Depression-associated cardiovascular abnormalities associate with cardiac dysfunctions and with changes in peripheral resistance. Although cardiac dysfunction in association with depression has been studied in detail, little attention was given to structural and functional changes in resistance arteries responsible for blood pressure control and tissue perfusion. This review discusses recent achievements in studies of depression-associated abnormalities in resistance arteries in humans and animal experimental models. The changes in arterial structure, contractile and relaxing functions associated with depression symptoms are discussed, and the role of these abnormalities for the pathology of major depression and cardiovascular diseases are suggested.",
keywords = "Animals, Blood Vessels, Cardiovascular Diseases, Comorbidity, Depressive Disorder, Major, Humans, Vascular Resistance",
author = "Bouzinova, {Elena V.} and Ove Wiborg and Christian Aalkjaer and Matchkov, {Vladimir V.}",
year = "2015",
month = apr,
doi = "10.1097/FJC.0000000000000187",
language = "English",
volume = "65",
pages = "299--307",
journal = "Journal of Cardiovascular Pharmacology",
issn = "0160-2446",
publisher = "Lippincott Williams & Wilkins",
number = "4",

}

RIS

TY - JOUR

T1 - Role of peripheral vascular resistance for the association between major depression and cardiovascular disease

AU - Bouzinova, Elena V.

AU - Wiborg, Ove

AU - Aalkjaer, Christian

AU - Matchkov, Vladimir V.

PY - 2015/4

Y1 - 2015/4

N2 - Major depression and cardiovascular diseases are 2 of the most prevalent health problems in Western society, and an association between them is generally accepted. Although the specific mechanism behind this comorbidity remains to be elucidated, it is clear that it has a complex multifactorial character including a number of neuronal, humoral, immune, and circulatory pathways. Depression-associated cardiovascular abnormalities associate with cardiac dysfunctions and with changes in peripheral resistance. Although cardiac dysfunction in association with depression has been studied in detail, little attention was given to structural and functional changes in resistance arteries responsible for blood pressure control and tissue perfusion. This review discusses recent achievements in studies of depression-associated abnormalities in resistance arteries in humans and animal experimental models. The changes in arterial structure, contractile and relaxing functions associated with depression symptoms are discussed, and the role of these abnormalities for the pathology of major depression and cardiovascular diseases are suggested.

AB - Major depression and cardiovascular diseases are 2 of the most prevalent health problems in Western society, and an association between them is generally accepted. Although the specific mechanism behind this comorbidity remains to be elucidated, it is clear that it has a complex multifactorial character including a number of neuronal, humoral, immune, and circulatory pathways. Depression-associated cardiovascular abnormalities associate with cardiac dysfunctions and with changes in peripheral resistance. Although cardiac dysfunction in association with depression has been studied in detail, little attention was given to structural and functional changes in resistance arteries responsible for blood pressure control and tissue perfusion. This review discusses recent achievements in studies of depression-associated abnormalities in resistance arteries in humans and animal experimental models. The changes in arterial structure, contractile and relaxing functions associated with depression symptoms are discussed, and the role of these abnormalities for the pathology of major depression and cardiovascular diseases are suggested.

KW - Animals

KW - Blood Vessels

KW - Cardiovascular Diseases

KW - Comorbidity

KW - Depressive Disorder, Major

KW - Humans

KW - Vascular Resistance

U2 - 10.1097/FJC.0000000000000187

DO - 10.1097/FJC.0000000000000187

M3 - Journal article

C2 - 25469807

VL - 65

SP - 299

EP - 307

JO - Journal of Cardiovascular Pharmacology

JF - Journal of Cardiovascular Pharmacology

SN - 0160-2446

IS - 4

ER -

ID: 154482583