Reduction in cardiovascular risk factors and insulin dose, but no beta-cell regeneration 1 year after Roux-en-Y gastric bypass in an obese patient with type 1 diabetes: a case report
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Reduction in cardiovascular risk factors and insulin dose, but no beta-cell regeneration 1 year after Roux-en-Y gastric bypass in an obese patient with type 1 diabetes : a case report. / Dirksen, Carsten; Jacobsen, Siv H; Bojsen-Møller, Kirstine N; Jørgensen, Nils B; Naver, Lars S; Hvolris, Lisbeth E; Worm, Dorte; Madsbad, Sten; Holst, Jens Juul; Hansen, Dorte L.
In: Obesity Research & Clinical Practice, Vol. 7, No. 4, 07.12.2013, p. e269-74.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Reduction in cardiovascular risk factors and insulin dose, but no beta-cell regeneration 1 year after Roux-en-Y gastric bypass in an obese patient with type 1 diabetes
T2 - a case report
AU - Dirksen, Carsten
AU - Jacobsen, Siv H
AU - Bojsen-Møller, Kirstine N
AU - Jørgensen, Nils B
AU - Naver, Lars S
AU - Hvolris, Lisbeth E
AU - Worm, Dorte
AU - Madsbad, Sten
AU - Holst, Jens Juul
AU - Hansen, Dorte L
N1 - © 2013 Asian Oceanian Association for the Study of Obesity . Published by Elsevier Ltd. All rights reserved.
PY - 2013/12/7
Y1 - 2013/12/7
N2 - Experience with Roux-en-Y gastric bypass in patients with type 1 diabetes is very limited, despite an increasing prevalence of obesity also in this population. We describe changes in anthropometric measures, insulin dose, HbA1c, blood pressure, lipid status, and metabolic response to a liquid mixed meal throughout the first year after RYGB in an obese patient with type 1 diabetes. No change in HbA1c was observed, but a 48% reduction in weight-adjusted insulin dose and improvements in cardiovascular risk factors was seen 1 year after surgery. Exaggerated secretions of anorexigenic gut hormones were seen during the meals.
AB - Experience with Roux-en-Y gastric bypass in patients with type 1 diabetes is very limited, despite an increasing prevalence of obesity also in this population. We describe changes in anthropometric measures, insulin dose, HbA1c, blood pressure, lipid status, and metabolic response to a liquid mixed meal throughout the first year after RYGB in an obese patient with type 1 diabetes. No change in HbA1c was observed, but a 48% reduction in weight-adjusted insulin dose and improvements in cardiovascular risk factors was seen 1 year after surgery. Exaggerated secretions of anorexigenic gut hormones were seen during the meals.
U2 - 10.1016/j.orcp.2012.01.002
DO - 10.1016/j.orcp.2012.01.002
M3 - Journal article
C2 - 24306154
VL - 7
SP - e269-74
JO - Obesity Research and Clinical Practice
JF - Obesity Research and Clinical Practice
SN - 1871-403X
IS - 4
ER -
ID: 117852898