NNMT: A Bad Actor in Fat Makes Good in Liver
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NNMT : A Bad Actor in Fat Makes Good in Liver. / Trammell, Samuel A.J.; Brenner, Charles.
In: Cell Metabolism, Vol. 22, No. 2, 04.08.2015, p. 200-201.Research output: Contribution to journal › Editorial › Research › peer-review
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TY - JOUR
T1 - NNMT
T2 - A Bad Actor in Fat Makes Good in Liver
AU - Trammell, Samuel A.J.
AU - Brenner, Charles
PY - 2015/8/4
Y1 - 2015/8/4
N2 - High adipose expression of NNMT, an enzyme that converts nicotinamide to 1-methyl-nicotinamide, correlates with adiposity. Though murine NNMT knockdown in fat and liver prevents weight gain on high-fat diet, Hong et al. (2015) now show that high hepatic expression of NNMT improves lipid parameters via SIRT1 stabilization.
AB - High adipose expression of NNMT, an enzyme that converts nicotinamide to 1-methyl-nicotinamide, correlates with adiposity. Though murine NNMT knockdown in fat and liver prevents weight gain on high-fat diet, Hong et al. (2015) now show that high hepatic expression of NNMT improves lipid parameters via SIRT1 stabilization.
UR - http://www.scopus.com/inward/record.url?scp=84938593243&partnerID=8YFLogxK
U2 - 10.1016/j.cmet.2015.07.017
DO - 10.1016/j.cmet.2015.07.017
M3 - Editorial
C2 - 26244929
AN - SCOPUS:84938593243
VL - 22
SP - 200
EP - 201
JO - Cell Metabolism
JF - Cell Metabolism
SN - 1550-4131
IS - 2
ER -
ID: 220855659