Immunoassays of human trefoil factors 1 and 2: measured on serum from patients with inflammatory bowel disease
Research output: Contribution to journal › Journal article › Research › peer-review
The trefoil factors (TFF1-3) are cysteine-rich peptides expressed in the gastrointestinal tract where they play a critical role in mucosal protection and repair. The expression is up-regulated at sites of ulceration in various chronic inflammatory diseases. Recently, we presented an ELISA method for measurement of TFF3. The aims of the present study were to develop and evaluate ELISAs for the other two known human trefoil peptides, TFF1 and TFF2, and to carry out a cross-sectional study on serum TFF levels in patients with inflammatory bowel disease (IBD).
| Original language | English |
|---|---|
| Journal | Scandinavian Journal of Clinical & Laboratory Investigation |
| Volume | 64 |
| Issue number | 2 |
| Pages (from-to) | 146-56 |
| Number of pages | 11 |
| ISSN | 0036-5513 |
| Publication status | Published - Apr 2004 |
- Adolescent, Adult, Aged, Aging, Enzyme-Linked Immunosorbent Assay, Female, Health, Humans, Immunoassay, Inflammatory Bowel Diseases, Male, Middle Aged, Mucins, Muscle Proteins, Peptides, Proteins, Sensitivity and Specificity, Tumor Suppressor Proteins
Research areas
ID: 47486205