Frequency of New Pulmonary Neoplasm Incidentally Detected by Computed Tomography Angiography in Acute Stroke Patients—A Single-Center Study
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Frequency of New Pulmonary Neoplasm Incidentally Detected by Computed Tomography Angiography in Acute Stroke Patients—A Single-Center Study. / Bentsen, Line; Christensen, Anders; Havsteen, Inger; Hansen, Hanne; Ovesen, Christian; Christensen, Hanne.
In: Journal of Stroke & Cerebrovascular Diseases, Vol. 24, No. 5, 05.2015, p. 1008-12.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Frequency of New Pulmonary Neoplasm Incidentally Detected by Computed Tomography Angiography in Acute Stroke Patients—A Single-Center Study
AU - Bentsen, Line
AU - Christensen, Anders
AU - Havsteen, Inger
AU - Hansen, Hanne
AU - Ovesen, Christian
AU - Christensen, Hanne
N1 - Copyright © 2015 National Stroke Association. Published by Elsevier Inc. All rights reserved.
PY - 2015/5
Y1 - 2015/5
N2 - BACKGROUND: Incidental findings of suspect lung opacities are common in computed tomography (CT)-based thorax examinations, especially in high-risk patients, such as stroke patients. Screening with CT of the thorax has detected lung cancer in approximately .31%-1.20% of high-risk populations. The aim of the present study was to report the frequency of suspect lung opacities on routine acute stroke imaging.METHODS: Seven hundred and fifty-seven consecutive stroke patients evaluated for intravenous thrombolysis treatment within 4.5 hours of symptom debut, from June 2009 to December 2011, were included in a prospective registry on which this analysis was based. On admission, CT angiography from the aortic arch to vertex was performed, including the lung apices, corresponding to 1/3 of the total lung volume. A senior neuroradiologist reviewed all scans registering suspect lung opacities, which subsequently were characterized as either malignant, presumed malignant, presumed benign or benign, based on radiologic parameters of malignancy, positron emission tomography scan, histology, and clinical features.RESULTS: Suspect lung opacities appeared on the CT angiography in 20 patients (2.6%). Five suspect lung opacities were categorized as malignant and 3 suspect lung opacities were categorized as presumed malignant. This corresponds to an incidence of 1.1% (8 of 750).CONCLUSIONS: Malignant lung opacities were found in approximately 1% of this high-risk population, whereas our findings do not support full CT of the thorax as routine on stroke patients.
AB - BACKGROUND: Incidental findings of suspect lung opacities are common in computed tomography (CT)-based thorax examinations, especially in high-risk patients, such as stroke patients. Screening with CT of the thorax has detected lung cancer in approximately .31%-1.20% of high-risk populations. The aim of the present study was to report the frequency of suspect lung opacities on routine acute stroke imaging.METHODS: Seven hundred and fifty-seven consecutive stroke patients evaluated for intravenous thrombolysis treatment within 4.5 hours of symptom debut, from June 2009 to December 2011, were included in a prospective registry on which this analysis was based. On admission, CT angiography from the aortic arch to vertex was performed, including the lung apices, corresponding to 1/3 of the total lung volume. A senior neuroradiologist reviewed all scans registering suspect lung opacities, which subsequently were characterized as either malignant, presumed malignant, presumed benign or benign, based on radiologic parameters of malignancy, positron emission tomography scan, histology, and clinical features.RESULTS: Suspect lung opacities appeared on the CT angiography in 20 patients (2.6%). Five suspect lung opacities were categorized as malignant and 3 suspect lung opacities were categorized as presumed malignant. This corresponds to an incidence of 1.1% (8 of 750).CONCLUSIONS: Malignant lung opacities were found in approximately 1% of this high-risk population, whereas our findings do not support full CT of the thorax as routine on stroke patients.
KW - Aged
KW - Aged, 80 and over
KW - Female
KW - Humans
KW - Incidence
KW - Lung Neoplasms
KW - Male
KW - Middle Aged
KW - Retrospective Studies
KW - Statistics, Nonparametric
KW - Stroke
KW - Tomography, X-Ray Computed
U2 - 10.1016/j.jstrokecerebrovasdis.2014.12.025
DO - 10.1016/j.jstrokecerebrovasdis.2014.12.025
M3 - Journal article
C2 - 25817618
VL - 24
SP - 1008
EP - 1012
JO - Journal of Stroke & Cerebrovascular Diseases
JF - Journal of Stroke & Cerebrovascular Diseases
SN - 1052-3057
IS - 5
ER -
ID: 161418741