Excessive nodular hyperplasia of brunner glands associated with gastric hypersecretion and lipomatous atrophy of the pancreas
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Excessive nodular hyperplasia of brunner glands associated with gastric hypersecretion and lipomatous atrophy of the pancreas. / Toøttrup, A.; Rokkjær, M.; Kruse, A.; Poulsen, S. Seier; Jacobsen, N. O.
In: Scandinavian Journal of Gastroenterology, Vol. 34, No. 5, 13.07.1999, p. 541-544.Research output: Contribution to journal › Journal article › Research › peer-review
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T1 - Excessive nodular hyperplasia of brunner glands associated with gastric hypersecretion and lipomatous atrophy of the pancreas
AU - Toøttrup, A.
AU - Rokkjær, M.
AU - Kruse, A.
AU - Poulsen, S. Seier
AU - Jacobsen, N. O.
PY - 1999/7/13
Y1 - 1999/7/13
N2 - The case of a 34-year-old woman complaining of diarrhoea and abdominal pain is presented. Contrast radiography and endoscopy showed multiple polypoid tumours in the second part of the duodenum. Moreover, a severe fatty infiltration of the pancreas was shown by magnetic resonance and computed tomography scans. Due to pain, pancreatoduodenectomy (Whipple operation) was performed, and subsequent histopathologic examinations showed excessive Brunner gland hyperplasia of the duodenum and severe lipomatous atrophy of the pancreas. The occurrence of these two rare conditions in one patient has not been described previously, and it is conceivable that the lipomatous atrophy and exocrine insufficiency of the pancreas may have caused a compensatory stimulation of the submucosal structures of the duodenum.
AB - The case of a 34-year-old woman complaining of diarrhoea and abdominal pain is presented. Contrast radiography and endoscopy showed multiple polypoid tumours in the second part of the duodenum. Moreover, a severe fatty infiltration of the pancreas was shown by magnetic resonance and computed tomography scans. Due to pain, pancreatoduodenectomy (Whipple operation) was performed, and subsequent histopathologic examinations showed excessive Brunner gland hyperplasia of the duodenum and severe lipomatous atrophy of the pancreas. The occurrence of these two rare conditions in one patient has not been described previously, and it is conceivable that the lipomatous atrophy and exocrine insufficiency of the pancreas may have caused a compensatory stimulation of the submucosal structures of the duodenum.
KW - Diarrhoea
KW - Duodenal mucosa
KW - Malabsorption
KW - Pancreatic secretion
KW - Pathophysiology of the pancreas
UR - http://www.scopus.com/inward/record.url?scp=18344412743&partnerID=8YFLogxK
U2 - 10.1080/003655299750026317
DO - 10.1080/003655299750026317
M3 - Journal article
C2 - 10423074
AN - SCOPUS:18344412743
VL - 34
SP - 541
EP - 544
JO - Scandinavian Journal of Gastroenterology. Supplement
JF - Scandinavian Journal of Gastroenterology. Supplement
SN - 0085-5928
IS - 5
ER -
ID: 199324213