Embolization of the middle meningeal artery in patients with chronic subdural hematoma-a systematic review and meta-analysis

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Standard

Embolization of the middle meningeal artery in patients with chronic subdural hematoma-a systematic review and meta-analysis. / Haldrup, Mette; Ketharanathan, Baskaran; Debrabant, Birgit; Schwartz, Ole Sondergaard; Mikkelsen, Ronni; Fugleholm, Kare; Poulsen, Frantz Rom; Jensen, Thorbjorn Soren Ronn; Thaarup, Laerke Velia; Bergholt, Bo.

In: Acta Neurochirurgica, Vol. 162, 2020, p. 777-784.

Research output: Contribution to journalReviewResearchpeer-review

Harvard

Haldrup, M, Ketharanathan, B, Debrabant, B, Schwartz, OS, Mikkelsen, R, Fugleholm, K, Poulsen, FR, Jensen, TSR, Thaarup, LV & Bergholt, B 2020, 'Embolization of the middle meningeal artery in patients with chronic subdural hematoma-a systematic review and meta-analysis', Acta Neurochirurgica, vol. 162, pp. 777-784. https://doi.org/10.1007/s00701-020-04266-0

APA

Haldrup, M., Ketharanathan, B., Debrabant, B., Schwartz, O. S., Mikkelsen, R., Fugleholm, K., Poulsen, F. R., Jensen, T. S. R., Thaarup, L. V., & Bergholt, B. (2020). Embolization of the middle meningeal artery in patients with chronic subdural hematoma-a systematic review and meta-analysis. Acta Neurochirurgica, 162, 777-784. https://doi.org/10.1007/s00701-020-04266-0

Vancouver

Haldrup M, Ketharanathan B, Debrabant B, Schwartz OS, Mikkelsen R, Fugleholm K et al. Embolization of the middle meningeal artery in patients with chronic subdural hematoma-a systematic review and meta-analysis. Acta Neurochirurgica. 2020;162:777-784. https://doi.org/10.1007/s00701-020-04266-0

Author

Haldrup, Mette ; Ketharanathan, Baskaran ; Debrabant, Birgit ; Schwartz, Ole Sondergaard ; Mikkelsen, Ronni ; Fugleholm, Kare ; Poulsen, Frantz Rom ; Jensen, Thorbjorn Soren Ronn ; Thaarup, Laerke Velia ; Bergholt, Bo. / Embolization of the middle meningeal artery in patients with chronic subdural hematoma-a systematic review and meta-analysis. In: Acta Neurochirurgica. 2020 ; Vol. 162. pp. 777-784.

Bibtex

@article{e11c8ac3f58947c2a7b95ea87439d3c5,
title = "Embolization of the middle meningeal artery in patients with chronic subdural hematoma-a systematic review and meta-analysis",
abstract = "Background Chronic subdural hematoma (CSDH) remains a neurosurgical condition with high recurrence rate after surgical treatment. The primary pathological mechanism is considered to be repeated microbleedings from fragile neo-vessels within the outer hematoma membrane. The neo-vessels are supplied from peripheral branches of the middle meningeal artery, and embolization of MMA (eMMA) has been performed to prevent re-bleeding episodes and thereby CSDH recurrence. Objective To evaluate the published evidence for the effect of eMMA in patients with recurrent CSDH. Secondarily, to investigate the effect of eMMA as an alternative to surgery for primary treatment of CSDH. Method A systematic review of the literature on eMMA in patients with recurrent CSDH was conducted. PubMed, Embase, and Cochrane databases were reviewed using the search terms: Embolization, Medial Meningeal Artery, Chronic Subdural Haematoma, and Recurrence. Furthermore, the following mesh terms were used: Chronic Subdural Haematoma AND embolization AND medial meningeal artery AND recurrence. Eighteen papers were found and included. No papers were excluded. The number of patients with primary CSDH and the number of patients with recurrent CSDH treated with eMMA were listed. Furthermore, the number of recurrences in both categories was registered. Results Eighteen papers with a total of 191 included patients diagnosed with CSDH treated with eMMA for primary and recurrent CSDH were identified. Recurrence rate for patients treated with eMMA for recurrent CSDH was found to be 2.4%, 95% CI (0.5%; 11.0%), whereas the recurrence rate for patients treated with eMMA for primary CSDH was 4.1%, 95% CI (1.4%; 11.4%). Conclusion eMMA is a minimally invasive procedure for treatment of CSDH. Although this study is limited by publication bias, it seems that this procedure may reduce recurrence rates compared with burr hole craniostomy for both primary and recurrent hematomas. A controlled study is warranted.",
keywords = "Chronic subdural hematoma, Embolization, Medial meningeal artery, Burr hole, Craniotomy, Recurrence rate, Meta-analysis, INDEPENDENT PREDICTORS, RECURRENCE",
author = "Mette Haldrup and Baskaran Ketharanathan and Birgit Debrabant and Schwartz, {Ole Sondergaard} and Ronni Mikkelsen and Kare Fugleholm and Poulsen, {Frantz Rom} and Jensen, {Thorbjorn Soren Ronn} and Thaarup, {Laerke Velia} and Bo Bergholt",
year = "2020",
doi = "10.1007/s00701-020-04266-0",
language = "English",
volume = "162",
pages = "777--784",
journal = "Acta Neurochirurgica",
issn = "0001-6268",
publisher = "Springer Wien",

}

RIS

TY - JOUR

T1 - Embolization of the middle meningeal artery in patients with chronic subdural hematoma-a systematic review and meta-analysis

AU - Haldrup, Mette

AU - Ketharanathan, Baskaran

AU - Debrabant, Birgit

AU - Schwartz, Ole Sondergaard

AU - Mikkelsen, Ronni

AU - Fugleholm, Kare

AU - Poulsen, Frantz Rom

AU - Jensen, Thorbjorn Soren Ronn

AU - Thaarup, Laerke Velia

AU - Bergholt, Bo

PY - 2020

Y1 - 2020

N2 - Background Chronic subdural hematoma (CSDH) remains a neurosurgical condition with high recurrence rate after surgical treatment. The primary pathological mechanism is considered to be repeated microbleedings from fragile neo-vessels within the outer hematoma membrane. The neo-vessels are supplied from peripheral branches of the middle meningeal artery, and embolization of MMA (eMMA) has been performed to prevent re-bleeding episodes and thereby CSDH recurrence. Objective To evaluate the published evidence for the effect of eMMA in patients with recurrent CSDH. Secondarily, to investigate the effect of eMMA as an alternative to surgery for primary treatment of CSDH. Method A systematic review of the literature on eMMA in patients with recurrent CSDH was conducted. PubMed, Embase, and Cochrane databases were reviewed using the search terms: Embolization, Medial Meningeal Artery, Chronic Subdural Haematoma, and Recurrence. Furthermore, the following mesh terms were used: Chronic Subdural Haematoma AND embolization AND medial meningeal artery AND recurrence. Eighteen papers were found and included. No papers were excluded. The number of patients with primary CSDH and the number of patients with recurrent CSDH treated with eMMA were listed. Furthermore, the number of recurrences in both categories was registered. Results Eighteen papers with a total of 191 included patients diagnosed with CSDH treated with eMMA for primary and recurrent CSDH were identified. Recurrence rate for patients treated with eMMA for recurrent CSDH was found to be 2.4%, 95% CI (0.5%; 11.0%), whereas the recurrence rate for patients treated with eMMA for primary CSDH was 4.1%, 95% CI (1.4%; 11.4%). Conclusion eMMA is a minimally invasive procedure for treatment of CSDH. Although this study is limited by publication bias, it seems that this procedure may reduce recurrence rates compared with burr hole craniostomy for both primary and recurrent hematomas. A controlled study is warranted.

AB - Background Chronic subdural hematoma (CSDH) remains a neurosurgical condition with high recurrence rate after surgical treatment. The primary pathological mechanism is considered to be repeated microbleedings from fragile neo-vessels within the outer hematoma membrane. The neo-vessels are supplied from peripheral branches of the middle meningeal artery, and embolization of MMA (eMMA) has been performed to prevent re-bleeding episodes and thereby CSDH recurrence. Objective To evaluate the published evidence for the effect of eMMA in patients with recurrent CSDH. Secondarily, to investigate the effect of eMMA as an alternative to surgery for primary treatment of CSDH. Method A systematic review of the literature on eMMA in patients with recurrent CSDH was conducted. PubMed, Embase, and Cochrane databases were reviewed using the search terms: Embolization, Medial Meningeal Artery, Chronic Subdural Haematoma, and Recurrence. Furthermore, the following mesh terms were used: Chronic Subdural Haematoma AND embolization AND medial meningeal artery AND recurrence. Eighteen papers were found and included. No papers were excluded. The number of patients with primary CSDH and the number of patients with recurrent CSDH treated with eMMA were listed. Furthermore, the number of recurrences in both categories was registered. Results Eighteen papers with a total of 191 included patients diagnosed with CSDH treated with eMMA for primary and recurrent CSDH were identified. Recurrence rate for patients treated with eMMA for recurrent CSDH was found to be 2.4%, 95% CI (0.5%; 11.0%), whereas the recurrence rate for patients treated with eMMA for primary CSDH was 4.1%, 95% CI (1.4%; 11.4%). Conclusion eMMA is a minimally invasive procedure for treatment of CSDH. Although this study is limited by publication bias, it seems that this procedure may reduce recurrence rates compared with burr hole craniostomy for both primary and recurrent hematomas. A controlled study is warranted.

KW - Chronic subdural hematoma

KW - Embolization

KW - Medial meningeal artery

KW - Burr hole

KW - Craniotomy

KW - Recurrence rate

KW - Meta-analysis

KW - INDEPENDENT PREDICTORS

KW - RECURRENCE

U2 - 10.1007/s00701-020-04266-0

DO - 10.1007/s00701-020-04266-0

M3 - Review

C2 - 32086603

VL - 162

SP - 777

EP - 784

JO - Acta Neurochirurgica

JF - Acta Neurochirurgica

SN - 0001-6268

ER -

ID: 252727324