Ulrike Leurs
Ulrike Leurs

Academic employee


  1. 2011
  2. Efficient synthesis of an (aminooxy) acetylated-somatostatin derivative using (aminooxy)acetic acid as a 'carbonyl capture' reagent

    Mezö, G., Szabó, I., Kertész, I., Hegedüs, R., Orbán, E., Leurs, Ulrike, Bösze, S., Halmos, G. & Manea, M., Jan 2011, In : Journal of Peptide Science. 17, 1, p. 39-46 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Enhanced enzymatic stability and antitumor activity of daunorubicin-GnRH-III bioconjugates modified in position 4

    Manea, M., Leurs, Ulrike, Orbán, E., Baranyai, Z., Öhlschläger, P., Marquardt, A., Schulcz, Á., Tejeda, M., Kapuvári, B., Tóvári, J. & Mezo, G., 20 Jul 2011, In : Bioconjugate Chemistry. 22, 7, p. 1320-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2012
  5. Design, synthesis, in vitro stability and cytostatic effect of multifunctional anticancer drug-bioconjugates containing GnRH-III as a targeting moiety

    Leurs, Ulrike, Mező, G., Orbán, E., Ohlschläger, P., Marquardt, A. & Manea, M., 2012, In : Biopolymers. 98, 1, p. 1-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. GnRH-III based multifunctional drug delivery systems containing daunorubicin and methotrexate

    Leurs, Ulrike, Lajkó, E., Mező, G., Orbán, E., Öhlschläger, P., Marquardt, A., Kőhidai, L. & Manea, M., Jun 2012, In : European Journal of Medicinal Chemistry. 52, p. 173-83 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Inhibitor scaffold for the histone lysine demethylase KDM4C (JMJD2C)

    Leurs, Ulrike, Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Lohse, Brian, 15 Sep 2012, In : Bioorganic & Medicinal Chemistry Letters. 22, 18, p. 5811-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2013
  9. Published

    Posttranslational Modifications of the Histone 3 Tail and Their Impact on the Activity of Histone Lysine Demethylases In Vitro

    Lohse, Brian, Helgstrand, C., Andersson, J. L., Leurs, Ulrike, Cloos, Paul, Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 2 Jul 2013, In : P L o S One. 8, 7, p. e67653

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2014
  11. Published

    Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

    Leurs, Ulrike, Lohse, Brian, Rand, Kasper Dyrberg, Ming, S., Riise, E. S., Cole, P. A., Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 11 Jul 2014, In : A C S Chemical Biology. 9, 9, p. 2131-2138 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Design and Synthesis of Epigenetic Drugs: Targeting the Histone Demethylase KDM4C

    Leurs, Ulrike, 27 Sep 2014, 136 p.

    Research output: Book/ReportPh.D. thesis

  13. Published

    Dissecting the Binding Mode of Low Affinity Phage Display Peptide Ligands to Protein Targets by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry

    Leurs, Ulrike, Lohse, Brian, Ming, S. A., Cole, P. A., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Rand, Kasper Dyrberg, 17 Oct 2014, In : Analytical Chemistry. 86, 23, p. 11734-11741 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2015
  15. Published

    Getting to the core of protein pharmaceuticals – comprehensive structure analysis by mass spectrometry

    Leurs, Ulrike, Mistarz, U. H. & Rand, Kasper Dyrberg, 2015, In : European Journal of Pharmaceutics and Biopharmaceutics. 93, p. 95-109 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Charting the interactome of PDE3A in human cells using an IBMX based chemical proteomics approach

    Corradini, E., Klaasse, G., Leurs, Ulrike, Heck, A. J. R., Martin, N. I. & Scholten, A., Oct 2015, In : Molecular BioSystems. 11, 10, p. 2786-97 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2016
  18. Published

    Analytical Techniques in the Pharmaceutical Sciences

    Leurs, Ulrike, Mistarz, U. H. & Rand, Kasper Dyrberg, 2016, Analytical Techniques in the Pharmaceutical Sciences. Müllertz, A., Perrie, Y. & Rades, T. (eds.). Springer Publishing Company, p. 253-289 36 p. (Advances in Delivery Science and Technology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  19. Published

    The Impact of the ‘Austrian’ Mutation of the Amyloid Precursor Protein Transmembrane Helix is Communicated to the Hinge Region

    Stelzer, W., Scharnagl, C., Leurs, Ulrike, Rand, Kasper Dyrberg & Langosch, D., 2016, In : ChemistrySelect. 1, 15, p. 4408-4412 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Synthesis and characterisation of substrate-based peptides as inhibitors of histone demethylase KDM4C

    Nielsen, S. D., Leurs, Ulrike, Bergner, M., Barris, S. A., Devkota, K., Meyer, K., Iaria, D., McCaughan, J., Lohse, Brian, Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 13 Jun 2016, In : Protein and Peptide Letters. 23, 9, p. 772 - 776 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2017
  22. Published

    Mapping the interactions of selective biochemical probes of antibody conformation by hydrogen-deuterium exchange mass spectrometry

    Leurs, Ulrike, Beck, H., Bonnington, L., Lindner, I., Pol, E. & Rand, Kasper Dyrberg, 1 Jun 2017, In : ChemBioChem. 18, 11, p. 1016-1021

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2019
  24. Published

    Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab fragment of NISTmAb

    Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Filliben, J. J., Huang, R. Y., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H., Walters, B. T., Zhang, J., Venable, J. D., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R. K., Chandramohan, A., Anand, G. S., Nirudodhi, S. N., Sperry, J. B., Rouse, J. C., Carroll, J. A., Rand, Kasper Dyrberg, Leurs, Ulrike, Weis, D. D., Al-Naqshabandi, M. A., Hageman, T. S., Deredge, D., Wintrode, P. L., Papanastasiou, M., Lambris, J. D., Li, S. & Urata, S., 2019, In : Analytical Chemistry. 91, 11, p. 7336-7345

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Centroid Data Measured between 3.6 degrees C and 25.4 degrees C for the Fab Fragment of NISTmAb

    Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Huang, R. Y., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H., Walters, B. T., Zhang, J., Venable, J., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R., Chandramohan, A., Anand, G. S., Nirudodhi, S. N., Sperry, J. B., Rouse, J. C., Carroll, J. A., Rand, Kasper Dyrberg, Leurs, Ulrike, Weis, D. D., Al-Naqshabandi, M. A., Hageman, T. S., Deredge, D., Wintrode, P. L., Papanastasiou, M., Lambris, J. D., Li, S. & Urata, S., 2 May 2019, In : Journal of Research of the National Institute of Standards and Technology. 124, 7 p., 124009.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 34256647