Søren-Peter Olesen

Søren-Peter Olesen

Professor


  1. Published

    Molecular and functional characterization of Kv 7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats

    Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter, Greenwood, I. A. & Dalsgaard, T., May 2016, In: British Journal of Pharmacology. 173, 9, p. 1478-1490 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Mutations in sodium channel {beta}-subunit SCN3B are associated with early-onset lone atrial fibrillation

    Olesen, M. S., Jespersen, Thomas, Nielsen, J. B., Liang, B., Møller, D. V., Hedley, P., Christiansen, M., Varro, A., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole & Svendsen, Jesper Hastrup, 2011, In: Cardiovascular Research. 89, 4, p. 786-793 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Mutations in the Kv1.5 channel gene KCNA5 in cardiac arrest patients.

    Nielsen, N. H., Winkel, B. G., Kanters, Jørgen K., Schmitt, Nicole, Hofman-Bang, J., Jensen, H. S., Bentzen, Bo Hjorth, Sigurd, B., Larsen, Lars Allan, Andersen, P. S., Kjeldsen, K., Grunnet, Morten, Christiansen, M., Olesen, Søren-Peter & Haunsø, Stig, 2007, In: Biochemical and Biophysical Research Communications. 354, 3, p. 776-82 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Myocardial structural, contractile and electrophysiological changes in the guinea-pig heart failure model induced by chronic sympathetic activation

    Soltysinska, E., Osadchiy, O. & Olesen, Søren-Peter, 2011, In: Experimental Physiology. 96, 7, p. 647-63 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    NS19504: a novel BK channel activator with relaxing effect on bladder smooth muscle spontaneous phasic contractions

    Nausch, B., Rode, F., Jørgensen, S., Nardi, A., Korsgaard, M. P. G., Hougaard, C., Bonev, A. D., Brown, W. D., Dyhring, T., Strøbæk, D., Olesen, Søren-Peter, Christophersen, P., Grunnet, M., Nelson, M. T. & Rønn, L. C. B., Sep 2014, In: Journal of Pharmacology and Experimental Therapeutics. 350, 3, p. 520-30 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1.

    Korolkova, Y. V., Bocharov, E. V., Angelo, K., Maslennikov, I. V., Grinenko, O. V., Lipkin, A. V., Nosyreva, E. D., Pluzhnikov, K. A., Olesen, Søren-Peter, Arseniev, A. S. & Grishin, E. V., 2002, In: Journal of Biological Chemistry. 277, 45, p. 43104-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Non-invasive detection of animal nerve impulses with an atomic magnetometer operating near quantum limited sensitivity

    Jensen, K., Budvytyte, R., Thomas, Rodrigo A., Wang, T., Fuchs, A. M., Balabas, M. V., Vasilakis, G., Mosgaard, L. D., Stærkind, Hans, Müller, Jörg Helge, Heimburg, Thomas Rainer, Olesen, Søren-Peter & Polzik, Eugene Simon, 15 Jul 2016, In: Scientific Reports. 6, 29638.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published
  9. Published

    One man's side effect is another man's therapeutic opportunity: targeting Kv7 channels in smooth muscle disorders

    Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter & Greenwood, I. A., 2013, In: British Journal of Pharmacology. 168, 1, p. 19-27 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Pharmacological activation of rapid delayed rectifier potassium current suppresses bradycardia-induced triggered activity in the isolated guinea pig heart.

    Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2007, In: Journal of Pharmacology and Experimental Therapeutics. 321, 3, p. 996-1002 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Pharmacological characterization of small-conductance Ca(2+)-activated channels stably expressed in HEK 293 cells

    Strobaek, D., Jørgensen, T. D., Christophersen, P., Ahring, P. K. & Olesen, Søren-Peter, 2000, In: British Journal of Pharmacology. 129(5), p. 991-999

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Pharmacological investigation of the role of ion channels in salivary secretion.

    Stummann, T. C., Poulsen, J. H., Hay-Schmidt, Anders, Grunnet, Morten, Klærke, Dan Arne, Rasmussen, Hanne Borger, Olesen, Søren-Peter & Jorgensen, N. K., 2003, In: Pflügers Archiv: European Journal of Physiology. 446, 1, p. 78-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Phosphatidylinositol-bisphosphate regulates intercellular coupling in cardiac myocytes

    Hofgaard, J. P., Banach, K., Mollerup, S., Jørgensen, H. K., Olesen, Søren-Peter, von Holstein-Rathlou, Niels-Henrik & Nielsen, Morten Schak, 2008, In: Pflügers Archiv: European Journal of Physiology. 457, 2, p. 303-13 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Physiological consequences of transient outward K(+) current activation during heart failure in the canine left ventricle

    Cordeiro, J. M., Callø, Kirstine, Moise, N. S., Kornreich, B., Giannandrea, D., Di Diego, J. M., Olesen, Søren-Peter & Antzelevitch, C., 2012, In: Journal of Molecular and Cellular Cardiology. 52, 6, p. 1291-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2

    Grubb, Søren, Aistrup, G. L., Koivumäki, J. T., Speerschneider, T., Gottlieb, Lisa Amalie, Mutsaers, N. A. M., Olesen, Søren-Peter, Callø, Kirstine & Thomsen, Morten Bækgaard, 1 Aug 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 309, 3, p. H481-H489 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Protein kinase A stimulates Kv7.1 surface expression by regulating Nedd4-2-dependent endocytic trafficking

    Andersen, M. N., Hefting, L. L., Steffensen, Annette Buur, Schmitt, Nicole, Olesen, Søren-Peter, Olsen, Jesper Velgaard, Lundby, Alicia & Rasmussen, Hanne Borger, 15 Nov 2015, In: American Journal of Physiology: Cell Physiology. 309, 10, p. C693-C706 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation

    Ahlberg, G., Refsgaard, L., Lundegaard, Pia Rengtved, Andreasen, Laura Korsholm, Ranthe, M. F., Linscheid, N., Nielsen, J. B., Melbye, M., Haunsø, Stig, Sajadieh, Ahmad, Camp, L., Olesen, Søren-Peter, Rasmussen, Simon, Lundby, Alicia, Ellinor, P. T., Holst, A. G., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2018, In: Nature Communications. 9, 1, 11 p., 4316.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Reduced KCNQ4-encoded voltage-dependent potassium channel activity underlies impaired ß-adrenoceptor-mediated relaxation of renal arteries in hypertension

    Chadha, P. S., Zunke, F., Zhu, H., Davis, A. J., Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter, Cole, W. C., Moffatt, J. D. & Greenwood, I., 2012, In: Hypertension. 59, 4, p. 877-84 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Regulation of cloned, Ca2+-activated K+ channels by cell volume changes.

    Grunnet, Morten, MacAulay, Nanna, Jorgensen, N. K., Jensen, S., Olesen, Søren-Peter & Klærke, Dan Arne, 2002, In: Pflügers Archiv: European Journal of Physiology. 444, 1-2, p. 167-77 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment.

    Rasmussen, Hanne Borger, Frøkjær-Jensen, Christian, Jensen, C. S., Jensen, H. S., Jørgensen, N. K., Misonou, H., Trimmer, J. S., Olesen, Søren-Peter & Schmitt, Nicole, 2007, In: Journal of Cell Science. 120, Pt 6, p. 953-63 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Single-copy insertion of transgenes in Caenorhabditis elegans.

    Frøkjær-Jensen, Christian, Davis, M. W., Hopkins, C. E., Newman, B. J., Thummel, J. M., Olesen, Søren-Peter, Grunnet, Morten & Jorgensen, E. M., 2008, In: Nature Genetics. 40, 11, p. 1375-83 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Specific Sorting and Post-Golgi trafficking of Dendritic Potassium Channels in Living Neurons

    Jensen, C. S., Watanabe, S., Rasmussen, Hanne Borger, Schmitt, Nicole, Olesen, Søren-Peter, Frost, N. A., Blanpied, T. A. & Misonou, H., 25 Feb 2014, In: The Journal of Biological Chemistry. 289, p. 10566-10581 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Subcellular localization of the delayed rectifier K(+) channels KCNQ1 and ERG1 in the rat heart.

    Rasmussen, Hanne Borger, Møller, Morten, Knaus, H., Jensen, B. S., Olesen, Søren-Peter & Jørgensen, N. K., 2003, In: American Journal of Physiology: Heart and Circulatory Physiology. 286, 4, p. H1300-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Subcellular localization of the delayed rectifier potassium channel KCNQ1 and ERG1 in rat heart

    Rasmussen, H. B., Møller, M., Knaus, H. G., Jensen, B. S., Olesen, Søren-Peter & Jørgensen, N. K., 2004, In: American Journal of Physiology: Heart and Circulatory Physiology. 286, p. H1300-H1309

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Subtype-specific, bi-component inhibition of SK channels by low internal pH.

    Peitersen, T., Jespersen, Thomas, Jorgensen, N. K., Olesen, Søren-Peter & Grunnet, Morten, 2006, In: Biochemical and Biophysical Research Communications. 343, 3, p. 943-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Synthesis and characterisation of NS13558: a new important tool for addressing KCa1.1 channel function ex vivo

    Bentzen, Bo Hjorth, Andersen, R. W., Olesen, Søren-Peter, Grunnet, Morten & Nardi, A., 2009, In: NAUNYN-SCHMIEDEBERGS ARCHIV FUR EXPERIMENTELLE PATHOLOGIE UND PHARMAKOLOGIE.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    TMEM16A is implicated in the regulation of coronary flow and is altered in hypertension

    Askew Page, H. R., Dalsgaard, T., Baldwin, S. N., Jepps, Thomas Andrew Qvistgaard, Povstyan, O., Olesen, Søren-Peter & Greenwood, I. A., Jun 2019, In: British Journal of Pharmacology. 176, 11, p. 1635-1648

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

    Diness, Jonas Goldin, Skibsbye, L., Simó-Vicens, R., Louro Larupa dos Santos, J., Lundegaard, Pia Rengtved, Citerni, C., Sauter, D. R. P., Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, U. S., Jespersen, Thomas, Grunnet, Morten & Bentzen, Bo Hjorth, 10 Oct 2017, In: Circulation: Arrhythmia and Electrophysiology. 10, 19 p., e005125.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    The Ca2+-activated K+ channel of intermediate-conductance: A molecular target for novel treatments?

    Jensen Skanning, B., Strøbaek, D., Olesen, Søren-Peter & Christophersen, P., 2001, In: Current Drug Targets. 2, p. 401-422

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family.

    Jespersen, Thomas, Membrez, M., Nicolas, C. S., Pitard, B., Staub, O., Olesen, Søren-Peter, Baró, I. & Abriel, H., 2007, In: Cardiovascular Research. 74, 1, p. 64-74 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    The KCNQ1 potassium channel: from gene to physiological function.

    Jespersen, Thomas, Grunnet, Morten & Olesen, Søren-Peter, 2005, In: Physiology. 20, p. 408-16 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes.

    Jensen, H. S., Callø, Kirstine, Jespersen, Thomas, Jensen, B. S. & Olesen, Søren-Peter, 2005, In: Brain Research. 139, 1, p. 52-62 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The Phenotype Characteristics of Type-13 Long QT Syndrome with mutation in KCNJ5 (Kir3.4-G387R)

    Wang, F., Liu, J., Hong, L., Liang, B., Graff, C., Yang, Y., Christiansen, M., Olesen, Søren-Peter, Zhang, L. & Kanters, Jørgen K., Oct 2013, In: Heart rhythm : the official journal of the Heart Rhythm Society. 10, 10, p. 1500-1506 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels.

    Bentzen, Bo Hjorth, Schmitt, Nicole, Callø, Kirstine, Dalby Brown, W., Grunnet, Morten & Olesen, Søren-Peter, 2006, In: Neuropharmacology. 51, 6, p. 1068-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The case of BK channel openers

    Nardi, A., Calderone, V. & Olesen, Søren-Peter, 2006, In: Letters in Drug Design and Discovery. 3, p. 210-218

    Research output: Contribution to journalJournal articleResearch

  36. Published

    The corticosteroid hormone induced factor: a new modulator of KCNQ1 channels?

    Jespersen, Thomas, Grunnet, Morten, Rasmussen, Hanne Borger, Jørgensen, N. B., Jensen, H., Angelo, K., Olesen, Søren-Peter & Klærke, Dan Arne, 2006, In: Biochemical and Biophysical Research Communications. 341, 4, p. 979-88 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The genetic component of Brugada syndrome

    Nielsen, M. W., Holst, A. G., Olesen, Søren-Peter & Olesen, Morten Steen Salling, 2013, In: Frontiers in Physiology. 4, p. 179

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The genetic component of Brugada syndrome

    Nielsen, M. W., Holst, A. G., Olesen, Søren-Peter & Olesen, Morten Steen Salling, 2013, In: Frontiers in Physiology. 4, p. 179

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The role og K+ and C1- channels in salivary secretion

    Stummann, T. C., Poulsen, J. H., Hay-Schmidt, Anders, Grunnet, Morten, Klærke, Dan Arne, Olesen, Søren-Peter & Jørgensen, N. K., 2003, In: Pflügers Archiv: European Journal of Physiology. 446, p. 78-87

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels.

    Bentzen, Bo Hjorth, Nardi, A., Callø, Kirstine, Madsen, L. S., Olesen, Søren-Peter & Grunnet, Morten, 2007, In: Molecular Pharmacology. 72, 4, p. 1033-44 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size

    Christensen, A. H., Chatelain, F. C., Huttner, I. G., Olesen, Morten Steen Salling, Soka, M., Feliciangeli, S., Horvat, C., Santiago, C. F., Vandenberg, J. I., Schmitt, Nicole, Olesen, Søren-Peter, Lesage, F. & Fatkin, D., Aug 2016, In: Journal of Molecular and Cellular Cardiology. 97, p. 24-35 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Tissue-specific effects of acetylcholine in the canine heart

    Callø, Kirstine, Goodrow, R., Olesen, Søren-Peter, Antzelevitch, C. & Cordeiro, J. M., 2013, In: A J P: Heart and Circulatory Physiology (Online). 305, p. H66-H75 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Trafficking of Kv2.1 Channels to the Axon Initial Segment by a Novel Nonconventional Secretory Pathway

    Jensen, C. S., Watanabe, S., Stas, J. I., Klaphaak, J., Yamane, A., Schmitt, Nicole, Olesen, Søren-Peter, Trimmer, J. S., Rasmussen, Hanne Borger & Misonou, H., 29 Nov 2017, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 37, 48, p. 11523-11536 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Trafficking of the IKs -Complex in MDCK Cells: Site of Subunit Assembly and Determinants of Polarized Localization

    David, J., Andersen, M. N., Olesen, Søren-Peter, Rasmussen, Hanne Borger & Schmitt, Nicole, Apr 2013, In: Traffic. 14, 4, p. 399-411 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts

    Soltysinska, E., Olesen, Søren-Peter, Christ, T., Wettwer, E., Varró, A., Grunnet, Morten & Jespersen, Thomas, 2009, In: Pflügers Archiv: European Journal of Physiology. 459, 1, p. 11-23 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Unique binding site on the molecular scaffold of scorpion toxin BeKm-1 provides selectivity for HERG potassium channels

    Korolkova, Y. V., Bocharov, E. V., Pedersen, K. A., Maslennikov, I. V., Grinenko, O. V., Lipkin, A. V., Nosireva, E. D., Pluzhnikov, K. A., Olesen, Søren-Peter, Arseniev, A. S. & Grishin, E. V., 2002, In: Journal of Biological Chemistry. 277, p. 43104-43109

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Vascular smooth muscle contraction is an independent regulator of endothelial nitric oxide production

    Bang, L., Nielsen-Kudsk, J. E., Gruhn, N., Theilgaard, S. A., Olesen, Søren-Peter & Aldershvile, J., 1999, In: Scandinavian Cardiovascular Journal. 33, p. 71-78

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Ventricular repolarization time, location of pacing stimulus and current pulse amplitude conspire to determine arrhythmogenicity in mice

    Speerschneider, T., Grubb, Søren, Olesen, Søren-Peter, Callø, Kirstine & Thomsen, Morten Bækgaard, 9 Feb 2017, In: Acta Physiologica. 219, 3, p. 662-670 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Ventricular tachycardia in an Brugada syndrome patient caused by novel deletion mutation in SCN5A

    Tfelt-Hansen, Jacob, Jespersen, T., Hofman-Bang, J., Rasmussen, H., Cedergreen, P. K., Skovby, F., Abriel, H., Svendsen, J., Olesen, Søren-Peter & Christiansen & Haunso, S., 2009, In: Canadian Journal of Cardiology. 25, 3

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Very early-onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation

    Olesen, Morten Steen Salling, Andreasen, Laura Korsholm, Jabbari, J., Refsgaard, L., Haunsø, Stig, Olesen, Søren-Peter, Nielsen, J. B., Schmitt, Nicole & Svendsen, Jesper Hastrup, Feb 2014, In: Heart Rhythm. 11, 2, p. 246-251 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Voltage-independent KCNQ4 currents induced by (+/-)BMS-204352.

    Schrøder, R. L., Strøbaek, D., Olesen, Søren-Peter & Christophersen, P., 2003, In: Pflügers Archiv: European Journal of Physiology. 446, 5, p. 607-16 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    hKCNE4 inhibits the hKCNQ1 potassium current without affecting the activation kinetics.

    Grunnet, Morten, Olesen, Søren-Peter, Klærke, Dan Arne & Jespersen, Thomas, 2005, In: Biochemical and Biophysical Research Communications. 328, 4, p. 1146-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts

    Skarsfeldt, M. A., Jepps, Thomas Andrew Qvistgaard, Bomholtz, Sofia Hammami, Abildgaard, L., Sørensen, U. S., Gregers, E., Svendsen, Jesper Hastrup, Diness, J. G., Grunnet, M., Schmitt, Nicole, Olesen, Søren-Peter & Bentzen, Bo Hjorth, Apr 2016, In: Pfluegers Archiv. 468, 4, p. 643-654 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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