Lykke Sylow
Associate Professor - Promotion Programme
Molecular Metabolism in Cancer and Ageing
Blegdamsvej 3
2200 København N
- 2023
- Published
Adenosine monophosphate-activated protein kinase is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
Raun, Steffen Henning, Ali, Mona Sadek, Han, X., Henriquez-Olguín, Carlos, Pham, Tang Cam Phung, Meneses Valdés, Roberto Andrés, Knudsen, Jonas Roland, Willemsen, A. C. H., Larsen, Steen, Jensen, Thomas Elbenhardt, Langen, R. & Sylow, Lykke, 2023, In: Journal of Cachexia, Sarcopenia and Muscle. 14, 4, p. 1631-1647Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disruption of mitochondrial dynamics triggers muscle inflammation through interorganellar contacts and mitochondrial DNA mislocation
Irazoki, Andrea, Gordaliza-Alaguero, I., Frank, E., Giakoumakis, N. N., Seco, J., Palacín, M., Gumà, A., Sylow, Lykke, Sebastián, D. & Zorzano, A., 2023, In: Nature Communications. 14, 1, 19 p., 108.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance in patients with cancer: a systematic review and meta-analysis
Màrmol, J. M., Carlsson, Michala, Raun, Steffen Henning, Grand, Mia Klinten, Sørensen, Jonas, Lang Lehrskov, L., Richter, Erik A., Norgaard, O. & Sylow, Lykke, 2023, In: Acta Oncologica. 62, 4, p. 364-371Research output: Contribution to journal › Review › Research › peer-review
- Published
NOX2 deficiency exacerbates diet-induced obesity and impairs molecular training adaptations in skeletal muscle
Henriquez-Olguín, Carlos, Meneses Valdés, Roberto Andrés, Raun, Steffen Henning, Gallero, S., Knudsen, Jonas Roland, Li, Z., Li, J., Sylow, Lykke, Jaimovich, E. & Jensen, Thomas Elbenhardt, 2023, In: Redox Biology. 65, 12 p., 102842.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TNIK is a conserved regulator of glucose and lipid metabolism in obesity
Pham, Tang Cam Phung, Dollet, L., Ali, Mona Sadek, Raun, Steffen Henning, Møller, Lisbeth L V, Jafari Kermani, Abbas, Ditzel, N., Andersen, Nicoline Resen, Fritzen, Andreas Mæchel, Gerhart-Hines, Zach, Kiens, Bente, Suomalainen, A., Simpson, S. J., Salling Olsen, M., Kieser, A., Schjerling, Peter, Nieminen, A. I., Richter, Erik A., Havula, E. & Sylow, Lykke, 2023, In: Science Advances. 9, 32, 18 p., eadf7119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action
Møller, Lisbeth L V, Ali, Mona Sadek, Davey, J., Raun, Steffen Henning, Andersen, Nicoline Resen, Long, J. Z., Qian, H., Jeppesen, J. F., Henriquez-Olguín, Carlos, Frank, E., Jensen, Thomas Elbenhardt, Højlund, K., Wojtaszewski, Jørgen F P, Nielsen, J., Chiu, T. T., Jedrychowski, M. P., Gregorevic, P., Klip, A., Richter, Erik A. & Sylow, Lykke, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 27, 12 p., e2211041120.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
Raun, Steffen Henning, Ali, Mona Sadek, Han, X., Henriquez-Olguín, Carlos, Pham, Tang Cam Phung, Knudsen, Jonas Roland, Willemsen, A. C. H., Larsen, S., Jensen, Thomas Elbenhardt, Langen, R. & Sylow, Lykke, 7 Jun 2022, bioRxiv, 37 p.Research output: Working paper › Preprint › Research
- Published
Cancer causes dysfunctional insulin signaling and glucose transport in a muscle-type-specific manner
Raun, Steffen Henning, Knudsen, Jonas Roland, Han, X., Jensen, Thomas Elbenhardt & Sylow, Lykke, 2022, In: F A S E B Journal. 36, 3, 16 p., e22211.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise increases phosphorylation of the putative mTORC2 activity readout NDRG1 in human skeletal muscle
Knudsen, Jonas Roland, Persson, Kaspar Wredstrøm, Meister, J., Carl, Christian Strini, Raun, Steffen Henning, Andersen, Nicoline Resen, Sylow, Lykke, Kiens, Bente, Jensen, Thomas Elbenhardt, Richter, Erik A. & Kleinert, Maximilian, 2022, In: American Journal of Physiology: Endocrinology and Metabolism. 322, 1, p. E63-E73 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation of macronutrient tolerance in Drosophila melanogaster
Havula, E., Ghazanfar, S., Lamichane, N., Francis, D., Hasygar, K., Liu, Y., Alton, L. A., Johnstone, J., Needham, E. J., Pulpitel, T., Clark, T., Niranjan, H. N., Shang, V., Tong, V., Jiwnani, N., Audia, G., Alves, A. N., Sylow, L., Mirth, C., Neely, G. G. & 4 others, , 2022, In: Nature Communications. 13, 16 p., 1637.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incidence of new-onset type 2 diabetes after cancer: A Danish cohort study
Sylow, Lykke, Grand, Mia Klinten, von Heymann, A., Persson, F., Siersma, Volkert Dirk, Kriegbaum, Margit, Andersen, Christen Bertel L & Johansen, Christoffer, 2022, In: Diabetes Care. 45, 6, p. e105-e106 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Involvement of the extracellular matrix and integrin signalling proteins in skeletal muscle glucose uptake
Draicchio, F., Behrends, V., Tillin, N. A., Hurren, N. M., Sylow, Lykke & Mackenzie, R., 2022, In: Journal of Physiology. 600, 20, p. 4393-4408 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Measurement of skeletal muscle glucose uptake in mice in response to acute treadmill running
Møller, Lisbeth L V, Raun, Steffen Henning, Fritzen, Andreas Mæchel & Sylow, Lykke, 2022, In: Journal of Biological Methods. 9, 3, 13 p., e162.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Editorial: Skeletal muscle immunometabolism
Trollet, C., Cheng, A. J., Sylow, Lykke, Batista, M. L. & Pillon, N. J., 2021, In: Frontiers in Physiology. 12, 3 p., 683088.Research output: Contribution to journal › Editorial › Research
- Published
Effect of hypoxic exercise on glucose tolerance in healthy and pre-diabetic adults
De Groote, E., Britto, F. A., Balan, E., Warnier, G., Thissen, J., Nielens, H., Sylow, Lykke & Deldicque, L., 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, 1, p. E43-E54 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Roux-en-Y gastric bypass on circulating follistatin, activin A, and peripheral ActRIIB signaling in humans with obesity and type 2 diabetes
Pham, Tang Cam Phung, Bojsen-Møller, K. N., Madsbad, Sten, Wojtaszewski, Jørgen F P, Richter, Erik A. & Sylow, Lykke, 2021, In: International Journal of Obesity. 45, p. 316-325 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise - a panacea of metabolic dysregulation in cancer: Physiological and molecular insights
Raun, Steffen Henning, Buch-Larsen, K., Schwarz, Peter & Sylow, Lykke, 2021, In: International Journal of Molecular Sciences. 22, 7, 23 p., 3469.Research output: Contribution to journal › Review › Research › peer-review
- Published
Interactions between insulin and exercise
Richter, Erik A., Sylow, Lykke & Hargreaves, M., 2021, In: Biochemical Journal. 478, 21, p. 3827-3846 20 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The many actions of insulin in skeletal muscle, the paramount tissue determining glycemia
Sylow, Lykke, Tokarz, V. L., Richter, Erik A. & Klip, A., 2021, In: Cell Metabolism. 33, 4, p. 758-780 23 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Three challenges of being a scientist in an age of misinformation
Sylow, Lykke, 2021, In: Journal of Physiology. 599, 7, p. 1937-1938 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- 2020
- Published
Conditioned media from MCF7 and BT474 breast cancer cells induce insulin resistance in skeletal muscle myotubes
Ali, Mona Sadek, Han, X., Li, J., Jäättelä, M. & Sylow, Lykke, 28 Jan 2020, bioRxiv.Research output: Working paper › Preprint › Research
- Published
Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion
Han, X., Raun, Steffen Henning, Carlsson, Michala, Sjøberg, K. A., Henriquez-Olguín, Carlos, Ali, Mona Sadek, Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Møller, Lisbeth L V, Li, Z., Li, J., Jensen, Thomas Elbenhardt, Kiens, Bente & Sylow, Lykke, 2020, In: Metabolism - Clinical and Experimental. 105, 14 p., 154169.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating follistatin and activin A and their regulation by insulin in obesity and type 2 diabetes
Sylow, Lykke, Vind, B. F., Kruse, R., Møller, P. M., Wojtaszewski, Jørgen F P, Richter, Erik A. & Højlund, K., 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 5, p. 1343-1354 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Housing temperature influences exercise training adaptations in mice
Raun, Steffen Henning, Henriquez-Olguín, Carlos, Karavaeva, Iuliia, Ali, Mona Sadek, Møller, Lisbeth L V, Kot, Witold, Castro-Mejía, J. L., Nielsen, Dennis Sandris, Gerhart-Hines, Zach, Richter, Erik A. & Sylow, Lykke, 2020, In: Nature Communications. 11, 16 p., 1560.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin-stimulated glucose uptake partly relies on p21-activated kinase (PAK)2, but not PAK1, in mouse skeletal muscle
Møller, Lisbeth L V, Jaurji, M., Kjøbsted, Rasmus, Joseph, G. A., Madsen, A. B., Knudsen, Jonas Roland, Lundsgaard, Anne-Marie, Andersen, Nicoline Resen, Schjerling, P., Jensen, Thomas Elbenhardt, Krauss, R. S., Richter, Erik A. & Sylow, Lykke, 2020, In: Journal of Physiology. 598, 23, p. 5351-5377 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 19375571
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mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
218
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Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training
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Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise
Research output: Contribution to journal › Journal article › Research › peer-review
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