Jonas Goldin Diness

Jonas Goldin Diness

Guest researcher


Publication year:
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1 - 22 out of 22Page size: 500
  1. 2024
  2. E-pub ahead of print

    A phase 1 trial of AP30663, a KCa2 channel inhibitor in development for conversion of atrial fibrillation

    Yfanti, C., Vestbjerg, B., van't Westende, J., Edvardsson, N., Monfort, L. M., Olesen, Morten Steen Salling, Bentzen, Bo Hjorth, Grunnet, Morten, Eveleens Maarse, B. C., Diness, Jonas Goldin, Kemme, M. J. B., Sørensen, U., Moerland, M., van Esdonk, M. J., Klaassen, E. S., Gal, P. & Holst, A. G., 2024, (E-pub ahead of print) In: British Journal of Clinical Pharmacology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    Pharmacological inhibition of SK-channels with AP14145 prevents atrial arrhythmogenic changes in a porcine model for obstructive respiratory events

    Linz, Benedikt Maximilian, Hesselkilde, E. M., Skarsfeldt, M. A., Hertel, Julie Norup, Sattler, Stefan M, Yan, Y., Tfelt-Hansen, Jacob, Diness, Jonas Goldin, Bentzen, Bo Hjorth, Dr Linz, Dominik Karl & Jespersen, Thomas, 2023, In: Journal of Cardiovascular Electrophysiology. 34, 1, p. 126-134 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2021
  6. Published

    Effective termination of atrial fibrillation by SK channel inhibition is associated with a sudden organization of fibrillatory conduction

    Gatta, G., Sobota, V., Citerni, C., Diness, Jonas Goldin, Sørensen, U. S., Jespersen, Thomas, Bentzen, Bo Hjorth, Zeemering, S., Kuiper, M., Verheule, S., Schotten, U. & Van Hunnik, A., 2021, In: Europace. 23, 11, p. 1847-1859 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Small conductance calcium activated K+ channel inhibitor decreases stretch induced vulnerability to atrial fibrillation

    Yan, Y., Skarsfeldt, M. A., Diness, Jonas Goldin & Bentzen, Bo Hjorth, 2021, In: IJC Heart and Vasculature. 37, 8 p., 100898.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2019
  9. Published

    The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

    Kirchhoff, J. E., Skarsfeldt, M., Muthukumarasamy, K. M., Simó-Vicens, R., Bomholtz, Sofia Hammami, Abildgaard, L., Jespersen, Thomas, Sørensen, U. S., Grunnet, Morten, Bentzen, Bo Hjorth & Diness, Jonas Goldin, 2019, In: Frontiers in Pharmacology. 10, 13 p., 668.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2017
  11. Published

    A New Negative Allosteric Modulator AP14145 for the Study of Small Conductance Calcium-Activated Potassium Channels

    Simo Vicens, R., Kirchhoff, J. E., Dolce , B., Abildgaard, L., Speerschneider, T., Sørensen, U. S., Grunnet, Morten, Diness, Jonas Goldin & Bentzen, Bo Hjorth, 5 Dec 2017, In: British Journal of Pharmacology. 174, 23, p. 4396-4408 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

    Diness, Jonas Goldin, Skibsbye, L., Simó-Vicens, R., Louro Larupa dos Santos, J., Lundegaard, Pia Rengtved, Citerni, C., Sauter, D. R. P., Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, U. S., Jespersen, Thomas, Grunnet, Morten & Bentzen, Bo Hjorth, 10 Oct 2017, In: Circulation: Arrhythmia and Electrophysiology. 10, 19 p., e005125.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Effect of antiarrhythmic drugs on small conductance calcium –activated potassium channels

    Simo Vicens, R., Sauter, D. R. P., Grunnet, Morten, Diness, Jonas Goldin & Bentzen, Bo Hjorth, 15 May 2017, In: European Journal of Pharmacology. 803, p. 118-123 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Novel negative allosteric modulator inhibits small conductance calcium-activated potassium channels and selectively prolongs atrial refractoriness in conscious pigs

    Simó-Vicens, R., Citerni, C., Edvardsson, N. G., Sørensen, U. S., Grunnet, Morten, Diness, Jonas Goldin & Bentzen, Bo Hjorth, 11 May 2017, In: Heart Rhythm. 14, 5 suppl., p. S149-S150 P-PO02-15.

    Research output: Contribution to journal › Conference abstract in journal › Research

  15. 2016
  16. Published

    Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation

    Kirchhoff, J. E., Diness, Jonas Goldin, Abildgaard, L., Sheykhzade, Majid, Grunnet, Morten & Jespersen, Thomas, 8 Oct 2016, In: Pfluegers Archiv. 468, 11, p. 1853–1863 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2015
  18. Published

    Role of calcium activated potassium channels in atrial fibrillation pathophysiology and therapy

    Diness, Jonas Goldin, Bentzen, Bo Hjorth, S. Sørensen, U. & Grunnet, Morten, Nov 2015, In: Journal of Cardiovascular Pharmacology. 66, 5, p. 441-448 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 2014
  20. Published

    Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria

    Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, 1 Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-67 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarisation in human atria.

    Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-167 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2013
  23. Published

    Benzimidazolyl-acetamide derivatives useful as potassium channel modulators

    SØRENSEN, U. S., Grunnet, Morten, Bentzen, Bo Hjorth, Christophersen, P., Diness, Jonas Goldin, SKIBSBYE, L. & Strøbæk, D., 7 Jan 2013

    Research output: Other contribution › Research

  24. 2012
  25. Published

    Attenuated ventricular β-adrenergic response and reduced repolarization reserve in a rabbit model of chronic heart failure

    Nissen, J. D., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Diness, Jonas Goldin, Diness, T. G., Jespersen, Thomas & Grunnet, Morten, 2012, In: Journal of Cardiovascular Pharmacology. 59, 2, p. 142-150 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2011
  27. Published

    Cardiac ion channels and mechanisms for protection against atrial fibrillation.

    Grunnet, Morten, Bentzen, Bo Hjorth, Sørensen, U. S. & Diness, Jonas Goldin, 2011, In: Reviews of Physiology, Biochemistry and Pharmacology. 162, p. 1-58 59 p.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Effects on atrial fibrillation in aged hypertensive rats by Ca(2+)-activated K(+) channel inhibition

    Diness, Jonas Goldin, Skibsbye, L., Jespersen, Thomas, Bartels, Emil Daniel, Sørensen, U. S., Hansen, R. S. & Grunnet, Morten, 2011, In: Hypertension. 57, 6, p. 1129-35 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The duration of pacing-induced atrial fibrillation is reduced in vivo by inhibition of small conductance Ca2+-activated K+ channels.

    Skibsbye, L., Diness, Jonas Goldin, Sørensen, U. S., Hansen, R. S. & Grunnet, Morten, 2011, In: Journal of Cardiovascular Pharmacology. 57, 6, p. 672-681

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2010
  31. Published

    Inhibition of small-conductance Ca2+-activated K+ channels terminates and protects against atrial fibrillation

    Diness, Jonas Goldin, Sørensen, U. S., Nissen, J. D., Al-Shahib, B., Jespersen, T., Grunnet, Morten, Hansen, R. S. & Jespersen, Thomas, Aug 2010, In: Circulation. Arrhythmia and electrophysiology. 3, 4, p. 380-90 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2009
  33. Published

    Negative Modulation of SK Channels Terminates and Protects Against Atrial Fibrillation in Rat and Guinea Pig Ex Vivo and in vivo Models

    Diness, Jonas Goldin, Schultz Hansen, R., Sørensen, U. S. & Grunnet, Morten, 2009, In: Circulation. Supplement. 2009;120 (18): S712-S712 Suppl. 2.

    Research output: Contribution to journal › Conference article › Research › peer-review

  34. Published

    Pharmacologically induced long QT type 2 can be rescued by activation of IKs with benzodiazepine R-L3 in isolated guinea pig cardiomyocytes

    Nissen, J. D., Diness, Jonas Goldin, Diness, T. G., Hansen, R. S., Grunnet, Morten & Jespersen, Thomas, 2009, In: Journal of Cardiovascular Pharmacology. 54, 2, p. 169-77 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. 2008
  36. Published

    Antiarrhythmic effect of IKr activation in a cellular model of LQT3

    Diness, Jonas Goldin, Hansen, R. S., Nissen, J. D., Jespersen, Thomas & Grunnet, Morten, 2008, In: Heart Rhythm. 6, 1, p. 100-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 35356894