Alicia Lundby
Affiliate Associate Professor
Mann Group
Blegdamsvej 3B, 2200 København N
2200 København N
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52 Genetic Loci Influencing Myocardial Mass
van der Harst, P., van Setten, J., Verweij, N., Vogler, G., Franke, L., Maurano, M. T., Wang, X., Mateo Leach, I., Eijgelsheim, M., Sotoodehnia, N., Hayward, C., Sorice, R., Meirelles, O., Lyytikäinen, L., Polašek, O., Tanaka, T., Arking, D. E., Ulivi, S., Trompet, S., Müller-Nurasyid, M., Smith, A. V., Dörr, M., Kerr, K. F., Magnani, J. W., Del Greco M, F., Zhang, W., Nolte, I. M., Silva, C. T., Padmanabhan, S., Tragante, V., Esko, T., Abecasis, G. R., Adriaens, M. E., Andersen, K., Barnett, P., Bis, J. C., Bodmer, R., Buckley, B. M., Campbell, H., Cannon, M. V., Chakravarti, A., Chen, L. Y., Delitala, A., Devereux, R. B., Doevendans, P. A., Dominiczak, A. F., Ferrucci, L., Ford, I., Gieger, C., Harris, T. B., Haugen, E., Heinig, M., Hernandez, D. G., Hillege, H. L., Hirschhorn, J. N., Hofman, A., Hubner, N., Hwang, S., Iorio, A., Kähönen, M., Kellis, M., Kolcic, I., Kooner, I. K., Kooner, J. S., Kors, J. A., Lakatta, E. G., Lage, K., Launer, L. J., Levy, D., Lundby, Alicia, Macfarlane, P. W., May, D., Meitinger, T., Metspalu, A., Nappo, S., Naitza, S., Neph, S., Nord, A. S., Nutile, T., Okin, P. M., Olsen, Jesper Velgaard, Oostra, B. A., Penninger, J. M., Pennacchio, L. A., Pers, Tune H, Perz, S., Peters, A., Pinto, Y. M., Pfeufer, A., Pilia, M. G., Pramstaller, P. P., Prins, B. P., Raitakari, O. T., Raychaudhuri, S., Rice, K. M., Rossin, E. J., Rotter, J. I., Schafer, S., Schlessinger, D., Schmidt, C. O., Sehmi, J., Silljé, H. H. W., Sinagra, G., Sinner, M. F., Slowikowski, K., Soliman, E. Z., Spector, T. D., Spiering, W., Stamatoyannopoulos, J. A., Stolk, R. P., Strauch, K., Tan, S., Tarasov, K. V., Trinh, B., Uitterlinden, A. G., van den Boogaard, M., van Duijn, C. M., van Gilst, W. H., Viikari, J. S., Visscher, P. M., Vitart, V., Völker, U., Waldenberger, M., Weichenberger, C. X., Westra, H., Wijmenga, C., Wolffenbuttel, B. H., Yang, J., Bezzina, C. R., Munroe, P. B., Snieder, H., Wright, A. F., Rudan, I., Boyer, L. A., Asselbergs, F. W., van Veldhuisen, D. J., Stricker, B. H., Psaty, B. M., Ciullo, M., Sanna, S., Lehtimäki, T., Wilson, J. F., Bandinelli, S., Alonso, A., Gasparini, P., Jukema, J. W., Kääb, S., Gudnason, V., Felix, S. B., Heckbert, S. R., de Boer, R. A., Newton-Cheh, C., Hicks, A. A., Chambers, J. C., Jamshidi, Y., Visel, A., Christoffels, V. M., Isaacs, A., Samani, N. J. & de Bakker, P. I. W., 27 Sep 2016, In: Journal of the American College of Cardiology. 68, 13, p. 1435-48 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reevaluation of genetic variants previously associated with arrhythmogenic right ventricular cardiomyopathy integrating population-based cohorts and proteomics data
Ye, J. Z., Delmar, M., Lundby, Alicia & Olesen, Morten Steen Salling, 2019, In: Clinical Genetics. 96, 6, p. 506-514Research output: Contribution to journal › Journal article › Research › peer-review
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Oncotherapeutic Protein Kinase Inhibitors Associated With Pro-Arrhythmic Liability
Ye, J. Z., Hansen, F. B., Mills, Robert William & Lundby, Alicia, 2021, In: JACC: CardioOncology. 3, 1, p. 88-97Research output: Contribution to journal › Journal article › Research › peer-review
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Ibrutinib-Mediated Atrial Fibrillation Attributable to Inhibition of C-Terminal Src Kinase
Xiao, L., Salem, J., Clauss, S., Hanley, A., Bapat, A., Hulsmans, M., Iwamoto, Y., Wojtkiewicz, G., Cetinbas, M., Schloss, M. J., Tedeschi, J., Lebrun-Vignes, B., Lundby, Alicia, Sadreyev, R., Moslehi, J., Nahrendorf, M., Ellinor, P. T. & Milan, D. J., 2020, In: Circulation. 142, 25, p. 2443-2455 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The PI3-kinase isoform p110δ is essential for cell transformation induced by the D816V mutant of c-Kit in a lipid-kinase-independent manner
Sun, J., Mohlin, S., Lundby, Alicia, Kazi, J. U., Hellman, U., Påhlman, S., Olsen, Jesper Velgaard & Rönnstrand, L., 11 Nov 2013, In: Oncogene.Research output: Contribution to journal › Journal article › Research › peer-review
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PKD Phosphorylation as Novel Pathway of KV11.1 Regulation
Steffensen, Annette Buur, Bomholtz, Sofia Hammami, Andersen, M. N., Olsen, Jesper Velgaard, Mutsaers, N., Lundegaard, Pia Rengtved, Lundby, Alicia & Schmitt, Nicole, 2018, In: Cellular Physiology and Biochemistry. 47, 4, p. 1742-1750 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Beta-blocker/ACE inhibitor therapy differentially impacts the steady state signaling landscape of failing and non-failing hearts
Sorrentino, Andrea, Bagwan, Navratan, Linscheid, N., Poulsen, P., Kahnert, Konstantin, Thomsen, Morten Bækgaard, Delmar, M. & Lundby, Alicia, 2021, In: European Heart Journal. 42, Suppl. 1, p. 3294-3294 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Molecular template for a voltage sensor in a novel K+ channel I. Identification and functional characterization of KvLm, a voltage-gated K+ channel form Listeria monocytogenes
Santos, J., Lundby, Alicia, Zazueta, C. & Montal, M., 2006, In: Journal of General Physiology. 128 (3), p. 283-292Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse
Roselli, C., Yu, M., Nauffal, V., Georges, A., Yang, Q., Love, K., Weng, L., Delling, F. N., Maurya, S. R., Schrölkamp, Maren, Tfelt-Hansen, Jacob, Hagège, A., Jeunemaitre, X., Debette, S., Amouyel, P., Guan, W., Muehlschlegel, J. D., Body, S. C., Shah, S., Samad, Z., Kyryachenko, S., Haynes, C., Rienstra, M., Le Tourneau, T., Probst, V., Roussel, R., Wijdh-Den Hamer, I. J., Siland, J. E., Knowlton, K. U., Jacques Schott, J., Levine, R. A., Benjamin, E. J., Vasan, R. S., Horne, B. D., Muhlestein, J. B., Benfari, G., Enriquez-Sarano, M., Natale, A., Mohanty, S., Trivedi, C., Shoemaker, M. B., Yoneda, Z. T., Wells, Q. S., Baker, M. T., Farber-Eger, E., Michelena, H. I., Lundby, Alicia, Norris, R. A., Slaugenhaupt, S. A., Dina, C., Lubitz, S. A., Bouatia-Naji, N., Ellinor, P. T. & Milan, D. J., 2022, In: European Heart Journal. 43, 17, p. 1668–1680Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative proteomics characterization of acutely isolated primary adult rat cardiomyocytes and fibroblasts
Poulsen, P. C., Schrölkamp, Maren, Bagwan, Navratan, Leurs, U., Humphries, E. S. A., Bomholzt, S. H., Nielsen, Morten Schak, Bentzen, Bo Hjorth, Olsen, Jesper Velgaard & Lundby, Alicia, 2020, In: Journal of Molecular and Cellular Cardiology. 143, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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KIT(D816V) Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma
Phung, B., Kazi, J. U., Lundby, Alicia, Bergsteinsdottir, K., Sun, J., Goding, C. R., Jönsson, G., Olsen, Jesper Velgaard, Steingrímsson, E. & Rönnstrand, L., 2017, In: Molecular cancer research : MCR. 15, 9, p. 1265-1274 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution
Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Koenig, Claire, Østergaard, Ole, Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, Ewa, Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 17 p., 7113.Research output: Contribution to journal › Journal article › Research › peer-review
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Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics
Lundby, Alicia, Rossin, E. J., Steffensen, Annette Buur, Acha, M. R., Newton-Cheh, C., Pfeufer, A., Lynch, S. N., Olesen, Søren-Peter, Brunak, Søren, Ellinor, P. T., Jukema, J. W., Trompet, S., Ford, I., Macfarlane, P. W., Krijthe, B. P., Hofman, A., Uitterlinden, A. G., Stricker, B. H., Nathoe, H. M., Spiering, W., Daly, M. J., Asselbergs, F. W., van der Harst, P., Milan, D. J., de Bakker, P. I. W., Hansen, K. L., Olsen, Jesper Velgaard & The QT Interval International GWAS Consortium (QT-IGC), T. Q. I. I. G. C. (., 22 Jun 2014, In: Nature Methods. 11, 8, p. 868-874 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Flere kvinder giver fair play
Lundby, Alicia, Gerken, M., Quist, Pia, Bille, M. & Dahl, Tais Wittchen, 29 May 2015, In: Weekendavisen.Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication
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KCNE3 is an inhibitory subunit of the Kv4.3 potassium channel.
Lundby, Alicia & Olesen, Søren-Peter, 2006, In: Biochemical and Biophysical Research Communications. 346, 3, p. 958-67 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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KCNE3 mutation V17M identified in a patient with lone atrial fibrillation.
Lundby, Alicia, Ravn, L. S., Svendsen, J. H., Hauns, S., Olesen, Søren-Peter & Schmitt, Nicole, 2008, In: Cellular Physiology and Biochemistry. 21, 1-3, p. 47-54 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval.
Lundby, Alicia, Ravn, L. S., Svendsen, Jesper Hastrup, Olesen, Søren-Peter & Schmitt, Nicole, 2007, In: Heart Rhythm. 4, 12, p. 1532-41 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, Sebastian Peter, Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues
Lundby, Alicia, Secher, A., Lage, K., Nordsborg, Nikolai Baastrup, Dmytriyev, A., Lundby, C. & Olsen, Jesper Velgaard, 6 Jun 2012, In: Nature Communications. 3, p. 1-10 10 p., Article 876.Research output: Contribution to journal › Journal article › Research › peer-review
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Engineering of a genetically encodable fluorescent voltage sensor exploiting fast Ci-VSP voltage-sensing movements
Lundby, Alicia, Mutoh, H., Dimitrov, D., Akemann, W. & Knöpfel, T., 2008, In: PLoS ONE. 3, 6, p. e2514Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular template for a voltage sensor in a novel K+ channel II. Conservation of a eukaryotic sensor fold in a prokaryotic K+ channel
Lundby, Alicia, Santos, J., Zazueta, C. & Montal, M., 2006, In: Journal of General Physiology. 128 (3), p. 293-300Research output: Contribution to journal › Journal article › Research › peer-review
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In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling
Lundby, Alicia, Andersen, M. N., Steffensen, Annette Buur, Horn, H., Kelstrup, C. D., Francavilla, C., Jensen, Lars Juhl, Schmitt, Nicole, Thomsen, Morten Bækgaard & Olsen, Jesper Velgaard, 4 Jun 2013, In: Science Signaling. 6, 278, p. rs11 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biophysical characterization of the fluorescent protein voltage probe VSFP2.3 based on the voltage-sensing domain of Ci-VSP
Lundby, Alicia, Akemann, W. & Knöpfel, T., 6 Aug 2010, In: European Biophysics Journal. 39, 12, p. 1625-1635 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GeLCMS for in-depth protein characterization and advanced analysis of proteomes
Lundby, Alicia & Olsen, Jesper Velgaard, 1 Jan 2011, Gel-Free Proteomics Methods and Protocols. Vol. 753. p. 143-55 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Structural basis for KV7.1/KCNEx interactions in the IKs channel complex
Lundby, Alicia, Tseng, G. & Schmitt, Nicole, 2010, In: Heart Rhythm. 7, 5, p. 708-713Research output: Contribution to journal › Journal article › Research › peer-review
ID: 10426
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52 Genetic Loci Influencing Myocardial Mass
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
316
downloads
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Research output: Contribution to journal › Journal article › Research › peer-review
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315
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Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Research output: Contribution to journal › Journal article › Research › peer-review
Published