Alicia Lundby

Alicia Lundby

Affiliated Associate Professor, Professor with special responsibilities, Professor MSO

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    ORCID: 0000-0002-1612-6041

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    1. Published

      52 Genetic Loci Influencing Myocardial Mass

      van der Harst, P., van Setten, J., Verweij, N., Vogler, G., Franke, L., Maurano, M. T., Wang, X., Mateo Leach, I., Eijgelsheim, M., Sotoodehnia, N., Hayward, C., Sorice, R., Meirelles, O., Lyytikäinen, L-P., Polašek, O., Tanaka, T., Arking, D. E., Ulivi, S., Trompet, S., Müller-Nurasyid, M. & 140 others, Smith, A. V., Dörr, M., Kerr, K. F., Magnani, J. W., Del Greco M, F., Zhang, W., Nolte, I. M., Silva, C. T., Padmanabhan, S., Tragante, V., Esko, T., Abecasis, G. R., Adriaens, M. E., Andersen, K., Barnett, P., Bis, J. C., Bodmer, R., Buckley, B. M., Campbell, H., Cannon, M. V., Chakravarti, A., Chen, L. Y., Delitala, A., Devereux, R. B., Doevendans, P. A., Dominiczak, A. F., Ferrucci, L., Ford, I., Gieger, C., Harris, T. B., Haugen, E., Heinig, M., Hernandez, D. G., Hillege, H. L., Hirschhorn, J. N., Hofman, A., Hubner, N., Hwang, S., Iorio, A., Kähönen, M., Kellis, M., Kolcic, I., Kooner, I. K., Kooner, J. S., Kors, J. A., Lakatta, E. G., Lage, K., Launer, L. J., Levy, D., Lundby, Alicia, Macfarlane, P. W., May, D., Meitinger, T., Metspalu, A., Nappo, S., Naitza, S., Neph, S., Nord, A. S., Nutile, T., Okin, P. M., Olsen, Jesper Velgaard, Oostra, B. A., Penninger, J. M., Pennacchio, L. A., Pers, Tune H, Perz, S., Peters, A., Pinto, Y. M., Pfeufer, A., Pilia, M. G., Pramstaller, P. P., Prins, B. P., Raitakari, O. T., Raychaudhuri, S., Rice, K. M., Rossin, E. J., Rotter, J. I., Schafer, S., Schlessinger, D., Schmidt, C. O., Sehmi, J., Silljé, H. H. W., Sinagra, G., Sinner, M. F., Slowikowski, K., Soliman, E. Z., Spector, T. D., Spiering, W., Stamatoyannopoulos, J. A., Stolk, R. P., Strauch, K., Tan, S., Tarasov, K. V., Trinh, B., Uitterlinden, A. G., van den Boogaard, M., van Duijn, C. M., van Gilst, W. H., Viikari, J. S., Visscher, P. M., Vitart, V., Völker, U., Waldenberger, M., Weichenberger, C. X., Westra, H., Wijmenga, C., Wolffenbuttel, B. H., Yang, J., Bezzina, C. R., Munroe, P. B., Snieder, H., Wright, A. F., Rudan, I., Boyer, L. A., Asselbergs, F. W., van Veldhuisen, D. J., Stricker, B. H., Psaty, B. M., Ciullo, M., Sanna, S., Lehtimäki, T., Wilson, J. F., Bandinelli, S., Alonso, A., Gasparini, P., Jukema, J. W., Kääb, S., Gudnason, V., Felix, S. B., Heckbert, S. R., de Boer, R. A., Newton-Cheh, C., Hicks, A. A., Chambers, J. C., Jamshidi, Y., Visel, A., Christoffels, V. M., Isaacs, A., Samani, N. J. & de Bakker, P. I. W., 27 Sep 2016, In: Journal of the American College of Cardiology. 68, 13, p. 1435-48 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Reevaluation of genetic variants previously associated with arrhythmogenic right ventricular cardiomyopathy integrating population-based cohorts and proteomics data

      Ye, J. Z., Delmar, M., Lundby, Alicia & Olesen, Morten Steen Salling, 2019, In: Clinical Genetics. 96, 6, p. 506-514

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Oncotherapeutic Protein Kinase Inhibitors Associated With Pro-Arrhythmic Liability

      Ye, J. Z., Hansen, F. B., Mills, Robert William & Lundby, Alicia, 2021, In: JACC: CardioOncology. 3, 1, p. 88-97

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Ibrutinib-Mediated Atrial Fibrillation Attributable to Inhibition of C-Terminal Src Kinase

      Xiao, L., Salem, J., Clauss, S., Hanley, A., Bapat, A., Hulsmans, M., Iwamoto, Y., Wojtkiewicz, G., Cetinbas, M., Schloss, M. J., Tedeschi, J., Lebrun-Vignes, B., Lundby, Alicia, Sadreyev, R., Moslehi, J., Nahrendorf, M., Ellinor, P. T. & Milan, D. J., 2020, In: Circulation. 142, 25, p. 2443-2455 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2-Deficient Hearts

      Van Opbergen, C. J. M., Bagwan, N., Maurya, S. R., Kim, J. C., Smith, A. N., Blackwell, D. J., Johnston, J. N., Knollmann, B. C., Cerrone, M., Lundby, Alicia & Delmar, M., 2022, In: Circulation. 145, 19, p. 1480-1496

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      The PI3-kinase isoform p110δ is essential for cell transformation induced by the D816V mutant of c-Kit in a lipid-kinase-independent manner

      Sun, J., Mohlin, S., Lundby, Alicia, Kazi, J. U., Hellman, U., Påhlman, S., Olsen, Jesper Velgaard & Rönnstrand, L., 11 Nov 2013, In: Oncogene.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      PKD Phosphorylation as Novel Pathway of KV11.1 Regulation

      Steffensen, Annette Buur, Bomholtz, Sofia Hammami, Andersen, M. N., Olsen, Jesper Velgaard, Mutsaers, N., Lundegaard, Pia Rengtved, Lundby, Alicia & Schmitt, Nicole, 2018, In: Cellular Physiology and Biochemistry. 47, 4, p. 1742-1750 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Beta-blocker/ACE inhibitor therapy differentially impacts the steady state signaling landscape of failing and non-failing hearts

      Sorrentino, Andrea, Bagwan, N., Linscheid, N., Poulsen, P. C., Kahnert, Konstantin, Thomsen, Morten Bækgaard, Delmar, M. & Lundby, Alicia, Dec 2022, In: Scientific Reports. 12, 1, 13 p., 4760.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Beta-blocker/ACE inhibitor therapy differentially impacts the steady state signaling landscape of failing and non-failing hearts

      Sorrentino, Andrea, Bagwan, N., Linscheid, N., Poulsen, P., Kahnert, Konstantin, Thomsen, Morten Bækgaard, Delmar, M. & Lundby, Alicia, 2021, In: European Heart Journal. 42, Suppl. 1, p. 3294-3294 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    10. Published

      Molecular template for a voltage sensor in a novel K+ channel I. Identification and functional characterization of KvLm, a voltage-gated K+ channel form Listeria monocytogenes

      Santos, J., Lundby, Alicia, Zazueta, C. & Montal, M., 2006, In: Journal of General Physiology. 128 (3), p. 283-292

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse

      Roselli, C., Yu, M., Nauffal, V., Georges, A., Yang, Q., Love, K., Weng, L-C., Delling, F. N., Maurya, S. R., Schrölkamp, M., Tfelt-Hansen, J., Hagège, A., Jeunemaitre, X., Debette, S., Amouyel, P., Guan, W., Muehlschlegel, J. D., Body, S. C., Shah, S., Samad, Z. & 34 others, Kyryachenko, S., Haynes, C., Rienstra, M., Le Tourneau, T., Probst, V., Roussel, R., Wijdh-Den Hamer, I. J., Siland, J. E., Knowlton, K. U., Jacques Schott, J., Levine, R. A., Benjamin, E. J., Vasan, R. S., Horne, B. D., Muhlestein, J. B., Benfari, G., Enriquez-Sarano, M., Natale, A., Mohanty, S., Trivedi, C., Shoemaker, M. B., Yoneda, Z. T., Wells, Q. S., Baker, M. T., Farber-Eger, E., Michelena, H. I., Lundby, Alicia, Norris, R. A., Slaugenhaupt, S. A., Dina, C., Lubitz, S. A., Bouatia-Naji, N., Ellinor, P. T. & Milan, D. J., 2022, In: European Heart Journal. 43, 17, p. 1668–1680

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Quantitative proteomics characterization of acutely isolated primary adult rat cardiomyocytes and fibroblasts

      Poulsen, P. C., Schrölkamp, Maren, Bagwan, N., Leurs, U., Humphries, E. S. A., Bomholzt, S. H., Nielsen, Morten Schak, Bentzen, Bo Hjorth, Olsen, Jesper Velgaard & Lundby, Alicia, 2020, In: Journal of Molecular and Cellular Cardiology. 143, p. 63-70 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Functional modulation of a pH-sensitive ion channel by a transporter family

      Poulsen, Mette Homann, Xue, F., Maurya, S. R., Kickinger, Stefanie, Usher, Samuel George, Wellendorph, Petrine, Lundby, Alicia & Pless, Stephan, 2023, In: Biophysical Journal. 122, 3 Suppl. 1, p. 249a

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    14. Published

      KIT(D816V) Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma

      Phung, B., Kazi, J. U., Lundby, Alicia, Bergsteinsdottir, K., Sun, J., Goding, C. R., Jönsson, G., Olsen, Jesper Velgaard, Steingrímsson, E. & Rönnstrand, L., 2017, In: Molecular cancer research : MCR. 15, 9, p. 1265-1274 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Loss of Nuclear Envelope Integrity and Increased Oxidant Production Cause DNA Damage in Adult Hearts Deficient in PKP2: A Molecular Substrate of ARVC

      Perez-Hernandez, M., van Opbergen, C. J. M., Bagwan, N., Vissing, C. R., Marron-Linares, G. M., Zhang, M., Vega, E. T., Sorrentino, A., Drici, L., Sulek, K., Zhai, R., Hansen, F. B., Christensen, A. H., Boesgaard, S., Gustafsson, F., Rossing, K., Small, E. M., Davies, M. J., Rothenberg, E., Sato, P. Y. & 6 others, Cerrone, M., Jensen, Thomas Hartvig Lindkær, Qvortrup, Klaus, Bundgård, Henning, Delmar, M. & Lundby, Alicia, 2022, In: Circulation. 146, 11, p. 851-867

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Outlining cardiac ion channel protein interactors and their signature in the human electrocardiogram

      Maurya, S., Mills, Robert William, Kahnert, Konstantin, Chiang, D. Y., Bertoli, G., Lundegaard, Pia Rengtved, Duran, M. P. H., Zhang, M., Rothenberg, E., George, A. L., MacRae, C. A., Delmar, M. & Lundby, Alicia, 2023, In: Nature Cardiovascular Research. 2, 7, p. 673-692 38 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution

      Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Koenig, Claire, Østergaard, Ole, Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 17 p., 7113.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Spatial-proteomics reveal in-vivo phospho-signaling dynamics at subcellular resolution

      Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2 Feb 2021, bioRxiv, p. 1-34, 34 p.

      Research output: Working paper › Preprint › Research

    19. Published

      Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

      Lundby, A., Rossin, E. J., Steffensen, A. B., Acha, M. R., Newton-Cheh, C., Pfeufer, A., Lynch, S. N., Olesen, S-P., Brunak, S., Ellinor, P. T., Jukema, J. W., Trompet, S., Ford, I., Macfarlane, P. W., Krijthe, B. P., Hofman, A., Uitterlinden, A. G., Stricker, B. H., Nathoe, H. M., Spiering, W. & 8 others, Daly, M. J., Asselbergs, F. W., van der Harst, P., Milan, D. J., de Bakker, P. I. W., Hansen, K. L., Olsen, Jesper Velgaard & The QT Interval International GWAS Consortium (QT-IGC), T. Q. I. I. G. C. (., 22 Jun 2014, In: Nature Methods. 11, 8, p. 868-874 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Engineering of a genetically encodable fluorescent voltage sensor exploiting fast Ci-VSP voltage-sensing movements

      Lundby, Alicia, Mutoh, H., Dimitrov, D., Akemann, W. & Knöpfel, T., 2008, In: PLoS ONE. 3, 6, p. e2514

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Molecular template for a voltage sensor in a novel K+ channel II. Conservation of a eukaryotic sensor fold in a prokaryotic K+ channel

      Lundby, Alicia, Santos, J., Zazueta, C. & Montal, M., 2006, In: Journal of General Physiology. 128 (3), p. 293-300

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling

      Lundby, Alicia, Andersen, M. N., Steffensen, Annette Buur, Horn, H., Kelstrup, C. D., Francavilla, C., Jensen, Lars Juhl, Schmitt, Nicole, Thomsen, Morten Bækgaard & Olsen, Jesper Velgaard, 4 Jun 2013, In: Science Signaling. 6, 278, p. rs11 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Biophysical characterization of the fluorescent protein voltage probe VSFP2.3 based on the voltage-sensing domain of Ci-VSP

      Lundby, Alicia, Akemann, W. & Knöpfel, T., 6 Aug 2010, In: European Biophysics Journal. 39, 12, p. 1625-1635 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      GeLCMS for in-depth protein characterization and advanced analysis of proteomes

      Lundby, Alicia & Olsen, Jesper Velgaard, 1 Jan 2011, Gel-Free Proteomics Methods and Protocols. Vol. 753. p. 143-55 13 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    25. Published

      Structural basis for KV7.1/KCNEx interactions in the IKs channel complex

      Lundby, Alicia, Tseng, G. & Schmitt, Nicole, 2010, In: Heart Rhythm. 7, 5, p. 708-713

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 10426