Small intestine vs. colon ecology and physiology: Why it matters in probiotic administration

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Small intestine vs. colon ecology and physiology : Why it matters in probiotic administration. / Jensen, Benjamin Anderschou Holbech; Heyndrickx, Marc; Jonkers, Daisy; Mackie, Alan; Millet, Sam; Naghibi, Malwina; Pærregaard, Simone Isling; Pot, Bruno; Saulnier, Delphine; Sina, Christian; Sterkman, Luc Gerardus Willibrordus; Van den Abbeele, Pieter; Venlet, Naomi Vita; Zoetendal, Erwin G.; Ouwehand, Arthur Constantijn.

I: Cell Reports Medicine, Bind 4, Nr. 9, 101190, 2023.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Jensen, BAH, Heyndrickx, M, Jonkers, D, Mackie, A, Millet, S, Naghibi, M, Pærregaard, SI, Pot, B, Saulnier, D, Sina, C, Sterkman, LGW, Van den Abbeele, P, Venlet, NV, Zoetendal, EG & Ouwehand, AC 2023, 'Small intestine vs. colon ecology and physiology: Why it matters in probiotic administration', Cell Reports Medicine, bind 4, nr. 9, 101190. https://doi.org/10.1016/j.xcrm.2023.101190

APA

Jensen, B. A. H., Heyndrickx, M., Jonkers, D., Mackie, A., Millet, S., Naghibi, M., Pærregaard, S. I., Pot, B., Saulnier, D., Sina, C., Sterkman, L. G. W., Van den Abbeele, P., Venlet, N. V., Zoetendal, E. G., & Ouwehand, A. C. (2023). Small intestine vs. colon ecology and physiology: Why it matters in probiotic administration. Cell Reports Medicine, 4(9), [101190]. https://doi.org/10.1016/j.xcrm.2023.101190

Vancouver

Jensen BAH, Heyndrickx M, Jonkers D, Mackie A, Millet S, Naghibi M o.a. Small intestine vs. colon ecology and physiology: Why it matters in probiotic administration. Cell Reports Medicine. 2023;4(9). 101190. https://doi.org/10.1016/j.xcrm.2023.101190

Author

Jensen, Benjamin Anderschou Holbech ; Heyndrickx, Marc ; Jonkers, Daisy ; Mackie, Alan ; Millet, Sam ; Naghibi, Malwina ; Pærregaard, Simone Isling ; Pot, Bruno ; Saulnier, Delphine ; Sina, Christian ; Sterkman, Luc Gerardus Willibrordus ; Van den Abbeele, Pieter ; Venlet, Naomi Vita ; Zoetendal, Erwin G. ; Ouwehand, Arthur Constantijn. / Small intestine vs. colon ecology and physiology : Why it matters in probiotic administration. I: Cell Reports Medicine. 2023 ; Bind 4, Nr. 9.

Bibtex

@article{b6cfc1a32ed74da69314b7134d3f9501,
title = "Small intestine vs. colon ecology and physiology: Why it matters in probiotic administration",
abstract = "Research on gut microbiota has generally focused on fecal samples, representing luminal content of the large intestine. However, nutrient uptake is restricted to the small intestine. Abundant immune cell populations at this anatomical site combined with diminished mucus secretion and looser junctions (partly to allow for more efficient fluid and nutrient absorption) also results in intimate host-microbe interactions despite more rapid transit. It is thus crucial to dissect key differences in both ecology and physiology between small and large intestine to better leverage the immense potential of human gut microbiota imprinting, including probiotic engraftment at biological sensible niches. Here, we provide a detailed review unfolding how the physiological and anatomical differences between the small and large intestine affect gut microbiota composition, function, and plasticity. This information is key to understanding how gut microbiota manipulation, including probiotic administration, may strain-dependently transform host-microbe interactions at defined locations.",
author = "Jensen, {Benjamin Anderschou Holbech} and Marc Heyndrickx and Daisy Jonkers and Alan Mackie and Sam Millet and Malwina Naghibi and P{\ae}rregaard, {Simone Isling} and Bruno Pot and Delphine Saulnier and Christian Sina and Sterkman, {Luc Gerardus Willibrordus} and {Van den Abbeele}, Pieter and Venlet, {Naomi Vita} and Zoetendal, {Erwin G.} and Ouwehand, {Arthur Constantijn}",
note = "Publisher Copyright: {\textcopyright} 2023 The Authors",
year = "2023",
doi = "10.1016/j.xcrm.2023.101190",
language = "English",
volume = "4",
journal = "Cell Reports Medicine",
issn = "2666-3791",
publisher = "Cell Press",
number = "9",

}

RIS

TY - JOUR

T1 - Small intestine vs. colon ecology and physiology

T2 - Why it matters in probiotic administration

AU - Jensen, Benjamin Anderschou Holbech

AU - Heyndrickx, Marc

AU - Jonkers, Daisy

AU - Mackie, Alan

AU - Millet, Sam

AU - Naghibi, Malwina

AU - Pærregaard, Simone Isling

AU - Pot, Bruno

AU - Saulnier, Delphine

AU - Sina, Christian

AU - Sterkman, Luc Gerardus Willibrordus

AU - Van den Abbeele, Pieter

AU - Venlet, Naomi Vita

AU - Zoetendal, Erwin G.

AU - Ouwehand, Arthur Constantijn

N1 - Publisher Copyright: © 2023 The Authors

PY - 2023

Y1 - 2023

N2 - Research on gut microbiota has generally focused on fecal samples, representing luminal content of the large intestine. However, nutrient uptake is restricted to the small intestine. Abundant immune cell populations at this anatomical site combined with diminished mucus secretion and looser junctions (partly to allow for more efficient fluid and nutrient absorption) also results in intimate host-microbe interactions despite more rapid transit. It is thus crucial to dissect key differences in both ecology and physiology between small and large intestine to better leverage the immense potential of human gut microbiota imprinting, including probiotic engraftment at biological sensible niches. Here, we provide a detailed review unfolding how the physiological and anatomical differences between the small and large intestine affect gut microbiota composition, function, and plasticity. This information is key to understanding how gut microbiota manipulation, including probiotic administration, may strain-dependently transform host-microbe interactions at defined locations.

AB - Research on gut microbiota has generally focused on fecal samples, representing luminal content of the large intestine. However, nutrient uptake is restricted to the small intestine. Abundant immune cell populations at this anatomical site combined with diminished mucus secretion and looser junctions (partly to allow for more efficient fluid and nutrient absorption) also results in intimate host-microbe interactions despite more rapid transit. It is thus crucial to dissect key differences in both ecology and physiology between small and large intestine to better leverage the immense potential of human gut microbiota imprinting, including probiotic engraftment at biological sensible niches. Here, we provide a detailed review unfolding how the physiological and anatomical differences between the small and large intestine affect gut microbiota composition, function, and plasticity. This information is key to understanding how gut microbiota manipulation, including probiotic administration, may strain-dependently transform host-microbe interactions at defined locations.

UR - http://www.scopus.com/inward/record.url?scp=85171151948&partnerID=8YFLogxK

U2 - 10.1016/j.xcrm.2023.101190

DO - 10.1016/j.xcrm.2023.101190

M3 - Review

C2 - 37683651

AN - SCOPUS:85171151948

VL - 4

JO - Cell Reports Medicine

JF - Cell Reports Medicine

SN - 2666-3791

IS - 9

M1 - 101190

ER -

ID: 369136130