Modulation of KCNQ4 channel activity by changes in cell volume.

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Standard

Modulation of KCNQ4 channel activity by changes in cell volume. / Hougaard, Charlotte; Klaerke, Dan A; Hoffmann, Else K; Olesen, Søren-Peter; Jorgensen, Nanna K.

I: BBA General Subjects, Bind 1660, Nr. 1-2, 2004, s. 1-6.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Hougaard, C, Klaerke, DA, Hoffmann, EK, Olesen, S-P & Jorgensen, NK 2004, 'Modulation of KCNQ4 channel activity by changes in cell volume.', BBA General Subjects, bind 1660, nr. 1-2, s. 1-6. https://doi.org/10.1016/j.bbamem.2003.11.015

APA

Hougaard, C., Klaerke, D. A., Hoffmann, E. K., Olesen, S-P., & Jorgensen, N. K. (2004). Modulation of KCNQ4 channel activity by changes in cell volume. BBA General Subjects, 1660(1-2), 1-6. https://doi.org/10.1016/j.bbamem.2003.11.015

Vancouver

Hougaard C, Klaerke DA, Hoffmann EK, Olesen S-P, Jorgensen NK. Modulation of KCNQ4 channel activity by changes in cell volume. BBA General Subjects. 2004;1660(1-2):1-6. https://doi.org/10.1016/j.bbamem.2003.11.015

Author

Hougaard, Charlotte ; Klaerke, Dan A ; Hoffmann, Else K ; Olesen, Søren-Peter ; Jorgensen, Nanna K. / Modulation of KCNQ4 channel activity by changes in cell volume. I: BBA General Subjects. 2004 ; Bind 1660, Nr. 1-2. s. 1-6.

Bibtex

@article{689f4b70a0f311dd86a6000ea68e967b,
title = "Modulation of KCNQ4 channel activity by changes in cell volume.",
abstract = "KCNQ4 channels expressed in HEK 293 cells are sensitive to cell volume changes, being activated by swelling and inhibited by shrinkage, respectively. The KCNQ4 channels contribute significantly to the regulatory volume decrease (RVD) process following cell swelling. Under isoosmotic conditions, the KCNQ4 channel activity is modulated by protein kinases A and C, G protein activation, and a reduction in the intracellular Ca2+ concentration, but these signalling pathways are not responsible for the increased channel activity during cell swelling.",
author = "Charlotte Hougaard and Klaerke, {Dan A} and Hoffmann, {Else K} and S{\o}ren-Peter Olesen and Jorgensen, {Nanna K}",
note = "Keywords: Calcium; Carbamates; Cell Line; Cell Size; Cyclic AMP-Dependent Protein Kinases; Humans; Indoles; KCNQ Potassium Channels; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Osmolar Concentration; Patch-Clamp Techniques; Phenylenediamines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase C; Pyridines; Signal Transduction",
year = "2004",
doi = "10.1016/j.bbamem.2003.11.015",
language = "English",
volume = "1660",
pages = "1--6",
journal = "B B A - General Subjects",
issn = "0304-4165",
publisher = "Elsevier",
number = "1-2",

}

RIS

TY - JOUR

T1 - Modulation of KCNQ4 channel activity by changes in cell volume.

AU - Hougaard, Charlotte

AU - Klaerke, Dan A

AU - Hoffmann, Else K

AU - Olesen, Søren-Peter

AU - Jorgensen, Nanna K

N1 - Keywords: Calcium; Carbamates; Cell Line; Cell Size; Cyclic AMP-Dependent Protein Kinases; Humans; Indoles; KCNQ Potassium Channels; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Osmolar Concentration; Patch-Clamp Techniques; Phenylenediamines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase C; Pyridines; Signal Transduction

PY - 2004

Y1 - 2004

N2 - KCNQ4 channels expressed in HEK 293 cells are sensitive to cell volume changes, being activated by swelling and inhibited by shrinkage, respectively. The KCNQ4 channels contribute significantly to the regulatory volume decrease (RVD) process following cell swelling. Under isoosmotic conditions, the KCNQ4 channel activity is modulated by protein kinases A and C, G protein activation, and a reduction in the intracellular Ca2+ concentration, but these signalling pathways are not responsible for the increased channel activity during cell swelling.

AB - KCNQ4 channels expressed in HEK 293 cells are sensitive to cell volume changes, being activated by swelling and inhibited by shrinkage, respectively. The KCNQ4 channels contribute significantly to the regulatory volume decrease (RVD) process following cell swelling. Under isoosmotic conditions, the KCNQ4 channel activity is modulated by protein kinases A and C, G protein activation, and a reduction in the intracellular Ca2+ concentration, but these signalling pathways are not responsible for the increased channel activity during cell swelling.

U2 - 10.1016/j.bbamem.2003.11.015

DO - 10.1016/j.bbamem.2003.11.015

M3 - Journal article

C2 - 14757214

VL - 1660

SP - 1

EP - 6

JO - B B A - General Subjects

JF - B B A - General Subjects

SN - 0304-4165

IS - 1-2

ER -

ID: 6768730