Immunohistochemical localization of epidermal growth factor in the second-trimester human fetus

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Immunohistochemical localization of epidermal growth factor in the second-trimester human fetus. / Poulsen, Steen Seier; Kryger-Baggesen, N; Nexø, Ebba.

I: Histochemistry and Cell Biology, Bind 105, Nr. 2, 02.1996, s. 111-7.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Poulsen, SS, Kryger-Baggesen, N & Nexø, E 1996, 'Immunohistochemical localization of epidermal growth factor in the second-trimester human fetus', Histochemistry and Cell Biology, bind 105, nr. 2, s. 111-7.

APA

Poulsen, S. S., Kryger-Baggesen, N., & Nexø, E. (1996). Immunohistochemical localization of epidermal growth factor in the second-trimester human fetus. Histochemistry and Cell Biology, 105(2), 111-7.

Vancouver

Poulsen SS, Kryger-Baggesen N, Nexø E. Immunohistochemical localization of epidermal growth factor in the second-trimester human fetus. Histochemistry and Cell Biology. 1996 feb.;105(2):111-7.

Author

Poulsen, Steen Seier ; Kryger-Baggesen, N ; Nexø, Ebba. / Immunohistochemical localization of epidermal growth factor in the second-trimester human fetus. I: Histochemistry and Cell Biology. 1996 ; Bind 105, Nr. 2. s. 111-7.

Bibtex

@article{cd29ca70d16c4f08b325c3e020c8ac59,
title = "Immunohistochemical localization of epidermal growth factor in the second-trimester human fetus",
abstract = "Epidermal growth factor (EGF) is considered to be important in mammalian neonatal growth and development. In order to clarify its developmental role, we have investigated, by immunohistochemistry, the localization of EGF and the time of its first appearance in various organs from a series of 25 midtrimester human fetuses with a gestational age ranging from 13 to 22 weeks. The first detectable EGF immunoreactivity occurred in week 15-16 fetuses in the placenta, the skin, the distal tubules of the kidney, the surface epithelium of the stomach, and the tips of the small intestinal villi, as well as in a few Paneth cells. Glandular structures, such as the glands of the cardia and the pyloric part of the stomach, Brunner's glands of the duodenum, the pancreas, and the submucous glands of the trachea, showed positive EGF immunoreactivity later (week 17). Thus, apart from the kidney, staining of the surface epithelia seems to precede staining of the EGF-producing glandular structures and EGF is not present in the glands before these have already differentiated.",
keywords = "Adult, Epidermal Growth Factor, Female, Fetus, Humans, Immunohistochemistry, Intestine, Small, Kidney, Placenta, Pregnancy, Pregnancy Trimester, Second, Skin, Time Factors",
author = "Poulsen, {Steen Seier} and N Kryger-Baggesen and Ebba Nex{\o}",
year = "1996",
month = feb,
language = "English",
volume = "105",
pages = "111--7",
journal = "Histochemistry and Cell Biology",
issn = "0948-6143",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Immunohistochemical localization of epidermal growth factor in the second-trimester human fetus

AU - Poulsen, Steen Seier

AU - Kryger-Baggesen, N

AU - Nexø, Ebba

PY - 1996/2

Y1 - 1996/2

N2 - Epidermal growth factor (EGF) is considered to be important in mammalian neonatal growth and development. In order to clarify its developmental role, we have investigated, by immunohistochemistry, the localization of EGF and the time of its first appearance in various organs from a series of 25 midtrimester human fetuses with a gestational age ranging from 13 to 22 weeks. The first detectable EGF immunoreactivity occurred in week 15-16 fetuses in the placenta, the skin, the distal tubules of the kidney, the surface epithelium of the stomach, and the tips of the small intestinal villi, as well as in a few Paneth cells. Glandular structures, such as the glands of the cardia and the pyloric part of the stomach, Brunner's glands of the duodenum, the pancreas, and the submucous glands of the trachea, showed positive EGF immunoreactivity later (week 17). Thus, apart from the kidney, staining of the surface epithelia seems to precede staining of the EGF-producing glandular structures and EGF is not present in the glands before these have already differentiated.

AB - Epidermal growth factor (EGF) is considered to be important in mammalian neonatal growth and development. In order to clarify its developmental role, we have investigated, by immunohistochemistry, the localization of EGF and the time of its first appearance in various organs from a series of 25 midtrimester human fetuses with a gestational age ranging from 13 to 22 weeks. The first detectable EGF immunoreactivity occurred in week 15-16 fetuses in the placenta, the skin, the distal tubules of the kidney, the surface epithelium of the stomach, and the tips of the small intestinal villi, as well as in a few Paneth cells. Glandular structures, such as the glands of the cardia and the pyloric part of the stomach, Brunner's glands of the duodenum, the pancreas, and the submucous glands of the trachea, showed positive EGF immunoreactivity later (week 17). Thus, apart from the kidney, staining of the surface epithelia seems to precede staining of the EGF-producing glandular structures and EGF is not present in the glands before these have already differentiated.

KW - Adult

KW - Epidermal Growth Factor

KW - Female

KW - Fetus

KW - Humans

KW - Immunohistochemistry

KW - Intestine, Small

KW - Kidney

KW - Placenta

KW - Pregnancy

KW - Pregnancy Trimester, Second

KW - Skin

KW - Time Factors

M3 - Journal article

C2 - 8852432

VL - 105

SP - 111

EP - 117

JO - Histochemistry and Cell Biology

JF - Histochemistry and Cell Biology

SN - 0948-6143

IS - 2

ER -

ID: 47486915