Expression and function of the K+ channel KCNQ genes in human arteries
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Expression and function of the K+ channel KCNQ genes in human arteries. / Ng, Fu Liang; Davis, Alison J; Jepps, Thomas Andrew; Harhun, Maksym I; Yeung, Shuk Yin; Wan, Andrew; Reddy, Marcus; Melville, David; Nardi, Antonio; Khong, Teck K; Greenwood, Iain A.
I: British Journal of Pharmacology, Bind 162, Nr. 1, 01.2011, s. 42-53.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Expression and function of the K+ channel KCNQ genes in human arteries
AU - Ng, Fu Liang
AU - Davis, Alison J
AU - Jepps, Thomas Andrew
AU - Harhun, Maksym I
AU - Yeung, Shuk Yin
AU - Wan, Andrew
AU - Reddy, Marcus
AU - Melville, David
AU - Nardi, Antonio
AU - Khong, Teck K
AU - Greenwood, Iain A
N1 - © 2010 The Authors. British Journal of Pharmacology © 2010 The British Pharmacological Society.
PY - 2011/1
Y1 - 2011/1
N2 - KCNQ-encoded voltage-gated potassium channels (K(v) 7) have recently been identified as important anti-constrictor elements in rodent blood vessels but the role of these channels and the effects of their modulation in human arteries remain unknown. Here, we have assessed KCNQ gene expression and function in human arteries ex vivo.
AB - KCNQ-encoded voltage-gated potassium channels (K(v) 7) have recently been identified as important anti-constrictor elements in rodent blood vessels but the role of these channels and the effects of their modulation in human arteries remain unknown. Here, we have assessed KCNQ gene expression and function in human arteries ex vivo.
KW - Aged
KW - Arteries
KW - Female
KW - Humans
KW - Immunohistochemistry
KW - KCNQ Potassium Channels
KW - Male
KW - Middle Aged
KW - Polymerase Chain Reaction
KW - RNA, Messenger
U2 - 10.1111/j.1476-5381.2010.01027.x
DO - 10.1111/j.1476-5381.2010.01027.x
M3 - Journal article
C2 - 20840535
VL - 162
SP - 42
EP - 53
JO - British Journal of Pharmacology
JF - British Journal of Pharmacology
SN - 0007-1188
IS - 1
ER -
ID: 108539502