Epidermal growth factor in the rat lung

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Standard

Epidermal growth factor in the rat lung. / Raaberg, Lasse; Poulsen, Steen Seier; Nexø, Ebba.

I: Histochemistry, Bind 95, Nr. 5, 1991, s. 471-5.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Raaberg, L, Poulsen, SS & Nexø, E 1991, 'Epidermal growth factor in the rat lung', Histochemistry, bind 95, nr. 5, s. 471-5.

APA

Raaberg, L., Poulsen, S. S., & Nexø, E. (1991). Epidermal growth factor in the rat lung. Histochemistry, 95(5), 471-5.

Vancouver

Raaberg L, Poulsen SS, Nexø E. Epidermal growth factor in the rat lung. Histochemistry. 1991;95(5):471-5.

Author

Raaberg, Lasse ; Poulsen, Steen Seier ; Nexø, Ebba. / Epidermal growth factor in the rat lung. I: Histochemistry. 1991 ; Bind 95, Nr. 5. s. 471-5.

Bibtex

@article{d6acccb074d011dbbee902004c4f4f50,
title = "Epidermal growth factor in the rat lung",
abstract = "Epidermal Growth Factor (EGF) in pharmacological doses is able to induce precoccious lung maturation in rabbits and sheeps. As EGF is probably acting in a para- or autocrine way, we have searched for EGF in the lungs. We report EGF immunoreactivity to be present in the type II pneumocytes of the rat from a couple of days prior to birth and throughout life. Further, we report EGF immunoreactivity to be present in cells in the bronchi and the bronchioles from day 20-21 of gestation and throughout life. G-200 gelchromatography of lung extracts indicates that the EGF-reactive material is a high molecular weight form of EGF. Since previous studies have shown that EGF in pharmacological doses is able to promote lung maturation, our results may imply a physiological role for EGF in the lungs.",
keywords = "Animals, Animals, Newborn, Bronchi, Epidermal Growth Factor, Epithelium, Fetus, Gestational Age, Immunoenzyme Techniques, Lung, Molecular Weight, Pulmonary Alveoli, Rats, Rats, Inbred Strains",
author = "Lasse Raaberg and Poulsen, {Steen Seier} and Ebba Nex{\o}",
year = "1991",
language = "English",
volume = "95",
pages = "471--5",
journal = "Histochemistry",
issn = "0301-5564",
publisher = "Springer",
number = "5",

}

RIS

TY - JOUR

T1 - Epidermal growth factor in the rat lung

AU - Raaberg, Lasse

AU - Poulsen, Steen Seier

AU - Nexø, Ebba

PY - 1991

Y1 - 1991

N2 - Epidermal Growth Factor (EGF) in pharmacological doses is able to induce precoccious lung maturation in rabbits and sheeps. As EGF is probably acting in a para- or autocrine way, we have searched for EGF in the lungs. We report EGF immunoreactivity to be present in the type II pneumocytes of the rat from a couple of days prior to birth and throughout life. Further, we report EGF immunoreactivity to be present in cells in the bronchi and the bronchioles from day 20-21 of gestation and throughout life. G-200 gelchromatography of lung extracts indicates that the EGF-reactive material is a high molecular weight form of EGF. Since previous studies have shown that EGF in pharmacological doses is able to promote lung maturation, our results may imply a physiological role for EGF in the lungs.

AB - Epidermal Growth Factor (EGF) in pharmacological doses is able to induce precoccious lung maturation in rabbits and sheeps. As EGF is probably acting in a para- or autocrine way, we have searched for EGF in the lungs. We report EGF immunoreactivity to be present in the type II pneumocytes of the rat from a couple of days prior to birth and throughout life. Further, we report EGF immunoreactivity to be present in cells in the bronchi and the bronchioles from day 20-21 of gestation and throughout life. G-200 gelchromatography of lung extracts indicates that the EGF-reactive material is a high molecular weight form of EGF. Since previous studies have shown that EGF in pharmacological doses is able to promote lung maturation, our results may imply a physiological role for EGF in the lungs.

KW - Animals

KW - Animals, Newborn

KW - Bronchi

KW - Epidermal Growth Factor

KW - Epithelium

KW - Fetus

KW - Gestational Age

KW - Immunoenzyme Techniques

KW - Lung

KW - Molecular Weight

KW - Pulmonary Alveoli

KW - Rats

KW - Rats, Inbred Strains

M3 - Journal article

C2 - 1869448

VL - 95

SP - 471

EP - 475

JO - Histochemistry

JF - Histochemistry

SN - 0301-5564

IS - 5

ER -

ID: 301144