Sofia Hammami Bomholtz
Postdoc
Molecular Cardiology and Membrane Proteins
Blegdamsvej 3, 2200 København N.
- 2022
- Published
Whole-Exome Sequencing Implicates Neuronal Calcium Channel with Familial Atrial Fibrillation
Vad, Oliver Tim Bundgaard, Yan, Y., Denti, F., Ahlberg, Gustav, Refsgaard, L., Bomholtz, Sofia Hammami, Santos, J. L., Rasmussen, Simon, Haunsø, Stig, Svendsen, Jesper Hastrup, Christophersen, I. E., Schmitt, Nicole, Olesen, Morten Steen Salling & Bentzen, Bo Hjorth, 2022, In: Frontiers in Genetics. 13, 8 p., 806429.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Functional phenotype variations of two novel Kv 7.1 mutations identified in patients with Long QT syndrome
Bomholtz, Sofia Hammami, Refaat, M., Steffensen, Annette Buur, David, J., Espinosa, K., Nussbaum, R., Wojciak, J., Bentzen, Bo Hjorth, Scheinman, M. & Schmitt, Nicole, 2020, In: Pacing and Clinical Electrophysiology. 43, 2, p. 210-216 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of KCa2 Channels Decreased the Risk of Ventricular Arrhythmia in the Guinea Pig Heart During Induced Hypokalemia
Diness, J. G., Abildgaard, L., Bomholtz, Sofia Hammami, Skarsfeldt, M. A., Edvardsson, N., Sørensen, U. S., Grunnet, M. & Bentzen, B. H., 2020, In: Frontiers in Pharmacology. 11, 10 p., 749.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man
Bentzen, Bo Hjorth, Bomholtz, Sofia Hammami, Simó-Vicens, R., Folkersen, L., Abildgaard, L., Speerschneider, T., Muthukumarasamy, K. M., Edvardsson, N., Sørensen, U. S., Grunnet, M. & Diness, J. G., 2020, In: Frontiers in Pharmacology. 11, 610.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts
Kirchhoff, J. E., Skarsfeldt, M., Muthukumarasamy, K. M., Simó-Vicens, R., Bomholtz, Sofia Hammami, Abildgaard, L., Jespersen, Thomas, Sørensen, U. S., Grunnet, Morten, Bentzen, Bo Hjorth & Diness, Jonas Goldin, 2019, In: Frontiers in Pharmacology. 10, 13 p., 668.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
2,6-Bis(2-Benzimidazolyl)Pyridine (BBP) Is a Potent and Selective Inhibitor of Small Conductance Calcium-Activated Potassium (SK) Channels
Simó-Vicens, R., Bomholtz, Sofia Hammami, Sørensen, U. S. & Bentzen, Bo Hjorth, 3 Dec 2018, In: Frontiers in Pharmacology. 9, 1409.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Atrium-specific ion channels in the zebrafish: A role of Iin atrial repolarization
Skarsfeldt, M. A., Bomholtz, Sofia Hammami, Lundegaard, Pia Rengtved, Lopez-Izquierdo, A., Tristani-Firouzi, M. & Bentzen, Bo Hjorth, Jul 2018, In: Acta Physiologica (Print). 223, 3, 17 p., e13049.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PKD Phosphorylation as Novel Pathway of KV11.1 Regulation
Steffensen, Annette Buur, Bomholtz, Sofia Hammami, Andersen, M. N., Olsen, Jesper Velgaard, Mutsaers, N., Lundegaard, Pia Rengtved, Lundby, Alicia & Schmitt, Nicole, 2018, In: Cellular Physiology and Biochemistry. 47, 4, p. 1742-1750 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Profiling of GABAA and GABAB receptor expression in the myometrium of the human uterus
Söderhielm, P. C., Klein, A. B., Bomholtz, Sofia Hammami & Jensen, Anders A., 2018, In: Life Sciences. 214, p. 145-152Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Diness, Jonas Goldin, Skibsbye, L., Simó-Vicens, R., Louro Larupa dos Santos, J., Lundegaard, Pia Rengtved, Citerni, C., Sauter, D. R. P., Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, U. S., Jespersen, Thomas, Grunnet, Morten & Bentzen, Bo Hjorth, 10 Oct 2017, In: Circulation: Arrhythmia and Electrophysiology. 10, 19 p., e005125.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts
Skarsfeldt, M. A., Jepps, Thomas Andrew Qvistgaard, Bomholtz, Sofia Hammami, Abildgaard, L., Sørensen, U. S., Gregers, E., Svendsen, Jesper Hastrup, Diness, J. G., Grunnet, M., Schmitt, Nicole, Olesen, Søren-Peter & Bentzen, Bo Hjorth, Apr 2016, In: Pfluegers Archiv. 468, 4, p. 643-654 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium
Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, Sofia Hammami, Nielsen, Morten Schak, Grunnet, Morten, Bentzen, Bo Hjorth & Jespersen, Thomas, Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Cell volume changes regulate Slick (Slo2.1), but not Slack (Slo2.2) K+ channels
Tejada, M. D. L. A., Stople, K., Bomholtz, Sofia Hammami, Meinild, A., Poulsen, A. N. & Klærke, Dan Arne, 2014, In: P L o S One. 9, 10, p. 1-8 8 p., e110833.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein
Andersen, M. N., Krzystanek, K., Petersen, F., Bomholtz, Sofia Hammami, Olesen, Søren-Peter, Abriel, H., Jespersen, Thomas & Rasmussen, Hanne Borger, 8 Nov 2013, In: The Journal of Biological Chemistry. 288, 52, p. 36841-54 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Purinergic signalling - a possible mechanism for KCNQ1 channel response to cell volume challenges
Bomholtz, Sofia Hammami, Willumsen, N. J., Meinild, A., Klærke, Dan Arne & Novak, Ivana, 2013, In: Acta Physiologica (Print). 207, 3, p. 503-515 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
Evidence for a common pharmacological interaction site on K(Ca)2 channels providing both selective activation and selective inhibition of the human K(Ca)2.1 subtype
Hougaard, C., Bomholtz, Sofia Hammami, Eriksen, B. L., Sørensen, U. S., Jensen, Marianne Lund, Strøbæk, D., Christophersen, P. & Bomholtz, Sofia Hammami, Feb 2012, In: Molecular Pharmacology. 81, 2, p. 210-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Submitted
Upregulation of KCNQ1 currents by the KCNE1 beta subunit is not caused by insertion of KCNQ1 into the membrane
Bomholtz, Sofia Hammami, Willumsen, N. & Klærke, Dan Arne, 2011, (Submitted). 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- 2010
- Published
KCNE1-induced increase in KCNQ1 currents is not mediated through enhanced membrane expression
Bomholtz, Sofia Hammami, Willumsen, N. J. & Klærke, Dan Arne, Apr 2010, In: The FASEB Journal. 24, 610.6Research output: Contribution to journal › Conference abstract in journal › Research
- Published
KCNQ1 channel response to cell volume changes is not mediated by ATP release
Bomholtz, Sofia Hammami, Willumsen, N., Novak, Ivana & Klærke, Dan Arne, 2010, In: Acta Physiologica Scandinavica. Supplementum. 198, Suppl 677, p. 213 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Mechanism for strict regulation of certain K+ channels by small, fast changes in cell volume
Tejada, M. D. L. A., Stolpe, K., Bomholtz, Sofia Hammami, Willumsen, N. J., Poulsen, A. N. & Klærke, Dan Arne, 2010, In: Biophysical Journal. Supp. 1, p. 534aResearch output: Contribution to journal › Conference abstract in journal › Research
- Published
Mechanisms underlying KCNQ1channel cell volume sensitivity
Bomholtz, Sofia Hammami, 2010, Biologisk Institut: Museum Tusculanum. 112 p.Research output: Book/Report › Ph.D. thesis › Research
- 2009
- Published
Cell volume and membrane stretch independently control K+ channel activity
Bomholtz, Sofia Hammami, Willumsen, N. J., Olsen, H. L., Morera, F. J., Latorre, R. & Klærke, Dan Arne, 2009, In: Journal of Physiology. 587, Pt 10, p. 2225-31 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction of purinergic receptors, K+ channels and aquaporins in cell volume regulation
Bomholtz, Sofia Hammami, Novak, Ivana, Willumsen, N. J. & Klærke, Dan Arne, 2009, In: Journal of Physiological Sciences. 1, p. 387 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- 2007
- Published
Cell volume and membrane stretch independently control K+ channel activity
Bomholtz, Sofia Hammami, Willumsen, N. J. & Klærke, Dan Arne, 2007, In: The FASEB Journal. 5, p. A539-A539 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
ID: 40446292
Most downloads
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933
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Cell volume changes regulate Slick (Slo2.1), but not Slack (Slo2.2) K+ channels
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
349
downloads
Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
205
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2,6-Bis(2-Benzimidazolyl)Pyridine (BBP) Is a Potent and Selective Inhibitor of Small Conductance Calcium-Activated Potassium (SK) Channels
Research output: Contribution to journal › Journal article › Research › peer-review
Published