Lykke Sylow
Associate Professor - Promotion Programme
Molecular Metabolism in Cancer and Ageing
Blegdamsvej 3
2200 København N
- Published
AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
Raun, Steffen Henning, Ali, Mona Sadek, Han, X., Henriquez-Olguín, Carlos, Pham, Tang Cam Phung, Knudsen, Jonas Roland, Willemsen, A. C. H., Larsen, S., Jensen, Thomas Elbenhardt, Langen, R. & Sylow, Lykke, 7 Jun 2022, bioRxiv, 37 p.Research output: Working paper › Preprint
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Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo
Kleinert, Maximilian, Sylow, Lykke, Fazakerley, D. J., Krycer, J. R., Thomas, K. C., Oxbøll, A., Jordy, A. B., Jensen, Thomas Elbenhardt, Yang, G., Schjerling, P., Kiens, Bente, James, D. E., Ruegg, M. A. & Richter, Erik A., 2014, In: Molecular Metabolism. 3, 6, p. 630-641 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute systemic insulin intolerance does not alter the response of the Akt/GSK-3 pathway to environmental hypoxia in human skeletal muscle
D'Hulst, G., Sylow, Lykke, Hespel, P. & Deldicque, L., 2015, In: European Journal of Applied Physiology. 115, 6, p. 1219-1231 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adenosine monophosphate-activated protein kinase is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
Raun, Steffen Henning, Ali, Mona Sadek, Han, X., Henriquez-Olguín, Carlos, Pham, Tang Cam Phung, Meneses Valdés, Roberto Andrés, Knudsen, Jonas Roland, Willemsen, A. C. H., Larsen, Steen, Jensen, Thomas Elbenhardt, Langen, R. & Sylow, Lykke, 2023, In: Journal of Cachexia, Sarcopenia and Muscle. 14, 4, p. 1631-1647Research output: Contribution to journal › Journal article › Research › peer-review
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Akt and Rac1 signalling are jointly required for insulin-stimulated glucose uptake in skeletal muscle and downregulated in insulin resistance
Sylow, Lykke, Kleinert, Maximilian, Pehmøller, C., Prats Gavalda, Clara, Chiu, T. T., Klip, A., Richter, Erik A. & Jensen, Thomas Elbenhardt, 2014, In: Cellular Signalling. 26, 2, p. 323-331 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Body composition and metabolic characterization.
Kristensen, Jonas Møller, Kiens, Bente, Sylow, Lykke, Maarbjerg, S. J., Alsted, T. J., Frosig, C., Jeppesen, J., Jensen, T. E., Schjerling, Peter, Treebak, Jonas Thue, Wojtaszewski, Jørgen F P, Richter, Erik A. & Pehmoller, C., 2013Research output: Other contribution › Research
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Cancer causes dysfunctional insulin signaling and glucose transport in a muscle-type-specific manner
Raun, Steffen Henning, Knudsen, Jonas Roland, Han, X., Jensen, Thomas Elbenhardt & Sylow, Lykke, 2022, In: F A S E B Journal. 36, 3, 16 p., e22211.Research output: Contribution to journal › Journal article › Research › peer-review
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Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion
Han, X., Raun, Steffen Henning, Carlsson, Michala, Sjøberg, K. A., Henriquez-Olguín, Carlos, Ali, Mona Sadek, Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Møller, Lisbeth L V, Li, Z., Li, J., Jensen, Thomas Elbenhardt, Kiens, Bente & Sylow, Lykke, 2020, In: Metabolism - Clinical and Experimental. 105, 14 p., 154169.Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating follistatin and activin A and their regulation by insulin in obesity and type 2 diabetes
Sylow, Lykke, Vind, B. F., Kruse, R., Møller, P. M., Wojtaszewski, Jørgen F P, Richter, Erik A. & Højlund, K., 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 5, p. 1343-1354 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Conditioned media from MCF7 and BT474 breast cancer cells induce insulin resistance in skeletal muscle myotubes
Ali, Mona Sadek, Han, X., Li, J., Jäättelä, M. & Sylow, Lykke, 28 Jan 2020, bioRxiv.Research output: Working paper › Preprint
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Contraction-stimulated glucose transport in muscle is controlled by AMPK and mechanical stress but not sarcoplasmatic reticulum Ca2+ release
Jensen, Thomas Elbenhardt, Sylow, Lykke, Rose, A. J., Madsen, A. L. B., Angin, Y., Maarbjerg, S. J. & Richter, Erik A., 2014, In: Molecular Metabolism. 3, 7, p. 742-753 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Current advances in our understanding of exercise as medicine in metabolic disease
Sylow, Lykke & Richter, Erik A., 2019, In: Current Opinion in Physiology. 12, p. 12-19 8 p.Research output: Contribution to journal › Review › Research › peer-review
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Current understanding of increased insulin sensitivity after exercise - emerging candidates
Maarbjerg, S. J., Sylow, Lykke & Richter, Erik A., 2011, In: Acta Physiologica. 202, 3, p. 323-335 13 p.Research output: Contribution to journal › Review › Research › peer-review
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Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise
Henriquez-Olguín, Carlos, Knudsen, Jonas Roland, Raun, Steffen Henning, Li, Z., Kellezi, Emilie Dalbram, Treebak, Jonas Thue, Sylow, Lykke, Holmdahl, R., Richter, Erik A., Jaimovich, E. & Jensen, Thomas Elbenhardt, 2019, In: Nature Communications. 10, 11 p., 4623.Research output: Contribution to journal › Journal article › Research › peer-review
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Decreased spontaneous activity in AMPK alpha 2 muscle specific kinase dead mice is not caused by changes in brain dopamine metabolism
Møller, Lisbeth L V, Sylow, Lykke, Gøtzsche, C. R., Serup, A. K. L., Christiansen, S. H., Weikop, Pia, Kiens, Bente, Woldbye, David Paul Drucker & Richter, Erik A., 2016, In: Physiology & Behavior. 164, Part A, p. 300-305 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deletion of skeletal muscle SOCS3 prevents insulin resistance in obesity
Beck Jørgensen, S., O'Neill, H. M., Sylow, Lykke, Honeyman, J., Hewitt, K. A., Palanivel, R., Fullerton, M. D., Öberg, L., Balendran, A., Galic, S., van der Poel, C., Trounce, I. A., Lynch, G. S., Schertzer, J. D. & Steinberg, G. R., 2013, In: Diabetes. 62, 1, p. 56-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential effects of high-fat diet and exercise training on bone and energy metabolism
Picke, A., Sylow, Lykke, Møller, Lisbeth L V, Kjøbsted, Rasmus, Schmidt, F. N., Steejn, M. W., Salbach-Hirsch, J., Hofbauer, C., Blüher, M., Saalbach, A., Busse, B., Rauner, M. & Hofbauer, L. C., 2018, In: Bone. 116, p. 120-134 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Disruption of mitochondrial dynamics triggers muscle inflammation through interorganellar contacts and mitochondrial DNA mislocation
Irazoki, Andrea, Gordaliza-Alaguero, I., Frank, E., Giakoumakis, N. N., Seco, J., Palacín, M., Gumà, A., Sylow, Lykke, Sebastián, D. & Zorzano, A., 2023, In: Nature Communications. 14, 1, 19 p., 108.Research output: Contribution to journal › Journal article › Research › peer-review
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Editorial: Skeletal muscle immunometabolism
Trollet, C., Cheng, A. J., Sylow, Lykke, Batista, M. L. & Pillon, N. J., 2021, In: Frontiers in Physiology. 12, 3 p., 683088.Research output: Contribution to journal › Editorial › Research
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Effect of hypoxic exercise on glucose tolerance in healthy and pre-diabetic adults
De Groote, E., Britto, F. A., Balan, E., Warnier, G., Thissen, J., Nielens, H., Sylow, Lykke & Deldicque, L., 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, 1, p. E43-E54 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of Roux-en-Y gastric bypass on circulating follistatin, activin A, and peripheral ActRIIB signaling in humans with obesity and type 2 diabetes
Pham, Tang Cam Phung, Bojsen-Møller, K. N., Madsbad, Sten, Wojtaszewski, Jørgen F P, Richter, Erik A. & Sylow, Lykke, 2021, In: International Journal of Obesity. 45, p. 316-325 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endothelial mechanotransduction proteins and vascular function are altered by dietary sucrose supplementation in healthy young male subjects
Gliemann, Lasse, Rytter, N., Lindskrog, M., Slingsby, M. H. L., Åkerström, T., Sylow, Lykke, Richter, Erik A. & Hellsten, Ylva, 2017, In: Journal of Physiology. 595, 16, p. 5557-5571 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exercise - a panacea of metabolic dysregulation in cancer: Physiological and molecular insights
Raun, Steffen Henning, Buch-Larsen, K., Schwarz, Peter & Sylow, Lykke, 2021, In: International Journal of Molecular Sciences. 22, 7, 23 p., 3469.Research output: Contribution to journal › Review › Research › peer-review
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Exercise increases human skeletal muscle insulin sensitivity via coordinated increases in microvascular perfusion and molecular signaling
Sjøberg, K. A., Frøsig, C., Kjøbsted, Rasmus, Sylow, Lykke, Kleinert, Maximilian, Betik, A. C., Shaw, C. S., Kiens, Bente, Wojtaszewski, Jørgen F P, Rattigan, S., Richter, Erik A. & McConell, G. K., 2017, In: Diabetes. 66, 6, p. 1501-1510 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise increases phosphorylation of the putative mTORC2 activity readout NDRG1 in human skeletal muscle
Knudsen, Jonas Roland, Persson, Kaspar Wredstrøm, Meister, J., Carl, Christian Strini, Raun, Steffen Henning, Andersen, Nicoline Resen, Sylow, Lykke, Kiens, Bente, Jensen, Thomas Elbenhardt, Richter, Erik A. & Kleinert, Maximilian, 2022, In: American Journal of Physiology: Endocrinology and Metabolism. 322, 1, p. E63-E73 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 19375571
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mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
218
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Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training
Research output: Contribution to journal › Journal article › Research › peer-review
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161
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Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise
Research output: Contribution to journal › Journal article › Research › peer-review
Published