Publications

2002

"Sausage-string" appearance of arteries and arterioles can be caused by an instability of the blood vessel wall.
Jacobsen, J. C. B., Beierholm, U., Mikkelsen, R., Gustafsson, F., Alstrøm, P. & Holstein-Rathlou, N-H. 2002 I : American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 283, 5, s. R1118-30

2003

A model of physical factors in the structural adaptation of microvascular networks in normotension and hypertension.
Jacobsen, J. C. B., Gustafsson, F. & Holstein-Rathlou, N-H. 2003 I : Physiological Measurement. 24, 4, s. 891-912 21 s.

Brief communication: age and fractal dimensions of human sagittal and coronal sutures.
Lynnerup, N. & Jacobsen, J. C. B. 2003 I : American Journal of Physical Anthropology. 121, 4, s. 332-6 4 s.

2007

A model of smooth muscle cell synchronization in the arterial wall.
Jacobsen, J. C. B., Aalkjaer, C., Nilsson, H., Matchkov, V. V., Freiberg, J. & Holstein-Rathlou, N-H. 2007 I : American Journal of Physiology: Heart and Circulatory Physiology. 293, 1, s. H229-37

Activation of a cGMP-sensitive calcium-dependent chloride channel may cause transition from calcium waves to whole cell oscillations in smooth muscle cells.
Jacobsen, J. C. B., Aalkjaer, C., Nilsson, H., Matchkov, V. V., Freiberg, J. & Holstein-Rathlou, N-H. 2007 I : American Journal of Physiology: Heart and Circulatory Physiology. 293, 1, s. H215-28

Characteristics of blood vessels forming "sausages-on-a-string" patterns during hypertension
Beierholm, U. R., Jacobsen, J. C. B., Von Holstein-Rathlou, N-H. & Alstrom, P. 2007 I : Physica A: Statistical Mechanics and its Applications. 376, s. 387-393 6 s.

2008

A mechanism for arteriolar remodeling based on maintenance of smooth muscle cell activation.
Jacobsen, J. C. B., Mulvany, M. J. & Holstein-Rathlou, N-H. 2008 I : American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 294, 4, s. R1379-89

Heterogeneity and weak coupling may explain the synchronization characteristics of cells in the arterial wall.
Jacobsen, J. C. B., Aalkjaer, C., Matchkov, V. V., Nilsson, H., Holstein-Rathlou, N-H. & Freiberg, J. J. 2008 I : Philosophical Transactions. Series A : Mathematical, physical, and engineering science. 366, 1880, s. 3483-502 19 s.

2009

A tissue in the tissue: models of microvascular plasticity
Jacobsen, J. C. B., Hornbech, M. S. & Holstein-Rathlou, N-H. 2009 I : European Journal of Pharmaceutical Sciences. 36, 1, s. 51-61 10 s.

2011

Bestrophin is important for the rhythmic but not the tonic contraction in rat mesenteric small arteries
Broegger, T., Jacobsen, J. C. B., Secher Dam, V., Boedtkjer, D. M. B., Kold-Petersen, H. H., Pedersen, F. S., Aalkjaer, C. & Matchkov, V. 2011 I : Cardiovascular Research. 91, 4, s. 685-93 9 s.

Functional Modeling of the Shift in Cellular Calcium Dynamics at the Onset of Synchronization in Smooth Muscle Cells
Postnov, D. E., Brings Jacobsen, J. C., von Holstein-Rathlou, N-H. & Sosnovtseva, O. 9 mar 2011 I : Bulletin of Mathematical Biology.

Significance of microvascular remodelling for the vascular flow reserve in hypertension
Jacobsen, J. C. B., Hornbech, M. S. & von Holstein-Rathlou, N-H. 6 feb 2011 I : Interface Focus. 1, 1, s. 117-31 15 s.

2012

A life under pressure: circumferential stress in the microvascular wall
Jacobsen, J. C. B. & von Holstein-Rathlou, N-H. 2012 I : Basic & Clinical Pharmacology & Toxicology Online. 110, 1, s. 26-34 9 s.

Applicability of cable theory to vascular conducted responses
Hald, B. O., Jensen, L. J., Sørensen, P. G., von Holstein-Rathlou, N-H. & Jacobsen, J. C. B. 2012 I : Biophysical Journal. 102, 6, s. 1352-1362 11 s.

BKCa and KV channels limit conducted vasomotor responses in rat mesenteric terminal arterioles
Hald, B. O., Jacobsen, J. C. B., Braunstein, T. H., Inoue, R., Ito, Y., Sørensen, P. G., von Holstein-Rathlou, N-H. & Jensen, L. J. 2012 I : Pfluegers Archiv. 463, 2, s. 279-295 17 s.

Dynamic adaption of vascular morphology
Okkels, F. & Jacobsen, J. C. B. 2012 I : Frontiers in Physiology. 3, s. 390

Estimation of the effective intercellular diffusion coefficient in cell monolayers coupled by gap junctions
Olesen, N. E., Hofgaard, J. P., von Holstein-Rathlou, N-H., Nielsen, M. S. & Jacobsen, J. C. B. 2012 I : European Journal of Pharmaceutical Sciences. 46, 4, s. 222-32 11 s.

The nanostructure of myoendothelial junctions contributes to signal rectification between endothelial and vascular smooth muscle cells
Brasen, J. C., Jacobsen, J. C. B. & von Holstein-Rathlou, N-H. 2012 I : P L o S One. 7, 4, s. e33632

2013

From excitability to oscillations: A case study in vasomotion
Postnov, D. E., Neganova, A. Y., Jacobsen, J. C. B., von Holstein-Rathlou, N-H. & Sosnovtseva, O. okt 2013 I : European Physical Journal. Special Topics. 222, 10, s. 2667-2676 10 s.

2014

Less is more: minimal expression of myoendothelial gap junctions optimizes cell-cell communication in virtual arterioles.
Hald, B. O., Jacobsen, J. C. B., Sandow, S. L., von Holstein-Rathlou, N-H. & Welsh, D. G. 1 aug 2014 I : J. of Physiol.1, 592(Pt 15), s. 3243-55

Gap junctions suppress electrical but not [Ca(2+)] heterogeneity in resistance arteries.
Hald BO, Welsh DG, Holstein-Rathlou NH, Jacobsen J.C.B.
Biophys J. 2014 Nov 18;107(10):2467-76.

2015

Origins of variation in conducted vasomotor responses.
Hald BO, Welsh DG, Holstein-Rathlou NH, Jacobsen JC.
Pflugers Arch. 2015;467(10):2055-67.

Conducted vasoreactivity: the dynamical point of view.
Postnov DE, Neganova AY, Sosnovtseva OV, Holstein-Rathlou NH, Jacobsen J.C.B.
Bull Math Biol. 2015;77(1):230-49.

Influence of Connexin40 on the renal myogenic response in murine afferent arterioles.
Jacobsen JC, Sorensen CM.
Physiol Rep. 2015;3(5).

Papers currently in review:

1) Vascular flow reserve as a link between long term blood pressure level and physical performance capacity in vertebrates

Christian Bo Poulsen, Mads Damkjær, Bjørn Olav Hald, Tobias Wang, Niels-Henrik Holstein-Rathlou and Jens Christian Brings Jacobsen

(Reviewing journal: Physiol Rep)

2) Laser speckle analysis of retinal vascular dynamics

Anastasiia Y. Neganova, Dmitry D. Postnov, Jens Christian B. Jacobsen and Olga Sosnovtseva

(Reviewing journal: Biomedical Optics Express)

Book chapters

Microvascular Plasticity

Jacobsen, J. C. B., Olesen, N. E. & von Holstein-Rathlou, N-H. 2012 Biosimulation in Biomedical Research, Health Care and Drug Development Biosimulation in Biomedical Research, Health Care and Drug Development. Mosekilde, E., Sosnovtseva, O. & Rostami-Hodjegan, A. (red.). Wien: Springer, Kap. 11, s. 237-252 16 s.

Modeling Ca2+ Microdomains

Brasen, J. C., Jacobsen, J. C. B. & von Holstein-Rathlou, N-H. 2012 Biosimulation in Biomedical Research, Health Care and Drug Development Biosimulation in Biomedical Research, Health Care and Drug Development. Mosekilde, E., Sosnovtseva, O. & Rostami-Hodjegan, A. (red.). Wien: Springer, Kap. 9, s. 201-218 18 s.

Synchronization of cellular contractions in the arteriolar wall

Jacobsen, J. C. B., Hald, B. O., Brasen, J. C. & von Holstein-Rathlou, N-H. 2012 Biosimulation in biomedical research, health care and drug development biosimulation in Biomedical Research, Health Care and Drug Development. Mosekilde, E., Sosnovtseva, O. & Rostami-Hodjegan, A. (red.). Springer, Kap. 10, s. 219-236 18 s.