Project supervision

Examples of accomplished bachelor and Master projects in various study courses (Medicine, Biochemistry, Medicine and Technology, Molecular Biomedicine, Human Biology).

Supervision of Master thesis projects in the study courses Molecular Biomedicine and Human Biology

  • "Pharmacological characterization of the Kv7 channel mutants"
  • "Expression and Function of STIM1/2 and CRACM1/2 in native cells"
  • "Investigating the trafficking of potassium channel subunits"

Supervision of "practical" bachelor thesis projects in the study courses Molecular Biomedicine, Medical Engineering, and foreign study courses

  • "Silencing of Ankyrin-G and NaV1.x expression in cultured hippocampal neurons"
  • "A possible role for TRPM7 in cardiac fibrosis and atrial fibrillation - Assay development and drug target validation"
  • "Expression of Kv channels in INS-1 cells"
  • "Biology of KCNE4 channel subunits"
  • "Modulators of Ito channel function"
  • "Is KChIP2 a transcriptionally active entity?"
  • "Do N-terminal sequences play a role in trafficking of Kv7.1?"
  • "Improving interaction assays for ion channel proteins - Establishing the yeast two-hybrid split-ubiquitin system"
  • "Pharmacological modification of Kv11 channels"
  • "Investigating the trafficking of potassium channel subunits - Establishing a "KCNE interaction trap (KIT)" assay"
  • "Pharmacological characterization of the Kv7.4 (KCNQ4) mutant W242L and Western blot analysis of Kv7.4 expression"
  • "Elucidating the role of the PAS-domain in hERG channels: identification of interacting proteins."

Supervision of "theoretical" bachelor thesis projects in the study course Medicine

    • "Acquired Long QT-syndrome - Implications of Kv11.1 (hERG) blockade for drug development"
    • "Role of potassium channels in the etiology of schizophrenia"
    • "Sudden cardiac death in athletes - can it be prevented?"
    • "Molecular basis of Brugada syndrome"
      • "Prevalence of cardiac arrhythmia in Down syndrome patients"
      • "Association between epilepsy and arrhythmia"
      • "Analysis of the renal phenotype of a knock-out mouse model"
      • "The prevalence of type 2 diabetes among patients with single nucleotide polymorphisms in the KCNQ1 gene"
      • "The role of Kv2.1 in pancreatic physiology in relation to insulin secretion and type 2 diabetes"