Our vision 

Our vision is to prevent and cure type 1 and type 2 diabetes by targeting the inflammatory pathways leading to pancreatic beta-cell failure.

Our mission

Our mission is to define the transcriptional, translational and posttranslational responses of the pancreatic beta-cell to immune, inflammatory, metabolic and oxidative stress, with the aim of identifying novel therapeutic targets to be tested in preclinical models and clinical trials.

Our research strategy 

The Immuno-endocrinology lab employs an interdisciplinary and collaborative research strategy to unravel beta-cell transcriptional, translational and posttranslational responses to stress by two complementary approaches: a hypothesis-driven approach evolving from new discoveries in the lab and an unbiased screening approach employing systems biology and using functional genomics, transcriptomics, proteomics and post-translatomics.

Our tactics 

Our experimental tactics utilise systems biology, bioinformatics, and in silico model-ling, cell-free and cell-based in vitro models, ex vivo and in vivo studies in induced and genetic experimental animals, and clinical trials and biomarker studies.

Our history

The immuno-endocrinology lab was launched in January 2014 as a consequence of a Faculty and Department decision to fill a full professorship in immuno-endocrinology.

Read about our research