Vascular Biology Group

Over one billion people worldwide are affected by high blood pressure (hypertension). Hypertension is a major risk factor in many diseases including heart failure, stroke, chronic kidney disease, erectile dysfunction and Alzheimer's disease. Importantly, 90% of the people with hypertension are genetically prone to developing high blood pressure, but relatively little is known about the mechanisms that underlie this susceptibility.

In the Vascular Biology Group we investigate blood vessels. We are interested in the cells that control the diameter of arteries, namely smooth muscle cells, which can contract and relax. In hypertension and atherosclerosis, hyper-contractility and restructuring of arterial smooth muscle cells leads to increased arterial tone and/or reduced blood flow. In the smooth muscle cells, several membrane proteins display altered function and expression, but without an understanding of how their membrane expression is controlled, development of new therapeutics to treat hypertension remains a distant dream. The group's research will continue to investigate trafficking mechanisms of specific membrane proteins, such as ion channels and receptors, that are dysregulated in vascular disease.






















































































Group leader

Group Leader

Thomas Qvistgaard Jepps
Associate Professor

Phone +45 3533 0972 

Group members

Name Title Phone E-mail
Anthony Michael Mozzicato PhD Fellow   E-mail
Joakim Armstrong Bastrup Postdoc   E-mail
Salomé Rognant PhD Fellow +4535337890 E-mail