15 October 2018

New, interesting article from Professor Birgitte Holst's research group

Publication

With her research group, Professor Birgitte Holst has published a new article entitled ”Translating biased signaling in the ghrelin receptor system into differential in vivo functions” in the journal ’PNAS’.


Together with her research group, Professor Birgitte Holst has published a new article. The article "Translating biased signaling in the ghrelin receptor system into differential in vivo functions" addresses how to develop and intelligently design new and innovative pharmaceuticals that only have the desired result without side effects. The article is published in the journal 'PNAS'.

In relation to obesity treatment, a frequent and very bothering side effect is development of nausea. Professor Birgitte Holst's research group have on this basis, characterized a type of pharmaceuticals (biased ligander) that favour a given cellular function that is important for the therapeutic, i.e. appetite suppressant, function, but not other functions of the product. This can help to improve pharmaceuticals for obesity treatment in the future.

Read the article