Only minor additional metabolic health benefits of high as opposed to moderate dose physical exercise in young, moderately overweight men

Research output: Contribution to journalJournal articlepeer-review

Standard

Only minor additional metabolic health benefits of high as opposed to moderate dose physical exercise in young, moderately overweight men. / Reichkendler, M H; Larsen, Mads Rosenkilde; Auerbach, P L; Agerschou, J; Nielsen, Maria Booth; Kjaer, A; Hoejgaard, L; Sjödin, A; Ploug, Thorkil; Stallknecht, B.

In: Obesity, Vol. 22, No. 5, 05.2014, p. 1220-32.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Reichkendler, MH, Larsen, MR, Auerbach, PL, Agerschou, J, Nielsen, MB, Kjaer, A, Hoejgaard, L, Sjödin, A, Ploug, T & Stallknecht, B 2014, 'Only minor additional metabolic health benefits of high as opposed to moderate dose physical exercise in young, moderately overweight men', Obesity, vol. 22, no. 5, pp. 1220-32. https://doi.org/10.1002/oby.20226

APA

Reichkendler, M. H., Larsen, M. R., Auerbach, P. L., Agerschou, J., Nielsen, M. B., Kjaer, A., Hoejgaard, L., Sjödin, A., Ploug, T., & Stallknecht, B. (2014). Only minor additional metabolic health benefits of high as opposed to moderate dose physical exercise in young, moderately overweight men. Obesity, 22(5), 1220-32. https://doi.org/10.1002/oby.20226

Vancouver

Reichkendler MH, Larsen MR, Auerbach PL, Agerschou J, Nielsen MB, Kjaer A et al. Only minor additional metabolic health benefits of high as opposed to moderate dose physical exercise in young, moderately overweight men. Obesity. 2014 May;22(5):1220-32. https://doi.org/10.1002/oby.20226

Author

Reichkendler, M H ; Larsen, Mads Rosenkilde ; Auerbach, P L ; Agerschou, J ; Nielsen, Maria Booth ; Kjaer, A ; Hoejgaard, L ; Sjödin, A ; Ploug, Thorkil ; Stallknecht, B. / Only minor additional metabolic health benefits of high as opposed to moderate dose physical exercise in young, moderately overweight men. In: Obesity. 2014 ; Vol. 22, No. 5. pp. 1220-32.

Bibtex

@article{606015be401b46eab792a8fd4a6240e7,
title = "Only minor additional metabolic health benefits of high as opposed to moderate dose physical exercise in young, moderately overweight men",
abstract = "OBJECTIVE: The dose-response effects of exercise training on insulin sensitivity, metabolic risk, and quality of life were examined.METHODS: Sixty-one healthy, sedentary (VO₂max: 35 ± 5 ml/kg/min), moderately overweight (BMI: 27.9 ± 1.8), young (age: 29 ± 6 years) men were randomized to sedentary living (sedentary control group; n = 18), moderate (moderate dose training group [MOD]: 300 kcal/day, n = 21), or high (high dose training group [HIGH]: 600 kcal/day, n = 22) dose physical exercise for 11 weeks.RESULTS: The return rate for post-intervention testing was 82-94% across groups. Weekly exercise amounted to 2,004 ± 24 and 3,774 ± 68 kcal, respectively, in MOD and HIGH. Cardiorespiratory fitness increased (P < 0.001) 18 ± 3% in MOD and 17 ± 3% in HIGH, and fat percentage decreased (P < 0.001) similarly in both exercise groups (MOD: 32 ± 1 to 29 ± 1%; HIGH: 30 ± 1 to 27 ± 1%). Peripheral insulin sensitivity increased (P < 0.01) (MOD: 28 ± 7%; HIGH: 36 ± 8%) and the homeostasis model assessment of insulin resistance decreased (P < 0.05) (MOD: -17 ± 7%; HIGH: -18 ± 10%). The number of subjects meeting the criteria of the metabolic syndrome decreased by 78% in MOD (P < 0.01) and by 80% in HIGH (P < 0.05). General health assessed by questionnaire increased similarly in MOD (P < 0.05) and HIGH (P < 0.01).CONCLUSIONS: Only minor additional health benefits were found when exercising ∼3,800 as opposed to ∼2,000 kcal/week in young moderately overweight men. This finding may have important public health implications.",
author = "Reichkendler, {M H} and Larsen, {Mads Rosenkilde} and Auerbach, {P L} and J Agerschou and Nielsen, {Maria Booth} and A Kjaer and L Hoejgaard and A Sj{\"o}din and Thorkil Ploug and B Stallknecht",
note = "CURIS 2014 NEXS 401",
year = "2014",
month = may,
doi = "10.1002/oby.20226",
language = "English",
volume = "22",
pages = "1220--32",
journal = "Obesity",
issn = "1930-7381",
publisher = "Wiley-Blackwell",
number = "5",

}

RIS

TY - JOUR

T1 - Only minor additional metabolic health benefits of high as opposed to moderate dose physical exercise in young, moderately overweight men

AU - Reichkendler, M H

AU - Larsen, Mads Rosenkilde

AU - Auerbach, P L

AU - Agerschou, J

AU - Nielsen, Maria Booth

AU - Kjaer, A

AU - Hoejgaard, L

AU - Sjödin, A

AU - Ploug, Thorkil

AU - Stallknecht, B

N1 - CURIS 2014 NEXS 401

PY - 2014/5

Y1 - 2014/5

N2 - OBJECTIVE: The dose-response effects of exercise training on insulin sensitivity, metabolic risk, and quality of life were examined.METHODS: Sixty-one healthy, sedentary (VO₂max: 35 ± 5 ml/kg/min), moderately overweight (BMI: 27.9 ± 1.8), young (age: 29 ± 6 years) men were randomized to sedentary living (sedentary control group; n = 18), moderate (moderate dose training group [MOD]: 300 kcal/day, n = 21), or high (high dose training group [HIGH]: 600 kcal/day, n = 22) dose physical exercise for 11 weeks.RESULTS: The return rate for post-intervention testing was 82-94% across groups. Weekly exercise amounted to 2,004 ± 24 and 3,774 ± 68 kcal, respectively, in MOD and HIGH. Cardiorespiratory fitness increased (P < 0.001) 18 ± 3% in MOD and 17 ± 3% in HIGH, and fat percentage decreased (P < 0.001) similarly in both exercise groups (MOD: 32 ± 1 to 29 ± 1%; HIGH: 30 ± 1 to 27 ± 1%). Peripheral insulin sensitivity increased (P < 0.01) (MOD: 28 ± 7%; HIGH: 36 ± 8%) and the homeostasis model assessment of insulin resistance decreased (P < 0.05) (MOD: -17 ± 7%; HIGH: -18 ± 10%). The number of subjects meeting the criteria of the metabolic syndrome decreased by 78% in MOD (P < 0.01) and by 80% in HIGH (P < 0.05). General health assessed by questionnaire increased similarly in MOD (P < 0.05) and HIGH (P < 0.01).CONCLUSIONS: Only minor additional health benefits were found when exercising ∼3,800 as opposed to ∼2,000 kcal/week in young moderately overweight men. This finding may have important public health implications.

AB - OBJECTIVE: The dose-response effects of exercise training on insulin sensitivity, metabolic risk, and quality of life were examined.METHODS: Sixty-one healthy, sedentary (VO₂max: 35 ± 5 ml/kg/min), moderately overweight (BMI: 27.9 ± 1.8), young (age: 29 ± 6 years) men were randomized to sedentary living (sedentary control group; n = 18), moderate (moderate dose training group [MOD]: 300 kcal/day, n = 21), or high (high dose training group [HIGH]: 600 kcal/day, n = 22) dose physical exercise for 11 weeks.RESULTS: The return rate for post-intervention testing was 82-94% across groups. Weekly exercise amounted to 2,004 ± 24 and 3,774 ± 68 kcal, respectively, in MOD and HIGH. Cardiorespiratory fitness increased (P < 0.001) 18 ± 3% in MOD and 17 ± 3% in HIGH, and fat percentage decreased (P < 0.001) similarly in both exercise groups (MOD: 32 ± 1 to 29 ± 1%; HIGH: 30 ± 1 to 27 ± 1%). Peripheral insulin sensitivity increased (P < 0.01) (MOD: 28 ± 7%; HIGH: 36 ± 8%) and the homeostasis model assessment of insulin resistance decreased (P < 0.05) (MOD: -17 ± 7%; HIGH: -18 ± 10%). The number of subjects meeting the criteria of the metabolic syndrome decreased by 78% in MOD (P < 0.01) and by 80% in HIGH (P < 0.05). General health assessed by questionnaire increased similarly in MOD (P < 0.05) and HIGH (P < 0.01).CONCLUSIONS: Only minor additional health benefits were found when exercising ∼3,800 as opposed to ∼2,000 kcal/week in young moderately overweight men. This finding may have important public health implications.

U2 - 10.1002/oby.20226

DO - 10.1002/oby.20226

M3 - Journal article

C2 - 24339390

VL - 22

SP - 1220

EP - 1232

JO - Obesity

JF - Obesity

SN - 1930-7381

IS - 5

ER -

ID: 115731426