Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test

Research output: Contribution to journalJournal articlepeer-review

Standard

Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test. / Frandsen, Jacob; Pistoljevic, Nina; Quesada, Julia Prats; Amaro-Gahete, Francisco José; Ritz, Christian; Larsen, Steen; Dela, Flemming; Helge, Jørn Wulff.

In: Journal of Applied Physiology, Vol. 128, No. 3, 2020, p. 681-687.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Frandsen, J, Pistoljevic, N, Quesada, JP, Amaro-Gahete, FJ, Ritz, C, Larsen, S, Dela, F & Helge, JW 2020, 'Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test', Journal of Applied Physiology, vol. 128, no. 3, pp. 681-687. https://doi.org/10.1152/japplphysiol.00774.2019

APA

Frandsen, J., Pistoljevic, N., Quesada, J. P., Amaro-Gahete, F. J., Ritz, C., Larsen, S., Dela, F., & Helge, J. W. (2020). Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test. Journal of Applied Physiology, 128(3), 681-687. https://doi.org/10.1152/japplphysiol.00774.2019

Vancouver

Frandsen J, Pistoljevic N, Quesada JP, Amaro-Gahete FJ, Ritz C, Larsen S et al. Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test. Journal of Applied Physiology. 2020;128(3):681-687. https://doi.org/10.1152/japplphysiol.00774.2019

Author

Frandsen, Jacob ; Pistoljevic, Nina ; Quesada, Julia Prats ; Amaro-Gahete, Francisco José ; Ritz, Christian ; Larsen, Steen ; Dela, Flemming ; Helge, Jørn Wulff. / Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test. In: Journal of Applied Physiology. 2020 ; Vol. 128, No. 3. pp. 681-687.

Bibtex

@article{a97542970a734be8942b13b2d92e8f78,
title = "Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test",
abstract = "Female sex hormones fluctuate in a predictable manner throughout the menstrual cycle in eumenorrheic women. In studies conducted in both animal and humans, estrogen and progesterone have been found to exert individual metabolic effects during both rest and exercise, suggesting that estrogen may cause an increase in fat oxidation during exercise. However, not all studies find these metabolic changes with the natural physiological variation in the sex hormones. To date, no studies have investigated whether whole body peak fat oxidation rate (PFO) and maximal fat oxidation intensity (FATmax) are affected at different time points [mid-follicular (MF), late-follicular (LF), and mid-luteal (ML)] in the menstrual cycle, where plasma estrogen and progesterone are either at their minimum or maximum. We hypothesized that an increased plasma estrogen concentration together with low progesterone concentration in LF would result in a modest but significant increase in PFO. We found no differences in body weight, body composition, or peak oxygen uptake ({\.V}o2peak) between any of the menstrual phases in the 19 healthy, young eumenorrheic women included in this study. PFO [MF: 0.379 (0.324-0.433) g/min; LF: 0.375 (0.329-0.421) g/min; ML: 0.382 (0.337-0.442) g/min; mean ± (95% CI)] and resting plasma free fatty acid concentrations [MF: 392 (293-492) µmol/l; LF: 477 (324-631) µmol/l; ML: 396 (285-508) µmol/L] were also similar across the menstrual cycle phases. Contrary to our hypothesis, we conclude that the naturally occurring fluctuations in the sex hormones estrogen and progesterone do not affect the whole body PFO and FATmax in young eumenorrheic women measured during a graded exercise test.NEW & NOTEWORTHY Menstrual cycle phase does not affect the peak fat oxidation rate during a graded exercise test. Natural physiological fluctuations in estrogen do not increase peak fat oxidation rate. FATmax is not influenced by menstrual cycle phase in healthy, young eumenorrheic women.",
keywords = "Faculty of Science, Estrogen, Fat oxidation, Female, Progesterone, Sex hormones",
author = "Jacob Frandsen and Nina Pistoljevic and Quesada, {Julia Prats} and Amaro-Gahete, {Francisco Jos{\'e}} and Christian Ritz and Steen Larsen and Flemming Dela and Helge, {J{\o}rn Wulff}",
note = "CURIS 2020 NEXS 064",
year = "2020",
doi = "10.1152/japplphysiol.00774.2019",
language = "English",
volume = "128",
pages = "681--687",
journal = "Journal of Applied Physiology",
issn = "8750-7587",
publisher = "American Physiological Society",
number = "3",

}

RIS

TY - JOUR

T1 - Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test

AU - Frandsen, Jacob

AU - Pistoljevic, Nina

AU - Quesada, Julia Prats

AU - Amaro-Gahete, Francisco José

AU - Ritz, Christian

AU - Larsen, Steen

AU - Dela, Flemming

AU - Helge, Jørn Wulff

N1 - CURIS 2020 NEXS 064

PY - 2020

Y1 - 2020

N2 - Female sex hormones fluctuate in a predictable manner throughout the menstrual cycle in eumenorrheic women. In studies conducted in both animal and humans, estrogen and progesterone have been found to exert individual metabolic effects during both rest and exercise, suggesting that estrogen may cause an increase in fat oxidation during exercise. However, not all studies find these metabolic changes with the natural physiological variation in the sex hormones. To date, no studies have investigated whether whole body peak fat oxidation rate (PFO) and maximal fat oxidation intensity (FATmax) are affected at different time points [mid-follicular (MF), late-follicular (LF), and mid-luteal (ML)] in the menstrual cycle, where plasma estrogen and progesterone are either at their minimum or maximum. We hypothesized that an increased plasma estrogen concentration together with low progesterone concentration in LF would result in a modest but significant increase in PFO. We found no differences in body weight, body composition, or peak oxygen uptake (V̇o2peak) between any of the menstrual phases in the 19 healthy, young eumenorrheic women included in this study. PFO [MF: 0.379 (0.324-0.433) g/min; LF: 0.375 (0.329-0.421) g/min; ML: 0.382 (0.337-0.442) g/min; mean ± (95% CI)] and resting plasma free fatty acid concentrations [MF: 392 (293-492) µmol/l; LF: 477 (324-631) µmol/l; ML: 396 (285-508) µmol/L] were also similar across the menstrual cycle phases. Contrary to our hypothesis, we conclude that the naturally occurring fluctuations in the sex hormones estrogen and progesterone do not affect the whole body PFO and FATmax in young eumenorrheic women measured during a graded exercise test.NEW & NOTEWORTHY Menstrual cycle phase does not affect the peak fat oxidation rate during a graded exercise test. Natural physiological fluctuations in estrogen do not increase peak fat oxidation rate. FATmax is not influenced by menstrual cycle phase in healthy, young eumenorrheic women.

AB - Female sex hormones fluctuate in a predictable manner throughout the menstrual cycle in eumenorrheic women. In studies conducted in both animal and humans, estrogen and progesterone have been found to exert individual metabolic effects during both rest and exercise, suggesting that estrogen may cause an increase in fat oxidation during exercise. However, not all studies find these metabolic changes with the natural physiological variation in the sex hormones. To date, no studies have investigated whether whole body peak fat oxidation rate (PFO) and maximal fat oxidation intensity (FATmax) are affected at different time points [mid-follicular (MF), late-follicular (LF), and mid-luteal (ML)] in the menstrual cycle, where plasma estrogen and progesterone are either at their minimum or maximum. We hypothesized that an increased plasma estrogen concentration together with low progesterone concentration in LF would result in a modest but significant increase in PFO. We found no differences in body weight, body composition, or peak oxygen uptake (V̇o2peak) between any of the menstrual phases in the 19 healthy, young eumenorrheic women included in this study. PFO [MF: 0.379 (0.324-0.433) g/min; LF: 0.375 (0.329-0.421) g/min; ML: 0.382 (0.337-0.442) g/min; mean ± (95% CI)] and resting plasma free fatty acid concentrations [MF: 392 (293-492) µmol/l; LF: 477 (324-631) µmol/l; ML: 396 (285-508) µmol/L] were also similar across the menstrual cycle phases. Contrary to our hypothesis, we conclude that the naturally occurring fluctuations in the sex hormones estrogen and progesterone do not affect the whole body PFO and FATmax in young eumenorrheic women measured during a graded exercise test.NEW & NOTEWORTHY Menstrual cycle phase does not affect the peak fat oxidation rate during a graded exercise test. Natural physiological fluctuations in estrogen do not increase peak fat oxidation rate. FATmax is not influenced by menstrual cycle phase in healthy, young eumenorrheic women.

KW - Faculty of Science

KW - Estrogen

KW - Fat oxidation

KW - Female

KW - Progesterone

KW - Sex hormones

U2 - 10.1152/japplphysiol.00774.2019

DO - 10.1152/japplphysiol.00774.2019

M3 - Journal article

C2 - 32078462

VL - 128

SP - 681

EP - 687

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

SN - 8750-7587

IS - 3

ER -

ID: 237756948