Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes
Research output: Contribution to journal › Journal article › peer-review
Standard
Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes. / Flethøj, M.; Schwarzwald, C. C.; Haugaard, M. M.; Carstensen, H.; Kanters, J. K.; Olsen, L. H.; Buhl, R.
In: Journal of Veterinary Internal Medicine, Vol. 30, No. 4, 07.2016, p. 1260-1269.Research output: Contribution to journal › Journal article › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes
AU - Flethøj, M.
AU - Schwarzwald, C. C.
AU - Haugaard, M. M.
AU - Carstensen, H.
AU - Kanters, J. K.
AU - Olsen, L. H.
AU - Buhl, R.
PY - 2016/7
Y1 - 2016/7
N2 - Background: Prolonged exercise in human athletes is associated with transient impairment of left ventricular (LV) function, known as cardiac fatigue. Cardiac effects of prolonged exercise in horses remain unknown.Objectives :To investigate the effects of prolonged exercise on LV systolic and diastolic function in horses.Animals: Twenty-six horses competing in 120–160 km endurance rides.Methods: Cross-sectional field study. Echocardiography was performed before and after rides, and the following morning, and included two-dimensional echocardiography, anatomical M-mode, pulsed-wave tissue Doppler imaging, and two-dimensional speckle tracking. Correlation between echocardiographic variables and cardiac troponin I was evaluated.Results: Early diastolic myocardial velocities decreased significantly in longitudinal (baseline: −17.4 ± 2.4cm/s; end of ride: −15.8 ± 3.2cm/s (P = .013); morning after: −15.4 ± 3.0cm/s (P = .0033)) and radial directions (−32.8 ± 3.4cm/s; −28.1 ± 5.8cm/s (P < .001); −26.4 ± 5.5cm/s (P < .001)). Early diastolic strain rates decreased significantly in longitudinal (1.58 ± 0.27s−1; 1.45 ± 0.26s−1 (P = .036); 1.41 ± 0.25s−1 (P = .013)) and circumferential directions (2.43 ± 0.29s−1; 1.96 ± 0.46s−1 (P < .001); 2.11 ± 0.32s−1 (P < .001)). Systolic variables showed ambiguous results. No correlations with serum cardiac troponin I concentrations were evident.Conclusions and Clinical Importance: Prolonged exercise in horses is associated with impaired LV diastolic function. Reduced ventricular filling persisted for 7–21 hours despite normalization of biochemical indicators of hydration status, indicating that the observed changes were not entirely related to altered preload conditions. The clinical relevance of cardiac fatigue in horses remains uncertain.
AB - Background: Prolonged exercise in human athletes is associated with transient impairment of left ventricular (LV) function, known as cardiac fatigue. Cardiac effects of prolonged exercise in horses remain unknown.Objectives :To investigate the effects of prolonged exercise on LV systolic and diastolic function in horses.Animals: Twenty-six horses competing in 120–160 km endurance rides.Methods: Cross-sectional field study. Echocardiography was performed before and after rides, and the following morning, and included two-dimensional echocardiography, anatomical M-mode, pulsed-wave tissue Doppler imaging, and two-dimensional speckle tracking. Correlation between echocardiographic variables and cardiac troponin I was evaluated.Results: Early diastolic myocardial velocities decreased significantly in longitudinal (baseline: −17.4 ± 2.4cm/s; end of ride: −15.8 ± 3.2cm/s (P = .013); morning after: −15.4 ± 3.0cm/s (P = .0033)) and radial directions (−32.8 ± 3.4cm/s; −28.1 ± 5.8cm/s (P < .001); −26.4 ± 5.5cm/s (P < .001)). Early diastolic strain rates decreased significantly in longitudinal (1.58 ± 0.27s−1; 1.45 ± 0.26s−1 (P = .036); 1.41 ± 0.25s−1 (P = .013)) and circumferential directions (2.43 ± 0.29s−1; 1.96 ± 0.46s−1 (P < .001); 2.11 ± 0.32s−1 (P < .001)). Systolic variables showed ambiguous results. No correlations with serum cardiac troponin I concentrations were evident.Conclusions and Clinical Importance: Prolonged exercise in horses is associated with impaired LV diastolic function. Reduced ventricular filling persisted for 7–21 hours despite normalization of biochemical indicators of hydration status, indicating that the observed changes were not entirely related to altered preload conditions. The clinical relevance of cardiac fatigue in horses remains uncertain.
KW - Diastolic function
KW - Echocardiography
KW - Speckle tracking
KW - Tissue Doppler imaging
U2 - 10.1111/jvim.13982
DO - 10.1111/jvim.13982
M3 - Journal article
C2 - 27305095
VL - 30
SP - 1260
EP - 1269
JO - Journal of Veterinary Internal Medicine
JF - Journal of Veterinary Internal Medicine
SN - 0891-6640
IS - 4
ER -
ID: 165574268