Glukagonlignende peptid 1-receptoragonisten semaglutid

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Semaglutide is a glucagon-like peptide-1 receptor-agonist (GLP-1 RA), which is injected subcutaneously once a week for treatment of Type 2 diabetes. In this review, the present results of semaglutide treatment are presented. Semaglutide has been evaluated in more than 8,000 patients across the spectrum of Type 2 diabetes. Trials with semaglutide have demonstrated superiority with sustained improved glycaemic control and weight loss compared to oral antidiabetic agents, other GLP-1 RAs and basalinsulin. In addition, semaglutide significantly decreased the occurrence of cardiovascular events compared with standard pharmacological diabetic treatment combined with placebo.

Translated title of the contributionThe glucagon-like peptide-1 receptor-agonist semaglutide
Original languageDanish
Article numberV03190155
JournalUgeskrift for Laeger
Volume181
Number of pages5
ISSN0041-5782
Publication statusPublished - 2019

ID: 241276061