Gap junctions-guards of excitability

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Gap junctions-guards of excitability. / Stroemlund, Line Waring; Jensen, Christa Funch; Qvortrup, Klaus; Delmar, Mario; Nielsen, Morten Schak.

In: Biochemical Society Transactions, Vol. 43, No. 3, 01.06.2015, p. 508-12.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Stroemlund, LW, Jensen, CF, Qvortrup, K, Delmar, M & Nielsen, MS 2015, 'Gap junctions-guards of excitability', Biochemical Society Transactions, vol. 43, no. 3, pp. 508-12. https://doi.org/10.1042/BST20150059

APA

Stroemlund, L. W., Jensen, C. F., Qvortrup, K., Delmar, M., & Nielsen, M. S. (2015). Gap junctions-guards of excitability. Biochemical Society Transactions, 43(3), 508-12. https://doi.org/10.1042/BST20150059

Vancouver

Stroemlund LW, Jensen CF, Qvortrup K, Delmar M, Nielsen MS. Gap junctions-guards of excitability. Biochemical Society Transactions. 2015 Jun 1;43(3):508-12. https://doi.org/10.1042/BST20150059

Author

Stroemlund, Line Waring ; Jensen, Christa Funch ; Qvortrup, Klaus ; Delmar, Mario ; Nielsen, Morten Schak. / Gap junctions-guards of excitability. In: Biochemical Society Transactions. 2015 ; Vol. 43, No. 3. pp. 508-12.

Bibtex

@article{e99cbc85dac44cb893b6011637960db2,
title = "Gap junctions-guards of excitability",
abstract = "Cardiomyocytes are connected by mechanical and electrical junctions located at the intercalated discs (IDs). Although these structures have long been known, it is becoming increasingly clear that their components interact. This review describes the involvement of the ID in electrical disturbances of the heart and focuses on the role of the gap junctional protein connexin 43 (Cx43). Current evidence shows that Cx43 plays a crucial role in organizing microtubules at the intercalated disc and thereby regulating the trafficking of the cardiac sodium channel NaV1.5 to the membrane.",
author = "Stroemlund, {Line Waring} and Jensen, {Christa Funch} and Klaus Qvortrup and Mario Delmar and Nielsen, {Morten Schak}",
year = "2015",
month = jun,
day = "1",
doi = "10.1042/BST20150059",
language = "English",
volume = "43",
pages = "508--12",
journal = "Biochemical Society Transactions",
issn = "0300-5127",
publisher = "Portland Press Ltd.",
number = "3",

}

RIS

TY - JOUR

T1 - Gap junctions-guards of excitability

AU - Stroemlund, Line Waring

AU - Jensen, Christa Funch

AU - Qvortrup, Klaus

AU - Delmar, Mario

AU - Nielsen, Morten Schak

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Cardiomyocytes are connected by mechanical and electrical junctions located at the intercalated discs (IDs). Although these structures have long been known, it is becoming increasingly clear that their components interact. This review describes the involvement of the ID in electrical disturbances of the heart and focuses on the role of the gap junctional protein connexin 43 (Cx43). Current evidence shows that Cx43 plays a crucial role in organizing microtubules at the intercalated disc and thereby regulating the trafficking of the cardiac sodium channel NaV1.5 to the membrane.

AB - Cardiomyocytes are connected by mechanical and electrical junctions located at the intercalated discs (IDs). Although these structures have long been known, it is becoming increasingly clear that their components interact. This review describes the involvement of the ID in electrical disturbances of the heart and focuses on the role of the gap junctional protein connexin 43 (Cx43). Current evidence shows that Cx43 plays a crucial role in organizing microtubules at the intercalated disc and thereby regulating the trafficking of the cardiac sodium channel NaV1.5 to the membrane.

U2 - 10.1042/BST20150059

DO - 10.1042/BST20150059

M3 - Journal article

C2 - 26009199

VL - 43

SP - 508

EP - 512

JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

SN - 0300-5127

IS - 3

ER -

ID: 138184779