Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related Peptide-induced cerebral reactivity

Research output: Contribution to journalJournal articleResearchpeer-review

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Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related Peptide-induced cerebral reactivity. / Chadha, Preet S; Jepps, Thomas A; Carr, Georgina; Stott, Jennifer B; Zhu, Hei-Lei; Cole, William C; Greenwood, Iain A.

In: Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 34, No. 4, 04.2014, p. 887-93.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Chadha, PS, Jepps, TA, Carr, G, Stott, JB, Zhu, H-L, Cole, WC & Greenwood, IA 2014, 'Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related Peptide-induced cerebral reactivity', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 34, no. 4, pp. 887-93. https://doi.org/10.1161/ATVBAHA.114.303405

APA

Chadha, P. S., Jepps, T. A., Carr, G., Stott, J. B., Zhu, H-L., Cole, W. C., & Greenwood, I. A. (2014). Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related Peptide-induced cerebral reactivity. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(4), 887-93. https://doi.org/10.1161/ATVBAHA.114.303405

Vancouver

Chadha PS, Jepps TA, Carr G, Stott JB, Zhu H-L, Cole WC et al. Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related Peptide-induced cerebral reactivity. Arteriosclerosis, Thrombosis, and Vascular Biology. 2014 Apr;34(4):887-93. https://doi.org/10.1161/ATVBAHA.114.303405

Author

Chadha, Preet S ; Jepps, Thomas A ; Carr, Georgina ; Stott, Jennifer B ; Zhu, Hei-Lei ; Cole, William C ; Greenwood, Iain A. / Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related Peptide-induced cerebral reactivity. In: Arteriosclerosis, Thrombosis, and Vascular Biology. 2014 ; Vol. 34, No. 4. pp. 887-93.

Bibtex

@article{665f409578f5481b8ba5399f1259313e,
title = "Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related Peptide-induced cerebral reactivity",
abstract = "Middle cerebral artery (MCA) diameter is regulated by inherent myogenic activity and the effect of potent vasodilators such as calcitonin gene-related peptide (CGRP). Previous studies showed that MCAs express KCNQ1, 4, and 5 potassium channel genes, and the expression products (Kv7 channels) participate in the myogenic control of MCA diameter. The present study investigated the contribution of Kv7.4 and Kv7.5 isoforms to myogenic and CGRP regulation of MCA diameter and determined whether they were affected in hypertensive animals.",
author = "Chadha, {Preet S} and Jepps, {Thomas A} and Georgina Carr and Stott, {Jennifer B} and Hei-Lei Zhu and Cole, {William C} and Greenwood, {Iain A}",
year = "2014",
month = "4",
doi = "10.1161/ATVBAHA.114.303405",
language = "English",
volume = "34",
pages = "887--93",
journal = "Arteriosclerosis, Thrombosis, and Vascular Biology",
issn = "1079-5642",
publisher = "Lippincott Williams & Wilkins",
number = "4",

}

RIS

TY - JOUR

T1 - Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related Peptide-induced cerebral reactivity

AU - Chadha, Preet S

AU - Jepps, Thomas A

AU - Carr, Georgina

AU - Stott, Jennifer B

AU - Zhu, Hei-Lei

AU - Cole, William C

AU - Greenwood, Iain A

PY - 2014/4

Y1 - 2014/4

N2 - Middle cerebral artery (MCA) diameter is regulated by inherent myogenic activity and the effect of potent vasodilators such as calcitonin gene-related peptide (CGRP). Previous studies showed that MCAs express KCNQ1, 4, and 5 potassium channel genes, and the expression products (Kv7 channels) participate in the myogenic control of MCA diameter. The present study investigated the contribution of Kv7.4 and Kv7.5 isoforms to myogenic and CGRP regulation of MCA diameter and determined whether they were affected in hypertensive animals.

AB - Middle cerebral artery (MCA) diameter is regulated by inherent myogenic activity and the effect of potent vasodilators such as calcitonin gene-related peptide (CGRP). Previous studies showed that MCAs express KCNQ1, 4, and 5 potassium channel genes, and the expression products (Kv7 channels) participate in the myogenic control of MCA diameter. The present study investigated the contribution of Kv7.4 and Kv7.5 isoforms to myogenic and CGRP regulation of MCA diameter and determined whether they were affected in hypertensive animals.

U2 - 10.1161/ATVBAHA.114.303405

DO - 10.1161/ATVBAHA.114.303405

M3 - Journal article

C2 - 24558103

VL - 34

SP - 887

EP - 893

JO - Arteriosclerosis, Thrombosis, and Vascular Biology

JF - Arteriosclerosis, Thrombosis, and Vascular Biology

SN - 1079-5642

IS - 4

ER -

ID: 104942948