Clinical PET of neuroendocrine tumors using 64Cu-DOTATATE: first-in-humans study
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Clinical PET of neuroendocrine tumors using 64Cu-DOTATATE : first-in-humans study. / Pfeifer, Andreas Klaus; Knigge, Ulrich; Mortensen, Jann; Oturai, Peter; Berthelsen, Anne Kiil; Loft, Annika; Binderup, Tina; Rasmussen, Palle; Elema, Dennis Ringkjøbing; Klausen, Thomas Levin; Holm, Søren; von Benzon, Eric; Højgaard, Liselotte; Kjaer, Andreas.
In: Journal of Nuclear Medicine, Vol. 53, No. 8, 08.2012, p. 1207-15.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Clinical PET of neuroendocrine tumors using 64Cu-DOTATATE
T2 - first-in-humans study
AU - Pfeifer, Andreas Klaus
AU - Knigge, Ulrich
AU - Mortensen, Jann
AU - Oturai, Peter
AU - Berthelsen, Anne Kiil
AU - Loft, Annika
AU - Binderup, Tina
AU - Rasmussen, Palle
AU - Elema, Dennis Ringkjøbing
AU - Klausen, Thomas Levin
AU - Holm, Søren
AU - von Benzon, Eric
AU - Højgaard, Liselotte
AU - Kjaer, Andreas
PY - 2012/8
Y1 - 2012/8
N2 - The use of positron emitter-labeled compounds for somatostatin receptor imaging (SRI) has become attractive because of the prospect of improved spatial resolution, accelerated imaging procedures, and the ability to quantify tissue radioactivity concentrations. This paper provides results from first-in-humans use of (64)Cu-DOTATATE, an avidly binding somatostatin receptor ligand linked to a radioisotope with intermediate half-life and favorable positron energy (half-life, 12.7 h; maximum positron energy, 0.653 MeV).
AB - The use of positron emitter-labeled compounds for somatostatin receptor imaging (SRI) has become attractive because of the prospect of improved spatial resolution, accelerated imaging procedures, and the ability to quantify tissue radioactivity concentrations. This paper provides results from first-in-humans use of (64)Cu-DOTATATE, an avidly binding somatostatin receptor ligand linked to a radioisotope with intermediate half-life and favorable positron energy (half-life, 12.7 h; maximum positron energy, 0.653 MeV).
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Neuroendocrine Tumors
KW - Octreotide
KW - Organometallic Compounds
KW - Positron-Emission Tomography
KW - Quality Control
KW - Radiation Dosage
KW - Radiochemistry
KW - Tomography, Emission-Computed, Single-Photon
U2 - 10.2967/jnumed.111.101469
DO - 10.2967/jnumed.111.101469
M3 - Journal article
C2 - 22782315
VL - 53
SP - 1207
EP - 1215
JO - The Journal of Nuclear Medicine
JF - The Journal of Nuclear Medicine
SN - 0161-5505
IS - 8
ER -
ID: 45863450