A global map of hemispheric influenza vaccine recommendations based on local patterns of viral circulation
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A global map of hemispheric influenza vaccine recommendations based on local patterns of viral circulation. / Alonso, Wladimir J.; Yu, Christine; Viboud, Cecile; Richard, Stephanie A.; Schuck-paim, Cynthia; Simonsen, Lone; Mello, Wyller A.; Miller, Mark A.
In: Scientific Reports, Vol. 5, 17214, 01.12.2015, p. 1-6.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - A global map of hemispheric influenza vaccine recommendations based on local patterns of viral circulation
AU - Alonso, Wladimir J.
AU - Yu, Christine
AU - Viboud, Cecile
AU - Richard, Stephanie A.
AU - Schuck-paim, Cynthia
AU - Simonsen, Lone
AU - Mello, Wyller A.
AU - Miller, Mark A.
PY - 2015/12/1
Y1 - 2015/12/1
N2 - Both the Northern and the Southern Hemisphere annual WHO influenza vaccine recommendations are designed to ensure vaccine delivery before the winter-time peak of viral circulation in each hemisphere. However, influenza seasonal patterns are highly diverse in tropical countries and may be out of phase with the WHO recommendations for their respective hemisphere. We modelled the peak timing of influenza activity for 125 countries using laboratory-based surveillance data from the WHO’s FLUNET database and compared it with the influenza hemispheric recommendations in place. Influenza vaccine recommendations for respectively 25% and 39% of the Northern and Southern Hemisphere countries were out of phase with peak influenza circulation in their corresponding hemisphere (62% and 53%, respectively, when the analysis was limited to the 52 countries in the tropical belt). These results indicate that routine influenza immunization efforts should be closely tailored to local patterns of viral circulation, rather than a country’s hemispheric position.
AB - Both the Northern and the Southern Hemisphere annual WHO influenza vaccine recommendations are designed to ensure vaccine delivery before the winter-time peak of viral circulation in each hemisphere. However, influenza seasonal patterns are highly diverse in tropical countries and may be out of phase with the WHO recommendations for their respective hemisphere. We modelled the peak timing of influenza activity for 125 countries using laboratory-based surveillance data from the WHO’s FLUNET database and compared it with the influenza hemispheric recommendations in place. Influenza vaccine recommendations for respectively 25% and 39% of the Northern and Southern Hemisphere countries were out of phase with peak influenza circulation in their corresponding hemisphere (62% and 53%, respectively, when the analysis was limited to the 52 countries in the tropical belt). These results indicate that routine influenza immunization efforts should be closely tailored to local patterns of viral circulation, rather than a country’s hemispheric position.
U2 - 10.1038/srep17214
DO - 10.1038/srep17214
M3 - Journal article
VL - 5
SP - 1
EP - 6
JO - Scientific Reports
JF - Scientific Reports
SN - 2045-2322
M1 - 17214
ER -
ID: 173807851