Thomas Andrew Qvistgaard Jepps

Thomas Andrew Qvistgaard Jepps

Associate Professor

ORCID: 0000-0002-9903-714X

Publication year:
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1 - 49 out of 49Page size: 50
  1. 2024
  2. Published

    Mesenteric artery smooth muscle cells from hypertensive rats have increased microtubule acetylation

    Mozzicato, Anthony Michael, Bastrup, Joakim Armstrong, Sanchez-Alonso, J. L., van der Horst, Jennifer, Gorelik, J., Hägglund, Per Mårten & Jepps, Thomas Andrew Qvistgaard, 2024, In: The Biochemical journal. 481, 5, p. 387-403

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    Acute, pro-contractile effects of prorenin on rat mesenteric arteries

    Rognant, Salomé, Baldwin, S. N., Pritchard, H. A. T., Greenstein, A., Callø, Kirstine, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2023, In: FASEB Journal. 37, 12, 18 p., e23282.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Colchicine enhances β adrenoceptor-mediated vasodilation in men with essential hypertension

    Ehlers, T. S., van der Horst, Jennifer, Møller, S., Piil, P. K., Gliemann, Lasse, Aalkjær, Christian, Jepps, Thomas Andrew Qvistgaard & Hellsten, Ylva, 2023, In: British Journal of Clinical Pharmacology. 89, 7, p. 2179-2189 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Cycling matters: Sex hormone regulation of vascular potassium channels

    Baldwin, S. N., Jepps, Thomas Andrew Qvistgaard & Greenwood, I. A., 2023, In: Channels. 17, 1, 19 p., 2217637.

    Research output: Contribution to journal › Review › Research › peer-review

  7. Published

    Medicinal plant rosemary relaxes blood vessels by activating vascular smooth muscle KCNQ channels

    Manville, R. W., Baldwin, S. N., Eriksen, E. Ø., Jepps, Thomas Andrew Qvistgaard & Abbott, G. W., 2023, In: FASEB Journal. 37, 9, p. 1-15 e23125.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Proteomic mapping reveals dysregulated angiogenesis in the cerebral arteries of rats with early-onset hypertension

    Bastrup, Joakim Armstrong & Jepps, Thomas Andrew Qvistgaard, 2023, In: Journal of Biological Chemistry. 299, 10, p. 1-16 105221.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Vascular smooth muscle-specific YAP/TAZ deletion triggers aneurysm development in mouse aorta

    Arévalo Martínez, M., Ritsvall, O., Bastrup, Joakim Armstrong, Celik, S., Jakobsson, G., Daoud, F., Winqvist, C., Aspberg, A., Rippe, C., Maegdefessel, L., Schiopu, A., Jepps, Thomas Andrew Qvistgaard, Holmberg, J., Swärd, K. & Albinsson, S., 2023, In: JCI insight. 8, 17, 25 p., e170845.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2022
  11. Published

    Dynein coordinates β2-adrenoceptor-mediated relaxation in normotensive and hypertensive rat mesenteric arteries

    van der Horst, Jennifer, Rognant, Salomé, Hellsten, Ylva, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2022, In: Hypertension. 79, 10, p. 2214-2227 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Identification of novel proteins and mechanistic pathways associated with early-onset hypertension by deep proteomic mapping of resistance arteries

    Bastrup, Joakim Armstrong, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2022, In: Journal of Biological Chemistry. 298, 1, 17 p., 101512.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    KCNQ5 activation by tannins mediates vasorelaxant effects of barks used in Native American botanical medicine

    Manville, R. W., Redford, K. E., van der Horst, Jennifer, Hogenkamp, D. J., Jepps, Thomas Andrew Qvistgaard & Abbott, G. W., 2022, In: FASEB Journal. 36, 9, 15 p., e22457.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The impact of an atrial septal defect on the progression of atrial tachypacing-induced atrial fibrillation in a Danish Landrace pig: A case report

    Saljic, Arnela, Hertel, Julie Norup, Leonhardt, C., Nissen, Sarah Dalgas, Dobrev, D., Jepps, Thomas Andrew Qvistgaard, Jespersen, Thomas & Sattler, Stefan M, 2022, In: IJC Heart and Vasculature. 40, 3 p., 101054.

    Research output: Contribution to journal › Letter › Research › peer-review

  15. Published

    The microtubule network enables Src kinase interaction with the Na,K-ATPase to generate Ca2+ flashes in smooth muscle cells

    Rognant, Salomé, Kravtsova, V. V., Bouzinova, E. V., Melnikova, E. V., Krivoi, I. I., Pierre, S. V., Aalkjær, Christian, Jepps, Thomas Andrew Qvistgaard & Matchkov, V. V., 2022, In: Frontiers in Physiology. 13, 14 p., 1007340.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2021
  17. Published

    Dynein regulates Kv7.4 channel trafficking from the cell membrane

    van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Editorial: Kv7 Channels: Structure, Physiology, and Pharmacology

    Jepps, Thomas Andrew Qvistgaard, Barrese, V. & Miceli, F., 2021, In: Frontiers in Physiology. 12, 4 p., 679317.

    Research output: Contribution to journal › Editorial › Research › peer-review

  19. Published

    Functional sympatholysis in mouse skeletal muscle involves sarcoplasmic reticulum swelling in arterial smooth muscle cells

    van der Horst, Jennifer, Møller, S., Kjeldsen, Sasha Alexandra Sampson, Wojtaszewski, Jørgen F P, Hellsten, Ylva & Jepps, Thomas Andrew Qvistgaard, 2021, In: Physiological Reports. 9, 23, 10 p., e15133.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    KCNQ5 Potassium Channel Activation Underlies Vasodilation by Tea

    Redford, K. E., Rognant, Salomé, Jepps, Thomas Andrew Qvistgaard & Abbott, G. W., 2021, In: Cellular Physiology and Biochemistry. 55, S3, p. 46-64 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Kv7 channel trafficking by the microtubule network in vascular smooth muscle

    Jepps, Thomas Andrew Qvistgaard, 2021, In: Acta Physiologica. 232, 3, 12 p., e13692.

    Research output: Contribution to journal › Review › Research › peer-review

  22. 2020
  23. Published

    Acetaminophen (Paracetamol) Metabolites Induce Vasodilation and Hypotension by Activating Kv7 Potassium Channels Directly and Indirectly

    van der Horst, Jennifer, Manville, R. W., Hayes, K., Thomsen, M. B., Abbott, G. W. & Jepps, Thomas Andrew Qvistgaard, 2020, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 40, 5, p. 1207-1219 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Cyclic AMP-Dependent Regulation of Kv7 Voltage-Gated Potassium Channels

    van der Horst, Jennifer, Greenwood, I. A. & Jepps, Thomas Andrew Qvistgaard, 2020, In: Frontiers in Physiology. 11, 12 p., 727.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings

    Zacharias, T., Flouda, K., Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael J., 2020, In: Biochemical Pharmacology. 173, 14 p., 113631.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Genome-wide association study identifies locus at chromosome 2q32.1 associated with syncope and collapse

    lvs502, lvs502, Andreasen, Laura Korsholm, Hagen, C. M., Ahlberg, G., Ghouse, Jonas, Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Hedley, P., Haunsø, Stig, Svendsen, Jesper Hastrup, Kanters, Jørgen K., Jepps, Thomas Andrew Qvistgaard, Skov, M. W., Christiansen, M. & Olesen, Morten Steen Salling, 2020, In: Cardiovascular Research. 116, 1, p. 138-148

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2019
  28. Published

    TMEM16A is implicated in the regulation of coronary flow and is altered in hypertension

    Askew Page, H. R., Dalsgaard, T., Baldwin, S. N., Jepps, Thomas Andrew Qvistgaard, Povstyan, O., Olesen, Søren-Peter & Greenwood, I. A., Jun 2019, In: British Journal of Pharmacology. 176, 11, p. 1635-1648

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Kcne4 deletion sex dependently inhibits the RISK pathway response and exacerbates hepatic ischemia-reperfusion injury in mice

    Hu, Z., Jepps, Thomas Andrew Qvistgaard, Zhou, L., Liu, J., Li, M. & Abbott, G. W., 1 May 2019, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 316, 5, p. R552-R562

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Deletion in mice of X-linked, Brugada syndrome- and atrial fibrillation-associated Kcne5 augments ventricular KV currents and predisposes to ventricular arrhythmia

    David, J., Lisewski, U., Crump, S. M., Jepps, Thomas Andrew Qvistgaard, Bocksteins, E., Wilck, N., Lossie, J., Roepke, T. K., Schmitt, Nicole & Abbott, G. W., Feb 2019, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 2, p. 2537-2552 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Discovery of the first genome-wide significant risk loci for syncope and collapse: [Meeting Abstract]

    Ahlberg, G., lvs502, lvs502, Andreasen, L., Hagen, C. M., Ghouse, Jonas, Baekvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Hedley, P., Haunsø, Stig, Svendsen, Jesper Hastrup, Jepps, Thomas Andrew Qvistgaard, Skov, M. W., Christiansen, M. & Olesen, Morten Steen Salling, 2019, In: European Heart Journal. 40, S1, p. 2539-2539 4259 .

    Research output: Contribution to journal › Conference abstract in journal › Research

  32. Published

    KCNQ5 activation is a unifying molecular mechanism shared by genetically and culturally diverse botanical hypotensive folk medicines

    Manville, R. W., van der Horst, Jennifer, Redford, K. E., Katz, B. B., Jepps, Thomas Andrew Qvistgaard & Abbott, G. W., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 42, p. 21236-21245

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2018
  34. Published

    Impaired Kv7 channel function in cerebral arteries of a tauopathy mouse model (rTg4510)

    de Jong, I. E. M. & Jepps, Thomas Andrew Qvistgaard, Dec 2018, In: Physiological Reports. 6, 23, 10 p., e13920 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Contractile responses in intact and mucosa-denuded human ureter: a comparison with urinary bladder detrusor preparations

    Roedel, M., Ravens, U., Kasper, M., Wirth, M. P., Jepps, Thomas Andrew Qvistgaard & Propping, S., 1 Aug 2018, In: Naunyn-Schmiedeberg's Archives of Pharmacology. 391, 8, p. 773-782 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Angiotensin II Promotes KV7.4 Channels Degradation Through Reduced Interaction With HSP90 (Heat Shock Protein 90)

    Barrese, V., Stott, J. B., Figueiredo, H. B., Aubdool, A. A., Hobbs, A. J., Jepps, Thomas Andrew Qvistgaard, McNeish, A. J. & Greenwood, I. A., Jun 2018, In: Hypertension. 71, 6, p. 1091-1100 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries

    Khammy, M. M., Kim, S., Bentzen, Bo Hjorth, Lee, S., Choi, I., Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: British Journal of Pharmacology. 175, 3, p. 501-516 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Microtubule Regulation of Kv7 Channels Orchestrates cAMP-Mediated Vasorelaxations in Rat Arterial Smooth Muscle

    Lindman, J., Khammy, M. M., Lundegaard, Pia Rengtved, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: Hypertension. 71, 2, p. 336-345 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2017
  40. Published

    Unravelling the complexities of vascular smooth muscle ion channels: Fine tuning of activity by ancillary subunits

    Jepps, Thomas Andrew Qvistgaard, Oct 2017, In: Pharmacology & Therapeutics. 178, p. 57-66 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  41. 2016
  42. Published

    Kcne4 Deletion Sex-Dependently Alters Vascular Reactivity

    Abbott, G. W. & Jepps, Thomas Andrew Qvistgaard, 7 Oct 2016, In: Journal of Vascular Research. 53, 3-4, p. 138-148 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension

    Carr, G., Barrese, V., Stott, J. B., Povstyan, O. V., Jepps, Thomas Andrew Qvistgaard, Figueiredo, H. B., Zheng, D., Jamshidi, Y. & Greenwood, I. A., 7 Jul 2016, In: Cardiovascular Research. 112, p. 581-589 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Molecular and functional characterization of Kv 7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats

    Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter, Greenwood, I. A. & Dalsgaard, T., May 2016, In: British Journal of Pharmacology. 173, 9, p. 1478-1490 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts

    Skarsfeldt, M. A., Jepps, Thomas Andrew Qvistgaard, Bomholtz, Sofia Hammami, Abildgaard, L., Sørensen, U. S., Gregers, E., Svendsen, Jesper Hastrup, Diness, J. G., Grunnet, M., Schmitt, Nicole, Olesen, Søren-Peter & Bentzen, Bo Hjorth, Apr 2016, In: Pfluegers Archiv. 468, 4, p. 643-654 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. 2015
  47. Published

    Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone

    Jepps, Thomas Andrew Qvistgaard, Carr, G., Lundegaard, Pia Rengtved, Olesen, Søren-Peter & Greenwood, I. A., 15 Dec 2015, In: Journal of Physiology. 593, 24, p. 5325-40 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats

    Stott, J. B., Barrese, V., Jepps, Thomas Andrew Qvistgaard, Leighton, E. V. & Greenwood, I. A., Mar 2015, In: Hypertension. 65, 3, p. 676-82 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. 2014
  50. Published

    KV7 potassium channels: a new therapeutic target in smooth muscle disorders

    Stott, J. B., Jepps, Thomas Andrew Qvistgaard & Greenwood, I. A., 12 Dec 2014, In: Drug Discovery Today. 19, 4, p. 413-424 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Vasorelaxant effects of novel Kv7.4 channel enhancers ML213 and NS15370

    Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Stott, J. B., Povstyan, O. V., Sivaloganathan, K., Dalby-Brown, W. & Greenwood, I. A., 9 Jun 2014, In: British Journal of Pharmacology. 171, 19, p. 4413-4424 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related Peptide-induced cerebral reactivity

    Chadha, P. S., Jepps, Thomas Andrew Qvistgaard, Carr, G., Stott, J. B., Zhu, H., Cole, W. C. & Greenwood, I. A., Apr 2014, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 34, 4, p. 887-93 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. 2013
  54. Published

    Contribution of KV7 Channels to Basal Coronary Flow and Active Response to Ischemia

    Khanamiri, S., Soltysinska, E., Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Chadha, P. S., Schmitt, Nicole, Greenwood, I. A. & Olesen, Søren-Peter, 30 Sep 2013, In: Hypertension. 62, 6, p. 1090-1097 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    One man's side effect is another man's therapeutic opportunity: targeting Kv7 channels in smooth muscle disorders

    Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter & Greenwood, I. A., 2013, In: British Journal of Pharmacology. 168, 1, p. 19-27 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. 2012
  57. Published

    Pharmacological dissection of K(v)7.1 channels in systemic and pulmonary arteries

    Chadha, P. S., Zunke, F., Davis, A. J., Jepps, Thomas Andrew Qvistgaard, Linders, J. T. M., Schwake, M., Towart, R. & Greenwood, I. A., Jun 2012, In: British Journal of Pharmacology. 166, 4, p. 1377-87 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Reduced KCNQ4-encoded voltage-dependent potassium channel activity underlies impaired ß-adrenoceptor-mediated relaxation of renal arteries in hypertension

    Chadha, P. S., Zunke, F., Zhu, H., Davis, A. J., Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter, Cole, W. C., Moffatt, J. D. & Greenwood, I., 2012, In: Hypertension. 59, 4, p. 877-84 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. 2011
  60. Published

    Downregulation of Kv7.4 channel activity in primary and secondary hypertension

    Jepps, Thomas Andrew Qvistgaard, Chadha, P. S., Davis, A. J., Harhun, M. I., Cockerill, G. W., Olesen, S. P., Hansen, R. S. & Greenwood, I. A., 2 Aug 2011, In: Circulation. 124, 5, p. 602-11 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Expression and function of the K+ channel KCNQ genes in human arteries

    Ng, F. L., Davis, A. J., Jepps, Thomas Andrew Qvistgaard, Harhun, M. I., Yeung, S. Y., Wan, A., Reddy, M., Melville, D., Nardi, A., Khong, T. K. & Greenwood, I. A., Jan 2011, In: British Journal of Pharmacology. 162, 1, p. 42-53 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. 2010
  63. Published

    Expression profile and protein translation of TMEM16A in murine smooth muscle

    Davis, A. J., Forrest, A. S., Jepps, Thomas Andrew Qvistgaard, Valencik, M. L., Wiwchar, M., Singer, C. A., Sones, W. R., Greenwood, I. A. & Leblanc, N., Nov 2010, In: A J P: Cell Physiology (Online). 299, 5, p. C948-59

    Research output: Contribution to journal › Journal article › Research

  64. 2009
  65. Published

    Molecular and functional characterization of Kv7 K+ channel in murine gastrointestinal smooth muscles

    Jepps, Thomas Andrew Qvistgaard, Greenwood, I. A., Moffatt, J. D., Sanders, K. M. & Ohya, S., Jul 2009, In: A J P: Gastrointestinal and Liver Physiology (Online). 297, 1, p. G107-15

    Research output: Contribution to journal › Journal article › Research

ID: 51475012