Sofia Hammami Bomholtz

Sofia Hammami Bomholtz

Postdoc


  1. 2022
  2. Published

    Whole-Exome Sequencing Implicates Neuronal Calcium Channel with Familial Atrial Fibrillation

    Vad, Oliver Tim Bundgaard, Yan, Y., Denti, F., Ahlberg, Gustav, Refsgaard, L., Bomholtz, Sofia Hammami, Santos, J. L., Rasmussen, Simon, Haunsø, Stig, Svendsen, Jesper Hastrup, Christophersen, I. E., Schmitt, Nicole, Olesen, Morten Steen Salling & Bentzen, Bo Hjorth, 2022, In: Frontiers in Genetics. 13, 8 p., 806429.

    Research output: Contribution to journalJournal articlepeer-review

  3. 2020
  4. Published

    Functional phenotype variations of two novel Kv 7.1 mutations identified in patients with Long QT syndrome

    Bomholtz, Sofia Hammami, Refaat, M., Steffensen, Annette Buur, David, J., Espinosa, K., Nussbaum, R., Wojciak, J., Bentzen, Bo Hjorth, Scheinman, M. & Schmitt, Nicole, 2020, In: Pacing and Clinical Electrophysiology. 43, 2, p. 210-216 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Inhibition of KCa2 Channels Decreased the Risk of Ventricular Arrhythmia in the Guinea Pig Heart During Induced Hypokalemia

    Diness, J. G., Abildgaard, L., Bomholtz, Sofia Hammami, Skarsfeldt, M. A., Edvardsson, N., Sørensen, U. S., Grunnet, M. & Bentzen, B. H., 2020, In: Frontiers in Pharmacology. 11, 10 p., 749.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man

    Bentzen, Bo Hjorth, Bomholtz, Sofia Hammami, Simó-Vicens, R., Folkersen, L., Abildgaard, L., Speerschneider, T., Muthukumarasamy, K. M., Edvardsson, N., Sørensen, U. S., Grunnet, M. & Diness, J. G., 2020, In: Frontiers in Pharmacology. 11, 610.

    Research output: Contribution to journalJournal articlepeer-review

  7. 2019
  8. Published

    The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

    Kirchhoff, J. E., Skarsfeldt, M., Muthukumarasamy, K. M., Simó-Vicens, R., Bomholtz, Sofia Hammami, Abildgaard, L., Jespersen, Thomas, Sørensen, U. S., Grunnet, Morten, Bentzen, Bo Hjorth & Diness, Jonas Goldin, 2019, In: Frontiers in Pharmacology. 10, 13 p., 668.

    Research output: Contribution to journalJournal articlepeer-review

  9. 2018
  10. Published

    2,6-Bis(2-Benzimidazolyl)Pyridine (BBP) Is a Potent and Selective Inhibitor of Small Conductance Calcium-Activated Potassium (SK) Channels

    Simó-Vicens, R., Bomholtz, Sofia Hammami, Sørensen, U. S. & Bentzen, Bo Hjorth, 3 Dec 2018, In: Frontiers in Pharmacology. 9, 1409.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Atrium-specific ion channels in the zebrafish: A role of Iin atrial repolarization

    Skarsfeldt, M. A., Bomholtz, Sofia Hammami, Lundegaard, Pia Rengtved, Lopez-Izquierdo, A., Tristani-Firouzi, M. & Bentzen, Bo Hjorth, Jul 2018, In: Acta Physiologica (Print). 223, 3, 17 p., e13049.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    PKD Phosphorylation as Novel Pathway of KV11.1 Regulation

    Steffensen, Annette Buur, Bomholtz, Sofia Hammami, Andersen, M. N., Olsen, Jesper Velgaard, Mutsaers, N., Lundegaard, Pia Rengtved, Lundby, Alicia & Schmitt, Nicole, 2018, In: Cellular Physiology and Biochemistry. 47, 4, p. 1742-1750 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Profiling of GABAA and GABAB receptor expression in the myometrium of the human uterus

    Söderhielm, P. C., Klein, A. B., Bomholtz, Sofia Hammami & Jensen, Anders A., 2018, In: Life Sciences. 214, p. 145-152

    Research output: Contribution to journalJournal articlepeer-review

  14. 2017
  15. Published

    Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

    Diness, Jonas Goldin, Skibsbye, L., Simó-Vicens, R., Louro Larupa dos Santos, J., Lundegaard, Pia Rengtved, Citerni, C., Sauter, D. R. P., Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, U. S., Jespersen, Thomas, Grunnet, Morten & Bentzen, Bo Hjorth, 10 Oct 2017, In: Circulation: Arrhythmia and Electrophysiology. 10, 19 p., e005125.

    Research output: Contribution to journalJournal articlepeer-review

  16. 2016
  17. Published

    pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts

    Skarsfeldt, M. A., Jepps, Thomas Andrew Qvistgaard, Bomholtz, Sofia Hammami, Abildgaard, L., Sørensen, U. S., Gregers, E., Svendsen, Jesper Hastrup, Diness, J. G., Grunnet, M., Schmitt, Nicole, Olesen, Søren-Peter & Bentzen, Bo Hjorth, Apr 2016, In: Pfluegers Archiv. 468, 4, p. 643-654 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  18. 2015
  19. Published

    Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium

    Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, Sofia Hammami, Nielsen, Morten Schak, Grunnet, Morten, Bentzen, Bo Hjorth & Jespersen, Thomas, Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. 2014
  21. Published

    Cell volume changes regulate Slick (Slo2.1), but not Slack (Slo2.2) K+ channels

    Tejada, M. D. L. A., Stople, K., Bomholtz, Sofia Hammami, Meinild, A., Poulsen, A. N. & Klærke, Dan Arne, 2014, In: P L o S One. 9, 10, p. 1-8 8 p., e110833.

    Research output: Contribution to journalJournal articlepeer-review

  22. 2013
  23. Published

    A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein

    Andersen, M. N., Krzystanek, K., Petersen, F., Bomholtz, Sofia Hammami, Olesen, Søren-Peter, Abriel, H., Jespersen, Thomas & Rasmussen, Hanne Borger, 8 Nov 2013, In: The Journal of Biological Chemistry. 288, 52, p. 36841-54 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Purinergic signalling - a possible mechanism for KCNQ1 channel response to cell volume challenges

    Bomholtz, Sofia Hammami, Willumsen, N. J., Meinild, A., Klærke, Dan Arne & Novak, Ivana, 2013, In: Acta Physiologica (Print). 207, 3, p. 503-515 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. 2012
  26. Evidence for a common pharmacological interaction site on K(Ca)2 channels providing both selective activation and selective inhibition of the human K(Ca)2.1 subtype

    Hougaard, C., Bomholtz, Sofia Hammami, Eriksen, B. L., Sørensen, U. S., Jensen, Marianne Lund, Strøbæk, D., Christophersen, P. & Bomholtz, Sofia Hammami, Feb 2012, In: Molecular Pharmacology. 81, 2, p. 210-9 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. 2011
  28. Submitted

    Upregulation of KCNQ1 currents by the KCNE1 beta subunit is not caused by insertion of KCNQ1 into the membrane

    Bomholtz, Sofia Hammami, Willumsen, N. & Klærke, Dan Arne, 2011, (Submitted). 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  29. 2010
  30. Published

    KCNE1-induced increase in KCNQ1 currents is not mediated through enhanced membrane expression

    Bomholtz, Sofia Hammami, Willumsen, N. J. & Klærke, Dan Arne, Apr 2010, In: The FASEB Journal. 24, 610.6

    Research output: Contribution to journalConference abstract in journal

  31. Published

    KCNQ1 channel response to cell volume changes is not mediated by ATP release

    Bomholtz, Sofia Hammami, Willumsen, N., Novak, Ivana & Klærke, Dan Arne, 2010, In: Acta Physiologica Scandinavica. Supplementum. 198, Suppl 677, p. 213 1 p.

    Research output: Contribution to journalConference abstract in journal

  32. Published

    Mechanism for strict regulation of certain K+ channels by small, fast changes in cell volume

    Tejada, M. D. L. A., Stolpe, K., Bomholtz, Sofia Hammami, Willumsen, N. J., Poulsen, A. N. & Klærke, Dan Arne, 2010, In: Biophysical Journal. Supp. 1, p. 534a

    Research output: Contribution to journalConference abstract in journal

  33. Published

    Mechanisms underlying KCNQ1channel cell volume sensitivity

    Bomholtz, Sofia Hammami, 2010, Biologisk Institut: Museum Tusculanum. 112 p.

    Research output: Book/ReportPh.D. thesis

  34. 2009
  35. Published

    Cell volume and membrane stretch independently control K+ channel activity

    Bomholtz, Sofia Hammami, Willumsen, N. J., Olsen, H. L., Morera, F. J., Latorre, R. & Klærke, Dan Arne, 2009, In: Journal of Physiology. 587, Pt 10, p. 2225-31 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    Interaction of purinergic receptors, K+ channels and aquaporins in cell volume regulation

    Bomholtz, Sofia Hammami, Novak, Ivana, Willumsen, N. J. & Klærke, Dan Arne, 2009, In: Journal of Physiological Sciences. 1, p. 387 1 p.

    Research output: Contribution to journalConference abstract in journal

  37. 2007
  38. Published

    Cell volume and membrane stretch independently control K+ channel activity

    Bomholtz, Sofia Hammami, Willumsen, N. J. & Klærke, Dan Arne, 2007, In: The FASEB Journal. 5, p. A539-A539 1 p.

    Research output: Contribution to journalConference abstract in journal

ID: 40446292