Signe Sørensen Torekov

Signe Sørensen Torekov

Professor


  1. 2024
  2. E-pub ahead of print

    Endocannabinoid-related molecules predict the metabolic efficacy of GLP-1 receptor agonism in humans with obesity

    Matias, I., Lehmann, E. W., Zizzari, P., Byberg, Sarah, Cota, D., Torekov, Signe Sørensen & Quarta, C., 2024, (E-pub ahead of print) In: Journal of Endocrinological Investigation. 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published
  4. E-pub ahead of print
  5. 2023
  6. Published
  7. Published

    Combination of exercise and GLP-1 receptor agonist treatment reduces severity of metabolic syndrome, abdominal obesity, and inflammation: a randomized controlled trial

    Sandsdal, Rasmus Michael, Juhl, C. R., Jensen, Simon Birk Kjær, Lundgren, J. R., Janus, C., Blond, Martin Bæk, Rosenkilde, M., Bogh, A. F., Gliemann, Lasse, Jensen, Jens-Erik Beck, Antoniades, C., Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Cardiovascular Diabetology. 22, 1, 12 p., 41.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published
  9. Published
  10. Published

    Insufficient sleep predicts poor weight loss maintenance after one year

    Bogh, A. F., Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Sandsdal, Rasmus Michael, Lundgren, J. R., Noer, M. H., Vu, N. Q., Fiorenza, Matteo, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Sleep. 46, 5, 12 p., zsac295.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Neprilysin activity is increased in metabolic dysfunction-associated steatotic liver disease and normalizes after bariatric surgery or GLP-1 therapy

    Kjeldsen, S. A. S., Gluud, L. L., Werge, M. P., Pedersen, J. S., Bendtsen, F., Alexiadou, K., Tan, T., Torekov, S. S., Iepsen, E. W., Jensen, N. J., Richter, M. M., Goetze, J. P., Rungby, J., Hartmann, B., Holst, J. J., Holst, B., Holt, J., Gustafsson, F., Madsbad, S., Svane, M. S. & 2 others, Bojsen-Møller, K. N. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: iScience. 26, 11, 13 p., 108190.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published
  13. Published

    Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function

    Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Lundgren, J. R., Martinussen, C., Wiingaard, C., Knudsen, C., Frikke-Schmidt, Ruth, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Obesity. 31, 4, p. 977-989 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. 2022
  15. Published

    Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial

    Andersen, E., Juhl, C. R., Kjøller, E. T., Lundgren, J. R., Janus, C., Dehestani, Y., Saupstad, M., Ingerslev, L. R., Duun, O. M., Jensen, Simon Birk Kjær, Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten, Torekov, Signe Sørensen & Barrès, Romain, May 2022, In: Human Reproduction. 37, 7, p. 1414–1422 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published
  17. Published

    Effects of vegan diets on cardiometabolic health: A systematic review and meta-analysis of randomized controlled trials

    Termannsen, A. D., Clemmensen, K. K. B., Thomsen, J. M., Nørgaard, O., Díaz, L. J., Torekov, Signe Sørensen, Quist, Jonas Salling & Færch, K., 2022, In: Obesity Reviews. 23, 9, p. 1-17 e13462.

    Research output: Contribution to journalReviewpeer-review

  18. Published

    Exploratory analysis of eating- and physical activity-related outcomes from a randomized controlled trial for weight loss maintenance with exercise and liraglutide single or combination treatment

    Jensen, Simon Birk Kjær, Janus, C., Lundgren, J. R., Juhl, C. R., Sandsdal, Rasmus Michael, Olsen, L. M., Andresen, A., Borg, S. A., Jacobsen, I. C., Finlayson, G., Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2022, In: Nature Communications. 13, 1, 11 p., 4770.

    Research output: Contribution to journalJournal articlepeer-review

  19. 2021
  20. Published

    Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined

    Lundgren, J. R., Janus, C., Jensen, Simon Birk Kjær, Juhl, C. R., Olsen, L. M., Christensen, R. M., Svane, M. S., Bandholm, Thomas Quaade, Bojsen-Møller, K. N., Blond, Martin Bæk, Jensen, Jens-Erik Beck, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 6 May 2021, In: New England Journal of Medicine. 384, p. 1719-1730 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    A Gut-Intrinsic Melanocortin Signaling Complex Augments L-Cell Secretion in Humans

    Sun, E. W., Iepsen, E. W., Pezos, N., Lumsden, A. L., Martin, A. M., Schober, G., Isaacs, N. J., Rayner, C. K., Nguyen, N. Q., de Fontgalland, D., Rabbitt, P., Hollington, P., Wattchow, D. A., Hansen, Torben, Holm, Jens-Christian, Liou, A. P., Jackson, V. M., Torekov, Signe Sørensen, Young, R. L. & Keating, D. J., 2021, In: Gastroenterology. 161, 2, p. 536-547.e2 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V

    Lubberding, Anniek Frederike, Zhang, J., Lundh, M., Nielsen, Thomas Svava, Søndergaard, M. S., Villadsen, M., Skovhøj, E. Z., Boer, G. A., Hansen, J. B., Thomsen, Morten Bækgaard, Treebak, Jonas Thue, Holst, Jens Juul, Kanters, Jørgen K., Mandrup-Poulsen, Thomas, Jespersen, Thomas, Emanuelli, Brice & Torekov, Signe Sørensen, 2021, In: Scientific Reports. 11, 1, 14 p., 12253.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Fat-Secreted Ceramides Regulate Vascular Redox State and Influence Outcomes in Patients With Cardiovascular Disease

    Akawi, N., Checa, A., Antonopoulos, A. S., Akoumianakis, I., Daskalaki, E., Kotanidis, C. P., Kondo, H., Lee, K., Yesilyurt, D., Badi, I., Polkinghorne, M., Akbar, N., Lundgren, J., Chuaiphichai, S., Choudhury, R., Neubauer, S., Channon, K. M., Torekov, Signe Sørensen, Wheelock, C. E. & Antoniades, C., 2021, In: American College of Cardiology. Symposia. 77, 20, p. 2494-2513

    Research output: Contribution to journalJournal articlepeer-review

  24. Published
  25. Published

    Glucagon-like peptide-1 receptor agonists: The key to healthy weight loss maintenance?

    Lehmann, E. W. & Torekov, Signe Sørensen, 2021, In: Cardiovascular Research. 117, 10, p. E120-E122

    Research output: Contribution to journalComment/debatepeer-review

  26. Published

    Glucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness

    Jujic, A., Nilsson, P. M., Atabaki-Pasdar, N., Dieden, A., Tuomi, T., Franks, P. W., Holst, Jens Juul, Torekov, Signe Sørensen, Ravassa, S., Diez, J., Persson, M., Ahlqvist, E., Melander, O., Gomez, M. F., Groop, L. & Magnusson, M., 2021, In: Diabetes Care. 44, 1, p. 224-230 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined. The Authors Reply

    Jensen, Simon Birk Kjær & Torekov, Signe Sørensen, 2021, In: The New England Journal of Medicine. 385, 6, p. 573-574

    Research output: Contribution to journalLetterpeer-review

  28. Published

    No effects of dapagliflozin, metformin or exercise on plasma glucagon concentrations in individuals with prediabetes: A post hoc analysis from the randomized controlled PRE-D trial

    Clemmensen, K. K. B., Blond, M. B., Amadid, H., Bruhn, L., Vistisen, D., Karstoft, K., Persson, F., Ried-Larsen, M., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Torekov, Signe Sørensen, Quist, J. S., Jorgensen, M. E. & Faerch, K., 2021, In: Diabetes, Obesity and Metabolism. 23, 2, p. 530-539

    Research output: Contribution to journalJournal articlepeer-review

  29. 2020
  30. Published

    Glucose-dependent insulinotropic peptide and risk of cardiovascular events and mortality: a prospective study

    Jujic, A., Atabaki-Pasdar, N., Nilsson, P. M., Almgren, P., Hakaste, L., Tuomi, T., Berglund, L. M., Franks, P. W., Holst, Jens Juul, Prasad, R. B., Torekov, Signe Sørensen, Ravassa, S., Diez, J., Persson, M., Melander, O., Gomez, M. F., Groop, L., Ahlqvist, E. & Magnusson, M., May 2020, In: Diabetologia. 63, 5, p. 1043-1054

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Adults with pathogenic MC4R mutations have increased final height and thereby increased bone mass

    Iepsen, E. W., Zhang, J., Hollensted, M., Madsbad, Sten, Hansen, Torben, Holst, Jens Juul, Jørgensen, Niklas Rye, Holm, Jens-Christian & Torekov, Signe Sørensen, 2020, In: Journal of Bone and Mineral Metabolism. 38, 1, p. 117-125 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Drug-induced blockade of the voltage-gated potassium channel Kv11.1 (hERG-channel) decreases glucose-stimulated insulin secretion and increases insulin sensitivity

    Juhl, C., Burgdorf, J., Knudsen, C., Veedfald, Simon, Holst, Jens Juul, Kanters, Jørgen K. & Torekov, Signe Sørensen, 2020, In: Diabetologia. 63, SUPPL 1, p. S232-S233 2 p., 479.

    Research output: Contribution to journalConference abstract in journal

  33. Published

    Exercise alone and in combination with liraglutide improves cardiorespiratory fitness and physical functioning during weight loss maintenance

    Jensen, Simon Birk Kjær, Janus, C., Lundgren, J. R., Juhl, C. R., Blond, Martin Bæk, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2020, In: Diabetologia. 63, SUPPL 1, p. S290-S290 1 p., 604.

    Research output: Contribution to journalConference abstract in journal

  34. Published

    GLP-1 Receptor Agonist Treatment in Morbid Obesity and Type 2 Diabetes Due to Pathogenic Homozygous Melanocortin-4 Receptor Mutation: A Case Report

    Iepsen, E. W., Have, C. T., Veedfald, Simon, Madsbad, Sten, Holst, Jens Juul, Grarup, Niels, Pedersen, Oluf Borbye, Brandslund, I., Holm, Jens-Christian, Hansen, Torben & Torekov, Signe Sørensen, 2020, In: Cell Reports Medicine. 1, 1, 8 p., 100006.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Gain-of-function mutation in the voltage-gated potassium channel gene KCNQ1 and glucose-stimulated hypoinsulinemia - case report

    Zhang, J., Juhl, C. R., Hylten-Cavallius, L., Olesen, Morten Steen Salling, Linneberg, Allan René, Holst, Jens Juul, Hansen, Torben, Kanters, Jørgen K. & Torekov, Signe Sørensen, 2020, In: B M C Endocrine Disorders. 20, 5 p., 38.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis

    Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., Treebak, J. T., Gillum, M. P., Torekov, S. S., Windeløv, J. A., Hunt, J. E., Kjeldsen, S. A. S., Jepsen, S. L., Vasilopoulou, C. G., Knop, F. K., Ørskov, C. & 7 others, Werge, M. P., Bisgaard, Hanne Cathrine, Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Molecular Metabolism. 42, 18 p., 101080.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Protocol for a single-centre, parallel-group, randomised, controlled, superiority trial on the effects of time-restricted eating on body weight, behaviour and metabolism in individuals at high risk of type 2 diabetes: the REStricted Eating Time (RESET) study

    Quist, Jonas Salling, Jensen, M. M., Clemmensen, K. K. B., Pedersen, H., Bjerre, N., Størling, J., Blond, M. B., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Torekov, Signe Sørensen, Vistisen, D., Jørgensen, M. E., Panda, S., Brock, C., Finlayson, G. & Faerch, K., 2020, In: BMJ Open. 10, 8, 11 p., 037166.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Role of fasting duration and weekday in incretin and glucose regulation

    Clemmensen, K. K. B., Quist, J. S., Vistisen, D., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Holst, Jens Juul, Lauritzen, T., Jørgensen, M. E., Torekov, Signe Sørensen & Færch, K., 2020, In: Endocrine Connections. 9, 4, p. 279-288

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Weight loss-induced improvements of endothelial function and cardiovascular risk factors are maintained with exercise, liraglutide or the combination

    Lundgren, J. R., Bladbjerg, E. M., Janus, C., Gliemann, Lasse, Olsen, L. M., Juhl, C. R., Jensen, Simon Birk Kjær, Thirumathyam, R., Stallknecht, Bente Merete, Holst, Jens Juul, Hove, Jens Dahlgaard, Madsbad, Sten, Antoinades, C. & Torekov, Signe Sørensen, 2020, In: Diabetologia. 63, SUPPL 1, p. S457-S457 1 p., 959.

    Research output: Contribution to journalConference abstract in journalpeer-review

  40. 2019
  41. Published

    Benefit-Risk Assessment of Obesity Drugs: Focus on Glucagon-like Peptide-1 Receptor Agonists

    Christensen, R. M., Juhl, C. R. & Torekov, Signe Sørensen, 2019, In: Drug Safety. 42, 8, p. 957-971 15 p.

    Research output: Contribution to journalReviewpeer-review

  42. Published

    Glukagonlignende peptid 1-receptoragonisten semaglutid

    Boje, A. D., Juhl, C. R., Torekov, Signe Sørensen & Madsbad, Sten, 2019, In: Ugeskrift for Laeger. 181, 5 p., V03190155.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Greater glucagon-like peptide-1 responses to oral glucose are associated with lower central and peripheral blood pressures

    Lundgren, J. R., Faerch, K., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Holst, Jens Juul, Vistisen, D., Jorgensen, M. E., Torekov, Signe Sørensen & Johansen, N. B., 2019, In: Cardiovascular Diabetology. 18, 1, 9 p., 130.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    Habitual activity associates with lower fasting and greater glucose-induced GLP-1 response in men

    Janus, C., Vistisen, D., Amadid, H., Witte, D. R., Lauritzen, T., Brage, S., Bjerregaard, A., Hansen, Torben, Holst, Jens Juul, Jørgensen, M. E., Pedersen, Oluf Borbye, Færch, K. & Torekov, Signe Sørensen, 2019, In: Endocrine Connections. 8, 12, p. 1607–1617 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Protocol for a randomised controlled trial of the combined effects of the GLP-1 receptor agonist liraglutide and exercise on maintenance of weight loss and health after a very low-calorie diet

    Jensen, Simon Birk Kjær, Lundgren, J. R., Janus, C., Juhl, C. R., Olsen, L. M., Rosenkilde, M., Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten & Torekov, Signe Sørensen, 2019, In: BMJ Open. 9, 11, 10 p., e031431.

    Research output: Contribution to journalJournal articlepeer-review

  46. 2018
  47. Published

    Hvordan undgår man, at de tabte kilo kommer på igen?

    Christensen, Bodil Just, Iepsen, E. P. W. & Torekov, Signe Sørensen, 29 May 2018, Forskerzonen.

    Research output: Other contributionNet publication - Internet publicationCommunication

  48. Published

    Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses

    pjx571, pjx571, Mahendran, Y., Jonsson, Anna Elisabet, Gjesing, A. P., Weeke, P. E., Jørgensen, M. E., Færch, K., Witte, D. R., Holst, Jens Juul, Jørgensen, T., Grarup, Niels, Pedersen, Oluf Borbye, drb459, drb459, Torekov, Signe Sørensen, Kanters, Jørgen K. & Hansen, Torben, 2018, In: B M C Genetics. 19, 1, p. 1-9 9 p., 15.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published
  50. Published

    Glucagon-like peptide-1 receptor agonists and cardiovascular disease: from LEADER to EXSCEL

    Torekov, Signe Sørensen, 2018, In: Cardiovascular Research. 114, 10, p. e70-e71 2 p.

    Research output: Contribution to journalComment/debatepeer-review

  51. Published

    Patients with Obesity Caused by Melanocortin-4 Receptor Mutations Can Be Treated with a Glucagon-like Peptide-1 Receptor Agonist

    Iepsen, E. W., Zhang, J., Thomsen, Henrik S., Hansen, E. L., Hollensted, M., Madsbad, Sten, Hansen, Torben, Holst, Jens Juul, Holm, Jens-Christian & Torekov, Signe Sørensen, 2018, In: Cell Metabolism. 28, 1, p. 23-32.e3

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery

    Albrechtsen, Nicolai Jacob Wewer, Geyer, P. E., Doll, S., Treit, P. V., Bojsen-Møller, K. N., Martinussen, C., Jørgensen, N. B., Torekov, Signe Sørensen, Meier, F., Niu, Lili, Santos, A., Keilhauer, E. C., Holst, Jens Juul, Madsbad, Sten & Mann, Matthias, 2018, In: Cell Systems. 7, 6, p. 601-612

    Research output: Contribution to journalJournal articlepeer-review

  53. 2017
  54. Published

    Glucose ingestion causes cardiac repolarization disturbances in type 1 long QT syndrome patients and healthy subjects

    Hyltén-Cavallius, L., Iepsen, E. W., Christiansen, M., Graff, C., Linneberg, Allan René, Pedersen, Oluf Borbye, Holst, Jens Juul, Hansen, Torben, Torekov, Signe Sørensen & Kanters, Jørgen K., Aug 2017, In: Heart Rhythm. 14, 8, p. 1165-1170 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  55. Published

    Health care professionals from developing countries report educational benefits after an online diabetes course

    Albrechtsen, Nicolai Jacob Wewer, Poulsen, K. W., Svensson, L. Ø., Jensen, Lasse X, Holst, Jens Juul & Torekov, Signe Sørensen, 31 May 2017, In: B M C Medical Education. 17, 8 p., 97.

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    Chronic intrahypothalamic rather than subcutaneous liraglutide treatment reduces body weight gain and stimulates the melanocortin receptor system

    Kaineder, K., Birngruber, T., Rauter, G., Obermüller, B., Eichler, J., Münzker, J., Al-Zoughbi, W., Mautner, S. I., Torekov, Signe Sørensen, Hartmann, Bolette, Kotzbeck, P. & Pieber, T. R., 16 May 2017, In: International Journal of Obesity. 41, p. 1263-1270 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  57. Published

    Glucagon-Like Peptide 1: A Predictor of Type 2 Diabetes?

    Larsen, M. P. & Torekov, Signe Sørensen, 2017, In: Journal of Diabetes Research. 2017, 13 p., 7583506.

    Research output: Contribution to journalReviewpeer-review

  58. Published

    Instrumentalization of eating improves weight loss maintenance in obesity

    Christensen, Bodil Just, Iepsen, E. P. W., Lundgren, J. R., Holm, Lotte, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2017, In: Obesity Facts. 10, 6, p. 633-647 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  59. Published
  60. Published

    Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB

    pjx571, pjx571, Lundgren, Jens, Albrechtsen, Nicolai Jacob Wewer, Mahendran, Y., Iepsen, E. P. W., Finocchietto, P., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Obesity Science & Practice. 3, 4, p. 425-433 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  61. 2016
  62. Published

    Proteomics reveals the effects of sustained weight loss on the human plasma proteome

    Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Tyanova, S., Grassl, N., Iepsen, E. P. W., Lundgren, J., Madsbad, Sten, Holst, Jens Juul, Torekov, Signe Sørensen & Mann, Matthias, 22 Dec 2016, In: Molecular Systems Biology. 12, 16 p., 901.

    Research output: Contribution to journalJournal articlepeer-review

  63. Published

    Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels

    pjx571, pjx571, Iepsen, E. P. W., Galijatovic, E. A. A., Mahendran, Y., Lundgren, J. R., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, Dec 2016, In: Metabolomics. 12, 12, p. 1-9 9 p., 181.

    Research output: Contribution to journalJournal articlepeer-review

  64. Published

    Insulin Resistance is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation

    Faerch, K., Vistisen, D., Pacini, G., Torekov, Signe Sørensen, Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Jørgensen, M. E., Ahrén, B. & Holst, Jens Juul, 8 Aug 2016, In: Diabetes. 65, 11, p. 3473-3481 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  65. Published

    Successful weight loss maintenance includes long-term increased meal responses of GLP-1 and PYY3-36

    Iepsen, E. W., Lundgren, J., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, Jun 2016, In: European Journal of Endocrinology. 174, 6, p. 775-784 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  66. Published

    Searching for the physiological role of glucose-dependent insulinotropic polypeptide

    Holst, Jens Juul, Windeløv, Johanne Agerlin, Boer, G. A., Pedersen, Jens, Svendsen, B., Christensen, M., Torekov, Signe Sørensen, Asmar, M., Hartmann, Bolette & Nissen, A., 1 Apr 2016, In: Journal of Diabetes Investigation. 7, S1, p. 8-12 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  67. Published

    Major rapid weight loss induces changes in cardiac repolarization

    Vedel-Larsen, E., Iepsen, E. P. W., Lundgren, J., Graff, C., Struijk, J. J., Hansen, Torben, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Kanters, Jørgen K., 10 Feb 2016, In: Journal of Electrocardiology. 49, 3, p. 467-472 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  68. Published

    Glucose-dependent insulinotropic polypeptide (GIP) is associated with lower LDL but unhealthy fat distribution, independent of insulin: The ADDITION-PRO study

    Møller, C. L., Vistisen, D., Færch, K., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Jørgensen, M. E., Torekov, Signe Sørensen & Holst, Jens Juul, Feb 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 2, p. 485– 493 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  69. Published

    Atrial Natriuretic Peptide in the high normal range is associated with lower prevalence of insulin resistance

    Jujić, A., Nilsson, P. M., Persson, M., Holst, Jens Juul, Torekov, Signe Sørensen, Lyssenko, V., Groop, L., Melander, O. & Magnusson, M., 27 Jan 2016, In: The Journal of clinical endocrinology and metabolism. 101, 4, p. 1372-1380 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  70. 2015
  71. Published

    Response to Comment on Færch et al. GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study. Diabetes 2015;64:2513–2525

    Ferch, K., Torekov, Signe Sørensen, Vistisen, D., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Sandbek, A., Holst, Jens Juul & Jørgensen, M. E., 1 Sep 2015, In: Diabetes. 64, 9, p. e30-e31

    Research output: Contribution to journalComment/debatepeer-review

  72. Published

    Glucagon-Like Peptide-1 (GLP-1) Response to Oral Glucose is Reduced in Pre-diabetes, Screen-detected Type 2 Diabetes and Obesity, and Influenced by Sex: The ADDITION-PRO Study

    Færch, K., Torekov, Signe Sørensen, Vistisen, D., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Sandbæk, A., Holst, Jens Juul & Jørgensen, M. E., Jul 2015, In: Diabetes. 64, p. 2513-25 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  73. Published

    Ny fedmebehandling modvirker knogletab

    Torekov, Signe Sørensen, 17 Jun 2015, In: Dagens Medicin. 1 p.

    Research output: Contribution to journalContribution to newspaper - Comment/debate

  74. Published

    New obesity treatment prevents bone loss during weight loss

    Torekov, Signe Sørensen, 11 Jun 2015

    Research output: Other contributionNet publication - Internet publicationCommunication

  75. Published

    GLP-1 baseret behandling af diabetes og svær overvægt

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2015, In: BestPractice. 9, 4, p. 10-12 3 p.

    Research output: Contribution to journalJournal article

  76. Published

    GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women

    Iepsen, E. P. W., Lundgren, J. R., Hartmann, Bolette, Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, Niklas Rye, Jensen, J. B., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2015, In: The Journal of clinical endocrinology and metabolism. 100, 8, p. 2909 –2917 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  77. Published

    Liraglutide for Type 2 diabetes and obesity: a 2015 update

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2015, In: Expert Review of Cardiovascular Therapy. 13, 7, p. 753-67 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  78. Published

    Online diabeteskursus er en kæmpe succes

    Torekov, Signe Sørensen, 2015, In: People.

    Research output: Contribution to journalJournal article

  79. Published

    Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss

    Iepsen, E. W., Lundgren, J., Dirksen, C., Jensen, J., Pedersen, Oluf Borbye, Hansen, Torben, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2015, In: International journal of obesity (2005). 39, 5, p. 834-41 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  80. 2014
  81. Published

    Therapies for inter-relating diabetes and obesity - GLP-1 and obesity

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, Dec 2014, In: Expert Opinion on Pharmacotherapy. 15, 17, p. 2487-500 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  82. Published

    Dose response of continuous subcutaneous infusion of recombinant glucagon-like peptide-1 in combination with metformin and sulphonylurea over 12 weeks in patients with type 2 diabetes mellitus

    Torekov, Signe Sørensen, Holst, Jens Juul & Ehlers, M. R., May 2014, In: Diabetes, Obesity and Metabolism. 16, 5, p. 451-6 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  83. Published

    A functional amino acid substitution in the glucose-dependent insulinotropic polypeptide receptor (GIPR) gene is associated with lower bone mineral density and increased fracture risk

    Torekov, Signe Sørensen, Harsløf, T., Rejnmark, L., Eiken, P., Jensen, Jens-Erik Beck, Herman, A. P., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul & Langdahl, B. L., Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 4, p. E729-33 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  84. Published

    KCNQ1 Long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia

    Torekov, Signe Sørensen, Iepsen, E., Christiansen, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K. & Hansen, Torben, Apr 2014, In: Diabetes. 63, 4, p. 1315-1325 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  85. 2012
  86. Published

    Impact of postprandial glycaemia on health and prevention of disease

    Blaak, E. E., Antoine, J., Benton, D., Björck, I., Bozzetto, L., Brouns, F., Diamant, M., Dye, L., Hulshof, T., Holst, Jens Juul, Lamport, D. J., Laville, M., Lawton, C. L., Meheust, A., Nilson, A., Normand, S., Rivellese, A. A., Theis, S., Torekov, Signe Sørensen & Vinoy, S., 2012, In: Obesity Reviews. 13, 10, p. 923-984

    Research output: Contribution to journalJournal articlepeer-review

  87. Published

    Leptin og dens betydning for vægtvedligeholdelse

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2012, In: Klinisk biokemi i Norden. 24, 4, p. 8-15 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  88. 2011
  89. Published

    An overview of once-weekly glucagon-like peptide-1 receptor agonists--available efficacy and safety data and perspectives for the future

    Madsbad, Sten, Kielgast, U., Asmar, M., Deacon, Carolyn F., Torekov, Signe Sørensen & Holst, Jens Juul, May 2011, In: Diabetes, Obesity and Metabolism. 13, 5, p. 394-407 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  90. Published

    Dose response of subcutaneous GLP-1 infusion in patients with type 2 diabetes

    Torekov, Signe Sørensen, Kipnes, M. S., Harley, R. E., Holst, Jens Juul & Ehlers, M. R., 2011, In: Diabetes, Obesity and Metabolism. 13, 7, p. 639-43 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  91. Published

    Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1

    Torekov, S. S., Ma, L., Grarup, N., Hartmann, B., Hainerová, I. A., Kielgast, U., Kissow, H., Rosenkilde, M., Lebl, J., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Madsen, O. D., Wang, J., Linneberg, A., Madsbad, S., Holst, J. J., Hansen, T., Pedersen, O. & 1 others, GIANT Consortium, G. C., 2011, In: Diabetologia. 54, 11, p. 2820-31 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  92. Published

    Obesity - an indication for GLP-1 treatment? Obesity pathophysiology and GLP-1 treatment potential

    Torekov, Signe Sørensen, Madsbad, Sten & Holst, Jens Juul, 2011, In: Obesity Reviews. 12, 8, p. 593-601 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  93. 2010
  94. Published

    Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity

    Gjesing, A. P., Larsen, L. H., Torekov, S. S., Hainerová, I. A., Kapur, R., Johansen, A., Albrechtsen, A., Boj, S., Holst, B., Harper, A., Urhammer, S. A., Borch-Johnsen, K., Pisinger, C. H., Echwald, S. M., Eiberg, H. R. L., Astrup, A., Lebl, J., Ferrer, J., Schwartz, T. W., Hansen, T. & 1 others, Pedersen, Oluf Borbye, 2010, In: P L o S One. 5, 4, 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  95. 2008
  96. Published

    Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation

    Andreasen, C. H., Stender-Petersen, K. L., Mogensen, M. S., Torekov, Signe Sørensen, Wegner, L., Andersen, G., Nielsen, A. L., Albrechtsen, Anders, Borch-Johnsen, K., Rasmussen, S. S., Clausen, J. O., Sandbaek, A., Lauritzen, T., Hansen, L., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, T., 2008, In: Diabetes. 57, 1, p. 95-101 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  97. 2007
  98. Published

    Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes

    Larsen, L. H., Rose, C. S., Sparsø, T., Overgaard, J., Torekov, Signe Sørensen, Grarup, Niels, Jensen, Dan Funck, Albrechtsen, Anders, Andersen, G., Ek, J., Glümer, C., Borch-Johnsen, K., Jørgensen, Tina, Hansen, Teis Schjals & Pedersen, Oluf Borbye, 2007, In: International Journal of Obesity. 31, 2, p. 365-70 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  99. 2006
  100. Published

    Association between neuromedin U gene variants and overweight and obesity

    Hainerová, I., Torekov, Signe Sørensen, Ek, J., Finková, M., Borch-Johnsen, K., Jørgensen, T., Madsen, O. D., Lebl, J., Hansen, Torben & Pedersen, Oluf Borbye, 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 12, p. 5057-63 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  101. Published

    Variants in the 5' region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects

    Torekov, Signe Sørensen, Larsen, L. H., Andersen, G., Albrechtsen, Anders, Glümer, C., Borch-Johnsen, K., Jørgensen, Tina, Hansen, Teis Schjals & Pedersen, Oluf Borbye, 2006, In: Diabetologia. 49, 11, p. 2653-8 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  102. 2005
  103. Published

    Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes

    Torekov, Signe Sørensen, Larsen, L. H., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Holst, Jens Juul, Madsen, O. D., Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Diabetes. 54, 7, p. 2261-5 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  104. 2004
  105. Published

    Large-scale studies of the HphI insulin gene variable-number-of-tandem-repeats polymorphism in relation to Type 2 diabetes mellitus and insulin release

    Hansen, S. K., Gjesing, A. P., Rasmussen, S. K., Glümer, C., Urhammer, S. A., Andersen, G., Rose, C. S., Drivsholm, Thomas, Torekov, Signe Sørensen, Jensen, D. P., Ekstrøm, C. T., Borch-Johnsen, K., Jørgensen, T., Nymark, C. M., Hansen, T. & Pedersen, O., 1 Jun 2004, In: Diabetologia. 47, 6, p. 1079-87 9 p.

    Research output: Contribution to journalJournal articlepeer-review

ID: 5761