Signe Mathiasen

Signe Mathiasen

Assistant Professor, Tenure Track Assistant Professor

Member of:


    1. 2023
    2. Published

      Adhesion G protein‐coupled receptor's structure, function and role in biology—Status from the 10th adhesion GPCR workshop in Copenhagen, 2022

      Rosenkilde, Mette & Mathiasen, Signe, 2023, In: Basic & clinical pharmacology & toxicology. 133, 4, p. 281-284

      Research output: Contribution to journalEditorialResearchpeer-review

    3. Published

      Re-routing GPR56 signalling using Gα12/13 G protein chimeras

      Faas, Felix, Nørskov, Amalie, Holst, Peter Johannes, Andersson, A. M., Qvortrup, K., Mathiasen, Signe & Rosenkilde, Mette, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 378-389

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. 2021
    5. Single-molecule FRET imaging of GPCR dimers in living cells

      Asher, W. B., Geggier, P., Holsey, M. D., Gilmore, G. T., Pati, A. K., Meszaros, J., Terry, D. S., Mathiasen, Signe, Kaliszewski, M. J., McCauley, M. D., Govindaraju, A., Zhou, Z., Harikumar, K. G., Jaqaman, K., Miller, L. J., Smith, A. W., Blanchard, S. C. & Javitch, J. A., 2021, In: Nature Methods. 18, 4, p. 397-405 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. 2020
    7. G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3

      Mathiasen, Signe, Palmisano, T., Perry, N. A., Stoveken, H. M., Vizurraga, A., McEwen, D. P., Okashah, N., Langenhan, T., Inoue, A., Lambert, N. A., Tall, G. G. & Javitch, J. A., Dec 2020, In: Nature Chemical Biology. 16, 12, p. 1343–1350

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Agonist-induced formation of unproductive receptor-G12 complexes

      Okashah, N., Wright, S. C., Kawakami, K., Mathiasen, Signe, Zhou, J., Lu, S., Javitch, J. A., Inoue, A., Bouvier, M. & Lambert, N. A., 1 Sep 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 35, p. 21723-21730 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Novel Fluorescent Ligands Enable Single-Molecule Localization Microscopy of the Dopamine Transporter

      Guthrie, D. A., Klein Herenbrink, Carmen, Lycas, M. D., Ku, T., Bonifazi, A., Devree, B. T., Mathiasen, Signe, Javitch, J. A., Grimm, J. B., Lavis, L., Gether, Ulrik & Newman, A. H., 2020, In: ACS Chemical Neuroscience. 11, 20, p. 3288-3300 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. 2018
    11. Published

      Single Proteoliposome High-Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs

      Walsh, S. M., Mathiasen, Signe, Christensen, S. M., Fay, J. F., King, C., Provasi, D., Borrero, E., Rasmussen, Søren Gøgsig Faarup, Fung, J. J., Filizola, M., Hristova, K., Kobilka, B., Farrens, D. L. & Stamou, Dimitrios, 2018, In: Biophysical Journal. 115, 2, p. 300-312 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. 2017
    13. Published

      Extreme vetting of dopamine receptor oligomerization

      Asher, W. B., Mathiasen, Signe, Holsey, M. D., Grinnell, S. G., Lambert, N. A. & Javitch, J. A., 2017, Receptors. Humana Press, p. 99-127 29 p. (Receptors, Vol. 33).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    14. Published

      Single-molecule analysis of ligand efficacy in β2AR-G-protein activation

      Gregorio, G. G., Masureel, M., Hilger, D., Terry, D. S., Juette, M., Zhao, H., Zhou, Z., Perez-Aguilar, J. M., Hauge, M., Mathiasen, Signe, Javitch, J. A., Weinstein, H., Kobilka, B. K. & Blanchard, S. C., 2017, In: Nature. 547, 7661, p. 68–73

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. 2016
    16. Published

      Electronic tuning of self-healing fluorophores for live-cell and single-molecule imaging

      Zheng, Q., Jockusch, S., Zhou, Z., Altman, R. B., Zhao, H., Asher, W., Holsey, M., Mathiasen, Signe, Geggier, P., Javitch, J. A. & Blanchard, S. C., 2016, In: Chemical Science. 8, 1, p. 755-762 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. 2015
    18. Published

      Impact of PI(3,4,5)P3-Mediated beta-Arrestin-1 Recruitment on Structure of Asymmetric Lipid Bilayers: Biophysical Society Annual Meeting. Baltimore, Maryland, Febr. 7-11 2015

      Nzulumike, A. N. O., Mathiasen, Signe, Mahoney, J. P., Cardenas Gomez, M., Stamou, Dimitrios & Mortensen, Kell, 7 Feb 2015, In: Biophysical Journal. 108, 2, Suppl., p. 342A-342A

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    19. Published

      CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature

      Miller, S. E., Mathiasen, Signe, Bright, N. A., Pierre, F., Kelly, B. T., Kladt, N., Schauss, A., Merrifield, C. J., Stamou, Dimitrios, Höning, S. & Owen, D. J., 2015, In: Developmental Cell. 33, 2, p. 163-175 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Membrane curvature bends the laws of physics and chemistry

      Iversen, L., Mathiasen, Signe, Larsen, J. B. & Stamou, Dimitrios, 2015, In: Nature Chemical Biology. 11, 11, p. 822-825 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. 2014
    22. Published

      Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes

      Mathiasen, Signe, Christensen, S. M., Fung, J. J., Rasmussen, Søren Gøgsig Faarup, Fay, J. F., Jørgensen, S. K., Veshaguri, S., Farrens, D. L., Kiskowski, M., Kobilka, B. & Stamou, Dimitrios, 2014, In: Nature Methods. 11, p. 931-934 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. 2013
    24. Published

      Biophysical characterization of GPCR oligomerization

      Mathiasen, Signe, 2013, Department of Chemistry, Faculty of Science, University of Copenhagen. 167 p.

      Research output: Book/ReportPh.D. thesisResearch

    25. Published

      Developing an Assay to Probe Activtion and Conformational Dynamics of beta 2-Adrenergic Receptor on Single Molecule Level

      Veshaguri, S., Tutkus, M., Lundgaard, C. V., Tonnesen, A., Mathiasen, Signe, Jorgensen, S. K., Iversen, L., Hatzakis, Nikos, Rasmussen, Søren Gøgsig Faarup & Stamou, Dimitrios, 2013, In: Biophysical Journal. 104, 2, 1 p.

      Research output: Contribution to journalConference abstract in journalResearch

    26. 2011
    27. Published

      Particle-dissociating peptides

      Brown, Stanley & Mathiasen, Signe, 4 Jan 2011, In: Advanced Materials. 23, 1, p. 132-135 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 16152685