Pia Rengtved Lundegaard

Pia Rengtved Lundegaard

Assistant Professor


  1. 2024
  2. Published

    LiverZap: a chemoptogenetic tool for global and locally restricted hepatocyte ablation to study cellular behaviours in liver regeneration

    Ambrosio Galindo, Elizabeth Mayela, Bailey, C. S. L., Unterweger, Iris Anne, Christensen, J. B., Bruchez, M. P., Lundegaard, Pia Rengtved & Ober, Elke, 2024, In: Development (Cambridge). 151, 4, p. 1-18

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Loss of Cardiac Splicing Regulator RBM20 Is Associated With Early-Onset Atrial Fibrillation

    Vad, Oliver Tim Bundgaard, Angeli, Elisavet, Liss, M., Ahlberg, Gustav, Andreasen, Laura Korsholm, Christophersen, I. E., Hansen, Camilla Collin, Møller, S., Hellsten, Ylva, Haunsø, Stig, Tveit, A., Svendsen, Jesper Hastrup, Gotthardt, M., Lundegaard, Pia Rengtved & Olesen, Morten Steen Salling, 2024, In: JACC: Basic to Translational Science. 9, 2, p. 163-180

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2023
  5. Published

    Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics

    Unterweger, Iris Anne, Klepstad, J., Hannezo, E., Lundegaard, Pia Rengtved, Trusina, Ala & Ober, Elke, 2023, In: PLOS Biology. 21, 10, 30 p., e3002315.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Outlining cardiac ion channel protein interactors and their signature in the human electrocardiogram

    Maurya, S., Mills, Robert William, Kahnert, Konstantin, Chiang, D. Y., Bertoli, G., Lundegaard, Pia Rengtved, Duran, M. P. H., Zhang, M., Rothenberg, E., George, A. L., MacRae, C. A., Delmar, M. & Lundby, Alicia, 2023, In: Nature Cardiovascular Research. 2, 7, p. 673-692 38 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2022
  8. Published

    A Multi-Site Assessment of Anesthetic Overdose, Hypothermic Shock, and Electrical Stunning as Methods of Euthanasia for Zebrafish (Danio rerio) Embryos and Larvae

    Mocho, J. P., Lang, F., Valentin, G., Bedu, S., McKimm, R., Ramos, J., Torres, Y. S., Wheatley, S. E., Higgins, J., Millington, M. E., Lundegaard, Pia Rengtved, Valverde, R. C., Jenčič, V. & von Krogh, K., Apr 2022, In: Biology. 11, 4, p. 1-17 546.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Communication and Implementation of humane killing Of laboratory fish (felasa Working group recommendations)

    Mocho, J. P., McKimm, R., Ramos, J., Lundegaard, Pia Rengtved, Jenčič, V. & von Krogh, K., 2022, In: Laboratory Animals. 56, S1, p. 42-42 S3B3.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  10. Published

    Genetic Variants Close to TTN, NKX2-5, and MYH6 Associate With AVNRT

    Andreasen, L., Ahlberg, G., Ægisdóttir, H. M., Sveinbjörnsson, G., Lundegaard, P. R., Hartmann, J. P., Paludan-Müller, C., Hadji-Turdeghal, K., Ghouse, J., Pehrson, S., Jensen, H. K., Riahi, S., Hansen, J., Sandgaard, N., Sørensen, E., Banasik, K., Sækmose, S. G., Bruun, M. T., Hjalgrim, H., Erikstrup, C. & 18 others, Pedersen, Ole Birger Vesterager, Wittig, M., Haunsø, Stig, Ostrowski, Sisse Rye, Genomic Consortium, D., Franke, A., Brunak, Søren, Kanters, Jørgen K., Ellervik, Christina, Bundgård, Henning, Ullum, H., Gudbjartsson, D. F., Thorsteinsdottir, U., Holm, H., Arnar, D. O., Stefansson, K., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2022, In: Circulation Research. 131, 10, p. 862-865

    Research output: Contribution to journalLetterResearchpeer-review

  11. Published

    Integration of multiple imaging platforms to uncover cardiovascular defects in adult zebrafish

    Bensimon-Brito, A., Boezio, G. L. M., Cardeira-da-Silva, J., Wietelmann, A., Ramkumar, S., Lundegaard, Pia Rengtved, Helker, C. S. M., Ramadass, R., Piesker, J., Nauerth, A., Mueller, C. & Stainier, D. Y. R., 2022, In: Cardiovascular Research. 118, 12, p. 2665–2687

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Polygenic risk score for ACE-inhibitor-associated cough based on the discovery of new genetic loci

    Ghouse, J., Tragante, V., Muhammad, A., Ahlberg, G., Skov, M. W., Roden, D. M., Jonsdottir, I., Andreasen, L., Lundegaard, P. R., Trudsø, L. C., Banasik, K., Brunak, S., Ostrowski, S. R., Torp-Pedersen, C., Pedersen, O. V., Sørensen, E., Køber, L., Iversen, K., Thorsteinsdottir, U., Thorgeirsson, G. & 8 others, Ullum, H., Gudbjartsson, D. F., Mosley, J. D., Holm, H., Stefansson, K., Bundgård, Henning, Olesen, Morten Steen Salling & eMERGE consortium, E. C., 2022, In: European Heart Journal. 43, 45, p. 4707–4718

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2021
  14. Published

    Integration of Scandinavian genetic data with UK biobank data implicates the RBM20 gene with atrial fibrillation pathogenesis

    Vad, O. B., Angeli, Elisavet, Liss, M., Ahlberg, G., Andreasen, L., Christophersen, I. E., Tveit, A., Haunsø, Stig, Svendsen, Jesper Hastrup, Lundegaard, Pia Rengtved, Gotthardt, M. & Olesen, Morten Steen Salling, 2021, In: European Heart Journal. 42, p. 3319-3319 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  15. Published

    Quantitative proteome comparison of human hearts with those of model organisms

    Linscheid, N., Santos, A., Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2020
  17. Published

    Early-onset atrial fibrillation patients show reduced left ventricular ejection fraction and increased atrial fibrosis

    Andreasen, Laura Korsholm, Bertelsen, L., Ghouse, Jonas, Lundegaard, Pia Rengtved, Ahlberg, G., Refsgaard, L., Rasmussen, T. B., Eiskjær, H., Haunsø, Stig, Vejlstrup, N., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2020, In: Scientific Reports. 10, 1, 8 p., 10039.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease

    Nielsen, J. B., Rom, O., Surakka, I., Graham, S. E., Zhou, W., Roychowdhury, T., Fritsche, L. G., Taliun, S. A. G., Sidore, C., Liu, Y., Gabrielsen, M. E., Skogholt, A. H., Wolford, B., Overton, W., Zhao, Y., Chen, J., Zhang, H., Hornsby, W. E., Acheampong, A., Grooms, A. & 30 others, Schaefer, A., Zajac, G. J. M., Villacorta, L., Zhang, J., Brumpton, B., Loset, M., Rai, V., Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Taylor, K. D., Palmer, N. D., Chen, Y., Choi, S. H., Lubitz, S. A., Ellinor, P. T., Barnes, K. C., Daya, M., Rafaels, N., Weiss, S. T., Lasky-Su, J., Tracy, R. P., Vasan, R. S., Cupples, L. A., Mathias, R. A., Yanek, L. R., Becker, L. C., Peyser, P. A., Bielak, L. F., Smith, J. A. & Aslibekyan, S., 2020, In: Nature Communications. 11, 1, 12 p., 6417.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Rare coding variants in MYH6 are associated with atrial fibrillation: results from 45,596 exomes representing the general population

    Vad, O. B., Paludan-Muller, C., Ahlberg, G., Andreasen, L., Refsgaard, L., Lundegaard, Pia Rengtved, Haunsø, Stig, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2020, In: European Heart Journal. 41, p. 342-342

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  20. Published

    Rare variants in HCN4 identified in the general population are associated with complete atrioventricular (AV) block, 1. degree AV block and bundle branch block, results from 50.000 exomes

    Jensen, J. S., Vad, O. B., Paludan-Mueller, C., Lundegaard, Pia Rengtved, Svendsen, Jesper Hastrup, Haunsø, Stig, Bundgård, Henning & Olesen, Morten Steen Salling, 2020, In: European Journal of Human Genetics. 28, SUPPL 1, p. 271-272 P05.47.B.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  21. 2019
  22. Published

    Early sarcomere and metabolic defects in a zebrafish pitx2c cardiac arrhythmia model

    Collins, M. M., Ahlberg, G., Hansen, Camilla Collin, Guenther, S., Marín-Juez, R., Sokol, A. M., El-Sammak, H., Piesker, J., Hellsten, Ylva, Olesen, Morten Steen Salling, Stainier, D. Y. R. & Lundegaard, Pia Rengtved, 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 48, p. 24115-24121

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Reappraisal of variants previously linked with sudden infant death syndrome: results from three population-based cohorts

    Paludan-Müller, Christian, Ghouse, Jonas, Vad, O. B., Herfelt, C. B., Lundegaard, Pia Rengtved, Ahlberg, G., Schmitt, Nicole, Svendsen, Jesper Hastrup, Haunsø, Stig, Bundgård, Henning, Hansen, Torben, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2019, In: European Journal of Human Genetics. 27, 9, p. 1427-1435

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2018
  25. Published

    Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish

    Sokol, A. M., Uszczynska-Ratajczak, B., Collins, M. M., Bazala, M., Topf, U., Lundegaard, Pia Rengtved, Sugunan, S., Guenther, S., Kuenne, C., Graumann, J., Chan, S. S. L., Stainier, D. Y. R. & Chacinska, A., Nov 2018, In: PLOS Genetics. 14, 11, p. e1007743 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Atrium-specific ion channels in the zebrafish: A role of Iin atrial repolarization

    Skarsfeldt, M. A., Bomholtz, Sofia Hammami, Lundegaard, Pia Rengtved, Lopez-Izquierdo, A., Tristani-Firouzi, M. & Bentzen, Bo Hjorth, Jul 2018, In: Acta Physiologica (Print). 223, 3, 17 p., e13049.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Microtubule Regulation of Kv7 Channels Orchestrates cAMP-Mediated Vasorelaxations in Rat Arterial Smooth Muscle

    Lindman, J., Khammy, M. M., Lundegaard, Pia Rengtved, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: Hypertension. 71, 2, p. 336-345 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    PKD Phosphorylation as Novel Pathway of KV11.1 Regulation

    Steffensen, Annette Buur, Bomholtz, Sofia Hammami, Andersen, M. N., Olsen, Jesper Velgaard, Mutsaers, N., Lundegaard, Pia Rengtved, Lundby, Alicia & Schmitt, Nicole, 2018, In: Cellular Physiology and Biochemistry. 47, 4, p. 1742-1750 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation

    Ahlberg, G., Refsgaard, L., Lundegaard, Pia Rengtved, Andreasen, Laura Korsholm, Ranthe, M. F., Linscheid, N., Nielsen, J. B., Melbye, M., Haunsø, Stig, Sajadieh, Ahmad, Camp, L., Olesen, Søren-Peter, Rasmussen, Simon, Lundby, Alicia, Ellinor, P. T., Holst, A. G., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2018, In: Nature Communications. 9, 1, 11 p., 4316.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2017
  31. Published

    Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

    Diness, Jonas Goldin, Skibsbye, L., Simó-Vicens, R., Louro Larupa dos Santos, J., Lundegaard, Pia Rengtved, Citerni, C., Sauter, D. R. P., Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, U. S., Jespersen, Thomas, Grunnet, Morten & Bentzen, Bo Hjorth, 10 Oct 2017, In: Circulation: Arrhythmia and Electrophysiology. 10, 19 p., e005125.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2015
  33. Published

    Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone

    Jepps, Thomas Andrew Qvistgaard, Carr, G., Lundegaard, Pia Rengtved, Olesen, Søren-Peter & Greenwood, I. A., 15 Dec 2015, In: Journal of Physiology. 593, 24, p. 5325-40 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    MEK Inhibitors Reverse cAMP-Mediated Anxiety in Zebrafish

    Lundegaard, Pia Rengtved, Anastasaki, C., Grant, N. J., Sillito, R. R., Zich, J., Zeng, Z., Paranthaman, K., Larsen, A. P., Armstrong, J. D., Porteous, D. J. & Patton, E. E., 22 Oct 2015, In: Chemistry & Biology. 22, 10, p. 1335-1346 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2012
  36. Published

    Small molecule screening identifies targetable zebrafish pigmentation pathways

    Colanesi, S., Taylor, K. L., Temperley, N. D., Lundegaard, Pia Rengtved, Liu, D., North, T. E., Ishizaki, H., Kelsh, R. N. & Patton, E. E., Mar 2012, In: Pigment Cell & Melanoma Research. 25, 2, p. 131-43 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2008
  38. Published

    mc1r Pathway regulation of zebrafish melanosome dispersion

    Richardson, J., Lundegaard, Pia Rengtved, Reynolds, N. L., Dorin, J. R., Porteous, D. J., Jackson, I. J. & Patton, E. E., Dec 2008, In: Zebrafish. 5, 4, p. 289-95 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Deletion of the pluripotency-associated Tex19.1 gene causes activation of endogenous retroviruses and defective spermatogenesis in mice

    Ollinger, R., Childs, A. J., Burgess, H. M., Speed, R. M., Lundegaard, Pia Rengtved, Reynolds, N., Gray, N. K., Cooke, H. J. & Adams, I. R., 2008, In: P L o S Genetics. 4, 9, p. e1000199

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2005
  41. Published

    Combining etoposide and dexrazoxane synergizes with radiotherapy and improves survival in mice with central nervous system tumors

    Hofland, K. F., Thougaard, A. V., Dejligbjerg, M., Jensen, L. H., Kristjansen, P. E. G., Lundegaard, Pia Rengtved, Sehested, M. & Jensen, Peter, 15 Sep 2005, In: Clinical Cancer Research. 11, 18, p. 6722-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Immunohistochemical detection of the apoptosis-related proteins FADD, FLICE, and FLIP in Langerhans cell histiocytosis

    Bank, M. I., Gudbrand, C., Lundegaard, Pia Rengtved, Carstensen, H., Fadeel, B., Henter, J. & Petersen, B. L., Jun 2005, In: Journal of Pediatric Hematology/Oncology. 27, 6, p. 301-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2003
  44. Published

    Unusual renal mesenchymoma with unknown malignant potential in an infant

    Petersen, B. L., Lundegaard, Pia Rengtved, Rechnitzer, C. & Graem, N., Mar 2003, In: Medical and Pediatric Oncology. 40, 3, p. 190-2 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    High expression of markers of apoptosis in Langerhans cell histiocytosis

    Petersen, B. L., Lundegaard, Pia Rengtved, Bank, M. I. & Carstensen, H., Feb 2003, In: Histopathology. 42, 2, p. 186-93 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2002
  47. Published

    p53 expression in biopsies from children with Langerhans cell histiocytosis

    Bank, M. I., Lundegaard, Pia Rengtved, Carstensen, H. & Petersen, B. L., Dec 2002, In: Journal of Pediatric Hematology/Oncology. 24, 9, p. 733-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 45850564