Nils Billestrup

Nils Billestrup

Professor


  1. 2024
  2. Published
  3. 2023
  4. Published

    Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding

    Urizar, A. I., Prause, Michala Cecilie Burstein, Ingerslev, L. R., Wortham, M., Sui, Y., Sander, M., Williams, K., Barrès, Romain, Larsen, M. R., Christensen, G. L. & Billestrup, Nils, 2023, In: Cell Death and Disease. 14, 7, 16 p., 399.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice

    Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Sørensen, C., Størling, J., Moritz, Thomas, Mariño, E. & Billestrup, Nils, 2023, In: International Journal of Molecular Sciences. 24, 5, 17 p., 4533.

    Research output: Contribution to journalJournal articlepeer-review

  6. 2022
  7. Published

    Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells

    Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Williams, K., Barrès, Romain & Billestrup, Nils, 2022, In: Journal of Biological Chemistry. 298, 9, 14 p., 102312.

    Research output: Contribution to journalJournal articlepeer-review

  8. 2021
  9. Published

    Butyrate protects pancreatic beta cells from cytokine-induced dysfunction

    Prause, Michala Cecilie Burstein, Pedersen, Signe Schultz, Tsonkova, V., Qiao, M. & Billestrup, Nils, 2021, In: International Journal of Molecular Sciences. 22, 19, 18 p., 10427.

    Research output: Contribution to journalJournal articlepeer-review

  10. 2019
  11. Published

    Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1 beta is associated with changes in expression of beta-cell maturity genes and associated histone modifications

    Urizar, A. I., Prause, Michala Cecilie Burstein, Wortham, M., Sui, Y., Thams, P., Sander, M., Christensen, G. L. & Billestrup, Nils, 2019, In: Molecular and Cellular Endocrinology. 496, 12 p., 110524 .

    Research output: Contribution to journalReviewpeer-review

  12. 2018
  13. Published

    Characterization of the Molecular Mechanisms Underlying Glucose Stimulated Insulin Secretion from Isolated Pancreatic β-cells Using Post-translational Modification Specific Proteomics (PTMomics)

    Kang, T., Jensen, P., Huang, H., Lund Christensen, G., Billestrup, Nils & Larsen, M. R., Jan 2018, In: Molecular and Cellular Proteomics. 17, 1, p. 95-110 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. 2017
  15. Published

    In-vitro and in-vivo studies supporting the therapeutic potential of ZP3022 in diabetes

    Skarbaliene, J., Rigbolt, K. T., Fosgerau, K. & Billestrup, Nils, 15 Nov 2017, In: European Journal of Pharmacology. 815, p. 181-189 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo

    Berchtold, L. A., Miani, M., Diep, T. A., Madsen, A. N., Cigliola, V., Colli, M., Miskovic Krivokapic, Jelena, Pociot, Flemming, Eizirik, D. L., Meda, P., Holst, Birgitte, Billestrup, Nils & Storling, J., 2017, In: Molecular and Cellular Endocrinology. 448, p. 108-121 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  17. 2016
  18. Published

    Regulation of Pancreatic Alpha Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) in vitro.

    Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p., 27479530 .

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Regulation of Pancreatic α-Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) In Vitro

    Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    Aberrant accumulation of the diabetes autoantigen GAD65 in Golgi membranes in conditions of ER stress and autoimmunity

    Phelps, E. A., Cianciaruso, C., Michael, I. P., Pasquier, M., Kanaani, J., Nano, R., Lavallard, V., Billestrup, Nils, Hubbell, J. A. & Baekkeskov, S., Sep 2016, In: Diabetes. 65, 9, p. 2686-2699

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    TRAF2 mediates JNK and STAT3 activation in response to IL-1β and IFNγ and facilitates apoptotic death of insulin-producing β-cells

    Prause, Michala Cecilie Burstein, Berchtold, L. A., Urizar, A. I., Trauelsen, Mette, Billestrup, Nils, Mandrup-Poulsen, Thomas & Størling, J., 15 Jan 2016, In: Molecular and Cellular Endocrinology. 420, p. 24-36 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Inflammatory Cytokines Stimulate Bone Morphogenetic Protein-2 Expression and Release from Pancreatic Beta Cells

    Urizar, A. I., Friberg, J., Christensen, D. P., Christensen, G. L. & Billestrup, Nils, 1 Jan 2016, In: Journal of Interferon & Cytokine Research. 36, 1, p. 20-29

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1 beta-Induced Apoptosis Associated with Abrogated Myc Expression

    Prause, Michala Cecilie Burstein, Mayer, C. M., Brorsson, C., Frederiksen, K. S., Billestrup, Nils, Storling, J. & Mandrup-Poulsen, Thomas, 2016, In: Journal of Diabetes Research. 2016, 15 p., 1312705.

    Research output: Contribution to journalJournal articlepeer-review

  24. 2015
  25. Published

    Surface-expressed insulin receptors as well as IGF-I receptors both contribute to the mitogenic effects of human insulin and its analogues

    Lundby, A., Bolvig, P., Hegelund, A. C., Hansen, B. F., Worm, J., Lützen, A., Billestrup, Nils, Bonnesen, C. & Oleksiewicz, M. B., Jul 2015, In: Journal of Applied Toxicology. 35, 7, p. 842-850 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    The Anti-diabetic Effects of GLP-1-gastrin Dual Agonist ZP3022 in ZDF rats

    Skarbaliene, J., Secher, T., Jelsing, J., Ansarullah, Neerup, T. S. R., Billestrup, Nils & Fosgerau, K., Jul 2015, In: Peptides. 69, p. 47-55 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Bone morphogenetic protein 4 inhibits insulin secretion from rodent beta cells through regulation of calbindin1 expression and reduced voltage-dependent calcium currents

    Christensen, G. L., Jacobsen, M. L. B., Wendt, A., Mollet, I. G., Friberg, J., Frederiksen, K. S., Meyer, M., Bruun, C., Eliasson, L. & Billestrup, Nils, Jun 2015, In: Diabetologia. 58, 6, p. 1282-1290 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    Compartmentalization of GABA synthesis by GAD67 differs between pancreatic beta cells and neurons

    Kanaani, J., Cianciaruso, C., Phelps, E. A., Pasquier, M., Brioudes, E., Billestrup, Nils & Baekkeskov, S., 2015, In: PLOS ONE. 10, 2, p. 1-24 24 p., e0117130.

    Research output: Contribution to journalJournal articlepeer-review

  29. 2014
  30. Published

    Co-ordinated regulation of neurogenin-3 expression in the maternal and fetal pancreas during pregnancy

    Søstrup, B., Gaarn, L. W., Nalla, A., Billestrup, Nils & Nielsen, Jens Høiriis, Nov 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1190-7 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Impact of fetal and neonatal environment on beta cell function and development of diabetes

    Nielsen, Jens Høiriis, Haase, T. N., Jaksch, C., Nalla, A., Søstrup, B., Nalla, A. A., Larsen, L., Rasmussen, M., Dalgaard, L. T., Gaarn, L. W., Thams, P., Kofod, H. & Billestrup, Nils, Nov 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1109-22 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Implications for the offspring of circulating factors involved in beta cell adaptation in pregnancy

    Nalla, A., Ringholm, L., Søstrup, B., Højrup, P., Thim, L., Levery, S. B., Vakhrushev, Sergey, Billestrup, Nils, Mathiesen, Elisabeth, Damm, Peter & Nielsen, Jens Høiriis, Nov 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1181-9 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    CRFR1 activation protects against cytokine-induced beta cell death

    Blaabjerg, L., Christensen, G. L., Matsumoto, M., van der Meulen, T., Huising, M. O., Billestrup, Nils & Vale, W., 16 Oct 2014, In: Journal of Molecular Endocrinology. 53, p. 417-427 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Inhibition of beta cell growth and function by bone morphogenetic proteins

    Bruun, C., Christensen, G. L., Jacobsen, M. L. B., Kanstrup, M. B., Jensen, P. R., Fjordvang, H., Mandrup-Poulsen, Thomas & Billestrup, Nils, 27 Sep 2014, In: Diabetologia. 57, 12, p. 2546-54 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    The mitogenic effect of Gas6 on pancreatic beta cells is mediated via the receptor tyrosine kinase Axl

    Haase, T. N., Gustafsson, A., Nalla, A., Ringholm, L., Damm, Peter, Mathiesen, Elisabeth, Dahlback, B., Billestrup, Nils & Nielsen, Jens Høiriis, Sep 2014, In: Diabetologia. 57, 1 Suppl, p. S173-S174 408.

    Research output: Contribution to journalConference abstract in journalpeer-review

  36. Published

    Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection

    Christensen, D. P., Gysemans, C., Lundh, M., Dahllöf, M. S., Noesgaard, D., Schmidt, S. F., Mandrup, S., Birkbak, N., Workman, C., Piemonti, L., Blaabjerg, L., Monzani, V., Fossati, G., Mascagni, P., Paraskevas, S., Aikin, R. A., Billestrup, N., Grunnet, L. G., Dinarello, C. A., Mathieu, C. & 1 others, Mandrup-Poulsen, Thomas, 6 Jan 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1055-9 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis

    Prause, Michala Cecilie Burstein, Christensen, D. P., Billestrup, Nils & Mandrup-Poulsen, Thomas, 2014, In: PLOS ONE. 9, 1, p. 1-11 11 p., e87067.

    Research output: Contribution to journalJournal articlepeer-review

  38. 2013
  39. Published

    Growth arrest specific protein (GAS) 6: a role in the regulation of proliferation and functional capacity of the perinatal rat beta cell

    Haase, T. N., Rasmussen, M., Jaksch, C. A. M., Gaarn, L. W., Petersen, C. K., Billestrup, Nils & Nielsen, Jens Høiriis, Apr 2013, In: Diabetologia. 56, 4, p. 763-773 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. 2012
  41. Published

    Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic ß cell fate in response to cytokines

    Hansen, J. B., Tonnesen, M. F., Madsen, A. N., Hagedorn, P., Friberg, J., Grunnet, L. G., Heller, R. S., Nielsen, A. Ø., Størling, J., Baeyens, L., Anker-Kitai, L., Qvortrup, K., Bouwens, L., Efrat, S., Aalund, M., Andrews, N. C., Billestrup, N., Karlsen, A. E., Holst, B., Pociot, F. & 1 others, Mandrup-Poulsen, Thomas, 2012, In: Cell Metabolism. 16, 4, p. 449-61 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. 2011
  43. Published

    ID'ing a novel inhibitor of β-cell function, Id1

    Billestrup, Nils, Oct 2011, In: Diabetes. 60, 10, p. 2455-6 2 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    ß-cell specific overexpression of suppressor of cytokine signalling-3 does not protect against multiple low dose streptozotocin induced type 1 diabetes in mice

    Börjesson, A., Rønn, S. G., Karlsen, A. E., Billestrup, Nils & Sandler, S., 30 Apr 2011, In: Immunology Letters. 136, 1, p. 74-9 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Direct demonstration of NCAM cis-dimerization and inhibitory effect of palmitoylation using the BRET2 technique

    Kulahin, N., Grunnet, L. G., Lundh, M., Christensen, D. P., Jorgensen, R., Heding, A., Billestrup, Nils, Berezin, V., Bock, E. & Mandrup-Poulsen, Thomas, 3 Jan 2011, In: FEBS Letters. 585, 1, p. 58-64 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Endothelial Progenitor Cells in Long-Standing Asymptomatic Type 1 Diabetic Patients with or without Diabetic Nephropathy

    Reinhard, H., Jacobsen, P. K., Lajer, M., Tarnow, L., Astrup, A. S., Kim, W. Y., Pedersen, N., Billestrup, Nils, Mandrup-Poulsen, Thomas, Parving, H. & Rossing, Peter, 2011, In: Nephron Clinical Practice. 118, 3, p. c309-c314 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus

    Christensen, D. P., Dahllöf, M. S., Lundh, M., Rasmussen, D. N., Nielsen, M. D., Billestrup, Nils, Grunnet, L. G. & Mandrup-Poulsen, Thomas, 2011, In: Molecular Medicine. 17, 5-6, p. 378-90 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  48. 2010
  49. Published

    Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines

    Lundh, M., Christensen, D. P., Rasmussen, D. N., Mascagni, P., Dinarello, C. A., Billestrup, Nils, Grunnet, L. G. & Mandrup-Poulsen, Thomas, 1 Dec 2010, In: Diabetologia. 53, 12, p. 2569-78 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes

    Reinhard, H., Jacobsen, P. K., Lajer, M., Pedersen, N., Billestrup, Nils, Mandrup-Poulsen, Thomas, Parving, H. & Rossing, Peter, 1 Oct 2010, In: Diabetologica. 53, 10, p. 2129-33 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Deficient SOCS3 and SHP-1 Expression in Psoriatic T Cells

    Eriksen, K. W., Woetmann, Anders , Skov, Lone, Krejsgaard, T., Bovin, L. F., Hansen, M. L., Grønbæk, Kirsten, Billestrup, Nils, Nissen, Mogens Holst, Geisler, Carsten, Wasik, M. A. & Ødum, Niels, 2010, In: Journal of Investigative Dermatology. 130, 6, p. 1590-7 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    Dissociation between skeletal muscle inhibitor-{kappa}B kinase/nuclear factor-{kappa}B pathway activity and insulin sensitivity in nondiabetic twins

    Friedrichsen, M., Ribel-Madsen, R., Wojtaszewski, Jørgen F P, Grunnet, L., Richter, Erik A., Billestrup, Nils, Ploug, Thorkil, Vaag, A. & Poulsen, P., 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 1, p. 414-421 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  53. Accepted/In press

    Genetic deficiency of tissue inhibitor of metalloproteinase (TIMP) 1 does not affect apoptosis in cytokine-exposed mouse islets in vitro.

    Hansen, J. B., Tonnesen, M. F., Rømer, M. U. K., Billestrup, Nils, Brunner, N. & Mandrup-Poulsen, Thomas, 2010, (Accepted/In press).

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  54. 2009
  55. Published

    Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells

    Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, Nils, Eizirik, D. L., Størling, J. & Mandrup-Poulsen, Thomas, Sep 2009, In: Endocrinology. 150, 9, p. 4094-103 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    CRFR1 is expressed on pancreatic beta cells, promotes beta cell proliferation, and potentiates insulin secretion in a glucose-dependent manner

    Huising, M. O., van der Meulen, T., Vaughan, J. M., Matsumoto, M., Donaldson, C. J., Park, H., Billestrup, Nils & Vale, W. W., 2009, In: Proceedings of the National Academy of Science of the United States of America. 107, 2, p. 912-7 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  57. Published

    IL-1 beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells

    Jacobsen, M. L. B., Ronn, S. G., Bruun, C., Larsen, C. M., Eizirik, D. L., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2009, In: Diabetologia. 52, 2, p. 281-288 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  58. Published

    Inhibition of Nuclear Factor-kappa B or Bax Prevents Endoplasmic Reticulum Stress-But Not Nitric Oxide-Mediated Apoptosis in INS-1E Cells

    Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, Nils, Eizirik, D. L., Storling, J. & Mandrup-Poulsen, Thomas, 2009, In: Endocrinology. 150, 9, p. 4094-4103 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  59. Published

    Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells

    Grunnet, L. G., Aikin, R., Tonnesen, M. F., Paraskevas, S., Blaabjerg, L., Størling, J., Rosenberg, L., Billestrup, Nils, Maysinger, D. & Mandrup-Poulsen, Thomas, 2009, In: Diabetes. 58, 8, p. 1807-15 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  60. Published

    Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells

    Bruun, C., Heding, P. E., Rønn, S. G., Frobøse, H., Rhodes, C. J., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2009, In: Molecular and Cellular Endocrinology. 311, 1-2, p. 32-8 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  61. Published

    The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

    Collombat, P., Xu, X., Ravassard, P., Sosa-Pineda, B., Dussaud, S., Billestrup, Nils, Madsen, O. D., Serup, P., Heimberg, H. & Mansouri, A., 2009, In: Cell. 138, 3, p. 449-62 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  62. 2008
  63. Published

    Dedifferentiation for replication of human beta-cells: a division between mice and men?

    Billestrup, Nils & Otonkoski, T., 2008, In: Diabetes. 57, 6, p. 1457-8 2 p.

    Research output: Contribution to journalJournal articlepeer-review

  64. Published

    IL-1beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells

    Jacobsen, M. L. B., Rønn, S. G., Bruun, C., Larsen, C. M., Eizirik, D. L., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2008, In: Diabetologia. 52, 2, p. 281-8 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  65. Published

    Impact of fasting on growth hormone signaling and action in muscle and fat

    Moller, L., Dalman, L., Norrelund, H., Billestrup, Nils, Frystyk, J., Moller, N. & Jorgensen, J. O. L., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 3, p. 965-72 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  66. Published

    Proliferation of sorted human and rat beta cells

    Parnaud, G., Bosco, D., Berney, T., Pattou, F., Kerr-Conte, J., Donath, M. Y., Bruun, C., Mandrup-Poulsen, Thomas, Billestrup, Nils & Halban, P. A., 2008, In: Diabetologia. 51, 1, p. 91-100 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  67. Published

    Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection

    Rønn, S. G., Börjesson, A., Bruun, C., Heding, P. E., Frobøse, H., Mandrup-Poulsen, Thomas, Karlsen, A. E., Rasschaert, J., Sandler, S. & Billestrup, Nils, 2008, In: Diabetologia. 51, 10, p. 1873-1882 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  68. 2007
  69. Published

    Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

    Larsen, L., Tonnesen, M., Ronn, S. G., Størling, J., Jørgensen, S., Mascagni, P., Dinarello, C. A., Billestrup, Nils & Mandrup-Poulsen, Thomas, Apr 2007, In: Diabetologia. 50, 4, p. 779-89 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  70. Published

    Effects of growth hormone on glucose and fat metabolism in human subjects

    Jørgensen, J. O. L., Møller, L., Krag, M. B., Billestrup, Nils & Christiansen, J. K. S., 1 Mar 2007, In: Endocrinology & Metabolism Clinics of North America. 36, 1, p. 75-87 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  71. 2006
  72. Published

    GH receptor signaling in skeletal muscle and adipose tissue in human subjects following exposure to an intravenous GH bolus

    Jørgensen, J. O. L., Jessen, N., Pedersen, S. B., Vestergaard, E. T., Gormsen, L. C., Lund, S. & Billestrup, Nils, 1 Nov 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 5, p. E899-905

    Research output: Contribution to journalJournal articlepeer-review

  73. Published

    Growth arrest- and DNA-damage-inducible 45beta gene inhibits c-Jun N-terminal kinase and extracellular signal-regulated kinase and decreases IL-1beta-induced apoptosis in insulin-producing INS-1E cells

    Larsen, C. M., Døssing, M. G., Papa, S., Franzoso, G., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 May 2006, In: Diabetologia. 49, 5, p. 980-9 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  74. Published

    IL-1beta-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line

    Petersen, L. G., Størling, J., Heding, P., Li, S., Berezin, V., Saldeen, J., Billestrup, Nils, Bock, E. & Mandrup-Poulsen, Thomas, 2006, In: Diabetologia. 49, 8, p. 1864-75 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  75. 2005
  76. Published

    Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells

    Larsen, L., Størling, J., Darville, M., Eizirik, D. L., Bonny, C., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 Dec 2005, In: Diabetologia. 48, 12, p. 2582-90 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  77. Published

    Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt

    Størling, J., Binzer, J., Andersson, A., Züllig, R. A., Tonnesen, M., Knudsen, R. L. P., Spinas, G. A., Sandler, S., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 Oct 2005, In: Diabetologia. 48, 10, p. 2039-50 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  78. Published

    Regulation of pancreatic beta-cell mass and proliferation by SOCS-3

    Lindberg, K., Rønn, S. G., Tornehave, D., Richter, H., Hansen, J. A., Rømer, J., Jackerott, M. & Billestrup, Nils, Oct 2005, In: Journal of Molecular Endocrinology. 35, 2, p. 231-43 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  79. Published

    Mechanism of protein tyrosine phosphatase 1B-mediated inhibition of leptin signalling

    Lund, I. K., Hansen, J. A., Andersen, H. S., Møller, N. P. H. & Billestrup, Nils, 1 Apr 2005, In: Journal of Molecular Endocrinology. 34, 2, p. 339-51 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  80. 2004
  81. Published

    Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1beta-mediated toxicity through inhibition of multiple nuclear factor-kappaB-regulated proapoptotic pathways

    Karlsen, A. E., Heding, P. E., Frobøse, H., Rønn, S. G., Kruhøffer, M., Orntoft, T. F., Darville, M., Eizirik, D. L., Pociot, Flemming, Nerup, J., Mandrup-Poulsen, Thomas & Billestrup, Nils, 1 Nov 2004, In: Diabetologia. 47, 11, p. 1998-2011 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  82. Published

    Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity

    Gylvin, T., Nolsøe, R., Hansen, Torben, Nielsen, E. M. D., Bergholdt, R., Karlsen, A. E., Billestrup, Nils, Borch-Johnsen, K., Pedersen, O., Mandrup-Poulsen, Thomas, Nerup, J. & Pociot, Flemming, 1 Jul 2004, In: Diabetologia. 47, 7, p. 1273-7 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  83. Published

    Growth hormone receptor expression and function in pituitary adenomas

    Clausen, L. R., Kristiansen, M. T., Rasmussen, L. M., Billestrup, Nils, Blaabjerg, O., Ledet, T. & Jørgensen, J. O. L., May 2004, In: Clinical Endocrinology. 60, 5, p. 576-83 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  84. 2003
  85. Published

    Nuclear translocation and retention of growth hormone

    Mertani, H. C., Raccurt, M., Abbate, A., Kindblom, J., Törnell, J., Billestrup, Nils, Usson, Y., Morel, G. & Lobie, P. E., Jul 2003, In: Endocrinology. 144, 7, p. 3182-95 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  86. Published

    Signal transducer and activator of transcription 5 activation is sufficient to drive transcriptional induction of cyclin D2 gene and proliferation of rat pancreatic beta-cells

    Friedrichsen, B. N., Richter, H. E., Hansen, J. A., Rhodes, C. J., Nielsen, Jens Høiriis, Billestrup, Nils & Møldrup, A., May 2003, In: Molecular endocrinology (Baltimore, Md.). 17, 5, p. 945-58 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  87. Published

    The role of signal transducer and activator of transcription 5 in the inhibitory effects of GH on adipocyte differentiation

    Richter, H. E., Albrektsen, T. & Billestrup, Nils, Apr 2003, In: Journal of Molecular Endocrinology. 30, 2, p. 139-50 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  88. Published

    SOCS-3 is involved in the downregulation of the acute insulin-like effects of growth hormone in rat adipocytes by inhibition of Jak2/IRS-1 signaling

    Ridderstråle, M., Amstrup, J., Hilton, D. J., Billestrup, Nils & Tornqvist, H., Mar 2003, In: Hormone and Metabolic Research. Supplement. 35, 3, p. 169-77 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  89. 2002
  90. Published

    Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling

    Greenhalgh, C. J., Metcalf, D., Thaus, A. L., Corbin, J. E., Uren, R., Morgan, P. O., Fabri, L. J., Zhang, J., Martin, H. M., Willson, T. A., Billestrup, Nils, Nicola, N. A., Baca, M., Alexander, W. S. & Hilton, D. J., 25 Oct 2002, In: The Journal of Biological Chemistry. 277, 43, p. 40181-4 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  91. Published

    The effect of suppressor of cytokine signaling 3 on GH signaling in beta-cells

    Rønn, S. G., Hansen, J. A., Lindberg, K., Karlsen, A. E. & Billestrup, Nils, Sep 2002, In: Molecular endocrinology (Baltimore, Md.). 16, 9, p. 2124-34 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  92. 2000
  93. Published

    Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B

    Stofega, M. R., Herrington, J., Billestrup, Nils & Carter-Su, C., Sep 2000, In: Molecular endocrinology (Baltimore, Md.). 14, 9, p. 1338-50 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  94. Published

    Growth hormone (GH)-independent dimerization of GH receptor by a leucine zipper results in constitutive activation

    Behncken, S. N., Billestrup, Nils, Brown, R., Amstrup, J., Conway-Campbell, B. & Waters, M. J., 2 Jun 2000, In: The Journal of Biological Chemistry. 275, 22, p. 17000-7 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  95. 1999
  96. Published

    Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins

    Hansen, J. A., Lindberg, K., Hilton, D. J., Nielsen, Jens Høiriis & Billestrup, Nils, Nov 1999, In: Molecular endocrinology (Baltimore, Md.). 13, 11, p. 1832-43 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  97. Published

    Developmental expression of proprotein convertase 1/3 in the rat

    Lee, Y. C., Damholt, A. B., Billestrup, Nils, Kisbye, T., Galante, P., Michelsen, B., Kofod, H. & Nielsen, Jens Høiriis, 10 Sep 1999, In: Molecular and Cellular Endocrinology. 155, 1-2, p. 27-35 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  98. Published

    Beta cell proliferation and growth factors

    Nielsen, Jens Høiriis, Svensson, C., Møldrup, A., Galsgaard, E. D. & Billestrup, Nils, Jan 1999, In: Journal of Molecular Medicine. 77, 1, p. 62-6 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  99. 1998
  100. Published

    Characterization of the inhibitory effect of growth hormone on primary preadipocyte differentiation

    Hansen, L. H., Madsen, B., Teisner, B., Nielsen, Jens Høiriis & Billestrup, Nils, Aug 1998, In: Molecular endocrinology (Baltimore, Md.). 12, 8, p. 1140-9 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  101. Published

    Molecular mechanism of growth hormone signalling

    Billestrup, Nils, Hansen, J. A., Hansen, L. H., Møldrup, A., Galsgaard, E. D. & Nielsen, Jens Høiriis, Apr 1998, In: Endocrine Journal. 45 Suppl, p. S41-5

    Research output: Contribution to journalJournal articlepeer-review

  102. Published

    Regulation of glucose transport and c-fos and egr-1 expression in cells with mutated or endogenous growth hormone receptors

    Gong, T. W., Meyer, D. J., Liao, J., Hodge, C. L., Campbell, G. S., Wang, X., Billestrup, Nils, Carter-Su, C. & Schwartz, J., Apr 1998, In: Endocrinology. 139, 4, p. 1863-71 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  103. Published

    Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling

    Adams, T. E., Hansen, J. A., Starr, R., Nicola, N. A., Hilton, D. J. & Billestrup, Nils, 16 Jan 1998, In: The Journal of Biological Chemistry. 273, 3, p. 1285-7 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  104. 1997
  105. Published

    Growth hormone and prolactin stimulate the expression of rat preadipocyte factor-1/delta-like protein in pancreatic islets: molecular cloning and expression pattern during development and growth of the endocrine pancreas

    Carlsson, C., Tornehave, D., Lindberg, K., Galante, P., Billestrup, Nils, Michelsen, B., Larsson, L. I. & Nielsen, Jens Høiriis, Sep 1997, In: Endocrinology. 138, 9, p. 3940-8 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  106. Published

    The role of GH receptor tyrosine phosphorylation in Stat5 activation

    Hansen, J. A., Hansen, Lars Hestbjerg, Wang, X., Kopchick, J. J., Gouilleux, F., Groner, B., Møldrup, A., Galsgaard, E. D., Nielsen, Jens Høiriis & Billestrup, Nils, Jun 1997, In: Journal of Molecular Endocrinology. 18, 3, p. 213-21 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  107. 1996
  108. Published

    Growth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling

    Argetsinger, L. S., Norstedt, G., Billestrup, Nils, White, M. F. & Carter-Su, C., 15 Nov 1996, In: The Journal of Biological Chemistry. 271, 46, p. 29415-21 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  109. Published

    Distinct cytoplasmic domains of the growth hormone receptor are required for glucocorticoid- and phorbol ester-induced decreases in growth hormone (GH) binding. These domains are different from that reported for GH-induced receptor internalization

    King, A. P., Tseng, M. J., Logsdon, C. D., Billestrup, Nils & Carter-Su, C., 26 Jul 1996, In: The Journal of Biological Chemistry. 271, 30, p. 18088-94 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  110. Published

    Identification of a growth hormone-responsive STAT5-binding element in the rat insulin 1 gene

    Galsgaard, E. D., Gouilleux, F., Groner, B., Serup, Palle, Billestrup, Nils & Nielsen, Jens Høiriis, Jun 1996, In: Molecular endocrinology (Baltimore, Md.). 10, 6, p. 652-60 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  111. Published

    Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation

    Hansen, L. H., Wang, X., Kopchick, J. J., Bouchelouche, P., Galsgaard, E. D., Nielsen, Jens Høiriis & Billestrup, Nils, 24 May 1996, In: The Journal of Biological Chemistry. 271, 21, p. 12669-73 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  112. Published

    The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH

    Smit, L. S., Meyer, D. J., Billestrup, Nils, Norstedt, G., Schwartz, J. & Carter-Su, C., May 1996, In: Molecular endocrinology (Baltimore, Md.). 10, 5, p. 519-33 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  113. 1995
  114. Published

    Growth hormone-dependent phosphorylation of tyrosine 333 and/or 338 of the growth hormone receptor

    VanderKuur, J. A., Wang, X., Zhang, L., Allevato, G., Billestrup, Nils & Carter-Su, C., 15 Sep 1995, In: The Journal of Biological Chemistry. 270, 37, p. 21738-44 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  115. Published

    Requirement of tyrosine residues 333 and 338 of the growth hormone (GH) receptor for selected GH-stimulated function

    Lobie, P. E., Allevato, G., Norstedt, G., Billestrup, Nils & Nielsen, Jens Høiriis, 15 Sep 1995, In: The Journal of Biological Chemistry. 270, 37, p. 21745-50 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  116. Published

    Molecular dissection of the growth hormone receptor. Identification of distinct cytoplasmic domains corresponding to different signaling pathways

    Billestrup, Nils, Allevato, G., Møldrup, A., Galsgaard, E. D., Amstrup, J., Hansen, J. A., Svensson, C. & Nielsen, Jens Høiriis, 7 Sep 1995, In: Annals of the New York Academy of Sciences. 766, p. 481-3 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  117. Published

    Identification of phenylalanine 346 in the rat growth hormone receptor as being critical for ligand-mediated internalization and down-regulation

    Allevato, G., Billestrup, Nils, Goujon, L., Galsgaard, E. D., Norstedt, G., Postel-Vinay, M. C., Kelly, P. A. & Nielsen, Jens Høiriis, 21 Jul 1995, In: The Journal of Biological Chemistry. 270, 29, p. 17210-4 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  118. Published

    Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1

    Argetsinger, L. S., Hsu, G. W., Myers, M. G., Billestrup, Nils, White, M. F. & Carter-Su, C., 16 Jun 1995, In: The Journal of Biological Chemistry. 270, 24, p. 14685-92 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  119. Published

    Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2

    VanderKuur, J., Allevato, G., Billestrup, Nils, Norstedt, G. & Carter-Su, C., 31 Mar 1995, In: The Journal of Biological Chemistry. 270, 13, p. 7587-93 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  120. Published

    Growth hormone receptor C-terminal domains required for growth hormone-induced intracellular free Ca2+ oscillations and gene transcription

    Billestrup, Nils, Bouchelouche, P., Allevato, G., Ilondo, M. & Nielsen, Jens Høiriis, 28 Mar 1995, In: Proceedings of the National Academy of Sciences of the United States of America. 92, 7, p. 2725-9 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  121. 1994
  122. Published

    The cellular mechanism of growth hormone signal transduction

    Lobie, P. E., Wood, T. J., Sliva, D., Billestrup, Nils, Waters, M. J., Enberg, B. & Norstedt, G., Dec 1994, In: Acta Paediatrica. Supplement. 406, p. 39-46; discussion 47

    Research output: Contribution to journalJournal articlepeer-review

  123. Published

    Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase

    VanderKuur, J. A., Wang, X., Zhang, L., Campbell, G. S., Allevato, G., Billestrup, Nils, Norstedt, G. & Carter-Su, C., 26 Aug 1994, In: The Journal of Biological Chemistry. 269, 34, p. 21709-17 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  124. Published

    Cell transfection as a tool to study growth hormone action

    Norstedt, G., Enberg, B., Francis, S., Hansson, A., Hulthén, A., Lobie, P. E., Sliva, D., Wood, T. J. & Billestrup, Nils, Jul 1994, In: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 206, 3, p. 181-4 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  125. Published

    Identification of intracellular domains in the growth hormone receptor involved in signal transduction

    Billestrup, Nils, Allevato, G., Norstedt, G., Møldrup, A. & Nielsen, Jens Høiriis, Jul 1994, In: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 206, 3, p. 205-9 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  126. 1993
  127. Published

    Growth of the endocrine pancreas: the role of somatolactogenic hormones and receptors

    Billestrup, Nils, Møldrup, A., Allevato, G., Petersen, Erik Brinch, Pedersen, Johan, Hansen, J. A. & Nielsen, Jens Høiriis, Feb 1993, In: Biochemical Society Transactions. 21, 1, p. 146-9 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  128. 1992
  129. Published

    Pituitary adenomas in mice transgenic for growth hormone-releasing hormone

    Asa, S. L., Kovacs, K., Stefaneanu, L., Horvath, E., Billestrup, Nils, Gonzalez-Manchon, C. & Vale, W., Nov 1992, In: Endocrinology. 131, 5, p. 2083-9 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  130. Published

    Evidence for association of the cloned liver growth hormone receptor with a tyrosine kinase

    Wang, X., Uhler, M. D., Billestrup, Nils, Norstedt, G., Talamantes, F., Nielsen, Jens Høiriis & Carter-Su, C., 25 Aug 1992, In: The Journal of Biological Chemistry. 267, 24, p. 17390-6 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  131. Published

    The role of growth hormone and prolactin in beta cell growth and regeneration

    Nielsen, Jens Høiriis, Møldrup, A., Billestrup, Nils, Petersen, E. D., Allevato, G. & Stahl, M., 1992, Pancreatic islet cell regeneration and growth. Vol. 321. p. 9-17; discussion 19-20 (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  132. 1991
  133. Published

    Growth hormone action in rat insulinoma cells expressing truncated growth hormone receptors

    Møldrup, A., Allevato, G., Dyrberg, T., Billestrup, Nils & Nielsen, Jens Høiriis, 15 Sep 1991, In: The Journal of Biological Chemistry. 266, 26, p. 17441-5 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  134. Published

    The stimulatory effect of growth hormone, prolactin, and placental lactogen on beta-cell proliferation is not mediated by insulin-like growth factor-I

    Billestrup, Nils & Nielsen, Jens Høiriis, Aug 1991, In: Endocrinology. 129, 2, p. 883-8 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  135. 1990
  136. Published

    Introduction of exogenous growth hormone receptors augments growth hormone-responsive insulin biosynthesis in rat insulinoma cells

    Billestrup, Nils, Møldrup, A., Serup, Palle, Mathews, L. S., Norstedt, G. & Nielsen, Jens Høiriis, Sep 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 18, p. 7210-4 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  137. Published

    Rat insulinoma cells express both a 115-kDa growth hormone receptor and a 95-kDa prolactin receptor structurally related to the hepatic receptors

    Møldrup, A., Billestrup, Nils & Nielsen, Jens Høiriis, 25 May 1990, In: The Journal of Biological Chemistry. 265, 15, p. 8686-90 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  138. Published

    Pituitary mammosomatotroph adenomas develop in old mice transgenic for growth hormone-releasing hormone

    Asa, S. L., Kovacs, K., Stefaneanu, L., Horvath, E., Billestrup, Nils, Gonzalez-Manchon, C. & Vale, W., Mar 1990, In: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 193, 3, p. 232-5 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  139. Published

    Inhibition of somatotroph growth and growth hormone biosynthesis by activin in vitro

    Billestrup, Nils, González-Manchón, C., Potter, E. & Vale, W., Feb 1990, In: Molecular endocrinology (Baltimore, Md.). 4, 2, p. 356-62 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  140. Published

    Effect of growth hormone and serum on the expression of the proto-oncogenes c-jun and c-fos in insulin producing cells

    Petersen, E. D., Billestrup, Nils & Nielsen, Jens Høiriis, 1990, In: Biomedica Biochimica Acta. 49, 12, p. 1171-5 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  141. Published

    Expression of the growth hormone receptor gene in insulin producing cells

    Møldrup, A., Billestrup, Nils & Nielsen, Jens Høiriis, 1990, In: Biomedica Biochimica Acta. 49, 12, p. 1151-5 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  142. 1989
  143. Published

    Adenohypophysial changes in mice transgenic for human growth hormone-releasing factor: a histological, immunocytochemical, and electron microscopic investigation

    Stefaneanu, L., Kovacs, K., Horvath, E., Asa, S. L., Losinski, N. E., Billestrup, Nils, Price, J. & Vale, W., Nov 1989, In: Endocrinology. 125, 5, p. 2710-8 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  144. Published

    Multiple growth hormone-binding proteins are expressed on insulin-producing cells

    Møldrup, A., Billestrup, Nils, Thorn, N. A., Lernmark, A. & Nielsen, Jens Høiriis, Aug 1989, In: Molecular endocrinology (Baltimore, Md.). 3, 8, p. 1173-82 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  145. Published

    Growth hormone is a growth factor for the differentiated pancreatic beta-cell

    Linde, S., Welinder, B. S., Billestrup, Nils, Madsen, O. D. & Nielsen, Jens Høiriis, Jan 1989, In: Molecular endocrinology (Baltimore, Md.). 3, 1, p. 165-73 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  146. 1987
  147. Published

    Identification and characterization of a pituitary corticotropin-releasing factor binding protein by chemical cross-linking

    Nishimura, E., Billestrup, Nils, Perrin, M. & Vale, W., 25 Sep 1987, In: The Journal of Biological Chemistry. 262, 27, p. 12893-6 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  148. Published

    Growth hormone-releasing factor induces c-fos expression in cultured primary pituitary cells

    Billestrup, Nils, Mitchell, R. L., Vale, W. & Verma, I. M., Apr 1987, In: Molecular endocrinology (Baltimore, Md.). 1, 4, p. 300-5 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  149. 1986
  150. Published

    Identification of corticotropin-releasing factor (CRF) target cells and effects of dexamethasone on binding in anterior pituitary using a fluorescent analog of CRF

    Schwartz, J., Billestrup, Nils, Perrin, M., Rivier, J. & Vale, W., Nov 1986, In: Endocrinology. 119, 5, p. 2376-82 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  151. Published

    Growth hormone-releasing factor stimulates proliferation of somatotrophs in vitro

    Billestrup, Nils, Swanson, L. W. & Vale, W., Sep 1986, In: Proceedings of the National Academy of Sciences of the United States of America. 83, 18, p. 6854-7 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  152. 1985
  153. Published

    Growth hormone binding to specific receptors stimulates growth and function of cloned insulin-producing rat insulinoma RIN-5AH cells

    Billestrup, Nils & Martin, J. M., Mar 1985, In: Endocrinology. 116, 3, p. 1175-81 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  154. Published

    Human growth hormone binding and stimulation of insulin biosynthesis in cloned rat insulinoma cells

    Billestrup, Nils, 1985, In: Biomedica Biochimica Acta. 44, 1, p. 85-7 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  155. 1984
  156. Published

    Preparation of 125I-protein A usable for up to 10 months in immunoassays

    Dyrberg, T. & Billestrup, Nils, 6 Jul 1984, In: Journal of Immunological Methods. 71, 2, p. 193-201 9 p.

    Research output: Contribution to journalJournal articlepeer-review

ID: 15311848