Nils Billestrup

Nils Billestrup

Professor


  1. 2024
  2. Published

    Butyrate functions as a histone deacetylase inhibitor to protect pancreatic beta cells from IL-1β-induced dysfunction

    Pedersen, Signe Schultz, Ingerslev, Lars Roed, Olsen, M., Prause, Michala Cecilie Burstein & Billestrup, Nils, 2024, In: FEBS Journal. 291, 3, p. 566-583

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding

    Urizar, A. I., Prause, Michala Cecilie Burstein, Ingerslev, L. R., Wortham, M., Sui, Y., Sander, M., Williams, K., Barrès, Romain, Larsen, M. R., Christensen, G. L. & Billestrup, Nils, 2023, In: Cell Death and Disease. 14, 7, 16 p., 399.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice

    Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Sørensen, C., Størling, Joachim, Moritz, Thomas, Mariño, E. & Billestrup, Nils, 2023, In: International Journal of Molecular Sciences. 24, 5, 17 p., 4533.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2022
  7. Published

    Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells

    Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Williams, K., Barrès, Romain & Billestrup, Nils, 2022, In: Journal of Biological Chemistry. 298, 9, 14 p., 102312.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2021
  9. Published

    Butyrate protects pancreatic beta cells from cytokine-induced dysfunction

    Prause, Michala Cecilie Burstein, Pedersen, Signe Schultz, Tsonkova, V., Qiao, M. & Billestrup, Nils, 2021, In: International Journal of Molecular Sciences. 22, 19, 18 p., 10427.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2019
  11. Published

    Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1 beta is associated with changes in expression of beta-cell maturity genes and associated histone modifications

    Urizar, A. I., Prause, Michala Cecilie Burstein, Wortham, M., Sui, Y., Thams, P., Sander, M., Christensen, G. L. & Billestrup, Nils, 2019, In: Molecular and Cellular Endocrinology. 496, 12 p., 110524 .

    Research output: Contribution to journalReviewResearchpeer-review

  12. 2018
  13. Published

    Characterization of the Molecular Mechanisms Underlying Glucose Stimulated Insulin Secretion from Isolated Pancreatic β-cells Using Post-translational Modification Specific Proteomics (PTMomics)

    Kang, T., Jensen, P., Huang, H., Lund Christensen, G., Billestrup, Nils & Larsen, M. R., Jan 2018, In: Molecular and Cellular Proteomics. 17, 1, p. 95-110 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2017
  15. Published

    In-vitro and in-vivo studies supporting the therapeutic potential of ZP3022 in diabetes

    Skarbaliene, J., Rigbolt, K. T., Fosgerau, K. & Billestrup, Nils, 15 Nov 2017, In: European Journal of Pharmacology. 815, p. 181-189 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo

    Berchtold, L. A., Miani, M., Diep, T. A., Madsen, A. N., Cigliola, V., Colli, M., Miskovic Krivokapic, Jelena, Pociot, Flemming, Eizirik, D. L., Meda, P., Holst, Birgitte, Billestrup, Nils & Storling, J., 2017, In: Molecular and Cellular Endocrinology. 448, p. 108-121 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2016
  18. Published

    Regulation of Pancreatic Alpha Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) in vitro.

    Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p., 27479530 .

    Research output: Contribution to journalJournal articleResearchpeer-review

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