Michael Jonathan Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3, 2200 København N, 12.6, Building: 30
- 2007
Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides. / Dremina, Elena S; Sharov, Victor S; Davies, Michael Jonathan; Schöneich, Christian.
In: Chemical Research in Toxicology, Vol. 20, No. 10, 10.2007, p. 1462-9.Research output: Contribution to journal › Journal article › Research › peer-review
Hypochlorous acid-mediated protein oxidation : how important are chloramine transfer reactions and protein tertiary structure? / Pattison, David I; Hawkins, Clare Louise; Davies, Michael Jonathan.
In: Biochemistry, Vol. 46, No. 34, 28.08.2007, p. 9853-64.Research output: Contribution to journal › Journal article › Research › peer-review
Reversible binding of kynurenine to lens proteins : potential protection by glutathione in young lenses. / Parker, Nicole R; Korlimbinis, Anastasia; Jamie, Joanne F; Davies, Michael Jonathan; Truscott, Roger J W.
In: Investigative Ophthalmology & Visual Science, Vol. 48, No. 8, 08.2007, p. 3705-13.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A randomized controlled trial examining combinations of repaglinide, metformin and NPH insulin. / Davies, M. J.; Thaware, P. K.; Tringham, J. R.; Howe, J.; Jarvis, J.; Johnston, V.; Kitchener, D. L.; Skinner, T. C.; McNally, P. G.; Lawrence, I. G.
In: Diabetic Medicine, Vol. 24, No. 7, 01.07.2007, p. 714-719.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides : potential modulation of cell signaling by protein oxidation products. / Gracanin, Michelle; Davies, Michael Jonathan.
In: Free Radical Biology & Medicine, Vol. 42, No. 10, 15.05.2007, p. 1543-51.Research output: Contribution to journal › Journal article › Research › peer-review
Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid : evidence for a hydroxyl-radical-like mechanism. / Kennett, Eleanor C; Davies, Michael Jonathan.
In: Free Radical Biology & Medicine, Vol. 42, No. 8, 15.04.2007, p. 1278-89.Research output: Contribution to journal › Journal article › Research › peer-review
Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro. / Rashid, Imran; van Reyk, David M; Davies, Michael Jonathan.
In: FEBS letters, Vol. 581, No. 5, 06.03.2007, p. 1067-70.Research output: Contribution to journal › Journal article › Research › peer-review
Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages. / Brown, Bronwyn E; Rashid, Imran; van Reyk, David M; Davies, Michael Jonathan.
In: F E B S Journal, Vol. 274, No. 6, 03.2007, p. 1530-41.Research output: Contribution to journal › Journal article › Research › peer-review
Degradation of extracellular matrix and its components by hypobromous acid. / Rees, Martin D; McNiven, Tane N; Davies, Michael Jonathan.
In: Biochemical Journal, Vol. 401, No. 2, 15.01.2007, p. 587-96.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Diabetes education and self-management for ongoing and newly diagnosed (DESMOND) : Process modelling of pilot study. / Skinner, T. Chas; Carey, Marian E.; Cradock, Sue; Daly, Heather; Davies, Melanie J.; Doherty, Yvonne; Heller, Simon; Khunti, Kamlesh; Oliver, Lindsay.
In: Patient Education and Counseling, Vol. 64, No. 1-3, 01.12.2006, p. 369-377.Research output: Contribution to journal › Journal article › Research › peer-review
Protein and low molecular mass thiols as targets and inhibitors of glycation reactions. / Zeng, Jingmin; Davies, Michael Jonathan.
In: Chemical Research in Toxicology, Vol. 19, No. 12, 12.2006, p. 1668-76.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols. / Zeng, Jingmin; Dunlop, Rachael A; Rodgers, Kenneth J; Davies, Michael Jonathan.
In: Biochemical Journal, Vol. 398, No. 2, 01.09.2006, p. 197-206.Research output: Contribution to journal › Journal article › Research › peer-review
Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals. / Wood, Geoffrey P F; Easton, Christopher J; Rauk, Arvi; Davies, Michael Jonathan; Radom, Leo.
In: Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, Vol. 110, No. 34, 31.08.2006, p. 10316-23.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines : implications for the prevention of hypochlorous-acid-mediated damage. / Pattison, David I; Davies, Michael Jonathan.
In: Biochemistry, Vol. 45, No. 26, 04.07.2006, p. 8152-62.Research output: Contribution to journal › Journal article › Research › peer-review
Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions. / Stanley, Naomi; Stadler, Nadina; Bannon, Paul G; Woods, Alan A; Davies, Michael Jonathan.
In: Free Radical Biology & Medicine, Vol. 40, No. 9, 01.05.2006, p. 1636-43.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides. / Headlam, Henrietta A; Gracanin, Michelle; Rodgers, Kenneth J; Davies, Michael Jonathan.
In: Free Radical Biology & Medicine, Vol. 40, No. 9, 01.05.2006, p. 1539-48.Research output: Contribution to journal › Journal article › Research › peer-review
Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid. / Malle, Ernst; Marsche, Gunther; Arnhold, Jürgen; Davies, Michael Jonathan.
In: B B A - Reviews on Cancer, Vol. 1761, No. 4, 04.2006, p. 392-415.Research output: Contribution to journal › Journal article › Research › peer-review
Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives. / Rees, Martin D; Davies, Michael Jonathan.
In: Journal of the American Chemical Society, Vol. 128, No. 9, 08.03.2006, p. 3085-97.Research output: Contribution to journal › Journal article › Research › peer-review
Sensitizer-mediated photooxidation of histidine residues : evidence for the formation of reactive side-chain peroxides. / Agon, Vanessa V; Bubb, William A; Wright, Adam; Hawkins, Clare Louise; Davies, Michael Jonathan.
In: Free Radical Biology & Medicine, Vol. 40, No. 4, 15.02.2006, p. 698-710.Research output: Contribution to journal › Journal article › Research › peer-review
Actions of ultraviolet light on cellular structures. / Pattison, David I; Davies, Michael Jonathan.
In: E X S, No. 96, 2006, p. 131-57.Research output: Contribution to journal › Journal article › Research
- 2005
- Published
Diabetes screening anxiety and beliefs. / Skinner, T. Chas; Davies, M. J.; Farooqi, A. M.; Jarvis, J.; Tringham, J. R.; Khunti, K.
In: Diabetic Medicine, Vol. 22, No. 11, 01.11.2005, p. 1497-1502.Research output: Contribution to journal › Journal article › Research › peer-review
The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme. / Hawkins, Clare Louise; Davies, Michael Jonathan.
In: Chemical Research in Toxicology, Vol. 18, No. 11, 11.2005, p. 1669-77.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation of heparan sulphate by hypochlorite : role of N-chloro derivatives and dichloramine-dependent fragmentation. / Rees, Martin D; Pattison, David I; Davies, Michael Jonathan.
In: Biochemical Journal, Vol. 391, No. Pt 1, 01.10.2005, p. 125-34.Research output: Contribution to journal › Journal article › Research › peer-review
The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation. / Hawkins, Clare Louise; Davies, Michael Jonathan.
In: Free Radical Biology & Medicine, Vol. 39, No. 7, 01.10.2005, p. 900-12.Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of protease inhibitors and lysozyme by hypochlorous acid : role of side-chain oxidation and protein unfolding in loss of biological function. / Hawkins, Clare Louise; Davies, Michael Jonathan.
In: Chemical Research in Toxicology, Vol. 18, No. 10, 10.2005, p. 1600-10.Research output: Contribution to journal › Journal article › Research › peer-review
Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability : a comparison with other osmotic agents and free radical scavengers. / Birinyi-Strachan, Liesl C; Davies, Michael Jonathan; Lewis, Richard J; Nicholson, Graham M.
In: Neuropharmacology, Vol. 49, No. 5, 10.2005, p. 669-86.Research output: Contribution to journal › Journal article › Research › peer-review
Protein oxidation injury occurs during pediatric cardiopulmonary bypass. / Sheil, Meredith L; Luxford, Catherine; Davies, Michael Jonathan; Peat, Jennifer K; Nunn, Graham; Celermajer, David S.
In: Journal of Thoracic and Cardiovascular Surgery, Vol. 130, No. 4, 10.2005, p. 1054-61.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins. / Zeng, Jingmin; Davies, Michael Jonathan.
In: Chemical Research in Toxicology, Vol. 18, No. 8, 08.2005, p. 1232-41.Research output: Contribution to journal › Journal article › Research › peer-review
Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus. / Morgan, Philip E; Sturgess, Allan D; Davies, Michael Jonathan.
In: Arthritis & Rheumatism, Vol. 52, No. 7, 07.2005, p. 2069-79.Research output: Contribution to journal › Journal article › Research › peer-review
Guanine-specific DNA damage induced by gamma-irradiated histone. / Furukawa, Ayako; Hiraku, Yusuke; Oikawa, Shinji; Luxford, Catherine; Davies, Michael Jonathan; Kawanishi, Shosuke.
In: Biochemical Journal, Vol. 388, No. Pt 3, 15.06.2005, p. 813-8.Research output: Contribution to journal › Journal article › Research › peer-review
Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation. / Pattison, David I; Davies, Michael Jonathan.
In: Biochemistry, Vol. 44, No. 19, 17.05.2005, p. 7378-87.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells. / Brown, B E; Dean, R T; Davies, Michael Jonathan.
In: Diabetologia, Vol. 48, No. 2, 02.2005, p. 361-9.Research output: Contribution to journal › Journal article › Research › peer-review
The oxidative environment and protein damage. / Davies, Michael Jonathan.
In: B B A - Reviews on Cancer, Vol. 1703, No. 2, 17.01.2005, p. 93-109.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
Protein-bound kynurenine is a photosensitizer of oxidative damage. / Parker, Nicole R; Jamie, Joanne F; Davies, Michael Jonathan; Truscott, Roger J W.
In: Free Radical Biology & Medicine, Vol. 37, No. 9, 01.11.2004, p. 1479-89.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates. / Rees, Martin D; Hawkins, Clare Louise; Davies, Michael Jonathan.
In: Biochemical Journal, Vol. 381, No. Pt 1, 01.07.2004, p. 175-84.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides. / Winterbourn, Christine C; Parsons-Mair, Helena N; Gebicki, Silvia; Gebicki, Janusz M; Davies, Michael Jonathan.
In: Biochemical Journal, Vol. 381, No. Pt 1, 01.07.2004, p. 241-8.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetic analysis of the reactions of hypobromous acid with protein components : implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress. / Pattison, David I; Davies, Michael Jonathan.
In: Biochemistry, Vol. 43, No. 16, 27.04.2004, p. 4799-809.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protective mechanisms against peptide and protein peroxides generated by singlet oxygen. / Morgan, Philip E; Dean, Roger T; Davies, Michael Jonathan.
In: Free Radical Biology & Medicine, Vol. 36, No. 4, 15.02.2004, p. 484-96.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reactive species formed on proteins exposed to singlet oxygen. / Davies, Michael Jonathan.
In: Photochemical & Photobiological Sciences, Vol. 3, No. 1, 01.2004, p. 17-25.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct detection and quantification of transition metal ions in human atherosclerotic plaques : evidence for the presence of elevated levels of iron and copper. / Stadler, Nadina; Lindner, Robyn A; Davies, Michael Jonathan.
In: Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 24, No. 5, 2004, p. 949-54.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EPR spin trapping of protein radicals. / Davies, Michael Jonathan; Hawkins, Clare Louise.
In: Free Radical Biology & Medicine, Vol. 36, No. 9, 2004, p. 1072-86.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Markers of protein oxidation : different oxidants give rise to variable yields of bound and released carbonyl products. / Headlam, Henrietta A; Davies, Michael Jonathan.
In: Free Radical Biology & Medicine, Vol. 36, No. 9, 2004, p. 1175-84.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Hypochlorite-induced oxidation of amino acids, peptides and proteins. / Hawkins, C L; Pattison, D I; Davies, Michael Jonathan.
In: Amino Acids, Vol. 25, No. 3-4, 12.2003, p. 259-74.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fragmentation of extracellular matrix by hypochlorous acid. / Woods, Alan A; Davies, Michael Jonathan.
In: Biochemical Journal, Vol. 376, No. Pt 1, 15.11.2003, p. 219-27.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines : evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation. / Rees, Martin D; Hawkins, Clare Louise; Davies, Michael Jonathan.
In: Journal of the American Chemical Society, Vol. 125, No. 45, 12.11.2003, p. 13719-33.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles. / Knott, Heather M; Brown, Bronwyn E; Davies, Michael Jonathan; Dean, Roger T.
In: European Journal of Biochemistry, Vol. 270, No. 17, 09.2003, p. 3572-82.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Singlet oxygen-mediated damage to proteins and its consequences. / Davies, Michael Jonathan.
In: Molecular Cell Biology Research Communications, Vol. 305, No. 3, 06.06.2003, p. 761-70.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radical chemistry of epigallocatechin gallate and its relevance to protein damage. / Hagerman, Ann E; Dean, Roger T; Davies, Michael Jonathan.
In: Nitric Oxide: Biology and Chemistry, Vol. 414, No. 1, 01.06.2003, p. 115-20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roles of tyrosine-rich precursor glycoproteins and dityrosine- and 3,4-dihydroxyphenylalanine-mediated protein cross-linking in development of the oocyst wall in the coccidian parasite Eimeria maxima. / Belli, Sabina I; Wallach, Michael G; Luxford, Catherine; Davies, Michael Jonathan; Smith, Nicholas C.
In: Eukaryotic Cell (Online Edition), Vol. 2, No. 3, 06.2003, p. 456-64.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins : absolute rate constants, product analysis, and computational modeling. / Pattison, David I; Hawkins, Clare Louise; Davies, Michael Jonathan.
In: Chemical Research in Toxicology, Vol. 16, No. 4, 04.2003, p. 439-49.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38036205
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Protein oxidation and peroxidation
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
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